Navigation Links
Epigenetics shapes fate of brain vs. brawn castes in carpenter ants
Date:2/13/2013

dual, so we asked whether there are also overall differences in histone modifications between the brawny majors and the brainy minors that might alter specific features of the whole organism, such as behavior."

In examining several different histone modifications, the team found a number of distinct differences between the major and minor castes. Simola states that the most notable modification, "both discriminates the two castes from each other and correlates well with the expression levels of different genes between the castes. And if you look at which genes are being expressed between these two castes, these genes correspond very nicely to the brainy versus brawny idea. In the majors we find that genes that are involved in muscle development are expressed at a higher level, whereas in the minors, many genes involved in brain development and neurotransmission are expressed at a higher level."

These changes in histone modifications between ant castes are likely caused by a regulator gene, called CBP, that has "already been implicated in aspects of learning and behavior by genetic studies in mice and in certain human diseases," Berger says. "The idea is that the same CBP regulator and histone modification are involved in a learned behavior in ants foraging mainly in the brainy minor caste, to establish a pattern of gene regulation that leads to neuronal patterning for figuring out where food is and being able to bring the food back to the nest."

Simola notes that "we know from mouse studies that if you inactivate or delete the CBP regulator, it actually leads to significant learning deficits in addition to craniofacial muscular malformations. So from mammalian studies, it's clear this is an important protein involved in learning and memory."

These findings have established the crucial role of genome structure in general, and histone modifications in particular, in determining the acquisition of organism-level characteristics i
'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Study finds epigenetics, not genetics, underlies homosexuality
2. Sick from stress? Blame your mom… and epigenetics
3. Not by DNA alone: How the epigenetics revolution is fostering new medicines
4. Epigenetics and epidemiology -- hip, hype and science
5. New geometries: Researchers create new shapes of artificial microcompartments
6. Oh, my stars and hexagons! DNA code shapes gold nanoparticles
7. Not a 1-way street: Evolution shapes environment of Connecticut lakes
8. Early music lessons boost brain development
9. Human brain is divided on fear and panic
10. Propping open the door to the blood brain barrier
11. Leadership Chair to champion tech devices for brain trauma, disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Epigenetics shapes fate of brain vs. brawn castes in carpenter ants
(Date:6/18/2015)... , June 18, 2015 NXT-ID, Inc. (NASDAQ: ... focused on the growing mobile commerce market announces that its ... segment on "Money on the Mark", scheduled to air on ... June 20 th . The broadcast ... from 7:00 to 8:00pm EST. NXT-ID, Inc.,s CEO Gino ...
(Date:6/16/2015)... , June 16, 2015 /CNW Telbec/ - ... partnership centralized around the incorporation of handyem,s HPC-150 ... diagnostic laboratory, the Mo-POD™. This unprecedented model of ... International Conference at the Pennsylvania ... from June 15 th to 18 th ...
(Date:6/15/2015)... A new report [ 1 ... of US consumers using mobile banking applications want their mobile ... and voiceprint, instead of having to prove who they are ... Mobile Identity   -   The Fusion of Financial Services, ... the primary channel used by Gen X and Gen Y ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 2NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 3handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 2handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 3One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 2One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 3One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 4
... consumption in birds and mammals was limited by resource levels, ... while food was plentiful and produce as many offspring as ... shown that, even when food is abundant, energy intake reaches ... as lactating females. Scientists at the Research Institute of Wildlife ...
... familiar with the fact that cognitive function declines as we ... kind of daily activities we engage in during the course ... decline. A team of researchers from Technische Universitt Berlin are ... learning performance as they age. Surprisingly, they have found that, ...
... halo surrounding highly-publicized marketing campaigns regarding sweetener reformulations ... Starbucks and other brands that they will remove ... being called into question in news articles by ... have poked holes in companies, marketing efforts and ...
Cached Biology News:Key to evolutionary fitness: Cut the calories 2A young brain for an old bee 2Recent news reports of sweetener reformulations raise questions about motivations 2
(Date:7/1/2015)... , ... July 01, 2015 , ... It is now ... (TBI) using single photon emission computed tomography (SPECT) according to researchers from ... which examined over 20,000 brain scans and is believed to be the largest brain ...
(Date:7/1/2015)... ... ... The next-generation sequencing (NGS) clinical market is poised for huge growth as it prepares ... in its new report that the market drivers of this vibrant industry include increased ... diagnostics as part of a molecular diagnostics trend. , The global market is forecast ...
(Date:7/1/2015)... , July 1, 2015  Axovant Sciences Ltd. ... on the treatment of dementia, today announced that ... July 22 at 5:45 p.m. EDT following its ... Association International Conference 2015 (AAIC). ... , Dr. Lawrence Friedhoff , Chief ...
(Date:7/1/2015)... InferMed , s ... will augment ... s olutions suite   Elsevier , ... and services, announced today the acquisition of  InferMed , a ... company. InferMed,s Arezzo technology supports clinicians in choosing ...
Breaking Biology Technology:Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 2Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 3Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 4NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 3Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 2Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 2Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 4
... to the Menomonee Valley, Gov. Jim Doyle announced ... budget for the new Wisconsin Venture Center. , ,Doyle said ... will connect entrepreneurs with sources of capital, and serve as ... Wisconsin. , ,The concept was announced in December of 2006 ...
... and investors who are trying to come up with the ... relocate here have a fight on their hands. , ,And ... of Aruna Biomedical , an Athens, Ga. business that ... to move from research to production. , ,Last week, the ...
... has served as vice president of Quintessence Biosciences ... and chief operating officer of the Madison-based biopharmaceutical company. ... board of directors and announced at the company's annual ... from the University of Wisconsin-Madison , brings a ...
Cached Biology Technology:Doyle proposes $2M for venture capital center 2Wisconsin won't get Georgia biotech without a fight 2Wisconsin won't get Georgia biotech without a fight 3
...
... Custom Synthesis Service provides you ... to knockdown any gene. We ... base pairs with terminal dT ... other lengths of your choice. ...
...
...
Biology Products: