Navigation Links
Choline supplementation during pregnancy presents a new approach to schizophrenia prevention
Date:1/15/2013

AURORA, Colo. (Jan. 15, 2013) Choline, an essential nutrient similar to the B vitamin and found in foods such as liver, muscle meats, fish, nuts and eggs, when given as a dietary supplement in the last two trimesters of pregnancy and in early infancy, is showing a lower rate of physiological schizophrenic risk factors in infants 33 days old. The study breaks new ground both in its potentially therapeutic findings and in its strategy to target markers of schizophrenia long before the illness itself actually appears. Choline is also being studied for potential benefits in liver disease, including chronic hepatitis and cirrhosis, depression, memory loss, Alzheimer's disease and dementia, and certain types of seizures.

Robert Freedman, MD, professor and chairman of the Department of Psychiatry, University of Colorado School of Medicine and one of the study's authors and Editor of The American Journal of Psychiatry, points out, "Genes associated with schizophrenia are common, so prevention has to be applied to the entire population, and it has to be safe. Basic research indicates that choline supplementation during pregnancy facilitates cognitive functioning in offspring. Our finding that it ameliorates some of the pathophysiology associated with risk for schizophrenia now requires longer-term follow-up to assess whether it decreases risk for the later development of illness as well."

Normally, the brain responds fully to an initial clicking sound but inhibits its response to a second click that follows immediately. In schizophrenia patients, deficient inhibition is common and is related to poor sensory filtering and familial transmission of schizophrenia risk. Since schizophrenia does not usually appear until adolescence, this traitmeasurable in infancywas chosen to represent the illness.

Half the healthy pregnant women in this study took 3,600 milligrams of phosphatidylcholine each morning and 2,700 milligrams each eve
'/>"/>

Contact: Jackie Brinkman
jackie.brinkman@ucdenver.edu
303-724-1525
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related biology news :

1. A diet high in choline during pregnancy may mean less stress for baby
2. Vitamin D supplementation can decrease risk of respiratory infections in children
3. Study associates excess maternal iodine supplementation with congenital hypothyroidism in newborns
4. New study associates excess maternal iodine supplementation with congenital hypothyroidism
5. Prenatal micronutrient, food supplementation intervention in Bangladesh decreases child death rate
6. Chromosome anchors organize DNA during cell division
7. Music with dinner: Whales sing during foraging season, not just while breeding
8. Abuse during childhood linked to adult-onset asthma in African-American women
9. Insight into DNA reprogramming during egg and sperm cell development
10. OHSU study shows that a molecule critical to nerve cells increases drammatically during hypertension
11. New risk factor identified for high blood pressure during pregnancy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 2014  HITLAB SM announced today its ... to confirm its adherence to current U.S. Food ... HITLAB to conduct regulated smart device and smart ... patient safety and research quality. "HITLAB ... and delivery with innovative technology," said Laura ...
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the ... APAC Region 2015-2019"  report to their offering. ... market is advances in technology. With continuous advances ... solutions to the latest standard that meets the ...
(Date:12/10/2014)... -- Valencell, a leader in performance biometric data sensor technology, ... its licensees for highly accurate, clinically validated biometric technology. ... from fitness and health sectors, but first responders/military and ... only as useful as the biometric data it delivers. ... long-term mass consumer adoption of wearable products," said Dr. ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Wearable Technology Products Demand Highly Accurate Biometric Technology 2
... is available in Spanish . ,The ... caused serious damage to the ecosystems in the Bay of ... Country (UPV/EHU) has studied the consequences of this spill for ... The author of the PhD thesis is the biologist ...
... Australia,s most endangered snake might mean lighting more bush ... of broad-headed snakes are being threatened by encroaching woodland ... from the University of Sydney and Stanford University (USA) ... in small pockets within 200 km of Sydney, and ...
... / – To cope with the most disparaging economic ... the different varieties of standard-issue business strategies to steer ... following the "order of practice of the industry" would ... other radical cost-cutting measures. The consequence of overreacting to ...
Cached Biology News:The Prestige oil spill caused changes in the cell structure of mussels 2Australia's most endangered snake might need burning 2Recession Puts Focus on Business Optimisation and Excellence to Strengthen Business Core 2
(Date:12/19/2014)...  Decision Resources Group finds that the ... moderately through 2023 as the aging population, increasing adoption ... biomaterials all spur procedure volumes. Growth will be particularly ... and India , where ... for a larger proportion of the population. ...
(Date:12/19/2014)... --  ISN has released its third annual U.S. ... publication series. With data aggregated from over eight billion ... its online contractor management platform, ISNetworld, this three-part series ... statistics. The Contractor Performance ... available in two industry specific volumes: Oil & ...
(Date:12/17/2014)... 16, 2014 The Activated Carbon ... which is why IBISWorld updated its original industry research ... benefit from an intensified focus on environmental policy. Over ... emission standards for power plants and a range of ... IBISWorld Industry Analyst Sarah Kahn, “a range of downstream ...
(Date:12/17/2014)... December 16, 2014 “Never say, ... Philipps- Universität Marburg’s Department of Physics, advises young ... the newly released SPIE Women in Optics ... too shy to ask questions.” , In the ... and mathematics) occupations ranging from university professor and ...
Breaking Biology Technology:Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 2Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 3Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 3
... Study demonstrates ,Best buy in public health, LONDON, ... the ten years since its initiation, the international,effort to ... the world of one of its most debilitating diseases.,The ... 6.6 million,children from acquiring LF and stopped another 9.5 ...
... the U.S. Department of Energy (DOE) to commercialize cellulosic ethanol production ... ... 7, 2008-- POET, the largest producer of ethanol in the world, ... Department of Energy (DOE) to commercialize cellulosic ethanol production technology. A ...
... RVX, CALGARY, Oct. 7 /PRNewswire-FirstCall/ - Resverlogix ... in light of,the recent significant market drop of ... that the company fundamentals remain the same if,not ... business developments.,There is no reason for the price ...
Cached Biology Technology:LF Elimination Program Treats Over Half Billion People and Protects Millions More From Debilitating Disease 2LF Elimination Program Treats Over Half Billion People and Protects Millions More From Debilitating Disease 3LF Elimination Program Treats Over Half Billion People and Protects Millions More From Debilitating Disease 4POET Receives Additional $76 Million in Federal Funding For Commercialization of Cellulosic Ethanol 2