Navigation Links
Fighting fungal infections with bacteria
Date:4/30/2010

A bacterial pathogen can communicate with yeast to block the development of drug-resistant yeast infections, say Irish scientists writing in the May issue of Microbiology. The research could be a step towards new strategies to prevent hospital-acquired infections associated with medical implants.

Researchers from University College Cork in Ireland studied the interaction between the bacterium Pseudomonas aeruginosa, which is often associated with severe burns, and the yeast Candida albicans, which can grow on plastic surfaces such as catheters. Both microbes are very common and although they are normally harmless to healthy individuals, they can cause disease in immunocompromised people.

The team discovered that molecules produced by P. aeruginosa bacteria were able to hinder the development of C. albicans 'biofilms' on silicone, when the yeast cells clump together on the surface of the plastic. Interestingly, the interaction between the two organisms did not depend on the well-studied bacterial communication system called Quorum Sensing, indicating that a novel signalling mechanism was at play.

C. albicans is the most common hospital-acquired fungal infection and can cause illness by sticking to and colonising plastic surfaces implanted in the body such as catheters, cardiac devices or prosthetic joints. This biofilm formation is a key aspect of C. albicans infection and is problematic as biofilms are often resistant to the antibiotics used to treat them. Dr John Morrissey, who led the team of researchers, said, "Candida albicans can cause very serious deep infections in susceptible patients and it is often found in biofilm form. It is therefore important to understand the biofilm process and how it might be controlled."

Dr Morrissey believes his work may lead to significant clinical benefits. "If we can exploit the same inhibitory strategy that the bacterium P. aeruginosa uses, t
'/>"/>

Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Social habits of cells may hold key to fighting diseases
2. When it comes fighting to C. difficile, the Palme dOr goes to soap and warm water
3. Fighting the spread of food poisoning
4. Gold nanorods shed light on new approach to fighting cancer
5. UV light improving chances of fighting cancer
6. Researchers uncover key trigger for potent cancer-fighting marine product
7. Fighting pollution the poplar way: Trees to clean up Indiana site
8. Fighting Aussie yabbies dont forget a face -- new research by the University of Melbourne
9. Strengthening the tumor-fighting ability of T cells
10. FSU researcher using computers to hone cancer-fighting strategies
11. UCSB study finds physical strength, fighting ability revealed in human faces
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fighting fungal infections with bacteria
(Date:9/30/2014)... -- Winners of The Economist,s prestigious Innovation awards 2014 ... place at the JW Marriott Hong Kong on Friday, October 10 ... their experiences and the lessons those hold for others. The awards, ... the past decade, will be presented at a ceremony in ... will be the first time the ceremony has come to ...
(Date:9/29/2014)... September 29, 2014 -- Plants have a symbiotic ... the pants extract nutrients and defend against invaders ... contaminating fruits and vegetables. Now, scientist have discovered ... of seeds; thus ensuring that sprouting plants are ... University of Notre Dame, presented their findings today ...
(Date:9/29/2014)... school? According to a new Food and Brand Lab ... can increase participation in the National School Lunch Program ... vegetables by 16%! , Chefs Move to Schools (CMTS), ... chefs with schools in order to provide nutrition instruction ... service workers. , A CMTS event was held in ...
Breaking Biology News(10 mins):Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 3Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 4Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 5Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 6Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 7Plants prepackage beneficial microbes in their seeds 2Chefs move to schools can increase school meal participation and vegetable intake among students 2
... One out of three sexually active older adults infected with ... University researchers. A survey of 260 HIV-positive older adults found ... and were in a relationship. , AIDs cases among the ... for Disease Control and Prevention, they will account for half ...
... has stopped in its tracks a form of blood ... telomerase, thereby shortening the ends of chromosomes, called telomeres. ... commits suicide as a means of protecting the body," ... molecular biology and genetics at Johns Hopkins. Her study, ...
... instructions rather than drugs to treat disease - has tickled ... therapeutic method. One sizeable hurdle is getting the right ... Engineers at the University of Wisconsin-Madison are now developing a ... his colleagues have created ultrathin, nanoscale films composed of DNA ...
Cached Biology News:1/3 of sexually active older adults with HIV/AIDs has unprotected sex 2Short chromosomes put cancer cells in forced rest 2Ultrathin films deliver DNA as possible gene therapy tool 2Ultrathin films deliver DNA as possible gene therapy tool 3
(Date:9/30/2014)... Genedata, a leading provider ... and related life science research, today announced ... Selector as its host-pathogen data analysis platform ... a European consortium dedicated to improving the ... anti-fungal drug therapies. Genedata Selector supports this ...
(Date:9/30/2014)... iLab Solutions announced the results of ... which focuses on core facility operations, growth and utilization ... today. , In its 4th year running, a number ... the year-over-year decrease in the percentage of revenue that ... feeling the constraints of this trend. When asked, “What ...
(Date:9/30/2014)... September 30, 2014 Rainbow Scientific, ... research products, recently opened an online store to ... culture product lines developed and manufactured by Biological ... store include Biological Industries’ Nutristem® serum-free, xeno-free reagents ... embryonic stem cell (hESC) culture. , The ...
(Date:9/30/2014)... Cambridge MA and Pittsburgh PA (PRWEB) September 30, ... of Clinical Research Nurses ( IACRN), a ... Alliance for Clinical Research Excellence and Safety ... announced the signing of a strategic alliance agreement, ... , IACRN’s vision is to enhance clinical research ...
Breaking Biology Technology:FUNGITECT Consortium Adopts Genedata Selector as Data Analysis Platform for Anti-fungal R 2FUNGITECT Consortium Adopts Genedata Selector as Data Analysis Platform for Anti-fungal R 3iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 3Rainbow Scientific, Inc. opens online store for state-of-the-art stem cell culture and cytogenetic reagents 2IACRN and ACRES to Support Clinical Research Nurses 2IACRN and ACRES to Support Clinical Research Nurses 3
... , TAI,AN, China, Sept. ... Board: CBPO) ("China Biologic," or the "Company"),one of ... of China ("PRC"), today announced that on September ... and development agreement with the,Institute of Blood Transfusion ...
... , , ABBOTT PARK, Ill., Sept. 24 ... results on Wednesday, Oct. 14, 2009, before the market opens. , ... of the earnings conference call at 8 a.m. Central time (9 a.m. Eastern), ... An archived edition of the call will be available after 11 a.m. Central ...
... ... The increased need for pharmaceutical packaging companies to reduce waste and disposal ... led to an increased demand for specialised deblistering machines according ... Press-Outs, are used to increase production yields by recovering valuable product from ...
Cached Biology Technology:China Biologic Products Enters into a Strategic Research and Development Agreement with IBT of CAMS 2China Biologic Products Enters into a Strategic Research and Development Agreement with IBT of CAMS 3China Biologic Products Enters into a Strategic Research and Development Agreement with IBT of CAMS 4Deblistering Device Keeps Production Ahead Of Pack 2Deblistering Device Keeps Production Ahead Of Pack 3