Navigation Links
Columbia University scientist devises new way to more rapidly generate bone tissue
Date:12/15/2008

NEW YORK (Dec. 15, 2008) Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to "grow" bone and other tissues.

The inability to foster angiogenesis a physiological process involving the growth of new blood vessels from pre-existing vessels has been a major roadblock in tissue regeneration. Previous approaches have included the use of angiogenic growth factors and the fabrication of artificial blood vessels. However, there are problems associated with these approaches. Among these problems: artificially fabricated blood vessels do not readily branch out and network with host blood vessels, and blood vessels induced by angiogenic growth factors tend to be immature and "leaky."

To overcome these obstacles, a team of Columbia researchers has co-transplanted hematopoietic and mesenchymal stem/progenitor cells to promote the regeneration of vascularized tissues. What they found was that the tissue regenerated in bone more rapidly than when either type of stem cell was used alone.

The work by Jeremy Mao, DDS, Ph.D., published today in the Public Libraries of Science, takes a new approach: rarely have mesenchymal and hematopoietic cells been delivered in combination for the healing of defects and the treatment of diseases partially due to the separate research communities in which these two cell groups are studied.

"Dr. Mao's research in tissue engineering represents the fruits of interdisciplinary science. His work has relevance for oral health care, as well as many other health care disciplines," said Dr. Ira Lamster, Dean of the Columbia University College of Dental Medicine.

Dr. Mao and colleagues demonstrated that when human mesenchymal stem/progenitor cells were seeded in micropores of 3D calcium phosphate scaffolds, followed by infusion of gel-suspended CD34+ hematopoietic cells, greater vascularization was seen in mice than when mesenchymal cells
'/>"/>

Contact: Alex Lyda
mal2133@columbia.edu
212-305-0820
Columbia University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Salmon smolt survival similar in Columbia and Fraser rivers
2. Similar survival rates for Pacific salmon in Fraser, Columbia Rivers raises new questions
3. Columbia to award 2008 Horwitz Prize to Arthur Horwich & Ulrich Hartl for cellular protein folding
4. Columbia geneticists uncover new gene involved in determining hair texture and density in humans
5. Columbia researchers: Growth of CT scan use may lead to significant public health problem
6. 3 Columbia University Medical Center faculty elected to Institute of Medicine
7. Columbia to award 2007 Horwitz Prize to three generations of teacher-student scientists
8. Queens University Belfast plays leading role in Europe-wide tests for safer food
9. Wii bit of fun at Rice University has serious intent
10. Rice University study finds possible clues to epilepsy, autism
11. World Energy Outlook to be presented at Rice University Dec. 9
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)... 2014 The Parenteral Drug Association (PDA) today confirmed ... speak and at least seven more will participate in the ... Shoreham Hotel in Washington D.C. , Dec. ... significant support from the regulatory agencies in the ... in our effort to help advance the use of metrics ...
(Date:11/11/2014)... Inc., a Chicago -based digital forensics ... of Yaniv Schiff from Senior Computer Forensics ... role as Director, he will lead company efforts to ... provide leadership within the company,s digital forensics practice area.  ... Schiff joined Forensicon in 2006 and has ...
(Date:11/7/2014)... Leading Biometric companies aim to provide ... online transactions.  Companies in focus today are: NXT-ID, Inc. (NASDAQ: ... BABA ), Google Inc. (NASDAQ: GOOG ), Microsoft ... EBAY ) and MasterCard Inc. (NYSE: MA) ... biometric authentication company focused on the growing mobile commerce is ...
Breaking Biology News(10 mins):FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6
... de Barcelona (UAB) has discovered the first scientific evidence of ... ancient Scythian warriors living over 2,000 years ago in the ... now, the results published in PLoS ONE indicate ... of Europeans, but to a demographic expansion of local Central ...
... wild pandas may need new dinner reservations and quickly ... off swaths of bamboo that pandas need to survive. ... , scientists from Michigan State University and the Chinese Academy ... affect the most common species of bamboo that carpet the ...
... Nobody knows the remarkable properties of human skin like ... our skin sensitive, sending the brain precise information about ... preserve a protective barrier against the world. Combining these ... exciting challenge for Stanford Chemical Engineering Professor Zhenan Bao ...
Cached Biology News:Mongolia and the Altai Mountains: Origins of genetic blending between Europeans and Asians 2Mongolia and the Altai Mountains: Origins of genetic blending between Europeans and Asians 3Climate change threatens giant pandas' bamboo buffet and survival 2Touch-sensitive plastic skin heals itself 2Touch-sensitive plastic skin heals itself 3
(Date:11/21/2014)... 2014 Deep Research Report on Global ... and in-depth research report on the Sodium ferrocyanide ... its definition, classification, application, and industry chain structure ... the international market analysis, including China’s domestic market ... Europe, Asia, China, Japan etc. regions) industry analysis ...
(Date:11/21/2014)... SAN DIEGO , Nov. 20, 2014  Cytori Therapeutics ... Marc Hedrick , M.D. will present live at VirtualInvestorConferences.com ... 4, 2014 TIME:    11:15 am PT / 2:15 ... this URL into your browser,s address bar: http://bit.ly/1B2KGaL ... time and receive event updates. This will ...
(Date:11/18/2014)... LA (PRWEB) November 17, 2014 ... build-to-order, open architecture blade-based and rackmount computing infrastructure, ... Tesla® K80 dual-GPU accelerator throughout its GPU-enabled blade ... pair of the company’s latest proprietary 80-lane Gen3 ... eight discrete NVIDIA Tesla K80 dual-GPU accelerator cards ...
(Date:11/18/2014)... American Process Inc. (Atlanta, GA) and ... with researchers at Georgia Institute of Technology, Clark ... USDA’s Forest Products Laboratory to develop ultra-strong, lightweight ... a rapidly emerging high performance nanomaterial extracted from ... replace heavy steel structures within cars, such as ...
Breaking Biology Technology:Sodium Ferrocyanide Market: Analysis for Global & China Regions Development Trends Available at DeepResearchReports.com 2Sodium Ferrocyanide Market: Analysis for Global & China Regions Development Trends Available at DeepResearchReports.com 3Cytori Therapeutics to Provide Corporate Update and Investor Presentation on December 4 through a Live, Interactive Webcast 2Cytori Therapeutics to Provide Corporate Update and Investor Presentation on December 4 through a Live, Interactive Webcast 3Cytori Therapeutics to Provide Corporate Update and Investor Presentation on December 4 through a Live, Interactive Webcast 4Cirrascale® Expands Multi-GPU Peering Solutions with Support for New NVIDIA Tesla K80 Dual-GPU Accelerators 2Cirrascale® Expands Multi-GPU Peering Solutions with Support for New NVIDIA Tesla K80 Dual-GPU Accelerators 3American Process Inc. Announces Partnership to Develop Ultra-Strong, Lightweight Automotive Components Using Nanotechnology from Nature 2American Process Inc. Announces Partnership to Develop Ultra-Strong, Lightweight Automotive Components Using Nanotechnology from Nature 3
... Blacksburg, Va. Researchers at the Virginia Bioinformatics Institute ... guidelines that should help researchers in their efforts to ... The stakes are high: the concept of biological parts ... engineering are to be applied to biology. If successful, ...
... Mass., Aug. 8 Pressure,BioSciences, Inc. (Nasdaq: PBIO ... to discuss its second quarter 2008 financial results and,to ... the,teleconference either by telephone or through a live web-cast. ... Date: Thursday, August 14, 2008, Time: 4:30 p.m. ...
... Aug. 8 MGT Capital Investments,Inc. (Amex: ... the Healthcare,Information Technology ("HCIT") sector, today reported financial ... and provided an update on,strategic milestones., Tim ... through,the first half of 2008 reflect continued progress ...
Cached Biology Technology:Tips on how to build a better home for biological parts 2Tips on how to build a better home for biological parts 3Pressure BioSciences, Inc. to Discuss Second Quarter 2008 Financial Results and Provide Business Update 2MGT Capital Investments Reports Second Quarter 2008 Financial Results and Provides Update on Recent Developments 2MGT Capital Investments Reports Second Quarter 2008 Financial Results and Provides Update on Recent Developments 3MGT Capital Investments Reports Second Quarter 2008 Financial Results and Provides Update on Recent Developments 4MGT Capital Investments Reports Second Quarter 2008 Financial Results and Provides Update on Recent Developments 5
... 48 lanes, 24 bi-directional, of patient DNA ... either slab gel or capillary sequencers, using ... parameters in Explorer have been sealed to ... have built Explorer for ease of use, ...
Molecular Biological Resources offers bulk quantities of existing protein products. Please see the Chimerx divisions website for existing products and contact lloconne@molbiores.com for pricing....
... Quality ISO 9001:2000 Certified USDA Research ... Validated, SOP's Training AALAS Certified ... All Procedures GLP Documentation Upon Request ... shopping point for all your custom immunology ...
... BalanceTalk XL provides balance data collection and ... Complete integration with Microsoft Excel , ... moisture analyzers , New balances can be added ... Collect data from multiple balances into one spreadsheet ...
Biology Products: