Navigation Links
Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population
Date:12/2/2010

lly large, suggesting that the mosquitoes' fluid excretory function had been impeded. The researchers also found that in these mosquitoes, egg development, whose success is dependent on blood digestion, was severely inhibited.

"Our finding is exciting because it gets to the very core of what a vector of diseases is all about," said Alexander Raikhel, a distinguished professor of entomology, whose lab led the study. "We can now knock down a series of events starting with the digestion of blood and proceeding all the way to egg maturation simply by eliminating this small molecule, miR-275. In tropical areas of the world, where dengue and yellow fever are often leading causes of hospitalization and death among adults and children, a reduction in the number of Aedes aegypti mosquitoes would be tremendously beneficial."

Study results appear this week in the online edition of the Proceedings of the National Academy of Sciences.

Next in this line of work, Raikhel's lab plans to focus on determining which genes miR-275 targets, what roles these genes play in blood digestion and egg development, and what mechanism underlies the activation and deactivation of miR-275.

Bart Bryant, the first author of the research paper and a postdoctoral researcher in Raikhel's lab, explained that the research team knocked down or "depleted" the miR-275 with an "antagomir" a small synthetic RNA molecule that in this research study binds with miR-275, preventing it from doing its job of allowing blood digestion and egg development to proceed.

"We think our work has opened the door for exploring how microRNAs regulate critical physiological functions specific to vectors that transmit deadly disease pathogens," Bryant said.


'/>"/>

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Strange discovery: Bacteria built with arsenic
2. Mystery dissolves with calcium pump discovery
3. In new novel, secret discovery threatens company and damages love affair
4. New sleep cycle discovery explains why fatty diets during pregnancy make kids obese
5. Gene discovery suggests way to engineer fast-growing plants
6. TB-drugome provides new targets for anti-tuberculosis drug discovery
7. Discovery of an anti-inflammatory substance
8. A discovery could be important for the therapy of lymphoma and leukemia
9. AACR announces new journal, Cancer Discovery
10. Swan song of space shuttle Discovery to carry 2 payloads built by CU-Boulder
11. Discovery of taste receptors in the lungs could help people with asthma breathe easier
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population
(Date:10/15/2014)... to an unexpected extent. The outbreak does not follow ... shows a new disease dynamic in regions, where it ... German National Academy of Sciences Leopoldina, acatech – the ... of the German Academies of Sciences and Humanities have ... In the statement the academies call for the following ...
(Date:10/15/2014)... , Oct. 15, 2014   Neurotechnology , ... announced the availability of the VeriLook Surveillance ... 3.0 provides real-time biometric face identification using live ... surveillance cameras. The new version not only identifies ... people from objects while they are moving through ...
(Date:10/14/2014)... fly genome for the first time, revealing robust immune ... thrives in pathogen-rich dung piles and garbage heaps. , ... Genome Biology , will increase understanding of house fly ... to resist insecticides, which could lead to novel control ... transmit more than 100 human and animal diseases, including ...
Breaking Biology News(10 mins):Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3House fly genome reveals expanded immune system 2
... Sex may in fact be one of the secrets to ... fruit flies suggests a new University of Michigan study that ... flies that perceived sexual pheromones of their female counterparts without ... resistance to starvation and more stress. The sexually frustrated flies lived ...
... are paving the way for fishing fleets to reel in ... profits, according to University of British Columbia researchers. In ... ONE , researchers from UBC,s Fisheries Centre analyzed access agreements ... the South Pacific. They found that EU governments pay 75 ...
... NY (November 27, 2013) An international team of scientists, including ... key metabolic enzyme that common malaria parasites require for survival ... the possibility of a new approach to combating malaria, one ... in the online edition of the journal Nature . ...
Cached Biology News:Fruit flies with better sex lives live longer 2Study finds new vulnerability in malaria parasite 2
(Date:10/18/2014)... (PRWEB) October 18, 2014 The Asian Electronic ... market in Asian with analysis and forecast of revenue. The ... to grow to $2,328.0 million by 2018, at a CAGR ... TOC of the Asian Electronic Medical Record (EMR) market, to ... provides a glimpse of the segmentation of the market in ...
(Date:10/18/2014)... The report " Cloud Analytics Market [Cloud ... Machine; Video; Predictive Analytics: Global Advancements, Delivery Models, ... (2013 - 2018) ", defines and segments the ... with an in-depth analysis and forecasting of market ... this market, various restraints, and opportunities impacting it ...
(Date:10/17/2014)... 16—As in Alice,s journey through the looking-glass to Wonderland, ... surprising and unexpected ways, including a new class of ... reported today in The Optical Society,s (OSA) new high-impact ... for the first time, a new type of mirror ... reflects infrared light by using an unusual magnetic property ...
(Date:10/17/2014)... 2014 Bioquell, provider of germ-eliminating ... health facilities around the world to decontaminate locations ... Among the many places the hydrogen peroxide vapor ... Hospital Dallas and at the National Institutes of ... have been utilized to decontaminate patient rooms, equipment, ...
Breaking Biology Technology:The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 2The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 3The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 4The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 5Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 2Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 3Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 4Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 5Magnetic mirrors enable new technologies by reflecting light in uncanny ways 2Magnetic mirrors enable new technologies by reflecting light in uncanny ways 3Magnetic mirrors enable new technologies by reflecting light in uncanny ways 4Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 2Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 3Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 4Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 5Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 6
... , New Vitality hrGFP expression vectors , ... Expression Vectors Employ Stable, High-Level Fluorescence , Humanized Renilla GFP Reporter , ... , ... , Stratagene , , ...
... of FLAG -Tagged Fusion Proteins ,,,,, Detection of expressed ... of FLAG -Tagged,Fusion Proteins , Qiyi ... Weiping Yang ,Stratagene , Stratagenes TagDetect FLAG ... an easy-to-use assay kit for detecting FLAG epitope-tagged fusion,proteins. To ...
... assists in detecting SNPs,quickly and easily , ... University of Colorado Health Sciences Center, ... custom molecular beacons ff, ,to detect a single ... clear discrimination among the different genotypes carried in,family members. This ...
Cached Biology Technology:New Mammalian Expression Vectors Employ Stable, High-Level Fluorescence , Humanized Renilla GFP Reporter 2New Mammalian Expression Vectors Employ Stable, High-Level Fluorescence , Humanized Renilla GFP Reporter 3New Mammalian Expression Vectors Employ Stable, High-Level Fluorescence , Humanized Renilla GFP Reporter 4New Mammalian Expression Vectors Employ Stable, High-Level Fluorescence , Humanized Renilla GFP Reporter 5New Mammalian Expression Vectors Employ Stable, High-Level Fluorescence , Humanized Renilla GFP Reporter 6New Mammalian Expression Vectors Employ Stable, High-Level Fluorescence , Humanized Renilla GFP Reporter 7Simple, Sensitive, and Rapid Detection of FLAG -Tagged,Fusion Proteins 2Simple, Sensitive, and Rapid Detection of FLAG -Tagged,Fusion Proteins 3Simple, Sensitive, and Rapid Detection of FLAG -Tagged,Fusion Proteins 4Genotyping Single Nucleotide Polymorphisms with Molecular Beacons 2Genotyping Single Nucleotide Polymorphisms with Molecular Beacons 3Genotyping Single Nucleotide Polymorphisms with Molecular Beacons 4Genotyping Single Nucleotide Polymorphisms with Molecular Beacons 5Genotyping Single Nucleotide Polymorphisms with Molecular Beacons 6
... LC Sciences provides a unique new tool, ... synthesis serving diverse needs in genomics, proteomics, ... OligoMix is a MIXTURE of a large ... delivered in a single microtube. OligoMix is ...
... 2D is an automated, two-dimensional fractionation system ... Part of Beckman Coulters ProteomeLab family ... in just hours. The system effectively ... cell lysates, addressing a key challenge in ...
... The Excalibur™ mid-, near- and far-infrared ... truly research-grade performance in their class. Yet ... price. Features: Highest-energy throughput: Having ... the source compared to other conventional FT-IRs ...
... Rapid-Screen cDNA Library Panels were designed for ... sets of PCRs to identify the desired ... performed in a 96-well "Master Plate," where ... clones. Having identified the positive well(s) by ...
Biology Products: