Navigation Links
Epigenetics shapes fate of brain vs. brawn castes in carpenter ants
Date:2/13/2013

dual, so we asked whether there are also overall differences in histone modifications between the brawny majors and the brainy minors that might alter specific features of the whole organism, such as behavior."

In examining several different histone modifications, the team found a number of distinct differences between the major and minor castes. Simola states that the most notable modification, "both discriminates the two castes from each other and correlates well with the expression levels of different genes between the castes. And if you look at which genes are being expressed between these two castes, these genes correspond very nicely to the brainy versus brawny idea. In the majors we find that genes that are involved in muscle development are expressed at a higher level, whereas in the minors, many genes involved in brain development and neurotransmission are expressed at a higher level."

These changes in histone modifications between ant castes are likely caused by a regulator gene, called CBP, that has "already been implicated in aspects of learning and behavior by genetic studies in mice and in certain human diseases," Berger says. "The idea is that the same CBP regulator and histone modification are involved in a learned behavior in ants foraging mainly in the brainy minor caste, to establish a pattern of gene regulation that leads to neuronal patterning for figuring out where food is and being able to bring the food back to the nest."

Simola notes that "we know from mouse studies that if you inactivate or delete the CBP regulator, it actually leads to significant learning deficits in addition to craniofacial muscular malformations. So from mammalian studies, it's clear this is an important protein involved in learning and memory."

These findings have established the crucial role of genome structure in general, and histone modifications in particular, in determining the acquisition of organism-level characteristics i
'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Study finds epigenetics, not genetics, underlies homosexuality
2. Sick from stress? Blame your mom… and epigenetics
3. Not by DNA alone: How the epigenetics revolution is fostering new medicines
4. Epigenetics and epidemiology -- hip, hype and science
5. New geometries: Researchers create new shapes of artificial microcompartments
6. Oh, my stars and hexagons! DNA code shapes gold nanoparticles
7. Not a 1-way street: Evolution shapes environment of Connecticut lakes
8. Early music lessons boost brain development
9. Human brain is divided on fear and panic
10. Propping open the door to the blood brain barrier
11. Leadership Chair to champion tech devices for brain trauma, disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Epigenetics shapes fate of brain vs. brawn castes in carpenter ants
(Date:9/30/2014)... Health (NIH) awarded Lawrence Livermore National Laboratory (LLNL) ... system that will enable researchers to better understand ... scale. , LLNL,s grant-funded project is part of ... (Brain Research through Advancing Innovative Neurotechnologies) Initiative , ... of the human mind and uncover ways to ...
(Date:9/30/2014)... reports positive results of a phase 1 clinical ... lung cancer marked by rearrangement of the gene ROS1. ... non-small cell lung cancer testing positive for ROS1 gene ... complete responses and 33 partial responses. Median progression-free survival ... resume its growth after being slowed by treatment ...
(Date:9/30/2014)... it comes to using marijuana, new research, involving mice ... Journal of Leukocyte Biology , suggests ... that you should. That,s because a team of Italian ... do serious long-term damage to the immune system. This ... diseases, such as multiple sclerosis, inflammatory bowel disease and ...
Breaking Biology News(10 mins):NIH taps lab to develop sophisticated electrode array system to monitor brain act 2NIH taps lab to develop sophisticated electrode array system to monitor brain act 3NEJM: Crizotinib effective in Phase 1 trial against ROS1 lung cancer 2Adolescent exposure to thc may cause immune systems to go up in smoke 2
... to make someone say 'yes', coffee can help. ... the extent to which we can be persuaded, finds ... Psychology. , The Australian researchers from the University of ... likely to attend to, and agree with, persuasive arguments. ...
... Scientists have determined that decay-accelerating factor (DAF), a protein ... a receptor for the bacteria Helicobacter pylori. Blocking this ... risk of peptic ulcer disease or gastric cancer. The ... the May 12 issue of the Journal of Biological ...
... that degrades the body's collagen infrastructure has been shown to ... is stored in white adipose tissue, the primary energy depot ... by a University of Michigan team acts as a metabolic ... in place, which allows fat cells to expand beneath the ...
Cached Biology News:Stomach receptor for H. pylori discovered 2Expanding waistlines triggered by your genes 2
(Date:10/1/2014)... (PRWEB) September 30, 2014 New applications ... arrangements that have evolved in nature over millennia are ... bioinspired materials for applications in biophotonics in the ... . The journal is published by SPIE, the international ... Library. Several of the peer-reviewed articles are accessible via ...
(Date:10/1/2014)... TeselaGen Biotechnology has received a ... their bioCAD/CAM software suite, which uses synthetic biology ... Business Innovation Research Phase II grant will be used ... from the Lawrence Berkeley National Laboratory. j5 was developed ... laboratory that develops alternative fuel technologies for the Department ...
(Date:10/1/2014)... -- Industry leaders from retail pharmacies ... the theme, ,Commercial Opportunities in the Era of Reform, ... Elsevier , a world-leading provider of scientific, technical ... gathering of some of the industry,s most prominent healthcare ... and in the future. The Elsevier Healthcare ...
(Date:9/30/2014)... in German . ... (TUM) have demonstrated a new kind of building block ... computer chips could be based on three-dimensional arrangements of ... technology of the semiconductor industry CMOS fabrication of ... and collaborators at the University of Notre Dame are ...
Breaking Biology Technology:Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 2Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 3TeselaGen Receives $750k NSF SBIR Phase II Award 2TeselaGen Receives $750k NSF SBIR Phase II Award 3Elsevier Healthcare and Pharmaceutical Economics Conference 2014 To Convene Industry Leaders to Discuss Top Healthcare Business Issues 2Elsevier Healthcare and Pharmaceutical Economics Conference 2014 To Convene Industry Leaders to Discuss Top Healthcare Business Issues 3A new dimension for integrated circuits: 3-D nanomagnetic logic 2A new dimension for integrated circuits: 3-D nanomagnetic logic 3
... 1, 2011 MediVet-America today announced the opening ... provide technical support for in-clinic animal stem cell ... Cryogenic Banking Services, Autologous Conditional Serum Processing, and ... MediVet-America, the leading developer of stem ...
... about biology, the closer we get to being able to ... disease itself becomes. A new research finding showing ... and the common but serious medical condition known as fatty ... have learned that a mind-boggling multitude of different kinds of ...
... popular confidence trick known as "shell game," researchers at ... and shuffle "quantum-mechanical peas" microwave single photons ... In a paper published in the Jan. 30 ... the first demonstration of the coherent control of a ...
Cached Biology Technology:MediVet-America, Leading Animal Stem Cell Developer, Launches MediVet Lab Services 2Specific populations of gut bacteria linked to fatty liver 2Specific populations of gut bacteria linked to fatty liver 3Specific populations of gut bacteria linked to fatty liver 4UCSB physicists challenge classical world with quantum-mechanical implementation of 'shell game' 2
... Dodeca cell with multi-casting chamber is used for ... mini format handcast (8.3 x 7.3 cm) or ... requires 3.4-4.4 L of buffer and includes an ... to an external refrigerated circulator (not included), lid ...
...
... This product has been developed to ... peroxidase labeled proteins. Stability is increased ... to 2-8 centigrade. This product is ... no mercury or azide. This formulation ...
...
Biology Products: