Navigation Links
Choline supplementation during pregnancy presents a new approach to schizophrenia prevention
Date:1/15/2013

AURORA, Colo. (Jan. 15, 2013) Choline, an essential nutrient similar to the B vitamin and found in foods such as liver, muscle meats, fish, nuts and eggs, when given as a dietary supplement in the last two trimesters of pregnancy and in early infancy, is showing a lower rate of physiological schizophrenic risk factors in infants 33 days old. The study breaks new ground both in its potentially therapeutic findings and in its strategy to target markers of schizophrenia long before the illness itself actually appears. Choline is also being studied for potential benefits in liver disease, including chronic hepatitis and cirrhosis, depression, memory loss, Alzheimer's disease and dementia, and certain types of seizures.

Robert Freedman, MD, professor and chairman of the Department of Psychiatry, University of Colorado School of Medicine and one of the study's authors and Editor of The American Journal of Psychiatry, points out, "Genes associated with schizophrenia are common, so prevention has to be applied to the entire population, and it has to be safe. Basic research indicates that choline supplementation during pregnancy facilitates cognitive functioning in offspring. Our finding that it ameliorates some of the pathophysiology associated with risk for schizophrenia now requires longer-term follow-up to assess whether it decreases risk for the later development of illness as well."

Normally, the brain responds fully to an initial clicking sound but inhibits its response to a second click that follows immediately. In schizophrenia patients, deficient inhibition is common and is related to poor sensory filtering and familial transmission of schizophrenia risk. Since schizophrenia does not usually appear until adolescence, this traitmeasurable in infancywas chosen to represent the illness.

Half the healthy pregnant women in this study took 3,600 milligrams of phosphatidylcholine each morning and 2,700 milligrams each eve
'/>"/>

Contact: Jackie Brinkman
jackie.brinkman@ucdenver.edu
303-724-1525
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related biology news :

1. A diet high in choline during pregnancy may mean less stress for baby
2. Vitamin D supplementation can decrease risk of respiratory infections in children
3. Study associates excess maternal iodine supplementation with congenital hypothyroidism in newborns
4. New study associates excess maternal iodine supplementation with congenital hypothyroidism
5. Prenatal micronutrient, food supplementation intervention in Bangladesh decreases child death rate
6. Chromosome anchors organize DNA during cell division
7. Music with dinner: Whales sing during foraging season, not just while breeding
8. Abuse during childhood linked to adult-onset asthma in African-American women
9. Insight into DNA reprogramming during egg and sperm cell development
10. OHSU study shows that a molecule critical to nerve cells increases drammatically during hypertension
11. New risk factor identified for high blood pressure during pregnancy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... MOUNTAIN VIEW, Calif. , Feb. 3, 2015 ... screen printer technology, demand from industries such as ... the global market for surface mount technology (SMT) ... manual equipment to automatic control will push the ... glue dispensers will remain steady as glue dispensers ...
(Date:1/22/2015)... Valid S.A. ("Company") (BM&FBOVESPA: VLID3 ON), is pleased to inform ... State of Washington,s Department of Licensing, in the ... issuance system for driver,s licenses and identification cards to its ... development will start in January 2015, with enrollment and card ...
(Date:1/22/2015)... 2015  Today, FreeWavz ( www.FreeWavz.com ), the developer ... on Fundable, https://www.fundable.com/freewavz . FreeWavz will be ... to meet customer demand. Logo - ... Invented by Dr. ...
Breaking Biology News(10 mins):End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3Valid USA Signs Contract For Washington Driver's License Issuance 2FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2
... to antibiotics acquire said resistance accidentally because they take ... to the stress to which they are subjected., A ... concerning an enigma that the scientific community has still ... the pharmaceutical industry: Why are bacteria becoming increasingly more ...
... and vitamin B12 to treatment with antipsychotic medication improved ... of more than 100 patients. The study focused on ... withdrawal, and a lack of emotional expressiveness. While the ... were more significant in individuals carrying specific variants in ...
... is complicated is an understatement, that it is little understood, ... the brain for three out of the five primary taste ... team of investigators from nine institutions discovered how ATP ... from sweet, bitter, and umami, or savory, taste bud cells. ...
Cached Biology News:New hypothesis: Why bacteria are becoming increasingly more resistant to antibiotics 2Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients 2Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients 3Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients 4How the body's energy molecule transmits 3 types of taste to the brain 2
(Date:2/26/2015)... 26, 2015  NuGene International, Inc. ("NuGene") (OTCQB: ... skin and hair rejuvenation, has announced that it ... record for investor relations and strategic communications. ... sales and diversification strategies – and we need ... shareholders," stated Ali Kharazmi CEO of NuGene when ...
(Date:2/26/2015)... (PRWEB) February 26, 2015 Already well ... gauging line by expanding its Length Gauge offerings with ... gauges. , Specifically, HEIDENHAIN’s pencil probe-style SPECTO ... force specification. Two new 1Vpp, 12mm stroke length ... force applications. One is a variant with a weak ...
(Date:2/26/2015)... Fla. , Feb. 26, 2015  Dyadic ... company whose patented and proprietary technologies are used ... proteins for the bioenergy, bio-based chemical, biopharmaceutical and ... report its financial results for year ending December ... 11, 2015 and will host a conference call ...
(Date:2/26/2015)... -- Epic Sciences announced today that President and CEO ... Annual Cowen and Company Health Care Conference on Wednesday, March ... Floor. The conference will be held at the Boston ... is developing diagnostic tests of high clinical utility to ... occur during the course of cancer treatments. From a ...
Breaking Biology Technology:NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 2NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 3Accuracy and Versatile Gauging Go Hand in Hand at HEIDENHAIN 2Dyadic International To Announce Fourth Quarter 2014 Financial Results And Host Conference Call On Wednesday, March 11, 2015 2Dyadic International To Announce Fourth Quarter 2014 Financial Results And Host Conference Call On Wednesday, March 11, 2015 3Epic Sciences to Present at 35th Annual Cowen and Company Health Care Conference 2
... ... Baltimore, MD, USA. This innovative annual event offers a prestigious roster of industry ... safety, scale-up, production, and emerging technologies. , ... Columbia, MD (PRWEB) October 11, 2009 -- METTLER TOLEDO announces ...
... a new "lab-on-a-chip" technique that analyses tiny samples of blood ... cancer much more quickly than ever before. "The concentration ... of metabolized estrogen in breast tissue are known to ... women, and is therefore believed to increase the risk of ...
... the State University of Pennsylvania (USA) and the Universidad ... replicate biological structures, such as butterfly wings, on a ... make optically active structures, such as optical diffusers for ... ability to change colours depending on the angle) or ...
Cached Biology Technology:17th International Process Development Conference to Feature Presentations on Safety, Process Development, Crystallization, PAT, Scale-Up and Production 2New lab-on-a-chip technique developed at U of T 2Nanometric butterfly wings created 2
...
... in two product models - the 5000AT+ and ... that the 6000AT+ includes a membrane desolvation unit ... improved detection limits and reduced oxides. The Ultrasonic ... elements by 10-40 times. Note that with ICP-MS ...
... is >95%\nNEN Radiolabeled Ligands\n\nReceptor-related research has long ... new radiolabeled ligands selected to keep pace ... range of products and services for receptor ... state-of-the-art radioligands. If you do not find ...
... was developed using a protein engineering approach that ... pocket of wild-type DNase I. These changes markedly ... The result is a versatile enzyme that has ... ability to maintain at least 50% of peak ...
Biology Products: