Navigation Links
Chloride increases response to pheromones and odors in mouse sensory neurons
Date:12/28/2009

The vomeronasal organ (VNO) is an odor detection system that mediates many pheromone-sensitive behaviors. Vomeronasal sensory neurons (VSNs), located in the VNO, are the initial site of interaction with odors and pheromones. How an individual VSN transduces chemical signals into electrical signals, however, has been a mystery. In the January 2010 issue of the Journal of General Physiology (www.jgp.org), researchers from the University of Vermont show that a Ca 2+ -activated chloride current contributes approximately 80% of the response to urine in mouse VSNs.

Using patch clamp recordings and whole cell recordings, the team found that that urine-induced inward current was decreased in the presence of chloride channel blockers. Furthermore, the urine-induced currents were eliminated when both extracellular Ca 2+ and Na + were removed. The team's overall findings show that chloride acts as a major amplifier for signal transduction in mouse VSNs, increasing the responsiveness to pheromones or odorants.


'/>"/>

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related biology news :

1. Chloride found at levels that can harm aquatic life in urban streams of the Northern US
2. Study finds Viagra increases release of key reproductive hormone
3. Springer increases publishing activities in South Korea
4. Age increases chance of success as two-timer
5. Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms
6. Waterborne carbon increases threat of environmental mercury
7. New study increases concerns about climate model reliability
8. Varying prevalence among ethnic groups of gene mutation that increases risk of breast cancer
9. Washington University increases fleet of Roche Genome Sequencer FLX Systems
10. Gene variant increases breast cancer risk
11. Ibuprofen or acetaminophen in long-term resistance training increases muscle mass/strength
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)...  Neurotechnology, a provider of high-precision biometric identification ... Identification System (ABIS) , a complete system for ... can process multiple complex biometric transactions with high ... face or iris biometrics. It leverages the core ... MegaMatcher Accelerator , which have been used in ...
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted to ... of 2015 The gross margin was 49% (27) ... operating margin was 40% (-13) Earnings per share rose ... was SEK 249.9 M (21.2) , Outlook   ... The operating margin for 2016 is estimated to exceed ...
(Date:4/26/2016)... 2016 Research and Markets has ... Market 2016-2020"  report to their offering.  , ,     ... The analysts forecast the global multimodal biometrics market ... the period 2016-2020.  Multimodal biometrics is ... as the healthcare, BFSI, transportation, automotive, and government ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... 24, 2016 , ... While the majority of commercial spectrophotometers and fluorometers use ... 6000i models are higher end machines that use the more unconventional z-dimension of 20mm. ... from the bottom of the cuvette holder. , FireflySci has developed several Agilent ...
(Date:6/23/2016)... June 23, 2016   Boston Biomedical , ... compounds designed to target cancer stemness pathways, announced ... granted Orphan Drug Designation from the U.S. Food ... gastric cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin ... to inhibit cancer stemness pathways by targeting STAT3, ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... and Mold) microbial test has received AOAC Research Institute approval 061601. , “This ... introduced last year,” stated Bob Salter, Vice President of Regulatory and Industrial Affairs. ...
(Date:6/23/2016)... ... 2016 , ... Supplyframe, the Industry Network for electronics hardware ... . Located in Pasadena, Calif., the Design Lab’s mission is to bring together ... built and brought to market. , The Design Lab is Supplyframe’s physical representation ...
Breaking Biology Technology: