Navigation Links
Earlier bites by uninfected mosquitoes boost West Nile deaths in lab mice
Date:11/15/2007

GALVESTON, Texas Theres one more reason to try to avoid being bitten by mosquitoes, scientists have discovered: bites from mosquitoes that arent infected by the West Nile virus may make the disease worse in people who acquire it later from West Nile-infected mosquitoes.

Researchers from the University of Texas Medical Branch at Galveston (UTMB) announced their discovery in a paper published online by the journal PLoS ONE. In the paper, they describe experiments showing that lab mice on which mosquitoes have previously fed are far more likely to die from West Nile infection than are mice unexposed to such mosquito bites.

The effect is induced by mosquito saliva, according to UTMB professor Stephen Higgs, one of the papers senior authors.

This virus is transmitted from mosquitoes in saliva, and wed already demonstrated that mosquito saliva has an effect on the vertebrate immune system that makes West Nile infection worse, Higgs said. What this new work shows is that the saliva delivered by even earlier feedings can also alter the course of the infection. This is important, because in natural situations in many parts of the world Southeast Texas, for example animals and some people are being exposed to mosquito feeding almost continuously.

In their experiments, researchers exposed sedated mice to feeding by between 15 and 20 Aedes aegypti mosquitoes for an hour once a week. Scientists then allowed a single West Nile virus-infected mosquito to feed once on each of these mice and also on each of a control group of mice that were previously unbitten by mosquitoes.

The results were striking: 68 percent of mice exposed to two weekly mosquito feedings died of West Nile virus, and those exposed to four weekly mosquito feedings suffered a 91 percent mortality rate. By contrast, the virus killed only 27 percent of the mice previously unexposed to saliva from mosquitoes that were free of West Nile infection. Analyses of res
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2

Related biology news :

1. New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed
2. Researchers detect hint of oxygen 50 to 100 million years earlier than first believed
3. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
4. Rutgers high school outreach gets $3 million boost from NSF
5. Breast cancer research and inkjet tissue printing get NSF boost
6. Breastfeeding boost IQ in infants with helpful genetic variant
7. Small-scale fishing in Mexico rivals industrial fisheries in accidental turtle deaths
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... Jan. 28, 2015 Research and Markets ... of the "Global Biometrics Market (2014-2020): Market ... Countries " report to their offering. , ... Asia-Pacific is anticipated to overtake ... to increasing government spending towards IT security, government ...
(Date:1/22/2015)... , Jan. 9, 2015 Valid S.A. ("Company") (BM&FBOVESPA: VLID3 ... in general the State of Washington,s ... a new enrollment and central issuance system for driver,s licenses ... The project planning and development will start in January ...
(Date:1/22/2015)... Wis. , Jan. 15, 2015  BellBrook Labs, ... drug discovery, announced the launch of a TR-FRET ... the company,s Transcreener UDP Assay, a high throughput ... The new assay will allow for sensitive detection ...
Breaking Biology News(10 mins):Global Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, End Use, Regions and Countries 2Global Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, End Use, Regions and Countries 3Valid USA Signs Contract For Washington Driver's License Issuance 2BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2
... supermarket headlines tell us so., Inquiring Texas research minds ... tiny, sometimes obscure pest that can damage plants during ... cotton for about four weeks," said Dr. Megha Parajulee, ... feed on new plant growth, primarily the first small ...
... ago, "ultraconserved elements" were discovered in the genomes of mice, ... in length or longer -- some are over 700 base ... three species. They have been perfectly conserved since the last ... 85 million years ago. These and other highly ...
... cells could take a mix of enzyme ingredients, blend ... elaborate chemical structure such as penicillin. Researchers at UC ... of Pharmacy and Pharmaceutical Sciences and the University of ... to mimic this process outside of a cell. ...
Cached Biology News:Inquiring minds want to know about cotton fleahoppers 2Inquiring minds want to know about cotton fleahoppers 3Ultraconserved elements in the genome: Are they indispensable? 2Ultraconserved elements in the genome: Are they indispensable? 3Ultraconserved elements in the genome: Are they indispensable? 4Researchers develop simple method to create natural drug products 2
(Date:3/4/2015)... 04, 2015 Follow us on ... of the fastest growing technologies in the life sciences ... visualization is driving growth in nucleic acid detection technologies ... of gene expressions will continue to benefit the qPCR ... fields ranging from pharma, biotech, food & beverage to ...
(Date:3/4/2015)... , March 4, 2015 ... Paris en décembre 2011, ... SARAH   », qui compare   l ... le   sorafénib dans le carcinome hépatocellulaire avancé, ... cancer du foie avancé   ; les résultats ...
(Date:3/3/2015)... DIEGO and TORONTO, March 3, 2015 /PRNewswire/ - Aptose ... developing new therapeutics and molecular diagnostics that target the ... the quarter and seventh-month period ended December 31, 2014. ... its fiscal year end from May 31 to December ... we are reporting today are for the quarter and ...
(Date:3/3/2015)... , March 3, 2015 NASA astronaut Scott ... this month to spend a year living and working on ... interviews from 5:30 to 7 a.m. EDT Monday, March 9. ... as he completes the final weeks of his training. ... video on NASA Television highlighting his mission training and previous ...
Breaking Biology Technology:Focus on Quantifying Nucleic Acid Molecules Spurs Growth in the qPCR & dPCR Instrumentation Market, According to a New Report by Global Industry Analysts, Inc. 2Focus on Quantifying Nucleic Acid Molecules Spurs Growth in the qPCR & dPCR Instrumentation Market, According to a New Report by Global Industry Analysts, Inc. 3Focus on Quantifying Nucleic Acid Molecules Spurs Growth in the qPCR & dPCR Instrumentation Market, According to a New Report by Global Industry Analysts, Inc. 4Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 2Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 3Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 4Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 5Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 6Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 2Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 3Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 4Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 5Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 6Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 7Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 8Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 9Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 10Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 11Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 12NASA Astronaut Scott Kelly Available for Interviews before One-Year Space Station Mission 2
... YORK, October 25 XTL Biopharmaceuticals,Ltd. (NASDAQ: ... has,entered into definitive agreements with institutional investors relating ... million in gross proceeds of,ordinary shares, represented by ... transaction are Perceptive Life Sciences Fund, Quogue,Capital LLC, ...
... Innovative Fall Detection ... and Prevention System, FALLS CHURCH, ... in the elderly. The National Institute on Aging (NIA),part of the ... Business Innovation Research grant entitled,"Non-Intrusive Locomotion and Gait Stability Analysis Monitoring ...
... October 25 Glycominds Ltd., a,bio-diagnostics company specializing ... autoimmune diseases and cancer, announced today,entering into a ... an,NCI designated cancer center to develop a new ... very pleased to work with FCCC on this ...
Cached Biology Technology:XTL Biopharmaceuticals Ltd. Announces $9.6 Million Private Placement to Institutional Investors 2XTL Biopharmaceuticals Ltd. Announces $9.6 Million Private Placement to Institutional Investors 3Leading Edge Research Underway in Fall Prevention for Seniors 2Leading Edge Research Underway in Fall Prevention for Seniors 3Glycominds and Fox Chase Cancer Center Announce a Collaboration to Discover New Cancer Detection Diagnostic Tests 2
... Gelzyme is an agarose-digesting enzyme ... cleaves simple carbohydrate bonds in agarose ... longer gel. The remaining carbohydrate molecules ... manipulation. DNA isolated with Gelzyme enzyme ...
...
Coverslips for Microarrays, 1. *Category: MICROARRAY ACCESSORIES....
... 0 (or Cap 0-like) RNA into Cap ... been shown to increase in vivo translation ... is seen in Cap 0 structures created ... well as those Cap 0 structures created ...
Biology Products: