Navigation Links
Fighting antibiotic resistance with 'molecular drill bits'
Date:3/17/2014

DALLAS, March 17, 2014 In response to drug-resistant "superbugs" that send millions of people to hospitals around the world, scientists are building tiny, "molecular drill bits" that kill bacteria by bursting through their protective cell walls. They presented some of the latest developments on these drill bits, better known to scientists as antimicrobial peptides (AMPs), at the 247th National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society.

The meeting, which features more than 10,000 scientific reports across disciplines from energy to medicine, continues here through Thursday.

One of the researchers in the search for new ways to beat pathogenic bacteria is Georges Belfort, Ph.D. He and his team have been searching for a new therapy against the bacteria that cause tuberculosis (TB). It's a well-known, treatable disease, but resistant strains are cropping up. The World Health Organization estimates that about 170,000 people died from multidrug-resistant TB in 2012.

"If the bacteria build resistance to all current treatments, you're dead in the water," said Belfort, who is at Rensselaer Polytechnic Institute.

To avoid this dire scenario, scientists are developing creative ways to battle the disease. In ongoing research, Belfort's group together with his wife, Marlene Belfort, and her group at the University at Albany are trying to dismantle bacteria from within. They also decided to attack it from the outside.

In their search for a way to do this, they came upon AMPs. Although these naturally occurring, short strings of amino acids are not new all classes of organisms from humans to bacteria produce them as part of their natural defense strategy the fight against drug-resistant pathogens has heightened attention on these protective molecules.

Researchers began studying them in earnest in the 1980s. By 2010, they had identified nearly 1,000 unique AMP
'/>"/>

Contact: Michael Bernstein
214-853-8005 (Dallas Press Center, March 14-19)
202-872-6042
m_bernstein@acs.org

Contact: Katie Cottingham, Ph.D.
214-853-8005 (Dallas Press Center, March 14-19)
301-775-8455
k_cottingham@acs.org

American Chemical Society


Source:Eurekalert

Page: 1 2

Related biology news :

1. Preventing home invasions means fighting side-by-side for coral-dwelling crabs and shrimp
2. Study finds cancer-fighting goodness in cholesterol
3. Trial launched into curry chemicals cancer-fighting properties
4. Canadian girl, 16, invents disease-fighting, anti-aging compound using tree particles
5. Fighting bacterias strength in numbers
6. UGA study reveals flu-fighting role for well-known immune component
7. La Jolla institute identifies critical cell in fighting E. coli infection
8. Method to prevent rejection of disease-fighting proteins described in Human Gene Therapy journal
9. Nematodes with pest-fighting potential identified
10. Research finds novel airborne germ-killing oral spray effective in fighting colds and flu
11. Fighting melanomas attraction to the brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2015)... , Aug. 19, 2015  VOXX International Corporation ... has entered into a Definitive Agreement to purchase ... iris authentication market leader EyeLock through an acquiring ... have a controlling interest in the acquiring entity. ... completion of due diligence.  Expanding on its existing ...
(Date:8/12/2015)... August 12, 2015 As the ... payment innovation and advanced biometrics technology is accelerating beyond ... consumers rely on using their credit cards, the digital ... future for payment services led by companies in the ... :  Google, Inc. (NASDAQ: GOOG ), Apple Inc. ...
(Date:8/10/2015)... The latest 364 page report from business intelligence ... border security market . Visiongain assesses that ... Now: Border security is hard to achieve and harder ... issue you need to know about - and more importantly, ... how this will impact your company and the border security ...
Breaking Biology News(10 mins):VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 2VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 3VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 4VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9
... of Medicine researchers have discovered how the membrane protein ... this protein becomes desensitized so that one no longer ... an advance online publication by Nature Neuroscience, focused on ... found in many other receptors, including ones involved in ...
... self-replicating, mineralizing agent, has been identified by National Aeronautics ... in kidney stone formation among astronauts. With the potential ... Mars, longer missions, and exposure to the elements of ... , To further comprehend the implications of NB, trials ...
... sclerosis (MS) can be an unpredictable disease. It ... nerve cells and disrupts normal nerve signaling. Patients ... pain, fatigue, and blurred vision—that can appear independently ... appear in no particular order, flare-ups are common ...
Cached Biology News:Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients 2
(Date:9/2/2015)... ... September 02, 2015 , ... Drug ... plant-derived compounds. BCC Research reveals in its new report that the U.S. ... defines the category and generates the most market demand. , BCC Research ...
(Date:9/2/2015)... , Sept. 2, 2015 Veracyte, Inc. ... H. Anderson , president and chief executive officer, will ... Wednesday, September 16, 2015 at 10:30 a.m. ET in ... The live audio webcast and subsequent replay may ... webcast will be available shortly after conclusion of the ...
(Date:9/2/2015)... ... September 02, 2015 , ... Advancing in ... surgeries. From vital sign monitoring in ICU to 3D skull printing analysis for ... make real-time clinical decisions with simultaneous access to high precision medical images and ...
(Date:9/2/2015)... ... 2015 , ... Genedata, a leading provider of advanced software ... ® version 13.0 at ELRIG Drug Discovery 2015. This latest version of the ... new capabilities. Screener now supports High Throughput Flow Cytometry (HT-Flow) and Drug Metabolism ...
Breaking Biology Technology:Plant-derived Compounds Poised to Assume Greater Role in Global Drug Markets, According to BCC Research 2Plant-derived Compounds Poised to Assume Greater Role in Global Drug Markets, According to BCC Research 3Veracyte to Present at Morgan Stanley Global Healthcare Conference 2Surgical Workstation Powered by 6th Gen. Intel® Core™ Skylake Processors 2Surgical Workstation Powered by 6th Gen. Intel® Core™ Skylake Processors 3New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 2New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 3New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 4
... Upregulation by Percutaneous Administration of Gene Therapy in ... Effects of SERCA2a Enzyme Replacement Using Gene TransferSAN ... the publication of results from a Phase 1/2 ... replacement therapy for advanced heart failure, in the ...
... a DNA sequencing technology company, announced a definitive ... equity investment in the company. Prompting its decision ... novel reversible terminator chemistry, Lightning Terminators (TM), ... its chemistry as reagent kits to the market ...
... Inc. announced today that it has entered into ... NYSE: SNY ), providing the global ... platform for the research, development and commercialization of ... (ADCC). "We are extremely pleased about our partnership ...
Cached Biology Technology:The Journal of Cardiac Failure Publishes Results From Celladon Corporation's First-in-Human Phase 1/2 Clinical Trial in Advanced Heart Failure 2The Journal of Cardiac Failure Publishes Results From Celladon Corporation's First-in-Human Phase 1/2 Clinical Trial in Advanced Heart Failure 3SeqWright to Invest in LaserGen's Novel Lightning Terminators(TM) 2BioWa Announces License of POTELLIGENT(R) Technology to sanofi-aventis 2
Mouse monoclonal [SH-A1] to S100 alpha ( Abpromise for all tested applications). entrezGeneID: 6271 SwissProtID: P23297...
This application changes sensitive keywords in an FCS file to remove patient information. It was contributed by Dr. David Miller....
Rat monoclonal [HK5.3] to B7 RP1 (Biotin) ( Abpromise for all tested applications). entrezGeneID: 23308 SwissProtID: O75144...
Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXS6673E protein). [Source:Uniprot/SWISSPROT;Acc:Q14202] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: