Navigation Links
European Society of Human Genetics urges caution over use of new genetic sequencing techniques
Date:5/16/2013

The use of genome-wide analysis (GWA), where the entirety of an individual's DNA is examined to look for the genomic mutations or variants which can cause health problems is a massively useful technology for diagnosing disease. However, it can also pose major ethical problems if used incorrectly, say new recommendations from the European Society of Human Genetics (ESHG) published on line today (16 May 2013) in the European Journal of Human Genetics.

Many services based on whole genome and on exome* sequencing and analysis are now available to patients at an affordable price, and this raises the question of how to ensure that they are provided appropriately. "Such sequencing generates huge amounts of information that needs to be processed, analysed, and stored in a responsible manner", said Professor Martina Cornel, chair of the Professional and Public Policy Committee of ESHG. "It is preferable to use sequencing or analysis specifically targeted at a particular health problem to avoid unsolicited findings, or those that cannot yet be interpreted, which can cause considerable anxiety to patients and their families. Clear guidance on how to deal with such findings is needed."

Targeted analysis will limit such unsolicited findings, says the ESHG, and this is particularly important at present when there are only a limited number of clinicians properly trained to inform patients on the significance of the results of GWAs and exome sequencing. While the Society believes that the duty to inform patients may outweigh their right not to know in some circumstances, the new recommendations propose that analysis should be limited to genome regions linked to the clinical problem for which the analysis is being undertaken.

"We are opposed to the type of opportunistic screening that throws up large numbers of incidental results. If such results reveal a treatable or preventable condition, then clearly it is advantageous to patients to be informed ab
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
European Society of Human Genetics
Source:Eurekalert

Page: 1 2

Related biology news :

