Navigation Links
Dividing cells 'feel' their way out of warp
Date:9/10/2009

Once the cells were warped, the scientists monitored the movements of fluorescent-tagged myosin II and cortexillin I. Myosin, which normally accumulates in the middles of cells during division to help power that process, collected instead at the sites of disturbances made by the micropipette. Also amassing with myosin was cortexillin I, a so-called actin-crosslinking protein that, like glue, holds the toothpick-like filaments of a cell's housing together.

In the experiments, as soon as the two proteins accumulated to a certain level, the cells contracted, escaping the pipettes and assuming their original shapes. After the cells righted themselves, the proteins realigned along the cells' midlines and pinched to divide symmetrically into two daughter cells.

The researchers repeated the experiment using cells engineered to lack myosin II and then again with cells lacking cortexillin I. They discovered that cortexillin I responded to deformations except when myosin II was removed, and myosin II responded to deformations except when cortexillin I was removed.

"It's clear that the two need each other to operate as a cellular mechanosensor," Robinson says.


'/>"/>

Contact: Maryalice Yakutchik
myakutc1@jhmi.edu
443-287-2251
Johns Hopkins Medical Institutions
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Carbon nanotubes could make efficient solar cells
2. Size of fat cells and waist size predict type 2 diabetes in women
3. Pandemic flu can infect cells deep in the lungs, says new research
4. Individual cells isolated from biological clock can keep daily time, but are unreliable
5. Researchers find first evidence of virus in malignant prostate cells
6. Liposuction leftovers easily converted to IPS cells, Stanford study shows
7. Making more efficient fuel cells
8. UT Southwestern researchers examine mechanisms that help cancer cells proliferate
9. Lower-cost solar cells to be printed like newspaper, painted on rooftops
10. Glow-in-the-dark red blood cells made from human stem cells
11. When cells run out of fuel
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Dividing cells 'feel' their way out of warp
(Date:7/13/2015)... OXFORD, Conn. , Jul. 13, 2015 /PRNewswire/ ... the "Company"), a biometric authentication company focused on ... it has filed provisional patent 62/188684 for ... NXT-ID achieves another new convenient and secure method ... expands new, innovative payment methods, introduced with its ...
(Date:7/9/2015)... 9, 2015  Synaptics Inc. (NASDAQ: ... interface solutions, today announced a new Match-in-Sensor™ ... hardware encapsulated fingerprint sensor and matching solution. ... literally off the grid, isolating fingerprint image ... the fingerprint sensor to provide ultimate protection ...
(Date:7/8/2015)... , July 8, 2015 The ... as this summer,s must have products such as wearables, smart ... as popularity for biometrics based devices continues to rapidly grow.  ... Inc. (NASDAQ: NXTD ), Google Inc. (NASDAQ: GOOG ... FIT ), GoPro, Inc. (NASDAQ: GPRO ) and ...
Breaking Biology News(10 mins):NXT-ID Patents Behavior-Directed Payments 2NXT-ID Patents Behavior-Directed Payments 3NXT-ID Patents Behavior-Directed Payments 4Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 2Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 2Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 4Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 5Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 6
... release is available in Spanish . Two ... Use stainless steel water troughs and add chlorine to the ... Service (ARS) microbiologist at the agency,s Animal Waste Management Research ... research with Carl Bolster, a hydrologist at Bowling Green, and ...
... any dog-lover or cat-lover that humans have a special ... journal article and forthcoming book, paleoanthropologist Pat Shipman of ... well beyond simple affection. Shipman proposes that the ... "the animal connection" -- played a crucial and beneficial ...
... fruit taste delicious and are important sources of energy. ... the cellulose in the cell wall. Even in ... the cell wall plays a crucial role in feed ... the digestibility of animal feed, and of utilising plant ...
Cached Biology News:Dairy farmers can fight growing disease threat with chlorine and stainless steel 2New hypothesis for human evolution and human nature 2New hypothesis for human evolution and human nature 3Cellulose: Hard to digest, but full of energy 2
(Date:7/29/2015)... , July 29, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: ... , the Company,s Chief Financial Officer has resigned.  The ... Chief Financial Officer who retired in December 2014, as ... for a permanent successor.     Andy Ashworth ... Laurin and ensure a smooth transition.  Andy was the ...
(Date:7/29/2015)... SAN FRANCISCO , July 29, 2015 /PRNewswire/ ... trialling mobile molecular testing for applications in food ... Ubiquitome,s hand-held, battery powered real-time PCR device, the ... the farm right through to the supermarket shelf ... world. This includes involvement in animal disease control ...
(Date:7/29/2015)... -- Research and Markets ( ... "Global Biosimilars Market, 2015 - 2025" ... Biosimilars Market, 2015 - 2025, report provides an ... With the blockbuster biologics losing patent protection and ... being viewed as viable substitutes to the highly ...
(Date:7/29/2015)... -- AmnioChor Inc., an early stage biotech startup based on ... that the Musculoskeletal Transplant Foundation of Edison ... seed round of development of the proprietary AmnioCept™ product ... AmnioChor,s technology allows cryopreservation of the amniotic membrane ... within those tissues. Amnion is a well-established source of ...
Breaking Biology Technology:BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3AsureQuality and Ubiquitome Partner on Applications for Mobile Molecular Food Safety Testing 2Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 2Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 3The Musculoskeletal Transplant Foundation Agrees to Invest in AmnioChor 2
... agriculture investors heard about using biomass and enzymes to ... annual meeting of Badger AgVest in Lake ... of the topics brought to the conference by the ... state. Though it doesn't make specific recommendations, AgVest tries ...
... 2004 and what impact will these have on the future? While ... of biotech and pharmaceuticals, the answer could be: , , 1. ... effects and the resultant scrutiny on the FDA for not being ... the recent Pfizer debacle with Celebrex in the last two days ...
... The University of Wisconsin Medical Schools dean of more than ... of 2005 to go back to research. , , Philip ... on cystic fibrosis, an inherited condition that leads to thick ... a dean, making advances such as a screening program for ...
Cached Biology Technology:Investors hear about new agricultural technology 2The greatest life-science developments of 2004 2The greatest life-science developments of 2004 3The greatest life-science developments of 2004 4The greatest life-science developments of 2004 5The greatest life-science developments of 2004 6The greatest life-science developments of 2004 7