Navigation Links
Faster DNA analysis at room temperature
Date:8/3/2010

This release is also available in Chinese.

College Park, MD (August 3, 2010) -- DNA microarrays are one of the most powerful tools in molecular biology today. The devices, which can be used to probe biological samples and detect particular genes or genetic sequences, are employed in everything from forensic analysis to disease detection to drug development.

Now Paul Li and colleagues at Simon Fraser University in Burnaby, Canada have combined DNA microarrays with microfluidic devices, which are used for the precise control of liquids at the nanoscale. In an upcoming issue of the journal Biomicrofluidics, which is published by the American Institute of Physics (AIP), Li and his colleagues describe how the first combined device can be used for probing and detecting DNA.

The key to Li's result: gold nanoparticles. Suspended in liquid and mixed with DNA, the nanometer-scale spheres of gold act as mini magnets that adhere to each of the DNA's twin strands. When the DNA is heated, the two strands separate, and the gold nanoparticles keep them apart, which allows the single strands to be probed with other pieces of DNA that are engineered to recognize particular sequences.

Li, whose work is funded by the Natural Sciences and Engineering Research Council of Canada, is applying for a patent for his technique. He sees a host of benefits from the combination of DNA microarrays and microfluidics.

"It's faster and requires a relatively small sample," he says, adding in his paper that "the whole procedure is accomplished at room temperature in an hour and apparatus for high temperature is not required"


'/>"/>

Contact: Jason Socrates Bardi
jbardi@aip.org
301-209-3091
American Institute of Physics
Source:Eurekalert  

Page: 1

Related biology news :

1. Synthetic bone graft recruits stem cells for faster bone healing
2. Faster Salmonella detection now possible with new technique
3. UCLA engineers develop faster method to detect bacterial contamination in coastal waters
4. Chubby birds get there faster
5. ASU scientists develop universal DNA reader to advance faster, cheaper sequencing efforts
6. Ecologists discover forests are growing faster
7. Boston University reseachers develop faster, cheaper DNA sequencing method
8. Faster, cheaper way to find disease genes in human genome passes initial test
9. Faster, more cost-effective DNA test for crime scenes, disease diagnosis
10. Mice run faster on high-grade oil
11. The faster they come
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Faster DNA analysis at room temperature
(Date:9/2/2015)... 2, 2015 Biometric ... in a system which uses identical human characteristic ... vein, DNA and finger print. Increasing number of ... such system which provides high level of security. ... and tokens are vulnerable to attacks. Furthermore, Biometric ...
(Date:8/26/2015)... , August 26, 2015 ... Four, and Five Factor), Application (Travel & Immigration, Government, ... - Global Forecast to 2020", published by MarketsandMarkets, Multi-Factor ... by 2020, growing at a CAGR of 17.7% between ... and 82 F igures spread through 169 ...
(Date:8/20/2015)... , Aug. 20, 2015   Sensory, ... on improving the user experience and security of ... technologies, today announced that its TrulySecure™ ... authentication software to be FIDO Certified™. ... for compliance with the FIDO UAF (Universal Authentication ...
Breaking Biology News(10 mins):Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 2Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 3Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 4Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 2Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 3Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 4Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 5TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5
... scans to measure blood flow in the lungs of people ... are most at risk of emphysema before the disease damages ... University of Iowa study. The study found that smokers ... normal lung function, have very different blood flow patterns in ...
... Chronix Biomedical today announced publication of a study ... tests to predict clinical status and monitor disease activity ... Chronix Biomedical uses proprietary technology to identify disease-specific genetic ... into the bloodstream by damaged and dying cells. ...
... 2010) -- A scientist at Barrow Neurological Institute in Phoenix ... Association (MDA) to continue his groundbreaking work in the disease ... part of MDA,s ongoing commitment to fund neuromuscular research that ... and related diseases. Including this funding, the MDA has ...
Cached Biology News:New test could identify smokers at risk of emphysema 2Chronix Biomedical's serum DNA assays monitor disease activity and treatment response in MS 2Chronix Biomedical's serum DNA assays monitor disease activity and treatment response in MS 3Barrow scientist receives $450K MDA grant 2
(Date:9/4/2015)... DUBLIN , Sep. 04, 2015 ... has announced the addition of the "Biopreservation ... - Global Forecast to 2020" report to ... is expected to reach USD 3,731.03 Million by ... at a CAGR of 11.65% between 2015 and ...
(Date:9/4/2015)... ... September 04, 2015 , ... November Research Group, LLC, ... software tools to pharmaceutical and life sciences organizations, today announced the production implementation ... a mobile data intake solution that enables field sales representatives, clinical research associates, ...
(Date:9/3/2015)... , ... September 03, 2015 , ... ... hamstring tear 18 months ago. Conventional treatment and therapy were not working so ... late June 2015. Dr. McKenna treated Zack with precisely guided injections of bone ...
(Date:9/3/2015)... , Sept. 3, 2015  Vermillion, Inc. (NASDAQ: ... disease, today announced that Herbert Fritsche , Ph.D., ... LABS, is the recipient of the 2015 Abbott Award, ... (ISOBM) for outstanding contributions to the field of basic ... on October 5 th in Zakopane, ...
Breaking Biology Technology:Global Biopreservation Market 2015-2020 - Product, Biospecimen, Application and End User Analysis of the $3.73 Billion Industry 2Global Biopreservation Market 2015-2020 - Product, Biospecimen, Application and End User Analysis of the $3.73 Billion Industry 3November Research Group’s PRIMO Mobile Goes Live at Allergan Japan 2UCLA Wide Receiver and Canadian Decathlon Standout Zack Bornstein Bounces Back After Stem Cell Therapy at Riordan-McKenna Institute 2UCLA Wide Receiver and Canadian Decathlon Standout Zack Bornstein Bounces Back After Stem Cell Therapy at Riordan-McKenna Institute 3Vermillion Announces Dr. Herbert Fritsche as Recipient of the 2015 Abbott Award from the International Society of Oncology and Biomarkers 2
... PharmAthene, Inc. (NYSE Amex: PIP ), a ... chemical threats, today announced that company President and ... Valerie Riddle, Vice President and Medical Director, were ... 30-minute documentary training video entitled, "Deadly Pathogen: Exploring ...
... ST. LOUIS and RICHMOND, Calif., Oct. 5 ... BioSciences, Inc. (Nasdaq: SGMO ) today announced ... to include the exclusive rights to develop and ... lines for commercial production of protein pharmaceuticals. ...
... ... free white paper on Organic Electronics that discusses rfid tags, OLED, AM OLED, PM ... ... published a white paper that discusses the current state of the organic electronics (OE) ...
Cached Biology Technology:PharmAthene Executives Featured in Anthrax Pathogen Training Video for U.S. Department of Homeland Security 2PharmAthene Executives Featured in Anthrax Pathogen Training Video for U.S. Department of Homeland Security 3Sigma-Aldrich(R) and Sangamo BioSciences Announce Major Expansion of ZFP Technology License Agreement 2Sigma-Aldrich(R) and Sangamo BioSciences Announce Major Expansion of ZFP Technology License Agreement 3Sigma-Aldrich(R) and Sangamo BioSciences Announce Major Expansion of ZFP Technology License Agreement 4Free Organic Electronics White Paper Discusses Rfid Tags, OLED, AM OLED, PM OLED, Electroluminescence, e-Paper, OE Market Forecast 2
... using PULSin may be superior to transfection ... traditional transfection, with PULSin you can study ... time course of proteins in cells. Likewise, ... information than traditional RNA interference experiments. ...
... innovative reagent for highly efficient transfer of ... cells. Unlike DNA transfection, with PULSin Protein ... timing of exogenous proteins in cells can ... be studied. Real time function blocking ...
Reacti-Bind DNA Coating Solution...
... Solutions has now entered the next frontier ... partnering up with Cellomics, Inc. The drug ... of Beckman Coulter‘s automated solutions systems and ... information at the sub-cellular level. The integration ...
Biology Products: