Navigation Links
Fighting bacteria with a new genre of antibodies
Date:4/24/2013

In an advance toward coping with bacteria that shrug off existing antibiotics and sterilization methods, scientists are reporting development of a new family of selective antimicrobial agents that do not rely on traditional antibiotics. Their report on these synthetic colloid particles, which can be custom-designed to recognize the shape of specific kinds of bacteria and inactivate them, appears in the Journal of the American Chemical Society.

Vesselin Paunov and colleagues point out that many bacteria have developed resistance to existing antibiotics. They sought a new approach one that bacteria would be unable to elude by mutating into drug-resistant forms. Their inspiration was the antibodies that the immune system produces when microbes invade the body. Those antibodies patrol the body for microbes and bind to their surfaces, triggering a chain of events in which the body's immune system attacks and destroys the microbes.

Paunov's team describes development and successful tests of synthetic colloid particles, called "colloid antibodies." Colloids are materials in which tiny particles of one material are dispersed in another material. Milk is a colloid in which globules of fat are spread throughout water and other materials. The colloid antibody particles are shells packed with a killing agent. They are designed to recognize and bind to specific bacteria.

Laboratory experiments showed that the colloid antibodies attached to and inactivated only their intended targets without harming other cells. "We anticipate that similar shape selective colloid antibodies can potentially become a powerful weapon in the fight against antibiotic-resistant bacteria," say the researchers. "They can also find applications as non-toxic antibacterial agents, preventing growth of harmful bacteria in various formulations."


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Fighting GM crop vandalism with a government-protected research site
2. Scientists find bone-marrow environment that helps produce infection-fighting T and B cells
3. Compound stimulates tumor-fighting protein in cancer therapy
4. University of Tennessee researchers find fungus has cancer-fighting power
5. Compound in grapes, red wine could be key to fighting prostate cancer
6. Fighting melanomas attraction to the brain
7. Research finds novel airborne germ-killing oral spray effective in fighting colds and flu
8. Nematodes with pest-fighting potential identified
9. Method to prevent rejection of disease-fighting proteins described in Human Gene Therapy journal
10. La Jolla institute identifies critical cell in fighting E. coli infection
11. UGA study reveals flu-fighting role for well-known immune component
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... the Entomological Society of America (ESA) has elected ten ... as a Fellow acknowledges outstanding contributions to entomology in ... or administration. The following Fellows will be recognized during ... will be held November 16-19, 2014 in Portland, Oregon. ... professor with the Department of Plant, Soil and Entomological ...
(Date:7/30/2014)... received a pledge of $1 million from the Cornelia ... new Neurobehavioral Biometry Center. , The newly ... the Laboratory to develop a greater breadth and depth ... of accelerating the pace of research to improve human ... premier resource for the Laboratory and its external partners, ...
(Date:7/30/2014)... shrinking ranges and a changing climate threaten some ... plants, and so conservationists establish seed collections to ... in hopes of preserving some genetic diversity., For ... simple models that offer a one-size-fits-all approach for ... saving 50 seed samples regardless of species, pollination ...
Breaking Biology News(10 mins):Entomological Society of America recognizes 2014 fellows 2Entomological Society of America recognizes 2014 fellows 3Entomological Society of America recognizes 2014 fellows 4Entomological Society of America recognizes 2014 fellows 5Entomological Society of America recognizes 2014 fellows 6Entomological Society of America recognizes 2014 fellows 7Entomological Society of America recognizes 2014 fellows 8Entomological Society of America recognizes 2014 fellows 9Entomological Society of America recognizes 2014 fellows 10Entomological Society of America recognizes 2014 fellows 11Entomological Society of America recognizes 2014 fellows 12Entomological Society of America recognizes 2014 fellows 13Entomological Society of America recognizes 2014 fellows 14Entomological Society of America recognizes 2014 fellows 15Entomological Society of America recognizes 2014 fellows 16Entomological Society of America recognizes 2014 fellows 17Rossi Foundation pledges $1M for JAX neurobehavioral research center 2Saving seeds the right way can save the world's plants 2
... to biobanks vast collections of human tissue samples that ... have a right to basic information about how their donations ... a new paper. The idea behind biobanks is that ... to medical records and other health information, can yield discoveries ...
... and terrorist plots are usually the preserve of Hollywood ... is the stuff of real life. As controversy about ... new paper argues for a complete overhaul of current ... Reconfiguring Global Responses to Influenza, by Dr Paul Forster, ...
... modify their body movements to be in tune with others, ... to be in synchrony with their peers. For example, we ... unison at the end of a concert. This phenomenon is ... the RIKEN Brain Science Institute report today that pairs of ...
Cached Biology News:Safeguards needed for tissue donors 2Pandemic controversies: The global response to pandemic influenza must change 2Primates too can move in unison 2
(Date:7/30/2014)... 2014 W. R. Grace & ... the REVELERIS® Prep purification system , a ... and other researchers to perform both flash and ... , With the REVELERIS® Prep purification system, researchers ... modes with a simple touch of the screen, ...
(Date:7/30/2014)... 30, 2014  Decision Resources Group finds that ... in the United States ... penetration will be the level of savings achievable ... expected lower cost to patients. Payers plan to ... their pricing expectations in order to encourage physician ...
(Date:7/30/2014)... FRANCISCO , July 30, 2014 ... Congress evaluated the safety and efficacy of CSL ... rejection following kidney transplants in highly sensitized patients. ... inhibitor of the complement system. The ... in significant increases in the levels of complement ...
(Date:7/30/2014)... July 30, 2014  The Chicago Bears are excited ... of Dermatology (Academy) in an effort to raise awareness ... will host free SPOT me™ skin cancer screenings at ... Soldier Field. SPOT me™ is an educational campaign ... dangers and risks of skin cancer, and encourages people ...
Breaking Biology Technology:Grace Launches New REVELERIS® Prep Purification System 2Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 2Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 3Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 2Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 3Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 2Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 3Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 4
... OpGen , a company that makes optical tests capable ... the final stage of its $5 million investment round. ... Wisconsin-Madison technology, already sells its testing services to a ... between marketing that service and new developments such as ...
... toilet seat. Seriously. The Brondell Swash 600. But then controversy ... toilet seat in the first place. , ,Last fall I ... This group, organized by networker extraordinaire and Stonebrick Group founder ... virtue of their work or their own networking prowess, presumably ...
... Jim Doyle has appointed Mary Burke, who was most recently ... Bicycles , to be the state's next commerce secretary starting ... end of 2004 to take a job with a law ... Doyle's business-plan contest will stop accepting submissions after January 31. ...
Cached Biology Technology:OpGen completes $5 million investment round 2The myth of objectivity 2The myth of objectivity 3
...
Coverslips for Microarrays, 1. *Category: MICROARRAY ACCESSORIES....
S. O'Hare & C.K. Atterwill • In vitro toxicity techniques for regular lab use. Ex vivo techniques are also covered with the aim of reducing and refining the use of animals in the future....
... The ScriptCap™ 2'-O-Methyltransferase converts Cap 0 (or ... The Cap 1 structure has been shown ... up to 50%. This improvement is seen ... ScriptCap™ m7G Capping System as well as ...
Biology Products: