Navigation Links
Early warning system for seizures could cut false alarms
Date:4/3/2012

Epilepsy affects 50 million people worldwide, but in a third of these cases, medication cannot keep seizures from occurring. One solution is to shoot a short pulse of electricity to the brain to stamp out the seizure just as it begins to erupt. But brain implants designed to do this have run into a stubborn problem: too many false alarms, triggering unneeded treatment. To solve this, Johns Hopkins biomedical engineers have devised new seizure detection software that, in early testing, significantly cuts the number of unneeded pulses of current that an epilepsy patient would receive.

Sridevi V. Sarma, an assistant professor of biomedical engineering, is leading this effort to improve anti-seizure technology that sends small amounts of current into the brain to control seizures.

"These devices use algorithms -- a series of mathematical steps --to figure out when to administer the treatment," Sarma said. "They're very good at detecting when a seizure is about to happen, but they also produce lots of false positives, sometimes hundreds in one day. If you introduce electric current to the brain too often, we don't know what the health impacts might be. Also, too many false alarms can shorten the life of the battery that powers the device, which must be replaced surgically."

Her new software was tested on real-time brain activity recordings collected from four patients with drug-resistant epilepsy who experienced seizures while being monitored. In a study published recently in the journal Epilepsy & Behavior, Sarma's team reported that its system yielded superior results, including flawless detection of actual seizures and up to 80 percent fewer alarms when a seizure was not occurring. Although the testing was not conducted on patients in a clinical setting, the results were promising.

"We're making great progress in developing software that is sensitive enough to detect imminent seizures without setting off a large number of false
'/>"/>

Contact: Phil Sneiderman
prs@jhu.edu
443-287-9960
Johns Hopkins University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Stevens strengthens Dominican Republics Early Warning System for Inundations
2. Reproducing early and often is the key to rapid evolution in plants
3. Early-stage gene transcription creates access to DNA
4. Global Viral Forecasting Initiative receives $11M to implement pandemic early warning system
5. Baby talk: The roots of the early vocabulary in infants learning from speech
6. Gaining too much weight during pregnancy nearly doubles risk of having a heavy baby
7. Hypertension develops early, silently, in African-American men
8. Joslin research finds nearly three-quarters of youths with diabetes insufficient in vitamin D
9. Study: Did early climate impact divert a new glacial age?
10. Water in the early universe
11. Haag honored with Presidential Early Career Scientists Award
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Early warning system for seizures could cut false alarms
(Date:4/23/2014)... in French and German . ... humans and other mammals, the difference between sexes depends on one ... only in males, where the two sexual chromosomes are X and ... ultimately responsible for all the morphological and physiological differences between males ... A very long time ago, the X and Y were identical, ...
(Date:4/23/2014)... Scarborough research shows that male black widow spiders prefer ... rare example of mate preference by male spiders. ... MacLeod and Maydianne Andrade, a professor in UTSC,s Department ... and the wild that males overwhelmingly chose to mate ... widows can tell whether a potential mate is well-fed ...
(Date:4/23/2014)... (4/23/14) -- Researchers have found evidence of an ... that increase aggressive behavior in children, especially in ... all children exposed to prenatal smoking will have ... not," said Brian Boutwell, Assistant Professor at Sam ... senior author on the study. "One possible ...
Breaking Biology News(10 mins):Male or female? 2Male or female? 3Picky male black widow spiders prefer well-fed virgins 2Genetics risk, prenatal smoking may predict behavioral problems 2
... Clonorchis sinensis affects more than 35 million people ... by this parasite causes clonorchiasis. Repeated or chronic infection can ... bile ducts, including the frequently fatal bile duct cancer - ... C. sinensis , published in BioMed Central,s open access journal ...
... researchers found a way of identifying ideal drug combinations ... occurring. The findings, published in Nature Chemical ... development of new drug combinations to combat severe diseases ... stroke and Alzheimer,s are worsened by inflammation, which is ...
... genetically engineered clotting factor that controlled hemophilia in an ... hemophilia and a broad range of other bleeding problems. ... Xa (FXa), a protein active in blood clotting, and ... bleeding in mouse models of hemophilia. "Our designed variant ...
Cached Biology News:Liver parasite lacks key genes for fatty acid synthesis: Genome sequencing of Clonorchis sinensis 2Manchester's 'first step' to perfect drug combinations 2Bioengineered protein shows preliminary promise as new therapy for hemophilia 2
(Date:1/15/2014)... "The interface is the device," Nobel laureate Herbert ... to be found at the junctures where layers ... of nanotechnology, the interfaces between layers of metal ... such high-tech favorites as spintronics, high-temperature superconductors, ferroelectrics ...
(Date:1/15/2014)... 15, 2014 Cynvenio, a cancer diagnostics ... the genomic analysis of tumor cells in the bloodstream, ... web-based cancer decision support application powered by CollabRx, Inc. ... ClearID™ genomic test, Therapy Finder will provide breast cancer ...
(Date:1/15/2014)... More than 5 million Americans are currently ... seniors will die with Alzheimer’s or another dementia, according ... shocked many Americans into looking for ways to improve ... age-related cognitive disorders. Jonathan Weisman, president of Biohack Pure, ...
(Date:1/15/2014)... Freeslate, Inc ., the leading ... Lupin Limited, one of India’s top five pharmaceutical companies, ... System for high throughput solid form screening. ... a wide range of quality, affordable generic and branded ...
Breaking Biology Technology:A deeper look at interfaces 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3
... OMAHA, Neb., April 1, 2011 Transgenomic, ... scientists have completed studies employing the company,s high-sensitivity ... COLD-PCR and BLOCker™-Sequencing.  Results from these studies will ... Research (AACR) meeting in Orlando, Florida, April 2-6, ...
... National Institute of Standards and Technology (NIST) have developed a ... probes used to study nanoscale structures in situ and as ... improve the accuracy of the most precise and delicate nanoscale ... trying to measure the contours of a surface with a ...
... /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc. (Nasdaq: CHBT ) ... distributor of probiotics products in China, today announced that ... its newly signed U.S. customer. The U.S. ... and formally entered into its agreement with China-Biotics on ...
Cached Biology Technology:Transgenomic, Inc. Presentations to Describe High-Sensitivity Detection of Cancer Biomarkers at the 2011 American Association for Cancer Research Meeting 2Transgenomic, Inc. Presentations to Describe High-Sensitivity Detection of Cancer Biomarkers at the 2011 American Association for Cancer Research Meeting 3Transgenomic, Inc. Presentations to Describe High-Sensitivity Detection of Cancer Biomarkers at the 2011 American Association for Cancer Research Meeting 4Getting the point: Real-time monitoring of atomic-microscope probes adjusts for wear 2China-Biotics Receives First U.S. Sales Order 2China-Biotics Receives First U.S. Sales Order 3
... a software package that provides crystallographers ... custom buffer creation, set-up of experimental ... trials. The software helps crystallographers through ... protein crystallography: Design ...
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
Mouse monoclonal [H4B4] to LAMP2 - Lysosome Marker (Phycoerythrin) ( Abpromise for all tested applications). entrezGeneID: 3920 SwissProtID: P13473...
... imaging software for the microscopy market ... cameras, components and peripherals with powerful ... Its intuitive interface simplifies workflow and ... providing powerful features such as image ...
Biology Products: