Navigation Links
Combinations of estrogen-mimicking chemicals found to strongly distort hormone action
Date:3/28/2013

lls that are master regulators of the animals' endocrine systems. Their experiments measured the responses of key signaling pathways that lead to cell proliferation, the secretion of the pituitary hormone prolactin and the activation of proteins involved in apoptosis (programmed cell death), comparing the effects of estradiol alone with those of estradiol and mixtures of bisphenol A, bisphenol S and nonylphenol.

"These compounds work at very low concentrations at the parts per trillion or parts per quadrillion level and when you mix them together they affect estrogenic signaling differently and more dramatically than they do individually," Watson said. "We need to pay attention to this, because estrogens influence so many things in both males and females reproduction, the immune system, metabolism, bone growth, all sorts of important biological functions."

Studies have detected measurable levels of bisphenol A and bisphenol S in the urine of more than 90 percent of Americans. According to Watson, modern humans are exposed to dozens of xenoestrogens more or less continually.

"These things are all over the environment, and we need to know what they do so we can start figuring out what we need to change," Watson said. "They're probably disrupting and confusing hormones in people, and it's important to find a way to prevent that as soon as we can. We need to test these compounds for their hormone-disrupting activities before they are put into products, so we can redesign for safety very early in the process."


'/>"/>
Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2

Related biology news :

1. Cats are able to navigate complex combinations of wet and dry foods to achieve a consistent intake of protein, fat and carbohydrate
2. Yale Study links common chemicals to osteoarthritis
3. Numerical study suggests subsea injection of chemicals didnt prevent oil from rising to sea surface
4. Chemicals today, drugs tomorrow: U-Ms new Center for Drug Discovery
5. Hearing the telltale sounds of dangerous chemicals
6. Hormone-mimicking chemicals cause inter-species mating
7. Production of chemicals without petroleum
8. Effect of chronic exposure to chemicals used as weapons, pesticides under study
9. Brain & Behavior Research Foundation announces spring 2013 conference & free webinars
10. Brain & Behavior Research Foundation awards nearly $4 million in new NARSAD grants
11. Origins of human teamwork found in chimpanzees
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/12/2014)... GARDENS, Fla. , Nov. 12, 2014 ... announced today that its U.are.U ® fingerprint readers ... bakery chain in Central Mexico . ... June 2014 to eliminate payroll issues caused by employees ... to installing the U.are.U fingerprint readers, Montparnasse relied on ...
(Date:11/7/2014)... Debra Auguste, associate professor, biomedical engineering, in the ... of New York, have identified a molecule that ... the most aggressive forms of breast cancer. , ... mortality rate owing to aggressive proliferation and metastasis ... Professor Auguste,s team, discovered the overexpression of intercellular ...
(Date:11/6/2014)... A groundbreaking paper from a team of Florida State ... how plants could adapt to and survive environmental swings ... in the latest issue of the journal The ... complex of DNA and proteins) is organized in a ... some genes are turned on and others are turned ...
Breaking Biology News(10 mins):Montparnasse Pasteleria Achieves Time and Attendance Transparency with Crossmatch U.are.U Fingerprint Readers 2Maize analysis yields whole new world of genetic science 2
... of vertebrates sometimes assist a more dominant pair by ... has been shown to occur among subordinate female cichlids. ... ONE , Dik Heg and colleagues at the University ... that rather than engaging in an act of reciprocal ...
... Norman Ellstrand , a professor of genetics in UC ... been elected as one of this year,s four Botanical ... The BSA Merit Award is the society,s highest honor, ... scientists in plant biology. Some past Merit Award recipients have ...
... Princeton University,s third Art of Science competition will go live ... allows members of the public to choose their favorite 2009 ... time. The juried show features 48 works chosen from ... found here: www.princeton.edu/artofscience/2009 The theme of ...
Cached Biology News:The importance of being helpful -- Cooperative cichlids boost their own reproductive success 2UC Riverside geneticist receives highest honor from Botanical Society of America 2Exhibition showcases the 'art of science' 2Exhibition showcases the 'art of science' 3
(Date:11/26/2014)... (PRWEB) November 26, 2014 On January, ... the Baltimore and Washington D.C. science community to the ... The event, sponsored by the Protein Society, will take ... University Center, Room 312. Through discussion, presentations and ... structural importance of proteins, their role in the industry ...
(Date:11/26/2014)... Silicon Valley Electronic Data Capture (EDC) provider ... , provider of clinical research and data management services ... to its CRO Partnership Program, Clinovo expands ClinCapture ... , “We have found Clinovo’s ClinCapture to exceed ... which is both user friendly and easy to deploy. ...
(Date:11/26/2014)... November 26, 2014 SoundConnect , ... is proud to announce that Darren Suders has joined ... Darren will drive the partner program ... experience. , Darren brings more than 10-years ... key roles in channel operations, from policy development, to ...
(Date:11/26/2014)... , 25 novembre 2014 /PRNewswrie/ -- Theravalues Corporation annuncia ... mercato europeo in occasione di Hi Europe 2014 (dal ... Si tratta della curcumina con la maggiore ... (senza cristalli) e ingredienti approvati dalle norme europee. ... spezia della pianta curcumina ( Curcuma longa ) che ...
Breaking Biology Technology:RPM Alliance Joins Clinovo’s CRO Partnership Program, Further Strengthening Its Presence in Southern California and India 2SoundConnect Appoints Director of Channel Development & Sales 2La curcumina con la maggiore biodisponibilità di sempre farà il suo debutto in Europa 2La curcumina con la maggiore biodisponibilità di sempre farà il suo debutto in Europa 3
... ("Dyadic") (OTC Pink: DYAI), a global biotechnology company focused ... and protein products for the industrial enzyme, bioenergy, and ... FibreZyme® G5000, a next generation, high performance ... quality and improve the economics of various pulp and ...
... N.Y., March 13, 2012   Health Care Compliance ... Christi Health System of Wichita, Kansas has realized ... just two months after selecting and implementing COI-SMART, ... disclosure process. (Logo: http://photos.prnewswire.com/prnh/20061010/NYTU194LOGO ...
... 8, 2012 - Researchers in applied physics have cleared ... called metamaterials, that bend light in unusual ways. ... Harvard team has used extremely short and powerful laser ... within a material. Those suspended metal dots are essential ...
Cached Biology Technology:Dyadic International Launches FibreZyme® G5000 High Performance Powder Pulp and Paper Enzyme in Booth #1065 at Tissue World Americas Conference 2Dyadic International Launches FibreZyme® G5000 High Performance Powder Pulp and Paper Enzyme in Booth #1065 at Tissue World Americas Conference 3Conflict of Interest Management System Selected by Via Christi Health 2Conflict of Interest Management System Selected by Via Christi Health 3Metamaterials may advance with new femtosecond laser technique 2
The SmartSpec printer paper is used to record data generated by the SmartSpec Plus spectrophotometer. Supplied as 5 packs....
... arrays have been developed for affinity ... A variety of ProteinChip chemical surfaces ... to their unique biochemical properties. Each ... side-by-side sample comparison, and the chips ...
... Leu-CMK FLISP Assay with SR-101 Labeled ... nm) • Accurately measure serine protease ... permeabilization • B-Bridge's FLISP Kits utilize ... proteases (FLISPs) to measure chymotrypsin-like activity ...
... Spacer Leu-CMK FLISP Assay with FAM-Labeled ... nm) • Accurately measure serine protease ... permeabilization • B-Bridge's FLISP Kits utilize ... proteases (FLISPs) to measure chymotrypsin-like activity ...
Biology Products: