Navigation Links
Exposure to toxins makes great granddaughters more susceptible to stress
Date:8/25/2014

Scientists have known that toxic effects of substances known as endocrine disrupting chemicals (EDCs), found in both natural and human-made materials, can pass from one generation to the next, but new research shows that females with ancestral exposure to EDC may show especially adverse reactions to stress.

According to a new study by researchers from The University of Texas at Austin and Washington State University, male and female rats are affected differently by ancestral exposure to a common fungicide, vinclozolin. Female rats whose great grandparents were exposed to vinclozolin become much more vulnerable to stress, becoming more anxious and preferring the company of novel females to familiar females. Males who have the same combination of ancestral exposure and stress do not have the same adverse effects.

"These results should concern us all because we have been exposed to endocrine disrupting chemicals for decades and we all go through natural challenges in life," said David Crews, the Ashbel Smith Professor of Zoology and Psychology at The University of Texas at Austin and lead author of the study. "Those challenges are now being perceived differently because of this ancestral exposure to environmental contamination."

The study was published July 22 online in the journal Endocrinology.

Vinclozolin is a fungicide commonly used by farmers to treat fruits and vegetables.

To test the effects of stress on rats, the researchers confined some of them to soft, warm cylinders for six hours a day for three weeks. This was done during adolescence, a developmentally sensitive time of life for rats, just as for humans. Months later, the researchers tested the brain chemistry, brain function, gene expression and behavior of the rats as adults.

They discovered that for female rats, ancestral exposure to vinclozolin alone or stress during the animal's adolescence alone had negligible effects on the rats'
'/>"/>

Contact: Marc Airhart
mairhart@austin.utexas.edu
512-232-1066
University of Texas at Austin
Source:Eurekalert  

Page: 1 2

Related biology news :

1. In-utero methadone, Subutex exposure could alter gene expression, cause severe Neonatal Abstience Syndrome
2. Study: arctic mammals can metabolize some pesticides, limits human exposure
3. Bee foraging chronically impaired by pesticide exposure: Study
4. Study finds association between maternal exposure to agricultural pesticides
5. In utero exposure to antidepressants may influence autism risk
6. GWAS study ties ABCC9 anomalies, sulfonylurea exposure to HS-Aging
7. Short-term environmental enrichment exposure induces maturity of newborn neurons
8. Public exposure leads to an increase in corrections to the scientific record
9. UV exposure found to lower folate levels in young women
10. Gonorrhea infections start from exposure to seminal fluid
11. Fetal exposure to nicotine increases long-term risk of obesity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Exposure to toxins makes great granddaughters more susceptible to stress
(Date:10/15/2014)... SHELTON, Conn. , Oct. 15, 2014 NXT-ID, Inc. ... a biometric authentication company focused on the growing mobile commerce market ... NASDAQ MarketSite in Times Square on Monday October 13 th . ... with CTO David Tunnel and angel investor Mr. ... Gino Pereira , CEO of NXT-ID thanked his investors and employees ...
(Date:10/14/2014)... Cancer Research shows SIRT6—a protein known to ... the development of skin cancers by turning on an ... skin cells. , Previously considered protective, SIRT6 is part ... help regulate genomic stability and prevent some of the ... damage, which can lead to cancer. This study, in ...
(Date:10/14/2014)... has discovered a new kind of stem cell that can ... liver blood vessels, according to a study published today in ... such a cell type contradicts current theory on how organs ... clues to origins of, and future treatment for, liver cancer., ... into a complex being made up of more than 200 ...
Breaking Biology News(10 mins):Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 3
... potatoes for millennia, but there has been great controversy ... the Proceedings of the National Academies of Sciences, a ... the University of Wisconsin-Madison has for the first time ... cultivated potato. , The scientists analyzed DNA markers in ...
... regulatory gene that shows clear evidence of evolution from ... humans might well have depended in part on hyperactivation ... roles in regulating perception, behavior and memory. , They ... distinctive variant in a regulatory segment of the prodynorphin ...
... Inc. today announced that data from its program ... presented at the 45th Annual Interscience Conference on ... The study represents the first demonstration that ... by treatment with Sangamo's proprietary zinc finger DNA-binding ...
Cached Biology News:Finding rewrites the evolutionary history of the origin of potatoes 2Key brain regulatory gene shows evolution in humans 2Key brain regulatory gene shows evolution in humans 3Key brain regulatory gene shows evolution in humans 4Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection 2
(Date:10/19/2014)... October 19, 2014 The Asian Automatic ... Asian with analysis and forecast of revenue. The Automatic ... to around $463.9 million by 2018, at a developing ... through the TOC of the Asian Automatic patient billing ... provided. This also provides a glimpse of the segmentation ...
(Date:10/19/2014)... 2014 The Asian Orthopedic braces and support ... with analysis and forecast of revenue. The Orthopedic braces and ... around $416.5 million by 2018, at a developing CAGR of ... of the Asian Orthopedic braces and support systems market, to ... provides a glimpse of the segmentation of orthopedic braces and ...
(Date:10/18/2014)... The “Human Insulin Market- by ... Premixed), Modern Human Insulin (Rapid Acting, Long Acting, ... Tresiba, Others) - Forecast to 2018” provides a ... opportunities, current market trends, and strategies impacting the ... and forecasts of the revenue and share analysis. ...
(Date:10/18/2014)... The Asian arthroscopic devices report defines ... and forecast of revenue. The arthroscopic devices market in ... 2018, at a CAGR of 6.5% from 2013 to ... arthroscopic devices market, to get an idea of the ... the segmentation of arthroscopic devices market in the same ...
Breaking Biology Technology:The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 2The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 2The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 2Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 3Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 5The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 2The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 3The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 4
... ... study in combination with trastuzumab. , ... Cambridge, MA (PRWEB) April 17, 2010 -- Merrimack Pharmaceuticals, Inc. announced ... candidates in the company’s pipeline of five novel cancer antibodies, at the 101st Annual ...
... soon be prescribing a dose of dark chocolate to ... high blood pressure in their abdomen, according to new ... 2010, the Annual Meeting of the European Association for ... to the Spanish research, eating dark chocolate reduces damage ...
... ... green technology progresses at an unprecedented rate and the demand for ... Water Resources Conference (FWRC) is paramount. This 3-day utility conference, packed ... it’s kind in the Southeast. Planned for May 16 –19, 2010 ...
Cached Biology Technology:Merrimack to Present Pre-Clinical Data on MM-121 and MM-111 at the 101st Annual Meeting of American Association for Cancer Research (AACR) 2Merrimack to Present Pre-Clinical Data on MM-121 and MM-111 at the 101st Annual Meeting of American Association for Cancer Research (AACR) 3Study shows potential benefit of dark chocolate for liver disease patients 2Florida Water Resources Annual Conference Focuses on Numeric Nutrient and Other Water Issues 2Florida Water Resources Annual Conference Focuses on Numeric Nutrient and Other Water Issues 3
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)...
... Removal of excess dye terminators, template ... from the true sequencing products have proved ... This product is designed to work with ... BigDyeTM and DYEnamicTM ET. The unique uniformity ...
Mature rat whole blood (Sprague-Dawley, averaging 7-8 weeks of age, either sex) is collected at the time of slaughter and processed within 45 minutes. It is then filtered through gauze, pooled in an ...
X-gal,1g...
Biology Products: