Navigation Links
Diabetes Research Institute develops oxygen-generating biomaterial
Date:3/1/2012

Miami, FL March 1, 2012 -- Scientists at the Diabetes Research Institute have developed a revolutionary technique to provide critical oxygen for maintaining the survival of insulin-producing cells. This is the first time that scientists have been able to successfully deliver oxygen locally to beta cells using a biomaterial. The results of the study, which represents a major step toward the goal of developing an alternative site to house insulin-producing cells, were just published in the prestigious journal Proceedings of the National Academy of Sciences (PNAS).

One of the major problems with the transplantation of cells, particularly beta cells, is meeting the high nutrient demand of these cells following transplantation. During the initial days of implantation, these cells do not have a functioning vascular network feeding oxygen to the cells, thus cells become starved and large cell loss occurs.

The DRI team, led by Dr. Cherie Stabler, developed a novel oxygen-generating material (termed PDMS-CaO2), which has the capacity to generate this critical element when exposed to water. This spontaneous generation of oxygen creates a nutrient-rich environment with sustained oxygen supplementation for more than six weeks. With this unique biomaterial system, the duration and amount of oxygen generated can be elegantly controlled, thereby providing the ideal environment for the cells. The potential of this technique to enhance beta cell survival with the use of this material was illustrated by incubating beta cells and islets in conditions that mimic the native pancreas.

"We have been working to create an optimal environment for housing transplanted islets that mimics the native pancreas, akin to a 'mini organ,' and this study represents a significant step toward that goal," says Dr. Cherie Stabler. "This oxygen-generating biomaterial provides the supplemental oxygen needed by the islets and serves as a bridge until the vascular bed (blo
'/>"/>

Contact: Lori Weintraub
Lweintraub@drif.org
954-964-4040
Diabetes Research Institute Foundation
Source:Eurekalert

Page: 1 2

Related biology news :

1. VTT searches for novel biomarkers and targets for preventing or treating Type 2 diabetes
2. Diabetes risk factors in young Sri Lankans much higher than previously thought
3. Largest-ever gene study of Type 2 diabetes finds variants across many ethnic groups
4. Body clock receptor linked to diabetes in new genetic study
5. Genetic regulation of metabolomic biomarkers - paths to cardiovascular diseases and type 2 diabetes
6. La Jolla Institute scientist takes quest to conquer Type 1 diabetes to the next level
7. La Jolla Institute researchers identify pivotal immune cell in Type 1 diabetes in humans
8. UCSF, Sanofi collaborate to find new diabetes cures
9. How poor maternal diet can increase risk of diabetes -- new mechanism discovered
10. How poor maternal diet can increase risk of diabetes - new mechanism discovered
11. Study finds air pollution linked to diabetes and hypertension in African-American women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... a new test that can distinguish between birds that ... influenza virus or "bird flu" with those that have ... in the fight against this often fatal strain of ... of South East Asia, particularly Indonesia and Vietnam. , ... to humans and the threat of a pandemic if ...
(Date:10/31/2014)... , Oct. 30, 2014  HITLAB SM ... pleased to announce its inaugural HITLAB Innovators Summit ... University,s Low Library. HITLAB will partner with the ... Wellness, Blueprint Health, ProtoHack, Columbia Business School Alumni ... and Columbia Industrial Engineering and Operations Research, bringing ...
(Date:10/30/2014)... a $1.04 million grant from the U.S. Army ... osteoarthritis using a patient,s own stem cells, spurred ... polymers., Liping Tang, a bioengineering professor and interim ... is primarily focused on helping soldiers who are ... if we inject microscaffolding that we,ve developed into ...
Breaking Biology News(10 mins):New step towards eradication of H5N1 bird flu 2HITLAB Announces Inaugural HITLAB Innovators Summit 2HITLAB Announces Inaugural HITLAB Innovators Summit 3UTA researcher uses microscaffolding injections to mend cartilage, prevent osteoarthritis 2
... medication robbed Elma Phifer of her vision two decades ago ... reduced the ability of her eyes to soothe their damaged ... family and friends to help her do many of the ... twenty years and several life milestones later, Elma is able ...
... share a genetic profile that appears to be unique ... researchers at Cincinnati Children's Hospital Medical Center. The discovery ... specifically tailored to children who suffer from the severest ... Feb. 10 issue of the Journal of Allergy and ...
... throw a wrench in the transmissions of several speed demons ... Medicine in St. Louis and Harvard University have identified a ... slow cell invasion by malaria and other parasites known as ... March 15 issue of Proceedings of the National Academy of ...
Cached Biology News:Artifical cornea lets woman blind 20 years see 2Artifical cornea lets woman blind 20 years see 3Artifical cornea lets woman blind 20 years see 4Asthma gene clusters identified 2Asthma gene clusters identified 3Protein offers way to stop microscopic parasites in their tracks 2Protein offers way to stop microscopic parasites in their tracks 3
(Date:10/30/2014)... Global polyvinyl chloride (PVC) demand registered a ... 2008-2009, especially in North America and Europe. However, the ... to a growing trend. , The largest chunk of ... construction segment. In 2013, the key PVC application spheres ... rigid film. Moreover, the PVC was consumed in the ...
(Date:10/30/2014)... October 30, 2014 SoundConnect ... provider, offers Office 365 end users the key ... complete phone system by adding voice enablement and ... includes Lync Online, a communication tool that includes ... With hosted voice, O365 becomes a comprehensive unified ...
(Date:10/30/2014)... 2014 Spartan Bioscience announced today that ... System . It detects CYP2C19 genetic mutations in less ... The Spartan RX CYP2C19 System is the first near-patient ... in Canada. Due to the system’s ease of use, ... by healthcare professionals such as doctors, nurses, pharmacists, and ...
(Date:10/30/2014)... Ras Al Khaimah, UAE (PRWEB) October 30, 2014 ... the appointment of Dr. James A. Manganello, Chairman of the ... (NSCEC) of The Bahamas. The appointment was made by ... The Bahamas on September 24th, 2014. , More ... Cell Therapy and Research Bill , Prime Minister Perry Christie ...
Breaking Biology Technology:Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 2Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 3SoundConnect Launches Voice Enablement and Hybrid Audio Conferencing for Office 365 2SoundConnect Launches Voice Enablement and Hybrid Audio Conferencing for Office 365 3Health Canada approves first near-patient DNA test for personalized medicine 2Health Canada approves first near-patient DNA test for personalized medicine 3Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3
... (EMBL) discovered a new way to make use of drugs, ... how similar the side effects of different drugs are and ... molecule. The study, published in Science this week, ... often share target proteins, modes of action and unpleasant side ...
... ATRC ), a medical device company and a leader ... the second,quarter ended June 30, 2008 on Tuesday, August 5, ... a.m. ET on Tuesday,August 5, 2008 to discuss second quarter ... be available online from the investor relations,page of AtriCure,s corporate ...
... increased 38% to $42.3 million ... income rose 30% to $14.2 million, SHANGHAI, ... Board: CHBT) ("China-Biotics", "the,Company"), a leading Chinese firm ... of probiotics products,today announced its financial results for ...
Cached Biology Technology:Teaching old drugs new tricks 2AtriCure Announces Web Cast and Conference Call of Second Quarter 2008 Financial Results 2China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 2China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 3China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 4China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 5China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 6China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 7China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 8China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 9China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 10China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 11China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 12China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2008 Financial Results 13
... low temperature freezers offer a superior ... of biological samples with high capacities. ... inner doors ensure excellent warming protection ... ,Application oriented accessories simplify tracking of ...
...
Verotoxin IIbeta (457)...
... Universal Vacuum System UVS400 is a multi-tasking ... UVS400 combines a refrigerated vapor trap and ... single integrated unit. The easy-to-use, wide-mouth glass ... into single jar for easy disposal. The ...
Biology Products: