Navigation Links
Cleverly designed vaccine blocks H5 avian influenza in models
Date:3/25/2013

ne slowed its function, interfering with the virus' replication. That makes the vaccine safer.

The next step was to engineer the H5 gene into the vaccine. It was inserted into segment 8, where the NS2 gene had been.

Another aspect of the new vaccine's design makes it safer still, by rendering successful reassortment less likely. Both NS1 and NS2 are needed for viral replication. Since the two genes are now separated into different segments, any reassortment will have to include both segments, instead of just segment 8, in order for a reassortant virus to be viable. This greatly reduced the probability of successful reassortment.

The World Health Organization (WHO) recognizes avian influenza subtypes H5, H7, and H9 as potential pandemic viruses, because they all have in rare instances infected humans, and because they circulate in wild birds. Single reassortants could be sufficient to breach the species barrier, and since they do not circulate among us, we lack any immunity. Moreover, H5 is unusually lethal, having killed roughly half of those few it is confirmed to have infected.


'/>"/>

Contact: Garth Hogan
ghogan@asmusa.org
202-942-9389
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related biology news :

1. A new type of data papers designed to publish online interactive keys identifying biodiversity
2. Faster, cheaper gas and liquid separation using custom designed and built mesoscopic structures
3. MIT-designed cooler preserves tuberculosis drugs, records doses
4. Portable diagnostics designed to be shaken, not stirred
5. Research is ensuring stormwater systems are designed for the future
6. HPV vaccine trends point to failures in patient education, vaccine programs
7. Cancer vaccines self-sabotage, channel immune attack to injection site
8. Human trials for Streptococcus A vaccine
9. Novel aptamer boosts T cell-based immune response to therapeutic vaccines
10. Designer bacteria may lead to better vaccines
11. UMMS experts seek better flu vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/29/2014)... New research presented at the Society for Integrative ... showed for the first time that it is ... a readily available nutritional supplement, AHCC. ... A. Smith, Pharm.D., associate professor in the Department ... University of Texas Health Science Center at Houston ...
(Date:10/29/2014)... to make their food, but they also need protection from ... a group of molecules in plants that shields them from ... of the American Chemical Society , one team reports on ... Timothy Zwier and colleagues at Purdue University note that the ... serious damage to plant DNA and, as a result, hinder ...
(Date:10/29/2014)... a ceremony held in New York City on September ... the American Cancer Society Professor of Genome Sciences and ... 2008 Honorary Doctor of Philosophy of Tel Aviv University, ... Medical Science. , In addition to her honorary degree ... at the TAU School of Medicine, and for the ...
Breaking Biology News(10 mins):HPV infections in women eradicated by AHCC, Japanese mushroom extract 2Geneticist and humanitarian: Prof. Mary-Claire King receives Lasker Award 2
... , No one is in a better position to monitor ... the people living there. But many scientists believe the ... is simply too great to bridge -- that native peoples ... But now, researchers led by Stanford ecologist Jose Fragoso have ...
... New research from the Universities of Portsmouth and Leicester has ... London as being part of a giant pterosaur ... and toothed animals. Dr David Martill from the University ... Leicester examined the fossil - which consisted of the tip ...
... eyes or legs, yet they are able to "see" and ... is controlled by a series of molecular-level signals between proteins ... The Plant Cell, University of Missouri scientists report ... plays in this molecular signaling pathway that regulates phototropism in ...
Cached Biology News:Can indigenous peoples be relied on to gather reliable environmental data? 2Can indigenous peoples be relied on to gather reliable environmental data? 3Tiny fossil fragment reveals giant-but-ugly-truth 2Tiny fossil fragment reveals giant-but-ugly-truth 3Protein plays role in helping plants see light 2
(Date:10/31/2014)... Brady (NYSE:BRC), a global leader in product and ... testimonial on the effectiveness of its FreezerBondz™ specimen ... the BloodCenter of Wisconsin discusses the challenges she faces ... thousands of samples, and how the durability of Brady’s ... design our label materials with the harsh conditions of ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 The report ... Chemicals), by Application (Cosmetics & Toiletries, and Soaps & ... to 2019”, has defined and segmented the Fragrance Ingredients ... trends in terms of value. The market has been ... North America, Europe, Asia-Pacific, Latin America, and Rest of ...
(Date:10/30/2014)... 30, 2014 On October 26th ... Showcase in Chicago, leading applied stem cell research ... Wade McKenna presented talks on New Techniques for ... Applications For Stem Cells. , Dr. Riordan focused ... the properties of AlphaGEMS that include: wound healing; ...
(Date:10/30/2014)... 30, 2014 Whitehouse Laboratories has formally ... Stability Testing and Package Test Capacity. Responding to growing ... a dramatic increase in environmental chamber storage space that ... and aging samples to be securely held on site ... capital expenditure has already taken place with the recent ...
Breaking Biology Technology:Brady Debuts New Lab Label Testimonial Video 2Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 2Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 3Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 4Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 5Riordan-McKenna Institute Founders, Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna Present at the Mid American Regenerative and Cellular Medicine Showcase 2Riordan-McKenna Institute Founders, Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna Present at the Mid American Regenerative and Cellular Medicine Showcase 3Riordan-McKenna Institute Founders, Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna Present at the Mid American Regenerative and Cellular Medicine Showcase 4Whitehouse Labs Announces Major Capital Investment in Stability and Storage Testing Capacity 2Whitehouse Labs Announces Major Capital Investment in Stability and Storage Testing Capacity 3
... two months ahead of schedule ... -, - Progress continues on LymphoStat-B, ABthrax and TRAIL receptor antibody ... programs - ... ROCKVILLE, Md., Nov. 1 Human Genome Sciences,Inc. (Nasdaq: HGSI ) today announced financial results ...
... CA -- Make way for the real nanopod and ... of researchers with the U.S. Department of Energys Lawrence ... California at Berkeley have created the first fully functional ... by several orders of magnitude the smallest radio ever ...
... - Dragon Pharmaceutical Inc.,(TSX: DDD; OTCBB: DRUG; ... method,for 7ACA production has been successfully implemented ... achievement validates the Company,s research,and development efforts ... bring immediate benefits to production operations by,increasing ...
Cached Biology Technology:Human Genome Sciences Announces Third Quarter 2007 Financial Results and Key Developments 2Human Genome Sciences Announces Third Quarter 2007 Financial Results and Key Developments 3Human Genome Sciences Announces Third Quarter 2007 Financial Results and Key Developments 4Human Genome Sciences Announces Third Quarter 2007 Financial Results and Key Developments 5Human Genome Sciences Announces Third Quarter 2007 Financial Results and Key Developments 6Human Genome Sciences Announces Third Quarter 2007 Financial Results and Key Developments 7Human Genome Sciences Announces Third Quarter 2007 Financial Results and Key Developments 8Human Genome Sciences Announces Third Quarter 2007 Financial Results and Key Developments 9Make way for the real nanopod 2Make way for the real nanopod 3Make way for the real nanopod 4Dragon Announces R&D Achievement in Biotech Manufacturing Process 2Dragon Announces R&D Achievement in Biotech Manufacturing Process 3
IC50: 3 ng/ml · Limit of detection: 0.9 ng/ml...
Request Info...
Image Analysis Software. PC Version of NIH Image....
... the premium quality siRNAs you need for ... be readily ordered online by providing either ... providing the sense and antisense siRNA sequences. ... Silencer Pre-designed siRNAs, which are already designed ...
Biology Products: