Navigation Links
Effect of chronic exposure to chemicals used as weapons, pesticides under study

AUGUSTA, Ga. Soldiers in war zones and farmers tending their fields can have in common chronic exposure to chemicals that impact their nerves.

In large doses these agents, called organophosphates, are proven, rapid killers of people and pests that can also produce chronic disabilities such as problems with learning and memory, headaches and pain, said Dr. Alvin V. Terry Jr., pharmacologist at the Medical College of Georgia at Georgia Health Sciences University.

A Department of Defense grant is helping him document the less understood and probably more common - consquences of low-dose exposure for long periods.

"The use of these chemicals is like making the Faustian bargain," said Terry. "They are great for enhancing farming productivity and getting rid of vector-born illnesses like malaria and yellow fever, but they are almost ubiquitious in our environment." Conceding the last thing he wants is to encourage elimination of useful agents, he hopes instead that a prospective look at their cumulative toll will help identify ways to stop the ill effects.

"Once we have identified there is a problem and we know the mechanism, we have a much better chance of treating people," he said. Terry will be looking at varying doses of chlorpyrifos, an insecticide used by farmers and the military during the Gulf War, as well as the nerve agent, diisopropylfluorophosphate.

He is the first to look at the agents' impact on the axons, which enable brain cells to communicate.

"We are talking about the highway," he said of the pathway that has information, molecules, growth factors and other things made by the cells moving constantly in both directions. Terry is finding this fundamental brain function may be a particular target of chronic exposure to organophosphates. He's already shown animals with chronic exposure have impared communication in the body.

Now he's looking in the brain at axons a

Contact: Toni Baker
Georgia Health Sciences University

Page: 1 2 3

Related biology news :

1. Long-term study shows effect of climate change on animal diversity
2. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
3. Prolonged effects of a warming anomaly on grasslands
4. Cholesterol-lowering drugs and the effect on muscle repair and regeneration
5. Commercial aquatic plants offer cost-effective method for treating wastewater
6. Effects of anthropogenic sound on marine mammals -- a research strategy
7. UC Riverside biochemists devise method for bypassing aluminum toxicity effects in plants
8. How to build crops that can beat aluminums toxic effects
9. RNA molecules, delivery system improve vaccine responses, effectiveness
10. Ripple effect: Water snails offer new propulsion possibilities
11. Cost-effective farm waste-to-energy technology focus of research
Post Your Comments:
Related Image:
Effect of chronic exposure to chemicals used as weapons, pesticides under study
(Date:9/28/2015)... Calif. , Sept. 28, 2015 Synaptics ... human interface solutions, today announced that Lenovo has selected ... fingerprint sensor, FS4202, for its latest smartphone, the Vibe ... password-free access to unlock the device and provide swift ... The feature-rich Natural ID FS4202 sensor solution ...
(Date:9/10/2015)... , Sept. 10, 2015 Report Details ... Study Reveals Selling Opportunities and Revenue Prospects to ... future of biologics, especially new drug classes? Get ... stay ahead with exclusive market data and industry ... trends, developments, results, opportunities and sales predictions. ...
(Date:9/8/2015)... AUSTIN, Texas , Sept. 8, 2015   ... results of the new survey, Smart Marketing for ... survey of 580 engineering professionals reveals insightful findings about ... as the types of content engineers most value and ... Marketers targeting technical audiences grapple with ...
Breaking Biology News(10 mins):
... representing solar industry stakeholders has developed standard contracts that ... to access low-cost financing for residential and commercial solar ... (SAPC) working group, assembled by the Energy Department,s National ... developers, law firms, financiers and analysts with expertise in ...
... Cold Spring Harbor Laboratory (CSHL) today announced the launch of ... -- a new, free service, called bioRxiv (pronounced "bio-Archive"). ... share the results of their work before peer review and ... its contents costs nothing. Each paper is given a ...
... DETROIT Collaborating with researchers from the Northwestern University ... at Wayne State University,s School of Medicine led by ... in the inflammatory stress mechanism and specific inhibitor for ... by Zhang, associate professor of immunology and microbiology and ...
Cached Biology News:
(Date:10/8/2015)... 2015 .   ... Goldman Small Cap Research, a stock market ... microcap sectors, announced today that it has published ... Inc. (OTCQB - PMCB), a publicly traded, clinical ... treatments for cancer and diabetes. To view the ...
(Date:10/8/2015)...  The ALS Association, in partnership with Prize4Life, is ... revolutionize communication technology solutions for people living with ALS. ... (amyotrophic lateral sclerosis) is a progressive neurodegenerative disease that ... spinal cord. Eventually, people with ALS lose the ability ... to total paralysis and death within two to five ...
(Date:10/8/2015)... ... , ... Talon Innovations, a provider of Precision Machined Products and ... is one of three finalists for the Minnesota Business magazine’s Manufacturing Award in the ... Innovations was recognized as a nominee for this competitive award. , The “Best ...
(Date:10/7/2015)... , Oct. 7, 2015 Boston ... the start of the Boston Scientific Connected Patient ... advancements in the use of remote patient monitoring to ... designers and entrepreneurs can submit their ideas and collaborate ... ( ). Cambridge, MA ...
Breaking Biology Technology:
... PARK, N.C., Nov. 16, 2010 Scientists from ... data demonstrating that the company,s lipid-conjugated drugs, CMX001 ... Organic Anion Transporters (hOATs) and thus have significantly ...  These data, presented at the International Pharmaceutical Federation ...
... has announced the winners of its 2010 Photo Prize ... and Mario Pereda from Spain were awarded first, second ... respectively. The winning photos were selected from 3800 entries, ... interpretation of Syngenta,s purpose: Bringing plant potential to life. ...
... announces that a new market research report ... Global Specialty Enzymes Industry ... worldwide markets for Specialty Enzymes in US$ Million ... Enzymes, Polymerases, Nucleases, and Other Specialty Enzymes. The ...
Cached Biology Technology:
... human XAB2 (amino terminus) XAB2 (XPA-binding ... interaction with XPA. Immunoprecipitation experiments have also ... with the transcription-coupled repair-specific proteins CSA and ... II. Microinjection experiments with XAB2 antibodies resulted ...
... maintenance, calibration, and validation (MCV) ... 96-well plate used for hands-free ... procedures using the Bio-Plex suspension ... is for use with Bio-Plex ...
Biology Products: