Navigation Links
First in the world - Singapore scientists discover genes responsible for cornea blindness
Date:1/16/2013

atening conditions. Eye doctors can in the future through genetic analysis better manage such patients, preventing regression of their conditions.

Prof Aung Tin, Deputy Director, Singapore Eye Research Institute (SERI) and a senior consultant ophthalmologist and Head of Glaucoma Service at Singapore National Eye Centre and a co-author of the paper, said, "This was a tremendous achievement, involving many centres from several countries around the world. Singapore played a major role in this work, especially SERI's population based studies of 10,000 Chinese, Malay and Indian people."

Assoc Prof Eranga Vithana, Associate Director, Basic and Experimental Sciences, SERI and a co-author of the paper, said, "This paper identified 6 novel genetic variants that confer increased risk of keratoconus, a condition for which genes were not very forthcoming prior to this study. It once again underlined the inevitability of large scale collaborative studies to unravel genes for common complex diseases and also the advantage of having well characterized large cohorts."

Assistant Professor Khor Chiea Chuen, Principal Investigator, Division of Human Genetics, Genome Institute of Singapore-an institute of the Agency for Science, Technology and Research (A*STAR) and the paper's co-lead author, said, "Yet again, this paper underscores the power of modern genetic approaches studied in very large sample sizes in revealing the hereditable basis of normal human traits, and how the extremes of which may give rise to common diseases."

Prof Ng Huck Hui, Executive Director of the Genome Institute of Singapore said, "I am very pleased that the Genome Institute of Singapore is a part of an international effort to dissect the genetics of eye conditions such as keratoconus and glaucoma. Genomics remains a very powerful tool to identify the link between genetic variations and phenotypes. This study that focuses on central corneal thickness illustrates the value
'/>"/>

Contact: Winnie Lim
limcp2@gis.a-star.edu.sg
656-808-8013
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. F1000Research, the first Open Science publisher, launches following a successful beta testing phase
2. DNA prefers to dive head first into nanopores
3. First fossil bird with teeth specialized for tough diet
4. The first genome sequence of Chinese plum provides important resource for fruit improvement
5. OpGen announces sequence assembly and finishing of first reference genome of domestic goat
6. The first goat genome sets a good example for facilitating de novo assembly of large genomes
7. First freshwater mosasaur discovered
8. First evidence of fish sensing geomagnetic fields from a Czech Christmas market
9. Africas Homo sapiens were the first techies
10. Surgical Theater, LLC sells first Surgical Rehearsal Platform to UH Case Medical Center
11. First evidence of ocean acidification affecting live marine creatures in the Southern Ocean
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... 1, 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market, announces the second ... is underway to early access pre-order customers. ... at retail outlets including Walmart, Target, AT&T, Dunkin, Donuts, ... was accepted at all outlets and very easy to ...
(Date:4/1/2015)... April 1, 2015   Medisafe ™, the leading ... across iOS and Android smartphones ... biofeedback into the platform to allow patients to track ... the first time, patients will be able to visualize ... impacts important biometrics, such as glucose levels and blood ...
(Date:3/31/2015)...  Elephant Talk Communications Corp. (NYSE MKT: ETAK) ("Elephant ... Defined Network Architecture (ET Software DNA® 2.0) platforms and ... $20.4 million for the year ended December 31, 2014 ... year ended December 31, 2013. At ... its multi-year transition away from its legacy landline business ...
Breaking Biology News(10 mins):NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6
... viruses or parasites attack, immune system cells unleash the ... trigger inflammation, which, if unchecked, can destroy tissue, induce ... let loose another protein compound to cool down the ... operates is unclear. The leading hypothesis is that these ...
... Research Institute (NHGRI), one of the National Institutes ... targets including the Northern white-cheeked gibbon (Nomascus leucogenys), ... sequence the genome of at least one non-human ... along the evolutionary primate tree and making available ...
... The brain's septum helps prevent epileptic seizures by ... another area of the brain known as the ... Journal of Neurophysiology. The researchers found that, by ... rats, they could reduce epileptic seizures by 86-97 ...
Cached Biology News:Research reveals inner workings of immune system 'thermostat' 2NHGRI announces latest sequencing targets 2NHGRI announces latest sequencing targets 3NHGRI announces latest sequencing targets 4NHGRI announces latest sequencing targets 5NHGRI announces latest sequencing targets 6Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent 2Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent 3
(Date:4/1/2015)... Md. , April 1, 2015  Spherix ... company committed to the fostering and monetization of ... LLC, a privately held full service global investment ... recently issued an industry note featuring Spherix. ... , CFA, a Senior Analyst at Chardan, was ...
(Date:4/1/2015)... April 01, 2015 The concept of “spot ... multi-billion dollar industry. Founder of Fasciology, Ashley Black, says that ... of fat, instead of having to wait for the whole ... that “ prior to fat cooling procedures, the only ... contouring, was liposuction, which is a highly invasive procedure.” It ...
(Date:4/1/2015)... 2015 National recruitment firm Slone ... Brad Allen as Head of Sales at Optimal Medicine, ... market. , Allen brings over 20 years experience ... a number of companies including Dell Services Healthcare, Medsphere ... were a perfect fit for accomplishing the goals Optimal ...
(Date:3/31/2015)... CytoSorbents Corporation (NASDAQ CM: CTSO), a ... treat critically-ill and cardiac surgery patients in multiple ... financial results for the fiscal year ending December ... revenues were a record $3.1M, an increase of ... of $0.8M Highlights for the Year Ending December ...
Breaking Biology Technology:Chardan Capital Issues Industry Note Covering Spherix 2Chardan Capital Issues Industry Note Covering Spherix 3Hybrid Health Guru, Ashley Black, announces that her invention The FasciaBlaster™ rivals the “fat cooling” procedures that reduce exercise and diet resistant fat pockets. 2Hybrid Health Guru, Ashley Black, announces that her invention The FasciaBlaster™ rivals the “fat cooling” procedures that reduce exercise and diet resistant fat pockets. 3Slone Partners Fills Head of Sales at Optimal Medicine 2CytoSorbents Reports Record 2014 Revenue 2CytoSorbents Reports Record 2014 Revenue 3CytoSorbents Reports Record 2014 Revenue 4CytoSorbents Reports Record 2014 Revenue 5CytoSorbents Reports Record 2014 Revenue 6CytoSorbents Reports Record 2014 Revenue 7CytoSorbents Reports Record 2014 Revenue 8CytoSorbents Reports Record 2014 Revenue 9CytoSorbents Reports Record 2014 Revenue 10CytoSorbents Reports Record 2014 Revenue 11
... growth company of diversified businesses, ... Transportation Accessories Group has acquired ... zinc plating services. Chem-Chrome is ... has been a longtime processor ...
... Software, worldwide leader in e-document ... Fax and VSI-FAX(R) product families, ... 3.0. This new solution allows ... more efficiently, effectively, and economically ...
... nanoscale device developed by a University of Wisconsin-Madison Engineering ... electrons in such devices as laptop computers and provide ... This device will allow researchers to study ... heat dissipation on single electron transport in transistors. ...
Cached Biology Technology:Cool Computers 2Cool Computers 3
cysteine and glycine-rich protein 2,...
... inhibitor (IC50 = 59.2 M). ... 32 O 13 MolWeight: ... RT CAS: ... Soluble to 100 mM in DMSO IUPAC: ...
HSPBP1 Antibody...
1, 2 or 8 PreMixes are included as part of the FailSafe™ PCR System....
Biology Products: