Navigation Links
Defining gene's role may lead to prevention of dangerous corn toxin
Date:3/25/2008

WEST LAFAYETTE, Ind. - Discovery that a specific gene is integral to both fungal invasion of corn and development of a potentially deadly toxin in the kernels may lead to ways to control the pathogen and the poison.

Purdue University researchers evaluated the fungal gene ZFR1 and found that it is vital to the process of the fungus growing on corn kernels. Production of the toxin decreased when the scientists disabled the gene.

At certain levels, the toxin can cause illness in humans and most domestic livestock. Horses and pigs are at particular risk and can develop fatal diseases by ingesting feed containing one of a group of toxins called fumonisins (few-mahn-ah-sins). About $40 million of the U.S. corn crop is lost annually due to presence of these toxins, according to experts.

"Our main research question has been what triggers toxin production when the fungus attacks the corn kernel; it appears that kernel starch plays an important role," said Charles Woloshuk, a Purdue plant pathologist. "When ZFR1 is deleted, the resulting mutant fungus has a problem transporting sugars that are produced from the degradation of kernel starch."

The resulting sugars must be transported to cells as fuel for other biochemical processes.

"The pathogen - the fungus Fusarium verticillioides - has a number of putative sugar transporter genes that are expressed during its growth on kernels and toxin production," Woloshuk said. "Disruption of ZFR1 also affects expression of the sugar transporter genes."

Woloshuk and his colleague, Bert Bluhm, now at the University of Arkansas, report in the current issue of Molecular Plant Pathology that when the gene ZFR1 is turned off, it reduces manifestation of genes involved in production of the most prevalent and dangerous fumonisin, FB1.

The researchers studied ZFR1 regulation of fungal growth and toxin production in the starch-rich areas of corn kernels and the conversion
'/>"/>

Contact: Susan A. Steeves
ssteeves@purdue.edu
765-496-7481
Purdue University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Gene regulation, not just genes, is what sets humans apart
2. Interaction of just 2 genes governs coloration patterns in mice
3. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
4. Study finds blocking angiogenesis signaling from inside cell may lead to serious health problems
5. Smoking turns on genes -- permanently
6. Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring
7. Hebrew SeniorLife researchers search for aging, osteoporosis genes
8. UT Southwestern researchers identify hundreds of genes controlling female fertility
9. Genes and environment grant funds close look at nature-nurture overlap in common diseases
10. Jumping genes could make for safer gene delivery system
11. Genes from the father facilitate the formation of new species
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Defining gene's role may lead to prevention of dangerous corn toxin
(Date:9/22/2014)... have shown that after a long stay in the ... microbe species remain behind in patients, intestines. The team ... become deadly when provoked by conditions that mimic the ... in mBio , the online open-access journal of ... monitoring and treatment of ICU patients who can develop ...
(Date:9/22/2014)... ATLANTA September 23, 2014 A new American ... Supplemental Nutrition Assistance Program (SNAP), previously known as ... scores compared with income eligible non-participants. The authors ... programs aimed at enhancing the dietary quality of ... assist low-income individuals and households with the resources ...
(Date:9/22/2014)... species have vanished from tropical islands because of ... discovered how fossils can be used to restore ... organic materials found in fossil bones, which contain ... a new study available online and in the ... . Pre-human island ecosystems provide vital clues for ...
Breaking Biology News(10 mins):Critically ill ICU patients lose almost all of their gut microbesand the ones left aren't good 2Critically ill ICU patients lose almost all of their gut microbesand the ones left aren't good 3Federal food program puts food on the table, but dietary quality could be improved 2Answer to restoring lost island biodiversity found in fossils 2
... edible crops for biofuels poses a dilemma: Is it ... of an already malnourished population? David Pimentel and his ... problems linked to converting a variety of crops into ... are also economically and environmentally costly and nowhere near ...
... 28, 2009 Mice with increased levels of a natural ... researchers at UT Southwestern Medical Center have found. ... the "weight-loss hormone," leptin, the researchers report. Finding ... as a therapy against obesity, said Dr. Masashi Yanagisawa, professor ...
... 27, 2009 Scientists and engineers will face a ... clean water to millions of people caught up in ... engineers said today at a briefing at the Broadcast ... Report on the American Chemical Society,s Global Challenges/Chemistry Solutions. ...
Cached Biology News:Biofuels ignite food crisis debate 2Natural brain substance blocks weight gain in mice, UT Southwestern researchers discover 2Substantial work ahead for water issues, say scientists at ACS' Final Report briefing 2Substantial work ahead for water issues, say scientists at ACS' Final Report briefing 3
(Date:9/23/2014)... Texas Fertility Center (TFC) announces the opening ... a Central Texas footprint that includes Round Rock, Central ... for the region’s most established practice will provide full ... Buda, Kyle and San Marcos communities. , “We ... to individuals and couples living in and around South ...
(Date:9/23/2014)... NY (PRWEB) September 23, 2014 Marktech ... of deep ultra violet emitters in the 280 nm ... standard UV emitters which range from 280nm to 405nm. ... and water sanitation as well as curing. Mark Campito, ... line of special interest to manufacturers is that we ...
(Date:9/23/2014)... SC (PRWEB) September 23, 2014 Dr. ... my third book on healthcare offers a three phase ... 21st century healthcare delivery system that would go far ... state’s responsibility regarding the delivery of healthcare.” , “Every ... safety has failed to provide discernable progress throughout that ...
(Date:9/23/2014)... 2014 Healthcare professionals, patients ... convene at the Society for Integrative Oncology ... October 26-28 in Houston, Texas to discuss ... in individualized integrative cancer care. This multi-disciplinary ... nutritionists, naturopaths, acupuncturists, and other complementary care ...
Breaking Biology Technology:Opening Doors to a Family: Texas Fertility Center Announces Newest Fertility Clinic in South Austin 2Opening Doors to a Family: Texas Fertility Center Announces Newest Fertility Clinic in South Austin 3Marktech Introduces its New Line of Deep UV Emitters 2Dr. Ira Williams Offers the Healthcare Solution Necessary for Patient Safety Improvement 2International Medical Experts to Discuss Latest Integrative Oncology Research and Its Translation to Personalized Clinical Care at 11th International Conference of SIO 2International Medical Experts to Discuss Latest Integrative Oncology Research and Its Translation to Personalized Clinical Care at 11th International Conference of SIO 3
... (NYSE: SPW ) today announced that it ... leading engineering company supplying processing solutions for the food ... New Zealand. Terms of the acquisition were not disclosed. ... in the New Zealand dairy, beverage and bio-tech markets, ...
... advisory committee recommended today that the Food and Drug ... US as a once-daily long-term maintenance bronchodilator treatment of ... (COPD), including chronic bronchitis and/or emphysema. ... recommending approval of the 75 mcg dose. The advisory ...
... In addition to reliable high efficiency transfection reagents, ... development of the Reagent Agent(SM) - a new online ... of any nucleic acid into any cell type, including ... based on extensive in-house transfection and electroporation data, customer ...
Cached Biology Technology:SPX Announces Acquisition of B.W. Murdoch Ltd, Broadening Process Engineering and Project Management Capabilities in New Zealand and the Asia Pacific Region 2FDA Advisory Committee Recommends US Approval of Novartis Once-daily Bronchodilator QAB149 for COPD 2FDA Advisory Committee Recommends US Approval of Novartis Once-daily Bronchodilator QAB149 for COPD 3FDA Advisory Committee Recommends US Approval of Novartis Once-daily Bronchodilator QAB149 for COPD 4Reagent Agent(SM) Transfection Cell Line Database From The Transfection Experts 2
Goat polyclonal to ORC2L ( Abpromise for all tested applications). entrezGeneID: 4999 SwissProtID: Q13416...
CD45/CD34 combination 50 tests...
14-3-3 tau Antibody Shipping Temperature: HOT Storage Temperature: -20C...
XPC Immunogen: XPC (NP_004619, 141 a.a. ~ 251 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Biology Products: