Navigation Links
Fighting antibiotic resistance with 'molecular drill bits'
Date:3/17/2014

DALLAS, March 17, 2014 In response to drug-resistant "superbugs" that send millions of people to hospitals around the world, scientists are building tiny, "molecular drill bits" that kill bacteria by bursting through their protective cell walls. They presented some of the latest developments on these drill bits, better known to scientists as antimicrobial peptides (AMPs), at the 247th National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society.

The meeting, which features more than 10,000 scientific reports across disciplines from energy to medicine, continues here through Thursday.

One of the researchers in the search for new ways to beat pathogenic bacteria is Georges Belfort, Ph.D. He and his team have been searching for a new therapy against the bacteria that cause tuberculosis (TB). It's a well-known, treatable disease, but resistant strains are cropping up. The World Health Organization estimates that about 170,000 people died from multidrug-resistant TB in 2012.

"If the bacteria build resistance to all current treatments, you're dead in the water," said Belfort, who is at Rensselaer Polytechnic Institute.

To avoid this dire scenario, scientists are developing creative ways to battle the disease. In ongoing research, Belfort's group together with his wife, Marlene Belfort, and her group at the University at Albany are trying to dismantle bacteria from within. They also decided to attack it from the outside.

In their search for a way to do this, they came upon AMPs. Although these naturally occurring, short strings of amino acids are not new all classes of organisms from humans to bacteria produce them as part of their natural defense strategy the fight against drug-resistant pathogens has heightened attention on these protective molecules.

Researchers began studying them in earnest in the 1980s. By 2010, they had identified nearly 1,000 unique AMP
'/>"/>

Contact: Michael Bernstein
214-853-8005 (Dallas Press Center, March 14-19)
202-872-6042
m_bernstein@acs.org

Contact: Katie Cottingham, Ph.D.
214-853-8005 (Dallas Press Center, March 14-19)
301-775-8455
k_cottingham@acs.org

American Chemical Society


Source:Eurekalert

Page: 1 2

Related biology news :

1. Preventing home invasions means fighting side-by-side for coral-dwelling crabs and shrimp
2. Study finds cancer-fighting goodness in cholesterol
3. Trial launched into curry chemicals cancer-fighting properties
4. Canadian girl, 16, invents disease-fighting, anti-aging compound using tree particles
5. Fighting bacterias strength in numbers
6. UGA study reveals flu-fighting role for well-known immune component
7. La Jolla institute identifies critical cell in fighting E. coli infection
8. Method to prevent rejection of disease-fighting proteins described in Human Gene Therapy journal
9. Nematodes with pest-fighting potential identified
10. Research finds novel airborne germ-killing oral spray effective in fighting colds and flu
11. Fighting melanomas attraction to the brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... November 4, 2014   ... growth   Fuel3D , a developer of ... funding round totaling $6.4 million (£4 million). This funding builds ... earlier this year and paves the way for the commercial ... The funding round was led by Chimera Partners and ...
(Date:11/4/2014)...   Neurotechnology , a provider of high-precision ... version of its fingerprint matching algorithm has achieved ... evaluation organized by NIST. The MINEX test measures ... 378 fingerprint standard template format. MINEX compliance is ... the United States and ...
(Date:11/3/2014)... Center study published in this month,s ... the activity of a recently discovered communication molecule of ... has been known to limit inflammation and the current ... IL-37 inhibits the ability of the immune system to ... that underlies IL-37,s effect on the immune system now ...
Breaking Biology News(10 mins):Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3PNAS: From HIV to cancer, IL-37 regulates immune system 2
... has long been known that distinctive blue flashes--a type ... environments are caused by tiny, unicellular plankton known as ... time, detailed the potential mechanism for this bioluminesence. ... Science Foundation, is reported by Susan Smith of Emory ...
... Scientists are reporting that household washing machines seem to ... bits of polyester and acrylic smaller than the head ... on ocean shorelines worldwide. Their report describing this potentially ... & Technology . Mark Browne and colleagues explain ...
... the science of sound will be featured at the 162nd ... 31 November 4, 2011, at the Town and Country ... research spanning a diverse array of disciplines, including medicine, music, ... to attend the meeting free of charge. Registration information is ...
Cached Biology News:Explanation for glowing seas suggested 2Sound research at acoustical society meeting 2Sound research at acoustical society meeting 3Sound research at acoustical society meeting 4Sound research at acoustical society meeting 5Sound research at acoustical society meeting 6Sound research at acoustical society meeting 7Sound research at acoustical society meeting 8Sound research at acoustical society meeting 9Sound research at acoustical society meeting 10Sound research at acoustical society meeting 11
(Date:11/21/2014)... The report, "Synthetic Biology ... Cloning kits), Technology (Bioinformatics, Nanotechnology, Gene Synthesis, ... Bioremediation) - Global Forecast to 2018", analyses ... opportunities, and challenges. , Browse 99 market ... 185 pages and in-depth TOC of the ...
(Date:11/21/2014)... Los Angeles, CA (PRWEB) November 21, 2014 ... is it that makes Albert Einstein so instantly recognizable? ... South African-born physicist, mathematician, astronomer and author Hilton Ratcliffe ... that they have nothing at all to do with ... ( Muse Harbor Publishing , November 21, 2014), Ratcliffe ...
(Date:11/21/2014)... Polaris Group announced today that the ... 1 trial of ADI-PEG 20 in combination with ... pleural mesothelioma (MPM) and non-squamous non-small cell lung ... ADI-PEG 20, both as monotherapy and in combination ... other indications, including breast cancer, melanomas, ovarian cancer, ...
(Date:11/21/2014)... 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") today ... September 30, 2014.  Biorem,s complete 2014 third quarter financial statements and ... Financial Summary:Three-months ended September 30, , Nine-months ended ... , 2014 , 2013 , 2014 ... 5,281 , 6,715 , 14,476 Gross profit ...
Breaking Biology Technology:Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 2Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 4“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 2“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 3“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 4Polaris Group Announces Treatment of First Patient in Phase 1 Study of ADI-PEG 20 plus Pemetrexed and Cisplatin in Malignant Pleural Mesothelioma And Non-Squamous Non-Small Cell Lung Carcinoma 2Biorem Reports Third Quarter Results 2Biorem Reports Third Quarter Results 3
... the Association of ... Chinese Canadian Entrepreneurs, TORONTO, April 7 ... and developing the next wave of,antibody therapeutics, today announced that ... "Most Innovative" award at the,Chinese Canadian Entrepreneur Awards, held on ...
... today that,it received notice from Israel,s Chief Scientist,s Office ... D-Pharm,s R&D programs with a,total grant of up to ... PhD, CEO and President of D-Pharm, said "We are ... its firm support over the years,from the time of ...
... computer contains two different types of components: magnetic components, ... logic operations. A University of Missouri researcher, as part ... these two functions in a single hybrid material. This ... logical functions and is expected to permit the design ...
Cached Biology Technology:ARIUS recognized for entrepreneurial excellence 2D-Pharm Secures Funding From Israel's Chief Scientist's Office 2Hybrid computer materials may lead to faster, cheaper technology 2