1. Core for Life, a new European alliance in biomedical research
2. European support for the first network of research and training in political ecology
3. 8 M € from EU to enhance access by scientists to the largest European biobanks
4. Scientists awarded £3M to study the way Northwest European seas absorb carbon
5. European Guidance for the diagnosis & management of osteoporosis in postmenopausal women
6. Can a tropical water flea invade European lakes?
7. Less than 1 month to start of European Congress on Osteoporosis & Osteoarthritis in Rome
8. A European invader outcompetes Canadian plants even outside its usual temperature range
9. Felix Goñi, Avanti award for best European research in lipids
10. 2013 General Assembly of the European Geosciences Union
11. REACH news: European ombudsman takes up PETA complaint
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2015)... Calif. , March 2, 2015 ... leading developer of human interface solutions, today announced ... that is designed to enable rapid and secure ... ID™ module for gaming is a turnkey solution ... the ability to quickly integrate fingerprint ID solutions ...
(Date:3/2/2015)... , March 2, 2015   Neurotechnology , ... today introduced the SentiGaze Software Development Kit ... create applications that use off-the-shelf webcams to track eye ... gazes at a monitor. Heatmaps can be used for ... effectiveness of online advertising. The SDK can also be ...
(Date:2/24/2015)... , Feb. 24, 2015 This report analyzes ... report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... . Annual estimates and forecasts are provided for the period ... for these markets. Market data and analytics are derived from ...
Breaking Biology News(10 mins):Synaptics Unveils New Fingerprint ID Solution for Gamers 2Synaptics Unveils New Fingerprint ID Solution for Gamers 3Neurotechnology Releases SentiGaze SDK for Eye Movement Tracking Using Ordinary Webcams 2Neurotechnology Releases SentiGaze SDK for Eye Movement Tracking Using Ordinary Webcams 3World Iris Biometrics Industry 2World Iris Biometrics Industry 3World Iris Biometrics Industry 4World Iris Biometrics Industry 5World Iris Biometrics Industry 6World Iris Biometrics Industry 7World Iris Biometrics Industry 8World Iris Biometrics Industry 9World Iris Biometrics Industry 10World Iris Biometrics Industry 11
... range found surviving members of a species of Harlequin ... out amphibian populations in Central and South America. , ... of the painted frog (Atelopus ebenoides marinkellei) indicates the ... species also might avoid elimination from the epidemic caused ...
... Analytical Chemistry, scientists at Indiana University Bloomington report ... follow the weakest of scents. Even when ovary ... still found their mark. , A video demonstrating ... chemical gradient) can be downloaded at http://www.iuinfo.indiana.edu/bem/media_relations/movie.chemotaxis.mpg ...
... the brain creates a scent symphony from signals sent by ... that nerve cells in the brain's olfactory bulb -- the ... perceive complex scent mixtures as single objects, such as the ... neurons, detect the host of chemical compounds that comprise a ...
Cached Biology News:Colombian frog believed extinct found alive 2Even when faint, ovary scent draws sperm cells 2Researchers show how brain decodes complex smells 2
(Date:3/5/2015)... March 05, 2015 Bi-Biomics today ... paraffin and stain additive. The improvement in histological ... binary features present in all daughter cells. , ... chromatin packaging was analyzed at 1000-1600x using light ... chromatin patterning in all daughter cells displayed predominant ...
(Date:3/5/2015)... and TORONTO , March ... APS), a clinical-stage company developing new therapeutics and molecular ... announced that William G. Rice , Ph.D., Chairman, ... upcoming 27th Annual ROTH Conference on Tuesday, March 10 ... Ritz Carlton, Laguna Niguel, CA. ...
(Date:3/5/2015)... Research and Markets ( http://www.researchandmarkets.com/research/4ld5nw/mature_biotech ) ... Outlook 2015: New Therapy Ventures Pave the Way for ... All biotech companies - Gilead (GILD), Amgen (AMGN), Biogen ... given a positive return and hence increased the interest ... select therapy/niche indication where the high treatment cost justifies ...
(Date:3/5/2015)... Ohio (PRWEB) March 05, 2015 ... Gold Development Partner located in Northeast Ohio, today announced ... e2b teknologies to support its upgrade to the latest ... the largest independent group practice of its kind in ... and large volume of transactions, so efficiency and data ...
Breaking Biology Technology:Aptose Biosciences to Present at the 27th Annual ROTH Conference 2Aptose Biosciences to Present at the 27th Annual ROTH Conference 3Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 2Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 3Physician Group Practice Chooses e2b teknologies to Support Its Upgrade to Sage 100 ERP 2014 2
... of the Personal Genome Project and Matthew Trunnell of The Broad ... of Life Sciences ResearchSEATTLE, April 24 Isilon(R) Systems ... scale-out NAS, today announced a unique gathering of industry leaders from ... and Expo 2009 in Boston, Mass. Dr. George Church, ...
... April 24 United Therapeutics Corporation (Nasdaq: ... 2009 first quarter financial results before market open on ... teleconference on Friday, May 1, 2009, at 9:00 a.m. ... 877-718-5092, with international callers dialing 719-325-4795. A rebroadcast ...
... - Strong Product Offerings and ... Nucletron, a global leader in radiation oncology, ... of EUR112.4 million (US $165,million). EBITDA in 2008 ended ... million with a strong fourth quarter contributing significantly to,the ...
Cached Biology Technology:Isilon Hosts Industry Leaders Panel on the Future of Life Sciences and IT at Bio-IT World 2009 2Isilon Hosts Industry Leaders Panel on the Future of Life Sciences and IT at Bio-IT World 2009 3Nucletron Announces 2008 Results 2
... 5'GCCNNNN NGGC3' 3'CGGN NNNNCCG5' Inactivation Conditions: Heat ... phenol treatment followed by ethanol precipitation. Storage ... 0.1mM EDTA, 1.0mM DTT, 0.01% BSA, 50% ... ice. Store at -20C. Unit Definition: One ...
... stainless-steel shaker flask clips, purpose-designed to firmly ... All clips are equipped with a top ... include a bottom retainer spring, and silicon ... expensive glassware. Clips include the required ...
... Red Taq DNA Polymerase is a thermostable ... activity in primer extension and other molecular ... dye which provides easy and quick identification ... and allows confirmation of complete mixing. The ...
... on measurenment of enzyme activity of TRAP ... plate. The procedure includes two incubation steps ... enzyme reaction) separated by a washing ... determination of human enzymaticaly active TRAP 5 ...
Biology Products: