Navigation Links
Cleveland Clinic develops clinical screening program for no.1 genetic cause of colon cancer
Date:2/14/2013

Wednesday, February 13, 2013, Cleveland: Cleveland Clinic researchers have found that colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome, the most common hereditary, adult-onset cause of colorectal cancer, as published in the online version of the Journal of Clinical Oncology.

Lynch syndrome is the most common genetic cause of colon cancer in adults. The study found that a universal screening program of all colorectal cancers surgically removed at Cleveland Clinic resulted in increased identification of Lynch syndrome patients by successfully referring individuals whose tumors screen positive to genetics professionals. Identification of Lynch syndrome will lead to significantly improved outcomes for colorectal cancer patients and their family members.

Most colorectal cancers are sporadic, and are not due to inherited genetic causes. More than 140 million Americans are diagnosed with colorectal cancer each year. With one out of 35 colorectal cancer cases resulting from Lynch syndrome, a hereditary condition that predisposes to a wide variety of cancers at earlier ages, a clinical recommendation was established in 2009 to screen all colorectal patients for Lynch syndrome. With four million Americans having Lynch syndrome each year, and most going unrecognized, a systematic manner of screening for this condition presented a challenge. Furthermore, another challenge is ensuring that all individuals whose tumors screen positive for potential Lynch syndrome are referred to genetics professionals.

By identifying Lynch syndrome patients, measures can be taken to thwart the development of additional cancers in the patient, as well as increase surveillance in the patient. Once Lynch syndrome has been identified in a patient, his/her family members can be referred to genetics professionals to determine if they too have inherited the same condition. As patients who carry the Lynch gene un
'/>"/>

Contact: Laura Ambro
ambrol@ccf.org
216-636-5876
Cleveland Clinic
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Cleveland Clinic researchers receive $5 million grant to discover novel pathways to heart disease
2. Collaborative preclinical efficacy studies suggest a new target for drug addiction treatment
3. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
4. New clinical trial explores novel noninvasive colon cancer screening test
5. Genzyme/ACMG Foundation Genetics Training Award in Clinical Biochemical Genetics announced
6. FirstMark Exhibiting at the Inaugural Atlanta Clinical Cardiology Update
7. MedNet Solutions to Demonstrate Its Innovative Suite of eClinical Solutions at the 2012 Bio-IT World Conference & Expo
8. Clinical trial launches to see whether vitamin D helps treat multiple sclerosis
9. AAO-HNS releases updated Clinical Indicators
10. Sequencing works in clinical setting to help -- finally -- get a diagnosis
11. VolitionRX Raises Over $1 Million To Begin Clinical Trials of Blood Based Diagnostic Tests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... NEW YORK , Dec. 23, 2014  Since its launch in ... of people to eliminate the pain of trying to remember ... their own biometrics fused to their smartphones. To assist people ... Labs , the company that created 1U and focuses on ...
(Date:12/19/2014)... Dec. 18, 2014 Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ... Monitor: North America Perimeter Security Systems Market" report to ... The North American perimeter security market is estimated to ... Although the U.S. market holds a larger share in this ...
(Date:12/17/2014)... SM announced today its completion of a Good ... current U.S. Food and Drug Administration (FDA) regulations. This ... smart phone application trials utilizing the highest principles for ... determined to improve global healthcare access, quality, and delivery ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... of externally-shelled cephalopods that thrived in the tropical ... intervening years their modern soft bodied relatives dumped ... which makes Nautilus ideally suited to discover the ... the complex coleoid [soft bodied cephalopod] brains say ...
... Airplanes, submarines and even automobiles of tomorrow ... gyroscopes for navigation and other purposes. The proprietary system ... consisting of Panos Datskos, Slo Rajic and Nickolay Lavrik ... today,s gyroscopes, which are big and costly. Instead, this ...
... with highly developed emotional sensibilities are better at making ... Journal of Consumer Research. "Consumers who understand their ... as health decisions and product choices," explain the authors, ... (University of Kentucky). "A person can know a lot ...
Cached Biology News:Story tips from the Department of Energy's Oak Ridge National Laboratory, June 2008 2Story tips from the Department of Energy's Oak Ridge National Laboratory, June 2008 3
(Date:1/22/2015)... Diego, California (PRWEB) January 22, 2015 ... Promotional Offer to their comprehensive portfolio of Eppendorf ... allows customers to purchase a Centrifuge 5424/5424 R and ... Bundle of either Eppendorf Research plus or Eppendorf Reference ...
(Date:1/22/2015)... Controlled Substance Compliance Services (CSCS), a project ... the legal requirements around using controlled substances in pharmaceutical ... As their international operations expand and become increasingly complex, ... as a result of the first phase of the ...
(Date:1/22/2015)... Nueva Jersey , 22 de enero de 2015  El ... abre hoy su llamada a nominaciones para 2015. Este ... ha hecho, o tiene el potencial para hacer, contribuciones ... nominaciones se aceptarán hasta el 15 de marzo de ...
(Date:1/22/2015)... , Jan. 22, 2015   GenoSpace , a precision ... tools to enable the broad use of genomic, imaging and ... the appointment of Michelle Munson , CEO of Aspera, ... Logo - http://photos.prnewswire.com/prnh/20150122/170713 ...
Breaking Biology Technology:Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Global Compliance Service for Controlled Substances to Expand to China 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4GenoSpace Expands Board with Appointment of Michelle Munson 2
... – makers of the ground-breaking hemostatic agent, WoundStat™ – today announced ... for its quality system for design, development, production and sales of ... August 2007 , ... BETHESDA, Md. (Business Wire ...
... this family reunion season, African Ancestry, Inc., offers 5 easy tips ... part of a growing trend that's changing the face of family ... ... 2008 -- By summer's end, thousands of Black families will have ...
... Therapy per Patient, Treated with an Antibiotic for MRSA Decreased ... New Data Released by ... Medical Resources,(AMR), a provider of premier market intelligence for the ... treated,with an antibiotic associated with a positive culture for MRSA ...
Cached Biology Technology: TraumaCure Receives Prestigious ISO 13485 Certification 2Families Embrace Science/Technology-based Ancestry Tracing Marking Milestone in Black Family Reunion Celebrations Across the Nation 2Families Embrace Science/Technology-based Ancestry Tracing Marking Milestone in Black Family Reunion Celebrations Across the Nation 3Number of Patients Treated with an Antibiotic for MRSA Within U.S. Acute Care Hospitals Increased 8 Percent from 2006 to 2007 2
... efficient delivery of siRNA while maintaining high ... to 96 samples simultaneously , ... harvest to post-electroporation incubation , ... Designed for use with the Bio-Rad ...
Agarose, pulse field, 250 g. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1800 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Mouse CXCR3 Allophycocyanin MAb (Clone 220803)...
Agarose, pulse field, 100 g. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1800 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Biology Products: