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Engineering excitable cells for studies of bioelectricity and cell therapy
Date:7/19/2011

e stimulus to the modified cells in the center of the pathway, the electrical impulse travelled outwardly in both directions toward the heart cells and electrically activated them."

The Duke scientists also said that their engineered excitable cells can be continuously and easily grown in the lab, are genetically and functionally identical to each other, and also have the capacity for further modifications to change their electrical or structural behavior.

"These cells can be used in the laboratory as a platform for investigating the roles that specific ion channels have in tissue-level bioelectricity as well as testing the effectiveness of new drugs or therapies on bioelectrical activity," Kirkton said. "They could potentially also be helpful in the design of new biosensors to detect disease or environmental toxins.


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Contact: Richard Merritt
richard.merritt@duke.edu
919-660-8414
Duke University
Source:Eurekalert

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