Navigation Links
Exposure to low doses of BPA alters gene expression in the fetal mouse ovary
Date:8/24/2010

A study posted today (Wednesday, August 25) at the online site of the journal Biology of Reproduction reports that exposure of pregnant female mice to the endocrine-disrupting chemical bisphenol A may produce adverse reproductive consequences on gene expression in fetal ovaries as early as 12 hours after the mother has first been exposed to the chemical.

Bisphenol A (BPA) is a chemical used in plastics for making some baby and water bottles, linings of food and beverage cans, and other human consumer products.

The mice in this study were given BPA at doses thought to be equivalent to levels currently being experienced by humans.

The research, conducted in the laboratory of Dr. Patricia A. Hunt at Washington State University (WSU) in Pullman, showed that BPA exposure affects the earliest stages of egg production in the ovaries of the developing mouse fetuses, thus suggesting that the next generation (the grandchildren of the females given BPA) may suffer genetic defects in such biological processes as mitosis and DNA replication.

In addition, the WSU research team noted that their study "revealed a striking down-regulation of mitotic/cell cycle genes, raising the possibility that BPA exposure immediately before meiotic entry might act to shorten the reproductive lifespan of the female" by reducing the total pool of fetal oocytes.

Future studies in Dr. Hunt's laboratory will focus on genetic changes produced over a range of BPA exposure.


'/>"/>

Contact: Patricia A. Hunt
pathunt@wsu.edu
509-335-4954
Society for the Study of Reproduction
Source:Eurekalert

Page: 1

Related biology news :

1. Study: Bird diversity lessens human exposure to West Nile Virus
2. Birth control has long-term effect on hormone exposure
3. Major source of radon exposure overlooked at former Ohio uranium-processing plant
4. Household exposure to toxic chemicals lurks unrecognized, researchers find
5. Study reveals effects of unconscious exposure to advertisements
6. Benefits of breastfeeding outweigh risk of infant exposure to environmental chemicals in breastmilk
7. Novel technique changes lymph node biopsy, reduces radiaiton exposure
8. Novel technique changes lymph node biopsy, reduces radiation exposure
9. Swimmers at public beaches show increased risk of exposure to contagious staph bacteria
10. How increased UV exposure impacts plants
11. Exposure to insecticide may play role in obesity epidemic among some women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/10/2015)... , August 10, 2015 The latest ... offers comprehensive analysis of the global border security market ... revenues of $16.4bn in 2015. Now: Border security ... an example of the business critical issue you need to ... visiongain ,s objective analysis of how this will impact ...
(Date:8/6/2015)... , Aug. 6, 2015 Synaptics Inc. ... human interface solutions, today announced collaboration with Microsoft ... Windows 10. Microsoft leveraged Synaptics, deep expertise in ... system. Through stringent testing, Synaptics, ... certified with Microsoft,s Precision TouchPad (PTP) specification empowering ...
(Date:8/5/2015)... 2015 The biosensors market is proving highly ... into newer sectors, and development of devices resulting in ... has seen the entry of multiple participants each year ... (Photo - http://photos.prnewswire.com/prnh/20150805/255570 ) ... the Global Biosensors Market ( http://www.frost.com/nee9 ), finds ...
Breaking Biology News(10 mins):Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9Synaptics Chosen for Human Interface Co-Development on Windows 10 2Innovative Biosensors Incite Use in Non-Traditional Applications 2Innovative Biosensors Incite Use in Non-Traditional Applications 3Innovative Biosensors Incite Use in Non-Traditional Applications 4
... Inc.,(OTC Bulletin Board: INVI), a leading global supplier ... received an order for the,Company,s SharpEye(TM) system from ... manufacturer. The SharpEye product provides analysis of functional,and ... in the manufacturing,process, and the system will be ...
... produced to help people absorb more calcium. Researchers ... the calcium intake of humans who ate the carrot and ... was done in collaboration with Baylor College of Medicine, means ... diseases as osteoporosis. If you eat a serving ...
... some of the genetic secrets that enable pine ... disease, uncovering critical new information about forests natural ... this genetic analysis will allow forest stewardship programs ... that could in time repel insects such as ...
Cached Biology News:Integral Vision, Inc. Announces SharpEye(TM) Order From New Customer 2Got carrots? Vegetables may have bone to pick as calcium providers 2UBC discovery unlocks tree genetics, gives new hope for pine beetle defense 2
(Date:8/27/2015)... ... 27, 2015 , ... Capital Edge Consulting , a nationwide consulting firm ... announce their ranking as one of the top 5000 companies listed on the ... the nation. , “It is truly an honor to be recognized as one of ...
(Date:8/27/2015)... /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") today ... 30, 2015. Biorem,s complete second quarter financial statements and MD&A have ... ,000,s except earnings per shareThree-months ended , Six -months endedJune 30 ... 2015 , 2014 Revenue , 4,709 , ... profit , 1,656 , 56 , ...
(Date:8/27/2015)... N.C. , Aug. 27, 2015 ... decision by FedEx, UPS and The US Postal ... biological specimens classified as ,select agents, by the ... history of handling these sensitive shipments. ... global transportation regulations, trained and certified personnel to ...
(Date:8/26/2015)... ... August 26, 2015 , ... ... its investment in the development and manufacture of highly valued cardiac markers used ... scientific team's extensive expertise with protein chemistry has led to the development and ...
Breaking Biology Technology:Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 2Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 3BIOREM Reports $718,000 Net Earnings for the Second Quarter 2BIOREM Reports $718,000 Net Earnings for the Second Quarter 3Marken Ensures Safe Transportation Of Select Agents And Toxins 2Lee Biosolutions Announces Increased Investment in the Development and Manufacturing of Biomarkers Used in Early Detection Of Heart Disease 2
... , NEW BRUNSWICK, N.J., Nov. 16 Senesco Technologies, ... today announced that, on November 16, 2009, Bruce C. Galton ... of directors. In addition, Mr. Galton resigned from his ... pursue other interests. Mr. Galton and the Company currently ...
... , ARMSTRONG, Iowa, Nov. 16 Art,s Way Manufacturing, ... Art,s Way Scientific, Inc. - Buildings For Science - will ... nursery and finisher operations. The complex will be used to ... production. Research projects will include trials on nutrition, physiology and ...
... 16 Palatin Technologies, Inc. (NYSE Amex: PTN ) today ... reported a net loss of $37,000, or $(0.00) per basic and ... a net loss of $4.3 million, or $(0.05) per basic and ... in the quarter ended September 30, 2009 were $3.7 million, compared ...
Cached Biology Technology:Senesco Technologies, Inc. Announces Management Change 2Senesco Technologies, Inc. Announces Management Change 3Art's Way Manufacturing Announces Contract for Modular Swine Facility for the University of Georgia 2Art's Way Manufacturing Announces Contract for Modular Swine Facility for the University of Georgia 3Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on November 16, 2009 2Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on November 16, 2009 3Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on November 16, 2009 4Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on November 16, 2009 5Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on November 16, 2009 6
Mycoplasma tested...
...
... kit contains the basic components required for ... natural and recombinant rat Thymus Chemokine-1 in ... contains sufficient materials to run ELISAs on ... following conditions are met: The ...
Blimp-1 (H-150)...
Biology Products: