Navigation Links
Cleveland Clinic develops clinical screening program for no.1 genetic cause of colon cancer
Date:2/14/2013

Wednesday, February 13, 2013, Cleveland: Cleveland Clinic researchers have found that colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome, the most common hereditary, adult-onset cause of colorectal cancer, as published in the online version of the Journal of Clinical Oncology.

Lynch syndrome is the most common genetic cause of colon cancer in adults. The study found that a universal screening program of all colorectal cancers surgically removed at Cleveland Clinic resulted in increased identification of Lynch syndrome patients by successfully referring individuals whose tumors screen positive to genetics professionals. Identification of Lynch syndrome will lead to significantly improved outcomes for colorectal cancer patients and their family members.

Most colorectal cancers are sporadic, and are not due to inherited genetic causes. More than 140 million Americans are diagnosed with colorectal cancer each year. With one out of 35 colorectal cancer cases resulting from Lynch syndrome, a hereditary condition that predisposes to a wide variety of cancers at earlier ages, a clinical recommendation was established in 2009 to screen all colorectal patients for Lynch syndrome. With four million Americans having Lynch syndrome each year, and most going unrecognized, a systematic manner of screening for this condition presented a challenge. Furthermore, another challenge is ensuring that all individuals whose tumors screen positive for potential Lynch syndrome are referred to genetics professionals.

By identifying Lynch syndrome patients, measures can be taken to thwart the development of additional cancers in the patient, as well as increase surveillance in the patient. Once Lynch syndrome has been identified in a patient, his/her family members can be referred to genetics professionals to determine if they too have inherited the same condition. As patients who carry the Lynch gene un
'/>"/>

Contact: Laura Ambro
ambrol@ccf.org
216-636-5876
Cleveland Clinic
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Cleveland Clinic researchers receive $5 million grant to discover novel pathways to heart disease
2. Collaborative preclinical efficacy studies suggest a new target for drug addiction treatment
3. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
4. New clinical trial explores novel noninvasive colon cancer screening test
5. Genzyme/ACMG Foundation Genetics Training Award in Clinical Biochemical Genetics announced
6. FirstMark Exhibiting at the Inaugural Atlanta Clinical Cardiology Update
7. MedNet Solutions to Demonstrate Its Innovative Suite of eClinical Solutions at the 2012 Bio-IT World Conference & Expo
8. Clinical trial launches to see whether vitamin D helps treat multiple sclerosis
9. AAO-HNS releases updated Clinical Indicators
10. Sequencing works in clinical setting to help -- finally -- get a diagnosis
11. VolitionRX Raises Over $1 Million To Begin Clinical Trials of Blood Based Diagnostic Tests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... DURHAM, N.C. In a cost-effectiveness analysis of commercial ... the drug Qsymia showed the best value for the ... loss, but was also the most expensive option tested, ... Graduate Medical School. , The findings, published in the ... important information on the health and weight-loss benefits per ...
(Date:7/22/2014)... NEW YORK, NY -- As part of a multinational, ... at Mount Sinai have helped identify over 100 locations ... developing schizophrenia, in the largest genomic study published on ... The findings, published online in Nature , point ... and could lead to new approaches to treating the ...
(Date:7/22/2014)... have adapted to New York City,s human behaviour, allowing ... than their fellow squirrels in the woods. , Dr ... & Agriculture, led the study that proved eastern grey ... environments and prevent unnecessary responses when humans acted in ... , "As we rapidly increase the spread of ...
Breaking Biology News(10 mins):Study compares cost-effectiveness of weight-loss programs and drugs 2Study compares cost-effectiveness of weight-loss programs and drugs 3Mount Sinai scientists and international team shed new light on schizophrenia 2Mount Sinai scientists and international team shed new light on schizophrenia 3New York squirrels are nuts about city life 2
... natural coal deposits in the Gulf of Alaska are ... Exxon Valdez tanker catastrophe. This clearly disproves the theory ... environmental damage. PAH pollutants were blamed for the continuing ... Then a dispute erupted over the origins of these ...
... Pasadena, Calif.In a finding that sheds new light on ... the California Institute of Technology (Caltech) have pinpointed the ... The discovery, described in the August 30 ... offer insight into autism and other disorders where social ...
... and some amphibians possess a unique sensory capability in ... to "touch" objects in their surroundings without direct physical ... van Hermmen and his team in the physics department ... basis for this sensory system. What they discover might ...
Cached Biology News:Bioavailable contaminants come from the Exxon Valdez oil catastrophe 2Caltech neuroscientists find brain region responsible for our sense of personal space 2Caltech neuroscientists find brain region responsible for our sense of personal space 3Caltech neuroscientists find brain region responsible for our sense of personal space 4Mathematical keys to a sixth sense -- the lateral-line system 2Mathematical keys to a sixth sense -- the lateral-line system 3Mathematical keys to a sixth sense -- the lateral-line system 4
(Date:7/22/2014)... Albany, New York (PRWEB) July 22, 2014 ... the world. The heat produced by controlled fission chain ... pressure. This steam pressure is used to drive a ... produce approximately 19% of the world’s total electricity production. ... due to several under construction, planned and proposed nuclear ...
(Date:7/22/2014)... Automated cell culture systems are instruments that ... They allow production of optimum cells at a large ... discovery and industries and biopharmaceutical companies. Cell culture automation ... cryobanking, cell-based assays, and cellular expression systems as they ... the Global Cell Culture market will grow ...
(Date:7/22/2014)... 2014 The DNA Spectrum ... visual representation of history, migration, and culture. , ... by family history stories stemming from Europe. His father ... country." Pictures and 8mm home movies painted an elaborate ... family, and Steve ordered a test from DNA Spectrum ...
(Date:7/22/2014)... July 22, 2014 OHAUS Corporation, ... and mechanical balances and scales, proudly announces its ... won Laboratory Equipment magazine’s 2014 “Readers' Choice” Award ... consecutive year the Explorer was voted the best ... Readers’ Choice Awards celebrates “excellence in product design ...
Breaking Biology Technology:Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 2Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 3Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 2Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 3Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 4DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 2DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 3DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 4OHAUS Explorer Voted “Best Balance” in Laboratory Equipment’s 2014 Readers’ Choice Awards 2
... , , , JEFFERSON, N.C., ... give people more confidence to go to work in a pandemic ... products the company developed for the bird flu influenza A subtype ... for the bird flu (H5N1), which never became contagious. The Next ...
... , , SEATTLE, Aug. ... Stephen R. Murray, M.D., Ph.D. as Vice President of ... and protocols at Omeros, and currently is leading the ... include OMS103HP, the Company,s lead candidate being evaluated in ...
... , ... pleased to announce that SK Life Science, Inc. (SKLSI), has licensed Pristima for its Research ... ... a world leader in toxicology and pathology data management solutions and the developer of Pristima™ ...
Cached Biology Technology:Next Safety Releases Advanced Respirator for Infectious Diseases 2Next Safety Releases Advanced Respirator for Infectious Diseases 3Omeros Appoints New Vice President of Clinical Development 2SK Life Sciences has Licensed Pristima 2
... number is a new product ... Cornings product number. If showing ... under the old Sigma-Aldrich number ... for assistance. ID clarifier: filling ...
Extremely high efficiency packaging extracts useful for transfecting our EpiFOS™ or CopyControl™ Fosmids, or any DNA vector with cos sites. A tremendous value when conpared to the competition...
... A simultaneous dual parameter assay ... poly caspase activity. Active caspases are ... peptide inhibitors, which are cell-permeable, non-cytotoxic ... caspases within the cells. At the ...
... in DMEM and harvested at the log phase ... antigens in their native forms, cells were fixed ... a 12-well (5 mm) adhesive coated slide, with ... attachment and to minimize background staining. Each ...
Biology Products: