Navigation Links
Cleverly designed vaccine blocks H5 avian influenza in models
Date:3/25/2013

ne slowed its function, interfering with the virus' replication. That makes the vaccine safer.

The next step was to engineer the H5 gene into the vaccine. It was inserted into segment 8, where the NS2 gene had been.

Another aspect of the new vaccine's design makes it safer still, by rendering successful reassortment less likely. Both NS1 and NS2 are needed for viral replication. Since the two genes are now separated into different segments, any reassortment will have to include both segments, instead of just segment 8, in order for a reassortant virus to be viable. This greatly reduced the probability of successful reassortment.

The World Health Organization (WHO) recognizes avian influenza subtypes H5, H7, and H9 as potential pandemic viruses, because they all have in rare instances infected humans, and because they circulate in wild birds. Single reassortants could be sufficient to breach the species barrier, and since they do not circulate among us, we lack any immunity. Moreover, H5 is unusually lethal, having killed roughly half of those few it is confirmed to have infected.


'/>"/>

Contact: Garth Hogan
ghogan@asmusa.org
202-942-9389
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related biology news :

1. A new type of data papers designed to publish online interactive keys identifying biodiversity
2. Faster, cheaper gas and liquid separation using custom designed and built mesoscopic structures
3. MIT-designed cooler preserves tuberculosis drugs, records doses
4. Portable diagnostics designed to be shaken, not stirred
5. Research is ensuring stormwater systems are designed for the future
6. HPV vaccine trends point to failures in patient education, vaccine programs
7. Cancer vaccines self-sabotage, channel immune attack to injection site
8. Human trials for Streptococcus A vaccine
9. Novel aptamer boosts T cell-based immune response to therapeutic vaccines
10. Designer bacteria may lead to better vaccines
11. UMMS experts seek better flu vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... addition of the "Global Facial Recognition Market ... http://photos.prnewswire.com/prnh/20130307/600769 Facial ... of individuals. Facial recognition system measures the overall ... jaw edges, mouth, and the distance between eyes. ...
(Date:12/11/2014)... SALEM, N.C. , Dec. 10, 2014  That blood ... for quite a while. Hypertension – the medical term for ... in the early 1800s, and the inflatable cuff that,s used ... That doesn,t, however, mean there,s nothing new about hypertension, its ... some long-held beliefs about the condition and the best ways ...
(Date:12/10/2014)... 9, 2014  Valencell, a leader in performance biometric ... staggering demand from its licensees for highly accurate, clinically ... not solely coming from fitness and health sectors, but ... "A wearable is only as useful as the biometric ... ultimate driver in long-term mass consumer adoption of wearable ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Wearable Technology Products Demand Highly Accurate Biometric Technology 2
... egg question. Where do the infectious protein particles called ... cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, in ... of their properly folded protein counterparts, but they usually ... Biochemists at Emory University School of Medicine have identified ...
... Institute of Molecular and Cell Biology (IMCB) has discovered ... deadly plant toxin Ricin, widely feared for its bioterrorism ... for the tens of thousands of hospital-acquired infections in ... this first ever genome-wide study to understand how the ...
... sometimes have its advantages. That,s according to a study of ... native Chilean forest. The data show that the pollinators those ... of resources found in agricultural lands. As a result, trees ... successfully when separated by resource-poor pine plantations than by those ...
Cached Biology News:Cellular stress can induce yeast to promote prion formation 2A*Star scientists discover how to combat hospital-acquired infections and life-threatening toxins 2A*Star scientists discover how to combat hospital-acquired infections and life-threatening toxins 3As agricultural riches waylay pollinators, an endangered tree suffers 2As agricultural riches waylay pollinators, an endangered tree suffers 3
(Date:12/17/2014)... 17, 2014 Audacity, a leading California-based ... member of the Huntsworth Health Group, is proud to ... team. In her role, Gonzales will serve as Senior ... incredibly honored to welcome a talent of Jamie’s caliber ... Gaëtan Fraikin. “She is a proven healthcare innovation leader ...
(Date:12/17/2014)... 2014  United Therapeutics Corporation (NASDAQ: UTHR ... as changes to Martine Rothblatt , Ph.D,s compensation ... United Therapeutics announced the promotion of Roger ... and David Zaccardelli , Pharm.D. to Executive Vice ... promotions, Dr. Rothblatt,s title will change from Chairman and ...
(Date:12/17/2014)... 17, 2014 Tigercat Pharma, Inc. today ... evaluating the investigational oral NK-1 receptor antagonist VPD-737 ... chronic itch who are unresponsive or inadequately responsive ... steroids and antihistamines. The primary ... Scale (VAS) itch score from baseline, comparing drug ...
(Date:12/15/2014)... (PRWEB) December 15, 2014 METTLER ... inline PVM tool, ParticleView V19 with PVM ... situ probe-based particle vision and measurement tool continuously ... process conditions. ParticleView V19 then automatically prepares a ... tracking particle size and concentration changes. This compelling ...
Breaking Biology Technology:Audacity Welcomes Healthcare Communications Expert Jamie Gonzales as Senior Vice President of Client Services 2United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 2United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 3United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 4Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4New Real-Time In Situ Probe-Based Video Microscope from METTLER TOLEDO 2
... will seek additional venture funding this year in ... president and CEO Loren G. Peterson said. , ,Peterson ... the Innovation Monday program. He said ZyStor, which is ... filing the application for its lead product in early ...
... Wis. - For the second time in six ... giant, claiming patent infringement. , ,This time Hyperphrase Technologies ... Internet search engine company, for allegedly using technology that ... other sites or advertisements. Hyperphrase claims that Google Toolbar ...
... enjoyed another year of impressive growth, according to the ... a quarterly publication on the trademark industry published by ... and online brand monitoring services. , ,The report provides ... trademark filing activity, a ranking of leading trademark law ...
Cached Biology Technology:Milwaukee area biotech ZyStor seeks more funding 2Milwaukee area biotech ZyStor seeks more funding 3
... Costar strip ejector is a unique product ... strips from their holder. Linkage: This CLS ... to easily match Cornings product number. If ... the old Sigma-Aldrich number (Z71,314-7) or contact ...
...
... The ideal modular cleanroom for biological ... that require cleanliness (to Class 10/ISO ... precision-joined to create ultra-smooth surfaces that ... disinfect. One-inch radius corners simplify cleaning. ...
This free-standing work station safely ventilates fumes upwards, away from the work surface. Optional Exhaust Purification System features bonded charcoal filters that remove organic chemical vapors ...
Biology Products: