Navigation Links
Fighting bacteria with a new genre of antibodies
Date:4/24/2013

In an advance toward coping with bacteria that shrug off existing antibiotics and sterilization methods, scientists are reporting development of a new family of selective antimicrobial agents that do not rely on traditional antibiotics. Their report on these synthetic colloid particles, which can be custom-designed to recognize the shape of specific kinds of bacteria and inactivate them, appears in the Journal of the American Chemical Society.

Vesselin Paunov and colleagues point out that many bacteria have developed resistance to existing antibiotics. They sought a new approach one that bacteria would be unable to elude by mutating into drug-resistant forms. Their inspiration was the antibodies that the immune system produces when microbes invade the body. Those antibodies patrol the body for microbes and bind to their surfaces, triggering a chain of events in which the body's immune system attacks and destroys the microbes.

Paunov's team describes development and successful tests of synthetic colloid particles, called "colloid antibodies." Colloids are materials in which tiny particles of one material are dispersed in another material. Milk is a colloid in which globules of fat are spread throughout water and other materials. The colloid antibody particles are shells packed with a killing agent. They are designed to recognize and bind to specific bacteria.

Laboratory experiments showed that the colloid antibodies attached to and inactivated only their intended targets without harming other cells. "We anticipate that similar shape selective colloid antibodies can potentially become a powerful weapon in the fight against antibiotic-resistant bacteria," say the researchers. "They can also find applications as non-toxic antibacterial agents, preventing growth of harmful bacteria in various formulations."


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Fighting GM crop vandalism with a government-protected research site
2. Scientists find bone-marrow environment that helps produce infection-fighting T and B cells
3. Compound stimulates tumor-fighting protein in cancer therapy
4. University of Tennessee researchers find fungus has cancer-fighting power
5. Compound in grapes, red wine could be key to fighting prostate cancer
6. Fighting melanomas attraction to the brain
7. Research finds novel airborne germ-killing oral spray effective in fighting colds and flu
8. Nematodes with pest-fighting potential identified
9. Method to prevent rejection of disease-fighting proteins described in Human Gene Therapy journal
10. La Jolla institute identifies critical cell in fighting E. coli infection
11. UGA study reveals flu-fighting role for well-known immune component
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015  A man-made form of insulin delivered by nasal ... in adults with mild cognitive impairment and Alzheimer,s disease ... at Wake Forest Baptist Medical Center. The ... cognitive impairment (MCI) or mild to moderate Alzheimer,s dementia ...
(Date:1/22/2015)... Jan. 22, 2015 Research and Markets ... the "Global Wearable Technologies Market and Applications, ... Trends and Forecast 2014-2020" report to their ... smart devices that can be worn on the ...
(Date:12/22/2014)... Research and Markets ( http://www.researchandmarkets.com/research/fx4bg3/the_global ) ... Global Watermarking and Fingerprinting Markets" report to ... This insight provides an overview ... markets. Watermarking aims to control and monitor piracy ...
Breaking Biology News(10 mins):Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 2The Global Watermarking and Fingerprinting Markets 2
... spinal cord injury is receiving attention in the research ... department of biomedical engineering at NJIT, recently has published ... stimulators for individuals with spinal cord injuries. ... of support from a four-year, $1.4 million National Institutes ...
... Inc. (Nasdaq: AWRE ), a global provider ... of the Next-Generation Universal Automated Booking Station, or "Universal ... of Justice. Universal ABS is a biometric enrollment application ... modular, COTS software framework that is far more easily ...
... S.C., Oct. 17, 2011 Integrated Biometrics, a South ... announced today that they have launched a new FBI ... device has been tested by The MITRE Corporation and ... Certified Product List. Watson is the world,s first non-optical ...
Cached Biology News:NJIT researcher testing micro-electronic stimulators for spinal cord injuries 2Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 2Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 3Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 4The World's First Non Optical FBI Appendix F Certified Fingerprint Sensor 2
(Date:1/22/2015)... BRUNSWICK , Nueva Jersey , 22 de ... Award for Biomedical Research abre hoy su llamada a ... personas cuya investigación científica ha hecho, o tiene el ... la salud humana. Las nominaciones se aceptarán hasta el ...
(Date:1/22/2015)... , Jan. 22. 2015  Varian Medical Systems (NYSE: ... has been honored for its commitment to sustainability with inclusion ... Varian is the highest ranked healthcare equipment company among the ... during the World Economic Forum at Davos, Switzerland ...
(Date:1/22/2015)... , Jan. 22, 2015  Derma Sciences, Inc. (Nasdaq: ... focused on advanced wound care, announces that AMNIOEXCEL® ... have been added to the Premier, Inc. Regenerative ... opportunity for the AMNIOEXCEL® and AMNIOMATRIX® product lines, ...
(Date:12/24/2014)... , Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... MDT ) has submitted a pre-market approval ... for the use of Medtronic,s SynchroMed ® II ... for use with United Therapeutics, Remodulin ® (treprostinil) ...
Breaking Biology Technology:El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Varian Honored Among World's 100 Most Sustainable Corporations 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4
... is available in Spanish . , Scientists ... characterized for the first time different antioxidant compounds from foods ... called Teucrium polium. They have used two new techniques, capillary ... to identify and quantify a great part of the phenolic ...
... OMAHA, Neb. , Feb. 5 Transgenomic, Inc. (OTC ... Chief Executive Officer, will be presenting a corporate overview of the company ... take place at 11:30 a.m. EST on Tuesday, February ... City , NY. , About Transgenomic, Inc. ...
... published today in Science , by researchers at ... Office, the Natural Resources Institute, and the Universities of ... flight behaviours that enable insects to undertake long-distance migrations, ... , Many insects avoid cold British winters by migrating ...
Cached Biology Technology:New antioxidant compounds have been identified in foods such as olive oil, honey and nuts 2Transgenomic Presents at 12th Annual BIO CEO & Investor Conference 2Migrating insects fly in the fast lane 2
Rabbit polyclonal to MA2 ( Abpromise for all tested applications). entrezGeneID: 10687 SwissProtID: Q9UL42...
... FANCM ( Abpromise for all tested ... peptide derived from within residues 2000 to ... the amino acid sequence is proprietary) ... .) Entrez GeneID: ...
Mouse monoclonal [YPF19] to Yersinia pestis ( Abpromise for all tested applications)....
Rabbit polyclonal to 13,14 dihydro 15 keto Prostaglandin E2 ( Abpromise for all tested applications)....
Biology Products: