Navigation Links
Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population
Date:12/2/2010

lly large, suggesting that the mosquitoes' fluid excretory function had been impeded. The researchers also found that in these mosquitoes, egg development, whose success is dependent on blood digestion, was severely inhibited.

"Our finding is exciting because it gets to the very core of what a vector of diseases is all about," said Alexander Raikhel, a distinguished professor of entomology, whose lab led the study. "We can now knock down a series of events starting with the digestion of blood and proceeding all the way to egg maturation simply by eliminating this small molecule, miR-275. In tropical areas of the world, where dengue and yellow fever are often leading causes of hospitalization and death among adults and children, a reduction in the number of Aedes aegypti mosquitoes would be tremendously beneficial."

Study results appear this week in the online edition of the Proceedings of the National Academy of Sciences.

Next in this line of work, Raikhel's lab plans to focus on determining which genes miR-275 targets, what roles these genes play in blood digestion and egg development, and what mechanism underlies the activation and deactivation of miR-275.

Bart Bryant, the first author of the research paper and a postdoctoral researcher in Raikhel's lab, explained that the research team knocked down or "depleted" the miR-275 with an "antagomir" a small synthetic RNA molecule that in this research study binds with miR-275, preventing it from doing its job of allowing blood digestion and egg development to proceed.

"We think our work has opened the door for exploring how microRNAs regulate critical physiological functions specific to vectors that transmit deadly disease pathogens," Bryant said.


'/>"/>

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Strange discovery: Bacteria built with arsenic
2. Mystery dissolves with calcium pump discovery
3. In new novel, secret discovery threatens company and damages love affair
4. New sleep cycle discovery explains why fatty diets during pregnancy make kids obese
5. Gene discovery suggests way to engineer fast-growing plants
6. TB-drugome provides new targets for anti-tuberculosis drug discovery
7. Discovery of an anti-inflammatory substance
8. A discovery could be important for the therapy of lymphoma and leukemia
9. AACR announces new journal, Cancer Discovery
10. Swan song of space shuttle Discovery to carry 2 payloads built by CU-Boulder
11. Discovery of taste receptors in the lungs could help people with asthma breathe easier
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population
(Date:11/4/2014)... 4, 2014   Neurotechnology , a provider ... the latest version of its fingerprint matching algorithm ... MINEX evaluation organized by NIST. The MINEX ... the INCITS 378 fingerprint standard template format. MINEX ... tenders in the United States ...
(Date:11/3/2014)... study published in this month,s Proceedings of ... of a recently discovered communication molecule of the body,s ... known to limit inflammation and the current study reports ... the ability of the immune system to recognize and ... IL-37,s effect on the immune system now allows us ...
(Date:11/3/2014)... weight and preterm birth are linked to increased risk ... in the American College of Rheumatology (ACR) journal, ... weight and pre-term babies were not at greater risk ... , According to the ACR, 27 million Americans over ... Symptoms of OA range from mild to severe and ...
Breaking Biology News(10 mins):Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3PNAS: From HIV to cancer, IL-37 regulates immune system 2Preterm, low birth-weight babies may need new hips in adulthood 2
... who have adapted a three-dimensional, general circulation model of ... ago when the sun was significantly fainter than present ... catastrophic glaciation than previously believed. The new 3-D ... from about 3.8 billion years to 2.5 billion years ...
... Managing commercial and recreational fisheries is a complex ... and regulatory agencies don,t always see eye-to-eye. Researchers ... now working with commercial fishermen to collect and share ... build trust and foster the mutual goal of sustainable ...
... neurodegenerative diseases such as Parkinson,s and Alzheimer,s, cancer and ... partially caused or accelerated by oxidative stress. Oxidative stress ... what are called reactive oxygen species (ROS). "However, up ... changes in a living organism and certainly not how ...
Cached Biology News:Early Earth may have been prone to deep freezes, says CU-Boulder study 2Early Earth may have been prone to deep freezes, says CU-Boulder study 3Public-private partnership helps monitor fish populations 2Public-private partnership helps monitor fish populations 3Public-private partnership helps monitor fish populations 4Public-private partnership helps monitor fish populations 5Oxidative stress: Less harmful than suspected? 2
(Date:11/26/2014)... Chester, OH (PRWEB) November 25, 2014 ... Holdings, has joined the Graphel Carbon Products team as ... in sales, marketing, and customer service for the graphite ... add Miles to our team,” stated Dave Trinkley, VP ... “His wide range of experience in the graphite ...
(Date:11/26/2014)... , 25 novembre 2014 Theravalues Corporation ... sur le marché européen au salon Hi Europe ... Amsterdam ). Curcumine la plus ... technologie amorphe (non-cristalline) à des ingrédients approuvés par ... un pigment jaune présent dans la racine de ...
(Date:11/24/2014)... BUENA, N.J. , Nov. 24, 2014  IGI ... Jersey based specialty generic pharmaceutical company, today ... application (ANDA) to the U.S. Food and Drug Administration ... submissions in 2014 to seven, with eighteen submissions now ... Grenfell-Gardner , President and CEO of the Company, commented, ...
(Date:11/24/2014)... November 24, 2014   ... ScienceDirect   Elsevier , a world-leading provider ... pleased to announce the launch of the latest title in ... Current Opinion in Food Science . ... specialists with a new platform to keep up-to-date with the ...
Breaking Biology Technology:Miles Holder Joins Graphel Corporation as Sales/Marketing Manager 2La curcumine présentant la plus haute biodisponibilité bientôt en vente en Europe 2La curcumine présentant la plus haute biodisponibilité bientôt en vente en Europe 3IGI Laboratories, Inc. Announces ANDA Submission 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 3
... Brings Both Clinical Trial Experience and Business ... Role, CAMBRIDGE, Mass., Jan. 16 Cytel, ... executive Irving Dark has,accepted the role of Vice ... to Cytel 15-years of management experience guiding drug,biologic ...
... BASEL, Switzerland, Jan. 16 Roche (OTCQX:,RHHBY; SWX: ROG.VX; ... today that it has extended its,offer to acquire all ... (Nasdaq: VMSI ) to 5:00 p.m., New York ... was previously scheduled to expire at 5:00,p.m., New York ...
... NEW YORK, Jan. 16 With the field ... research, the Society for Biological Engineering,(SBE) has organized ... conference, which runs from January 20th to 23rd ... will focus on,engineering designs for stem cell production, ...
Cached Biology Technology:Irving Dark Named Vice President of Cytel Clinical Research Services 2Roche Extends Tender Offer for Ventana 2Roche Extends Tender Offer for Ventana 3Roche Extends Tender Offer for Ventana 4Roche Extends Tender Offer for Ventana 5Society for Biological Engineering Holds First International Conference on Stem Cell Engineering 2
... Panels were designed for full-length gene cloning ... to identify the desired cDNA clone. The ... 96-well "Master Plate," where each well contains ... the positive well(s) by gel electrophoresis of ...
... Preparation Note: Prepared by a ... C.W., et al., Biotechnol. Bioeng., ... Definition: One unit will yield an ... 1.0 ml of water (1 cm ...
... Dithiothreitol DTT White solid.. ... disulfides to thiols, so reaction is "driven" to ... not contain waxy surfactant found in many other ... pentobarbitol. Purity: ≥97% by titration. ...
... Basically, most ``special`` dye stains are ... few other non-routine) stains are $9.00. ... a paraffin block, staining, coverslipping and ... (for senile plaques) ,Bodian`s Stain ,Copper ...
Biology Products: