Navigation Links
DNA variants may influence COPD patients' response to inhaled bronchodilators
Date:10/25/2013

/p>

Each patient's bronchodilator responsiveness (BDR) was determined by three measures: absolute change in the volume of air exhaled during a forced breath in one second (FEV1); change as a percentage of predicted FEV1; and change as percentage of baseline FEV1.

In the presentation today, Dr. Hardin reported the top SNPs that thus far have been associated with each BDR outcome, but emphasized that additional analysis may reveal other SNPs with equally or greater influence on COPD patients' response.

SNPs in HS6ST3 were associated with the baseline measure while SNPs in XKR4 were associated with baseline and predicted measures. SNPs in the CUBN were associated with absolute and predicted measures. Among African American subjects, SNPs in CDH13 were significantly associated with the absolute measure.


'/>"/>

Contact: Cathy Yarbrough
press@ashg.org
858-243-1814
American Society of Human Genetics
Source:Eurekalert

Page: 1 2

Related biology news :

1. Common genetic variants identify autism risk in high risk siblings of children with ASD
2. Study examines effects of genetic variants for infants with neonatal abstinence syndrome
3. Gene variants may predict who will benefit from breast cancer prevention drugs
4. Penn: New variants at gene linked to kidney disease, sleeping sickness resistance
5. African-American study identifies 4 genetic variants associated with blood pressure
6. New NIH-funded resource focuses on use of genomic variants in medical care
7. Genetic variants associated with bronchodilator responsiveness
8. Circadian rhythms have profound influence on metabolic output, UCI study reveals
9. BUSM researchers identify genes that influence hippocampal volume
10. Fat outside of arteries may influence onset of coronary artery disease
11. New evidence that many genes of small effect influence economic decisions and political attitudes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 15, 2014  HITLAB SM announced today its completion ... its adherence to current U.S. Food and Drug Administration ... smart device and smart phone application trials utilizing the ... "HITLAB is determined to improve global healthcare access, ...
(Date:12/17/2014)... , Dec. 16, 2014  Automation is fundamentally transforming the ... at international borders. Over the past decade, ePassports, biometric ... to self process through border control via eGates and ... of airports, seaports, and land borders across the globe. ...
(Date:12/11/2014)... 09, 2014 Research and Markets , ... ) has announced the addition of the "Biometrics ... One major trend emerging in this ... biometric systems utilize more than one characteristic of an ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... Larry Clark, PhD, Director of the United States Department ... 2013 recipient of the Monell Center,s Kerry-Manheimer Award. The ... of April 29. Since 1976, the annual Kerry-Manheimer ... in the chemosensory sciences. The honoree traditionally spends the ...
... researchers at the University of North Carolina at Chapel ... society,s predominant environmental and health concerns: air pollution. ... and emit isoprene, an abundant molecule in the air ... fluctuations. However, in 2004, researchers, contrary to popular assumptions, ...
... by researcher scar Fernndez-Capetillo at the Spanish National Cancer Research ... photo of the proteins that take part in human DNA ... article, published today in the journal Cell Reports , ... CNIO groups have also participated, including the Proteomics Unit led ...
Cached Biology News:Monell alum Dr. Larry Clark named Center's 2013 Kerry-Manheimer awardee 2Researchers pinpoint how trees play role in smog production 2CNIO researchers 'capture' the replication of the human genome for the first time 2
(Date:1/22/2015)... NJ (PRWEB) January 22, 2015 ... technologies such as the Bioruptor® and complete solutions ... system for chromatin immunoprecipitation, alleviating the need for ... and controls needed for ChIP of histones or ...
(Date:1/22/2015)... , Jan. 22, 2015   Cypher Genomics, Inc., ... Inc. (NASDAQ: SQNM ), the leading ... for next generation noninvasive prenatal tests (NIPT). Through ... technology, called Mantis™, to advance analysis of clinically-relevant ...
(Date:1/22/2015)... 2015   GenoSpace , a precision medicine software company that ... broad use of genomic, imaging and other biomedical data in ... Michelle Munson , CEO of Aspera, an IBM Company, to ... http://photos.prnewswire.com/prnh/20150122/170713 "We are pleased to ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 The report ... by Product Type & Provider Type - Global Advancements, ... market with an in-depth analysis and forecasting of revenues. ... spread through 221 pages and in-depth TOC on “Service ...
Breaking Biology Technology:Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4GenoSpace Expands Board with Appointment of Michelle Munson 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4
... - On Sand Hill Road in Menlo Park, Calif., ... talk these days is of a "boomlet" in deal-making. Technology ... get a meeting with a venture capitalist are now entertaining ... last week that one company, XenSource, had seven solid investment ...
... debates and teaching, it is sometimes useful to go to extremes ... to such tactics, but in the last month exactly that has ... right mind wants to get into a contest with Mother Nature, ... is whether we as students will be bright enough to learn ...
... things can make a professor lose his cool more than ... possibilities for making a mistake are endless: a DVD made ... recordings skipping around uncontrollably or even an overhead projector falling ... the duty of solving such technical issues and more falls ...
Cached Biology Technology:Wisconsin early-stage companies must position themselves to get capital 2Wisconsin early-stage companies must position themselves to get capital 3Planning, reality, good intentions and the road to ... 2Planning, reality, good intentions and the road to ... 3Planning, reality, good intentions and the road to ... 4Interest drives investment of instructional technology 2Interest drives investment of instructional technology 3Interest drives investment of instructional technology 4
Request Info...
, Premium quality synthesis and purification , You provide the sequence, we'll do the rest , Rigorous quality control , Your choice of purification method, amount and format , Available annealed...
, Premium quality synthesis and purification , You provide the sequence, we'll do the rest , Rigorous quality control , Your choice of purification method, amount and format , Available annealed...
... custom siRNA service provides the premium quality ... research. Custom siRNAs can be readily ordered ... target sequence, or by providing the sense ... Ambion's Silencer Validated and ...
Biology Products: