Navigation Links
Crustacean shell with polyester creates mixed-fiber material for nerve repair
Date:6/16/2009

In the clothing industry it's common to mix natural and synthetic fibers. Take cotton and add polyester to make clothing that's soft, breathable and wrinkle free.

Now researchers at the University of Washington are using the same principle for biomedical applications. Mixing chitosan, found in the shells of crabs and shrimp, with an industrial polyester creates a promising new material for the tiny tubes that support repair of a severed nerve, and could serve other medical uses. The hybrid fiber combines the biologically favorable qualities of the natural material with the mechanical strength of the synthetic polymer.

"A nerve guide requires very strict conditions. It needs to be biocompatible, stable in solution, resistant to collapse and also pliable, so that surgeons can suture it to the nerve," said Miqin Zhang, a UW professor of material science and engineering and lead author of a paper now available online in the journal Advanced Materials. "This turns out to be very difficult."

After an injury that severs a peripheral nerve, such as one in a finger, nerve endings continue to grow. But to regain control of the nerve surgeons must join the two fragments. For large gaps surgeons used to attempt a more difficult nerve graft. Current surgical practice is to attach tiny tubes, called nerve guides, that channel the two fragments toward each other.

Today's commercial nerve guides are made from collagen, a structural protein derived from animal cells. But collagen is expensive, the protein tends to trigger an immune response and the material is weak in wet environments, such as those inside the body.

The strength of the nerve guide is important for budding nerve cells.

"This conduit serves as a guide to protect the neuron from injury," Zhang said. "If the tube is made of collagen, it's difficult to keep the conduit open because any stress and it's going to collapse."

Zhang and colleagues dev
'/>"/>

Contact: Hannah Hickey
hickeyh@u.washington.edu
206-543-2580
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Clue to mystery crustacean in parasite form
2. Heavy metal link to mutations, low growth and fertility among crustaceans in Sydney Harbor tributary
3. Resilin springs simplify the control of crustacean limb movements
4. Engineered eggshells to help make hydrogen fuel
5. Shell Provides Consumers Gasoline Industrys First Pay By Touch Technology at the Pump
6. GestureTek/Imagination Launch AirPoint, Worlds First Hand-Tracking Unit, for Shell Group.
7. Underwater microscope helps prevent shellfish poisoning along Gulf Coast of Texas
8. Shell-breaking crabs lived 20 million years earlier than thought
9. Prof. David Kisailus studies engineering and invention on the half-shell
10. Saltwater sleuths: Seeking clues to help determine the ages of fish and shellfish populations
11. Fruit fly helps identify protein critical to eggshell formation that may be pesticide target
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Crustacean shell with polyester creates mixed-fiber material for nerve repair
(Date:4/17/2014)... to treat tuberculosis could be the basis for a ... fungal infections and parasites, yet evade resistance, according to ... , Led by U. of I. chemistry professor Eric ... SQ109 attacks the tuberculosis bacterium, how the drug can ... malaria and how targeting multiple pathways reduces the ...
(Date:4/17/2014)... a word for chili peppers. Information about archaeological remains ... study of the appearance of words for chili peppers ... were domesticated and highlight the value of multi-proxy data ... al.) of nine papers presented in a special feature ... of Sciences on plant and animal domestication edited ...
(Date:4/17/2014)... NJ. April 16, 2014. Kessler Foundation has been ... million from the Department of Defense Spinal Cord ... principal investigator for the randomized, double-blinded, controlled, multi-site ... bone and muscle strength after spinal cord injury. ... & Engineering Research at Kessler Foundation. Two additional ...
Breaking Biology News(10 mins):Multitarget TB drug could treat other diseases, evade resistance 2Chickens to chili peppers 2Chickens to chili peppers 3Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2
... Calif.) Calling the results "extremely surprising," researchers from ... University report that methane gas concentrations in the Gulf ... months after a massive release occurred following the Deepwater ... study, led by oceanographers John Kessler of Texas A&M ...
... team took a significant step forward in understanding ... pollutants and some other gases, except carbon dioxide. ... with some studies suggesting the self-cleaning power of ... changes, while others suggest greater stability. And what ...
... scientists "build" new biological systems, Princeton University scientists have ... the growth of living cells. The team of ... and the scientists showed that they can produce substances ... proteins produced by nature,s own toolkit. "What ...
Cached Biology News:UCSB, Texas A&M scientists find methane gas concentrations have returned to near-normal levels 2NOAA-led team measures atmosphere's self-cleaning capacity 2NOAA-led team measures atmosphere's self-cleaning capacity 3Princeton scientists construct synthetic proteins that sustain life 2Princeton scientists construct synthetic proteins that sustain life 3
(Date:1/15/2014)... Freeslate, Inc ., the leading provider ... Limited, one of India’s top five pharmaceutical companies, has ... for high throughput solid form screening. , ... wide range of quality, affordable generic and branded formulations ...
(Date:1/14/2014)... 2014 Histogen, Inc., a regenerative medicine ... grown under simulated embryonic conditions, today announced that they ... Medical, Inc. for physician-dispensed aesthetic products containing Histogen’s proprietary ... agreement is an amendment to the existing license between ...
(Date:1/14/2014)... Md. , Jan. 14, 2014  Organovo announced today ... the National Institutes of Health (NIH) to help scientists ... treatments to patients on a faster timeline. Organovo is ... (NCATS) and the National Eye Institute (NEI) to develop ...
(Date:1/14/2014)... Ontario , Jan. 14, 2014   Kinaxis ®, provider ... SCM ) and sales and operations planning ( S&OP ) ... Biomanufacturing Summit , which will be held at the ... the conference, join Kinaxis customer Elisabeth Kaszas , Director ...
Breaking Biology Technology:Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... Research Institute (IDRI) announces today the appointment of H. ... new member of the IDRI board of directors.  Parker ... having served as President and CEO of Targeted Genetics ... Corp. "I look forward to working with ...
... FORT WORTH, Texas, Feb. 15, 2011 The Center ... Center recently received a three-year $3.5 million grant ... leader in forensic DNA testing systems, to train researchers ...  This first of its kind accelerated academic certification program ...
... 15, 2011 Neuralstem, Inc. (NYSE Amex: ... I. Westreich to its Board of Directors. With his ... majority of independent directors. (Logo: http://photos.prnewswire.com/prnh/20061221/DCTH007LOGO) ... of Directors and the Company,s Chief Science Officer, welcomed ...
Cached Biology Technology:IDRI Announces Appointment of H. Stewart Parker as Chief Executive Officer 2$3.5 Million Life Technologies Grant Will Help Train, Certify Forensic Scientists at UNT Health Science Center 2$3.5 Million Life Technologies Grant Will Help Train, Certify Forensic Scientists at UNT Health Science Center 3$3.5 Million Life Technologies Grant Will Help Train, Certify Forensic Scientists at UNT Health Science Center 4Former Capital One Director and Business Leader Stanley I. Westreich Joins Neuralstem's Board 2Former Capital One Director and Business Leader Stanley I. Westreich Joins Neuralstem's Board 3
... and temperature-controlled microwave oven for ... Antigen Retrieval of formalin-fixed, paraffin-embedded ... of use, high throughput (96 ... performance. When used in conjunction ...
Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....
...
Experion StdSens chips are the microfluidic chips used to perform standard-sensitivity RNA analysis (nanogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to...
Biology Products: