Navigation Links
Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population
Date:12/2/2010

RIVERSIDE, Calif. Each year, dengue fever infects as many as 100 million people while yellow fever is responsible for about 30,000 deaths worldwide. Both diseases are spread by infected female Aedes aegypti mosquitoes, which require vertebrate blood to produce eggs. The blood feeding and the egg development are tightly linked to how the mosquito transmits the disease-causing virus.

Now a team of entomologists at the University of California, Riverside has identified a microRNA (a short ribonucleic acid molecule) in female Aedes aegypti mosquitoes that when deactivated disrupts the mosquito's blood digestion and egg development a discovery that could help control the spread of not only dengue and yellow fever but potentially all vector-borne diseases.

MicroRNAs do not code for protein products but play powerful regulatory roles in development and cell growth; their mis-regulation leads to defects, including cancer. The researchers asked if microRNAs were involved in essential functions in female mosquitoes such as blood feeding and egg maturation. These functions are required not only for successful reproduction, but also serve as a foundation for the mosquito's ability to transmit pathogens of devastating human diseases.

In their experiments in the lab, the researchers were screening a number of microRNAs in female Aedes aegypti mosquitoes to study their behavior during blood feeding and reproduction, when they found one microRNA, "miR-275," was highly elevated during egg development.

Next, the researchers developed a method for specific deactivation of miR-275 in Aedes aegypti females and fed these mosquitoes with blood to analyze what effects occur when female mosquitoes no longer have this microRNA at their disposal.

They found that the blood these mosquitoes had fed on remained undigested in their guts. Further, the overall volume of the engorged blood was unusua
'/>"/>

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Strange discovery: Bacteria built with arsenic
2. Mystery dissolves with calcium pump discovery
3. In new novel, secret discovery threatens company and damages love affair
4. New sleep cycle discovery explains why fatty diets during pregnancy make kids obese
5. Gene discovery suggests way to engineer fast-growing plants
6. TB-drugome provides new targets for anti-tuberculosis drug discovery
7. Discovery of an anti-inflammatory substance
8. A discovery could be important for the therapy of lymphoma and leukemia
9. AACR announces new journal, Cancer Discovery
10. Swan song of space shuttle Discovery to carry 2 payloads built by CU-Boulder
11. Discovery of taste receptors in the lungs could help people with asthma breathe easier
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population
(Date:7/30/2014)... could be as simple as inserting a medicated, disappearing ... Washington bioengineers have discovered a potentially faster way to ... HIV. Their method spins the drug into silk-like fibers ... higher doses of the drug than possible with other ... could offer women a potentially more effective, discreet way ...
(Date:7/30/2014)... out how to create colors, nature had already perfected ... many different hues, for example. Now scientists are tapping ... way to make colored plastics. Their paper on using ... rather than dyes, to produce color appears in ... Asger Mortensen, Anders Kristensen and colleagues point out that ...
(Date:7/30/2014)... Monash University Professor Steven Chown has been awarded ... Medal for Excellence in Antarctic Research. , SCAR, ... coordinates high quality international scientific research in the ... Antarctic region in the Earth system. The organisation ... Antarctic Treaty System, responsible for governing the region. ...
Breaking Biology News(10 mins):Dissolvable fabric loaded with medicine might offer faster protection against HIV 2Dissolvable fabric loaded with medicine might offer faster protection against HIV 3
... SANTA CRUZ, CA--Studies conducted in California and elsewhere ... a tool for managing fisheries and protecting marine habitats, ... Cruz. A recent study in the Gulf ... key concept behind marine reserves--the idea that offspring produced ...
... For parents of children with cancer, the hopeful ... for decades. Among the bad newstreatments that enable survival ... cancer who have reached puberty currently have an opportunity ... may have their semen frozen and preserved in sperm ...
... David Queller and Joan Strassmann argue in a new paper ... genetic level on up, give a living thing its "organismality," ... or a colony. Some of the traits scientists ... membership in the same species, may not be necessary to ...
Cached Biology News:Studies show marine reserves can be an effective tool for managing fisheries 2Studies show marine reserves can be an effective tool for managing fisheries 3Studies show marine reserves can be an effective tool for managing fisheries 4Studies show marine reserves can be an effective tool for managing fisheries 5For young boys with cancer, testicular tissue banking may be option to preserve fertility 2For young boys with cancer, testicular tissue banking may be option to preserve fertility 3What is the meaning of 'one'? 2What is the meaning of 'one'? 3
(Date:7/30/2014)... Mass. , July 30, 2014 /PRNewswire/ ... ), a biotechnology company focused on discovering, ... unmet medical needs using RNA-targeted technologies, today ... (RXI-109-1402) with RXI-109, for the reduction of ... revision surgery, has been initiated. ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 Adding to ... weighing boat special – Buy 2 of ... This promotion will benefit lab technicians looking for durable ... boats are ideal for multiple applications including weighing liquids, ... variety of choices including diamond-shaped, hexagonal, square, aluminum weighing, ...
(Date:7/29/2014)... 30, 2014 “PharmaSphere: Emerging Biotech ... Venture Capital Funding” report provides in-depth analysis of ... equity and venture capital segments of the financial ... to have significant impact on the future of ... Furthermore, the report identifies regions of the world ...
(Date:7/29/2014)... Calif. , July 29, 2014 Human ... and therapeutic company focused on extending the healthy, high ... Franz Och , Ph.D., an expert in machine ... Scientist. Och comes to HLI from Google where he ... Translate. He will report directly to HLI Co-Founder and ...
Breaking Biology Technology:RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 2RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 3RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 4RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 5Weighing Boat Promotion Now Available at Pipette.com, Major Pipette Distributor 2Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 2Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 3Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 4Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 2Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 3
... Focus on Business, NEW YORK, March 4 ... of ExaStore Clustered NAS 2008,designed to meet the most ... environments., "Organizations have seen exponential growth in data ... Arnon Gat, Exanet,President & CEO. "ExaStore 2008 has been ...
... MINO(R) Set to Dramatically Improve Airway Inflammatory Disease ... through Personalized Inflammation Control, NEW PROVIDENCE, N.J., March ... NIOX MINO (http://www.nioxmino.com ), a,hand- held point-of-care device ... by the U.S. Food and Drug Administration (FDA).,Physicians in ...
... - Enerkem today announced progress on,the construction of ... ethanol., The Enerkem plant in Westbury, Canada ... world to make cellulosic ethanol at an industrial ... ethanol from creosoted urban wood,(end-of-life cycle power poles). ...
Cached Biology Technology:Exanet Announces ExaStore 2008 Clustered NAS System 2FDA Grants Market Clearance to Aerocrine Inc.'s NIOX MINO(R): a New Hand-Held Device to Measure Airway Inflammation in Asthma 2FDA Grants Market Clearance to Aerocrine Inc.'s NIOX MINO(R): a New Hand-Held Device to Measure Airway Inflammation in Asthma 3FDA Grants Market Clearance to Aerocrine Inc.'s NIOX MINO(R): a New Hand-Held Device to Measure Airway Inflammation in Asthma 4Enerkem announces progress on construction of Canada's first cellulosic ethanol plant 2
... a protein ribonuclease inhibitor that noncovalently binds and ... is seen with RNase 1, T1, T2, H, ... human placental ribonuclease inhibitor in that it has ... not release active RNase in the absence of ...
... ChIP (Chemical Inkjet Printer) is a ... Fingerprinting and Protein Macroarray Analysis, developed ... ProteomeSystems. The strategy compliments established protocols ... (using the proteins isoelectric point and ...
... The BIOLASE Core Kit ... to perform polymerase assays on ... templates. In addition to dNTPs, ... on our widely used BIOLASE ...
Canine Aortic Smooth Muscle Cells (CnAOSMC) (>500,000 cells)...
Biology Products: