Navigation Links
Evolution can select for evolvability, Penn biologists find
Date:11/14/2013

Evolution does not operate with a goal in mind; it does not have foresight. But organisms that have a greater capacity to evolve may fare better in rapidly changing environments. This raises the question: does evolution favor characteristics that increase a species' ability to evolve?

For several years, biologists have attempted to provide evidence that natural selection has acted on evolvability. Now a new paper by University of Pennsylvania researchers offers, for the first time, clear evidence that the answer is yes.

The senior author on the study, published in the journal PLOS Pathogens, is Dustin Brisson, an assistant professor in the School of Arts and Sciences' Department of Biology. His coauthors include Penn's Christopher J. Graves, Vera I. D. Ros and Paul D. Sniegowski, and the University of Kentucky's Brian Stevenson.

"It's not controversial that populations evolve and that some traits are more apt to evolve than others," Brisson said. "What we were asking is whether the ability of an organism to evolve is a trait that natural selection can pick."

For species of viruses, pathogenic bacteria and parasites to survive over the long-term, they must possess an ability to rapidly adapt and evolve, enabling them to stay one step ahead of their hosts' immune systems. But these pathogens don't need to foresee what conditions lie ahead of them. They only must change into something that the immune system has never seen before.

"Pathogens face a very strong selection pressure from the host's immune system," Brisson said. "If they don't adapt, they will die."

The researchers used this fact to seek evidence that natural selection had favored increased evolvability, focusing on the Lyme disease bacteria, Borrelia burgdorferi.

B. burgdorferi possesses one protein that is essential for establishing a long-term infection of a mammalian host: VlsE.

In the Lyme bacteria's genome, th
'/>"/>

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Penn team elucidates evolution of bitter taste sensitivity
2. Fast-mutating DNA sequences shape early development; guided evolution of uniquely human traits
3. Targeting evolution: Could this be the next strategy to stop superbugs?
4. Alfred Russel Wallace: Co-founder of the theory of biological evolution
5. Climate change and coevolution: Weve done the math
6. Grazers and pollinators shape plant evolution
7. Evolutionary medicine of skin cancer risk among Europeans
8. Recent highlights in Molecular Biology and Evolution
9. Fear of holes may stem from evolutionary survival response
10. Penn biologists show that generosity leads to evolutionary success
11. Biometrics Can Revolutionise Mobile Payment Security, says Frost & Sullivan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)...  A man-made form of insulin delivered by nasal spray ... adults with mild cognitive impairment and Alzheimer,s disease dementia, ... Wake Forest Baptist Medical Center. The study,s ... impairment (MCI) or mild to moderate Alzheimer,s dementia (AD). ...
(Date:1/22/2015)... YORK , Jan. 21, 2015  Analyst Report Issued by ... Card Brands report showed that planet-wide, transactions at merchants on ... while the total number of credit, debit, and prepaid cards ... U.S. were victims of fraudulent card usage in 2012, and ...
(Date:1/22/2015)... , Jan. 22, 2015   EyeLock, Inc. , a market ... appointed Steve Gerber to the new role of ... responsible for leading development of mobile platforms and wearable solutions ... success and innovation in the semiconductor industry to his role ...
Breaking Biology News(10 mins):Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... team led by Professor Tadashi ISA, Project Assistant ... Physiological Sciences, The National Institutes of Natural Sciences ... "the double viral vector transfection technique" which can ... combining two new kinds of gene transfer vectors. ...
... ,SALT LAKE CITY, June 14, 2012 In Israel,s Negev ... a toxic "mustard oil bomb" to make the spiny mouse ... the plant has turned a seed-eating rodent into a seed ... by Utah and Israeli scientists. "It,s fascinating that these ...
... International Olympic Committee (IOC) Medical and Scientific Department has ... Centre as an international leader in researching and preventing ... in the Faculty of Kinesiology, will be named one ... sites at a special reception to be held on ...
Cached Biology News:Manipulation of a specific neural circuit buried in complicated brain networks in primates 2Ptooey! 2Ptooey! 3Ptooey! 4IOC recognizes University of Calgary Sports Injury Research Prevention Centre 2
(Date:2/27/2015)... , Feb. 27, 2015   PureTech , a ... and commercializing disruptive products and technologies in the healthcare ... , former CEO and Member of the Board of ... "It,s has been a pleasure to know ... that we will be working together more closely now," ...
(Date:2/26/2015)... , Feb. 26, 2015 /PRNewswire/ - SQI Diagnostics ... a life sciences company that develops and commercializes proprietary ... its financial and operational results for the fiscal first ... press release are in Canadian dollars (CAD), unless otherwise ... continued to win new business from our existing customers ...
(Date:2/26/2015)... 26, 2015 DuPont Executive Vice President ... key research advancements and product launches across the Agriculture ... America Merrill Lynch 2015 Global Agriculture Conference. ... grain supplies the last two years, long-term demand for ... of the last decade, when demand for corn and ...
(Date:2/26/2015)... The healthcare landscape is rapidly and radically changing. ... will host its 20 th Anniversary Medical Technologies ... to 10, at the Hilton San Diego Resort and Spa ... This event is a platform for global medical devices, diagnostics, ... and how to succeed in an uncertain future. ...
Breaking Biology Technology:Christopher Viehbacher, former CEO of Sanofi, Joins PureTech's Board of Directors 2Christopher Viehbacher, former CEO of Sanofi, Joins PureTech's Board of Directors 3Christopher Viehbacher, former CEO of Sanofi, Joins PureTech's Board of Directors 4SQI Diagnostics Reports First Quarter Financial Results 2SQI Diagnostics Reports First Quarter Financial Results 3SQI Diagnostics Reports First Quarter Financial Results 4SQI Diagnostics Reports First Quarter Financial Results 5SQI Diagnostics Reports First Quarter Financial Results 6DuPont Leader Outlines Path for Growth in Agriculture and Nutrition & Health Segments 2DuPont Leader Outlines Path for Growth in Agriculture and Nutrition & Health Segments 3DuPont Leader Outlines Path for Growth in Agriculture and Nutrition & Health Segments 4DuPont Leader Outlines Path for Growth in Agriculture and Nutrition & Health Segments 5Embrace the Future of Medical Technologies with Frost & Sullivan 2Embrace the Future of Medical Technologies with Frost & Sullivan 3
... Sept. 17 MannKind Corporation,(Nasdaq: MNKD ) today ... and Drug Administration to use AFRESA as the trade ... was unveiled today by Alfred Mann,Chairman and Chief Executive ... Conn., location that marked the completion and,dedication of a ...
... Professor And Former Chair Of Psychology Department At Harvard University,Joins ... Leading ... Neurological Testing Company, BERKELEY, Calif., Sept. 17 ... neurological testing for marketing,research, announced that professor Stephen Kosslyn, Ph.D. ...
... based upon Gov. Deval ... Life Sciences Initiative -, LEXINGTON, Mass., Sept. ... Dedication of its new HQ/manufacturing facility, -- WHEN: ... -- WHERE: 44 Hartwell Avenue, Lexington, Mass., RainDance Technologies, ...
Cached Biology Technology:MannKind Unveils Proposed Trade Name at Dedication of Danbury Manufacturing Facility 2MannKind Unveils Proposed Trade Name at Dedication of Danbury Manufacturing Facility 3Neurofocus Appoints Stephen Kosslyn to Its Advisory Board 2RainDance Technologies to Dedicate New Headquarters, Manufacturing Facility in Lexington 2
One-step, colorimetric, linear detection range 0.7 mg/dL to 300 mg/dL. Procedure: 10 min....
XBP1 Antibody...
... to histochemically detect specific ... pH in cultured cells ... specific marker is only ... (not found in presenescent/quiescent/immortal ...
Human/Mouse/Rat JNK Pan Specific Affinity Purified PAb...
Biology Products: