Navigation Links
Discovered a genetic biomarker that detects Lewy body dementia
Date:7/26/2013

The Germans Trias i Pujol Health Sciences Research Institute (IGTP) and the Universitat Autnoma de Barcelona (UAB) have discovered the first genetic biomarker to detect Lewy body dementia (LBD), a disease that can be confused with Alzheimer's. This biomarker is found in 20% of cases and differentiates one of the sub-groups of the pathology. Licensed to the Grifols company, it will lead to more precise diagnosis and treatment.

Lewy body dementia (LBD) is the second cause of dementia after Alzheimer's disease. The symptoms of both diseases are very similar, since in both cases there is a gradual deterioration in mental capacity, affecting memory, thought processes, behaviour and physical activity. These similarities mean that some patients with LBD are wrongly diagnosed and treated with the usual drugs for Alzheimer's. But this treatment causes adverse reactions in approximately half of these patients, making the disease much worse in some cases.

Currently there is no specific test to diagnose LBD. In practice, various neurological and neuropsychological tests are used to detect the disease and its possible overlap with other disorders, but clinical diagnosis of LBD is not very accurate.

The research, conducted by the IGTP and the UAB, has led to the discovery of the first genetic biomarker, found in 20% of LBD cases, and differentiating between one sub-group of LBD and Alzheimer's disease. "Although this marker only detects a certain number of LBD sufferers, it significantly increases diagnostic sensitivity to the disease and these patients can get an accurate diagnosis and therefore the right treatment", explains Dr Katrin Beyer, head of the research project and belonging to the Group of Structural and Molecular Pathology, Department of Pathology at the Germans Trias Hospital and Institute.

The researchers first detected the marker through a study of post mortem brain samples, in which they observed an alteration in the expression of the e
'/>"/>

Contact: Maria Jesus Delgado
MariaJesus.Delgado@uab.cat
34-935-814-049
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1 2

Related biology news :

1. Unexpected crustacean diversity discovered in northern freshwater ecosystems
2. University of Alberta led research may have discovered how memories are encoded in our brains
3. Newly discovered foot points to a new kid on the hominin block
4. New immune defense enzyme discovered
5. New genetic mechanism of immune deficiency discovered
6. Housekeeping mechanism for brain stem cells discovered
7. Scientists have discovered genes that increase the risk of osteoporosis and fractures
8. New form of intellectual disability discovered
9. 24 new species of lizards discovered on Caribbean islands are close to extinction
10. Key proteins newly discovered form and function may provide novel cancer treatment target
11. Global warming refuge discovered near at-risk Pacific island nation of Kiribati
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 15, 2014 Research and Markets ( http://www.researchandmarkets.com/research/s6qzt5/samsung_galaxy_s5 ... Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology ... http://photos.prnewswire.com/prnh/20130307/600769 Based on a ... introduces for the first time a fingerprint sensor in ...
(Date:12/17/2014)... Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ) has announced the ... report to their offering. ... in this market is the increasing demand for medical ... of patient data for quick and correct diagnosis during ...
(Date:12/11/2014)... and Markets , http://photos.prnewswire.com/prnh/20130307/600769 ... the addition of the "Biometrics Market in India ... One major trend emerging in this market is the ... more than one characteristic of an individual for verification ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... decrease in yield and an increase in the concentration of ... with the results of previous studies which have shown a ... seeds in high ozone, these results (to be presented at ... on 29th June 2009) could signal a significant income loss ...
... serious demands for the organism, and this is true even ... the ancestors of present marine mammals initiated their return to ... new medium. Dr. Michael Berenbrink and his colleagues at Liverpool ... delivering oxygen to the muscles during locomotion, has been modified ...
... SALT LAKE CITY, June 29, ... use computers and may let amputees control bionic limbs. But existing devices ... Utah study shows that brain signals controlling arm movements can be detected ... it. ...
Cached Biology News:Natural-born divers and the molecular traces of evolution 2Reading the brain without poking it 2Reading the brain without poking it 3Reading the brain without poking it 4Reading the brain without poking it 5
(Date:1/22/2015)... 2015 Dr. Greg Leyer of UAS Labs ... Natural Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... continuing education conference for health care professionals. This year’s pre-conference ... of probiotics in health. Dr. Leyer spoke about the emerging ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Selexis SA, ... mammalian Research Cell Banks (RCBs) used for drug discovery ... Cell Banks will include Next-Generation Sequencing (NGS) ... architecture de-risks biologic manufacturing by ensuring the integrity of ...
(Date:1/22/2015)... , Nueva Jersey , 22 de enero de ... Biomedical Research abre hoy su llamada a nominaciones para ... investigación científica ha hecho, o tiene el potencial para ... humana. Las nominaciones se aceptarán hasta el 15 de ...
(Date:1/22/2015)... , Jan. 22. 2015  Varian Medical Systems (NYSE: ... has been honored for its commitment to sustainability with inclusion ... Varian is the highest ranked healthcare equipment company among the ... during the World Economic Forum at Davos, Switzerland ...
Breaking Biology Technology:Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Varian Honored Among World's 100 Most Sustainable Corporations 2
... 2011 Optimer Pharmaceuticals, Inc. (Nasdaq: OPTR ... financial results after the NASDAQ Global Market closes on ... that day at 5:00 p.m. Eastern Time (2:00 p.m. ... for the third quarter as well as provide a ...
... 2011 At the eighth annual Indiana Life Sciences ... the founder of Bloomington-based Cook Group and one of ... M. Watanabe Life Sciences Champion of the Year award.  ... a tribute to his friend and colleague. ...
... BOSTON, Oct. 26, 2011 13 leading industry speakers will ... Electronic Trial Master Files on November 14-15, 2011 in ... educational exploration of the major shift taking place in the ... Often called the heart of a clinical ...
Cached Biology Technology:Optimer Pharmaceuticals to Host Conference Call and Webcast to Discuss Third Quarter 2011 Financial Results 2BioCrossroads Awards Indiana Life Sciences Leaders 2BioCrossroads Awards Indiana Life Sciences Leaders 3BioCrossroads Awards Indiana Life Sciences Leaders 4
The AVR9-8 stream-select valve is a 9-port, 8-position valve for use with the BioLogic DuoFlow system. This valve is used for high-pressure stream selection....
... Versatile stain for staining RNA (bluish-purple), DNA (blue), proteins ... TLC ≥ 90 % Cation traces: Ca ≤ 10 ... Cr ≤ 5 mg/kg Cu ≤ 5 mg/kg Fe ... 5 mg/kg Mn ≤ 5 mg/kg Na ≤ 50 ...
... Biometras Tpersonal thermocycler provides maximum performance ... generation of Peltier elements, high heating and ... to short run times. With a maximum ... Tpersonal provides half the capacity of much ...
... One-Step Deparaffinization Solution is available ... is an easy-to-use reagent for dewaxing ... immunohistochemistry, in situ hybridization, or other ... paraffin removal consists of dipping the ...
Biology Products: