Navigation Links
Earlier bites by uninfected mosquitoes boost West Nile deaths in lab mice
Date:11/15/2007

GALVESTON, Texas Theres one more reason to try to avoid being bitten by mosquitoes, scientists have discovered: bites from mosquitoes that arent infected by the West Nile virus may make the disease worse in people who acquire it later from West Nile-infected mosquitoes.

Researchers from the University of Texas Medical Branch at Galveston (UTMB) announced their discovery in a paper published online by the journal PLoS ONE. In the paper, they describe experiments showing that lab mice on which mosquitoes have previously fed are far more likely to die from West Nile infection than are mice unexposed to such mosquito bites.

The effect is induced by mosquito saliva, according to UTMB professor Stephen Higgs, one of the papers senior authors.

This virus is transmitted from mosquitoes in saliva, and wed already demonstrated that mosquito saliva has an effect on the vertebrate immune system that makes West Nile infection worse, Higgs said. What this new work shows is that the saliva delivered by even earlier feedings can also alter the course of the infection. This is important, because in natural situations in many parts of the world Southeast Texas, for example animals and some people are being exposed to mosquito feeding almost continuously.

In their experiments, researchers exposed sedated mice to feeding by between 15 and 20 Aedes aegypti mosquitoes for an hour once a week. Scientists then allowed a single West Nile virus-infected mosquito to feed once on each of these mice and also on each of a control group of mice that were previously unbitten by mosquitoes.

The results were striking: 68 percent of mice exposed to two weekly mosquito feedings died of West Nile virus, and those exposed to four weekly mosquito feedings suffered a 91 percent mortality rate. By contrast, the virus killed only 27 percent of the mice previously unexposed to saliva from mosquitoes that were free of West Nile infection. Analyses of res
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2

Related biology news :

1. New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed
2. Researchers detect hint of oxygen 50 to 100 million years earlier than first believed
3. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
4. Rutgers high school outreach gets $3 million boost from NSF
5. Breast cancer research and inkjet tissue printing get NSF boost
6. Breastfeeding boost IQ in infants with helpful genetic variant
7. Small-scale fishing in Mexico rivals industrial fisheries in accidental turtle deaths
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/12/2014)... and POINT ROBERTS, Washington , ... Investorideas.com ( http://www.investorideas.com ) a global news source covering leading ... and experts on the September 9 th launch of ... of Goode Intelligence, Janice Kephart , founder of the ... Pereira of NXT-ID, Inc, (NASDAQ: NXTD ) ...
(Date:9/11/2014)... Ill. Chicago residents today might have had a ... of Illinois had been approved. It was a straight ... just south of the Rock and Mississippi River confluence. ... had the proposed northern border not been changed, the ... and footprint with the northern 51 miles of the ...
(Date:9/11/2014)... Two Northeastern University researchers and their international colleagues ... the role of neutral evolution in the biogeographic ... published Thursday in the journal Science . ... in a neutral agent-based model"was co-authored by Ferdi ... professor of civil and environmental engineering; his doctoral ...
Breaking Biology News(10 mins):Biometric Experts Comment on Launch of Apple Pay Smart Wallet Payment Service 2Biometric Experts Comment on Launch of Apple Pay Smart Wallet Payment Service 3Biometric Experts Comment on Launch of Apple Pay Smart Wallet Payment Service 4Biometric Experts Comment on Launch of Apple Pay Smart Wallet Payment Service 5Original northern border of Illinois was south of Chicago and Lake Michigan 2Original northern border of Illinois was south of Chicago and Lake Michigan 3Microbes evolve faster than ocean can disperse them 2
... I. Gordon, MD, at Washington University School of Medicine in ... find new ways to diagnose, treat and prevent a critical ... is funded by an $8.3 million grant from the Bill ... link between obesity and the trillions of friendly microbes that ...
... nowadays. It is quite unexceptional for a sports jacket, ... the case of working clothes, the functionality is mostly ... and so on, with wearer comfort (mostly) not being ... their name suggests, hold off bullets but they are ...
... the Salk Institute for Biological Studies and Iowa State ... a role in the production of seed oils, substances ... biofuels. Scoring a rare scientific hat trick, the ... plants ( Arabidopsis thaliana ) that regulate the metabolism ...
Cached Biology News:Washington University receives $8 million to lead international childhood malnutrition effort 2Washington University receives $8 million to lead international childhood malnutrition effort 3Washington University receives $8 million to lead international childhood malnutrition effort 4Real smart: Protective clothing with built-in A/C 2Discovery of plant proteins may boost agricultural yields and biofuel production 2Discovery of plant proteins may boost agricultural yields and biofuel production 3
(Date:9/12/2014)... using an electric field (magnetoelectric memory [MEM] effect), ... technology for information processing and storage. Multiferroic materials ... to the coexistence of electric and magnetic orders. ... electric and magnetic polarizations is rare in known ... MEM effect. This article briefly reviews a new ...
(Date:9/12/2014)... Worcester, Mass. (PRWEB) September 12, 2014 ... the detection and decontamination of chemical and biological ... workshop organized by Worcester Polytechnic Institute (WPI) and ... sponsored by the Science for Peace and Security ... , Part of NATO’s Advanced Research Workshop series, ...
(Date:9/12/2014)... CA (PRWEB) September 12, 2014 Today, ... campaign on Indiegogo. , The film, directed by ... Buzz Aldrin, Shimon Peres, Ashton Kutcher, Will.i.Am, Michio Kaku, ... world and there’s only one university in the world ... help change the lives of a billion people: Singularity ...
(Date:9/12/2014)... Albuquerque, NM (PRWEB) September 12, 2014 ... signed an exclusive option agreement with STC.UNM (STC) for ... New Mexico (UNM) in Albuquerque, New Mexico, and Queen ... group of technologies, called the Recombinant Fluorescent Antibody Technology ... UNM’s Department of Internal Medicine and Dr. Angray Kang ...
Breaking Biology Technology:Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 3Documentary Film that Follows Singularity University Students as They Change the World Launches its IndieGoGo Fundraising Campaign 2Sandia Biotech and STC.UNM Announce Option Agreement to License Novel Recombinant Antibody Technology 2Sandia Biotech and STC.UNM Announce Option Agreement to License Novel Recombinant Antibody Technology 3Sandia Biotech and STC.UNM Announce Option Agreement to License Novel Recombinant Antibody Technology 4
... one of the best possible technologies for providing ... to power our civilization. However, for this dream to ... inexpensive elements using low-cost, less energy-intensive processing chemistry, and ... electricity. A team of researchers with the U.S. Department ...
... SynCardia Systems, Inc. ( www.syncardia.com ), manufacturer of the SynCardia ... company pages on Facebook , Twitter and ... about the world,s only FDA, Health Canada and CE (Europe) ... implants of the Total Artificial Heart, accounting for more than ...
... 31, 2011 BioMed Realty Trust, Inc. (the "Company") ... of the 4.50% Exchangeable Senior Notes due 2026 (CUSIP ... Realty, L.P. (the "Operating Partnership"), which are fully and ... surrender their Notes for purchase by the Operating Partnership ...
Cached Biology Technology:Down to the wire 2Down to the wire 3Down to the wire 4SynCardia Goes Social on Facebook, Twitter and LinkedIn 2SynCardia Goes Social on Facebook, Twitter and LinkedIn 3SynCardia Goes Social on Facebook, Twitter and LinkedIn 4BioMed Realty Announces Repurchase at Option of Holders and Redemption of 4.50% Exchangeable Senior Notes Due 2026 2BioMed Realty Announces Repurchase at Option of Holders and Redemption of 4.50% Exchangeable Senior Notes Due 2026 3BioMed Realty Announces Repurchase at Option of Holders and Redemption of 4.50% Exchangeable Senior Notes Due 2026 4BioMed Realty Announces Repurchase at Option of Holders and Redemption of 4.50% Exchangeable Senior Notes Due 2026 5