Navigation Links
Evolution can select for evolvability, Penn biologists find
Date:11/14/2013

Evolution does not operate with a goal in mind; it does not have foresight. But organisms that have a greater capacity to evolve may fare better in rapidly changing environments. This raises the question: does evolution favor characteristics that increase a species' ability to evolve?

For several years, biologists have attempted to provide evidence that natural selection has acted on evolvability. Now a new paper by University of Pennsylvania researchers offers, for the first time, clear evidence that the answer is yes.

The senior author on the study, published in the journal PLOS Pathogens, is Dustin Brisson, an assistant professor in the School of Arts and Sciences' Department of Biology. His coauthors include Penn's Christopher J. Graves, Vera I. D. Ros and Paul D. Sniegowski, and the University of Kentucky's Brian Stevenson.

"It's not controversial that populations evolve and that some traits are more apt to evolve than others," Brisson said. "What we were asking is whether the ability of an organism to evolve is a trait that natural selection can pick."

For species of viruses, pathogenic bacteria and parasites to survive over the long-term, they must possess an ability to rapidly adapt and evolve, enabling them to stay one step ahead of their hosts' immune systems. But these pathogens don't need to foresee what conditions lie ahead of them. They only must change into something that the immune system has never seen before.

"Pathogens face a very strong selection pressure from the host's immune system," Brisson said. "If they don't adapt, they will die."

The researchers used this fact to seek evidence that natural selection had favored increased evolvability, focusing on the Lyme disease bacteria, Borrelia burgdorferi.

B. burgdorferi possesses one protein that is essential for establishing a long-term infection of a mammalian host: VlsE.

In the Lyme bacteria's genome, th
'/>"/>

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Penn team elucidates evolution of bitter taste sensitivity
2. Fast-mutating DNA sequences shape early development; guided evolution of uniquely human traits
3. Targeting evolution: Could this be the next strategy to stop superbugs?
4. Alfred Russel Wallace: Co-founder of the theory of biological evolution
5. Climate change and coevolution: Weve done the math
6. Grazers and pollinators shape plant evolution
7. Evolutionary medicine of skin cancer risk among Europeans
8. Recent highlights in Molecular Biology and Evolution
9. Fear of holes may stem from evolutionary survival response
10. Penn biologists show that generosity leads to evolutionary success
11. Biometrics Can Revolutionise Mobile Payment Security, says Frost & Sullivan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/5/2015)... 5, 2015 Transparency Market Research ... Market - Global Industry Analysis, Size, Share, Growth, Trends ... facial recognition is forecast to reach US$ 2,671.8 Mn ... for surveillance systems by civil and government agencies. This ... and terrorist activities across the globe that would elevate ...
(Date:8/4/2015)... 2015 Research ... the addition of the "Digital Forensics ... Sub-Segment (Computer Forensics, Network Forensics, Mobile Device ... Vertical and Region - Global Forecast to ... By Component (Hardware, Software, and Service), ...
(Date:8/3/2015)... , Aug. 3, 2015 Synaptics, Inc. ... interface solutions, today announced that members of the executive ... the Pacific Crest Global Technology Leadership Forum on Tuesday, ... conference will be held at the Sonnenalp Resort in ... The presentation may include forward-looking information. An audio webcast ...
Breaking Biology News(10 mins):Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2
... water could provide an early indicator of climate change. ... could forewarn of climate change in 10 to 20 ... Science Foundation (ESF) conference, scientists predicted that the waters ... New Zealand are the places to watch. , Palaeoclimate ...
... different gene mutations, but just how these mutations contribute to ... new clue comes from scientists at the University of North ... Their research indicates that early life sun exposure, from birth ... melanomas with BRAF gene mutations. A different mutation, on the ...
... to be living with Alzheimer’s disease in 2006, according to ... School of Public Health. The researchers also concluded the global ... million by 2050. By that time, 43 percent of those ... of a nursing home. The findings were presented June 10 ...
Cached Biology News:Salty oceans provide early warning for climate change 2Sun exposure early in life linked to specific skin cancer gene mutation 2Alzheimer's disease to quadruple worldwide by 2050 2
(Date:9/2/2015)... CHARLOTTESVILLE, Virginia , September 2, 2015 /PRNewswire/ ... Sponsoring der Gewinner des Wettbewerbs BeHEARD von 2015 ... einen internationalen vom Rare Genomics Institute. ... Wirksamkeit von Medikamenten für die Behandlung anderer Krankheiten ... wurde, Steven Laffoon und sein Team ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... to creating professional commercial video content, to analysis of athletic performance. Producing ... that go by too quickly to process with the naked eye. , ...
(Date:9/1/2015)... The American Brain Tumor Association (ABTA) is now accepting ... program. LOIs are due no later than Wednesday, October ... Discovery Grants are one-year, $50,000 grants that fund high risk/high ... or treatment paradigms for adults and children with brain ... earliest stages, in the hopes that it spurs additional ...
(Date:9/1/2015)... ... September 01, 2015 , ... In her thought provoking debut novel ‘ Ebola ... not-so-distant future faced with an Ebola pandemic that is on the cusp of wiping ... enter the world of counterterrorism, and who continues to appear in this series of ...
Breaking Biology Technology:Biovista sponsert die Forschung von Wylder Nation Foundation zum Thema Mangel an saurer Sphingomyelinase 2Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 2Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 3American Brain Tumor Association Seeks Innovative Concepts For Discovery Research Grants 2Alexi Venice’s Debut Novel Takes on the Human Testing of a Vaccine for Ebola and Revenge by an Anti-Big Pharma Terrorist Group in ‘Ebola Vaccine Wars' 2Alexi Venice’s Debut Novel Takes on the Human Testing of a Vaccine for Ebola and Revenge by an Anti-Big Pharma Terrorist Group in ‘Ebola Vaccine Wars' 3
... Calif. and MONROVIA, Calif., Jan. 6, 2011 Amgen ... today that they will collaborate to develop XmAb ® ... and CD32b.  XmAb5871 is currently in late-stage preclinical development ... Under the terms of the agreement, Amgen has the ...
... SAN FRANCISCO, Jan. 6, 2011 Vista Partners ... Therapeutics, Inc. (Nasdaq: OPXA ) and raised ... Silver, Principal Analyst at Vista Partners stated, "Opexa announced yesterday ... for the treatment of Multiple sclerosis , is now ...
... 6, 2011 BioInformatics, LLC announces the release of ... Technologies:  Market Insights for Life Science Suppliers (#10-005) This ... respond in a timely fashion to the rapidly changing ... LLC quantifies and characterizes the market for genetic analysis ...
Cached Biology Technology:Amgen and Xencor Enter Option Deal to Co-Develop Xencor's Novel Antibody for Autoimmune Diseases 2Amgen and Xencor Enter Option Deal to Co-Develop Xencor's Novel Antibody for Autoimmune Diseases 3Vista Partners Updates Coverage on Opexa Therapeutics, Inc.; Raises Target Price From $4.40 to $6.50 2BioInformatics, LLC New Market Report - Genomics Technologies 2