Navigation Links
Case Western Reserve researchers develop 'wireless' activation of brain circuits
Date:2/23/2009

Traditionally, stimulating nerves or brain tissue involves cumbersome wiring and a sharp metal electrode. But a team of researchers at Case Western Reserve University is going "wireless."

And it's a unique collaboration between chemists and neuroscientists that led to the discovery of a remarkable new way to use light to activate brain circuits with nanoparticles.

Ben Strowbridge, an associate professor in the neurosciences department in the Case Western Reserve School of Medicine and Clemens Burda, an associate professor in chemistry, say it's rare in science that people from very different fields get together and do something that is both useful and that no one had thought of before. But that is exactly what they've done.

By using semiconductor nanoparticles as tiny solar cells, the scientists can excite neurons in single cells or groups of cells with infrared light. This eliminates the need for the complex wiring by embedding the light-activated nanoparticles directly into the tissue. This method allows for a more controlled reaction and closely replicates the sophisticated focal patterns created by natural stimuli.

The electrodes used in previous nerve stimulations don't accurately recreate spatial patterns created by the stimuli and also have potential damaging side effects.

"There are many different things you'd want to stimulate neurons for-injury, severed or damaged nerve to restore function- and right now you have to put a wire in there, and then connect that to some control system. It is both very invasive and a difficult thing to do," says Strowbridge.

IIn principle, the researchers should be able to implant these nanoparticles next to the nerve, eliminating the requirement for wired connections. They can then use light to activate the particles.

"We believe it has a lot of applicability," they said" Hopefully, the same thing can happen in the brain."

The researchers' p
'/>"/>

Contact: Jason A. Tirotta
jason.tirotta@case.edu
216-368-6890
Case Western Reserve University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Western diet linked to increased risk of colon cancer recurrence
2. UT Southwestern researchers identify hundreds of genes controlling female fertility
3. Northwestern to expose most deadly infectious diseases in 3-D
4. Northwestern study looks at sensing, movement and behavior
5. Tiny dust particles from Asian deserts common over western United States
6. Threatened bird species finds home at Western
7. BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
8. UT Southwestern secures $5 million NIH grant for lupus research
9. UT Southwestern scientist honored among best in Texas research
10. Western Groundfish Conference to be held in Santa Cruz on Feb. 4-8
11. Stem-cell transplantation improves muscles in MD animal model, UT Southwestern researchers report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... . , Animals ... such as exposure to predators. Researchers from the Max ... study on different populations of great tits that risk-taking ... High metabolic rates and low temperatures were associated with ... more likely to approach potential predators. , The readiness ...
(Date:9/30/2014)... who suffer from asthma may think there,s not a ... properly taking medications and avoiding allergic triggers. , ... of Allergy, Asthma and Immunology , the scientific publication ... (ACAAI), asthma sufferers can learn lessons about managing their ... the Annals article improved her asthma once she and ...
(Date:9/29/2014)... confirms that the exposure to tar tended to be ... cigarettes. Similarly, exposure to nicotine tended to be ... of cigarette in several countries around the world. Previous ... chemicals in the smoke of these cigarettes are lower ... of chemicals in the smoke are not necessarily linked ...
Breaking Biology News(10 mins):Risky metabolism 2Asthma symptoms kicking up? Check your exposure to air pollution 2Slim cigarette smokers not exposed to more harmful chemicals 2
... sinister about epilepsy: the disease affects the very core ... lead to seizures throughout the body or in parts of ... possible. The causes are still only partially understood but ... or metabolic diseases have been implicated. Epilepsy is not ...
... February 1, 2013 Poor impulse control contributes ... rewarding substances, like food, alcohol, and other drugs. ... FDA-approved medications for alcoholism, like naltrexone (Revia) and ... by curbing cravings and creating unpleasant reactions to ...
... levels of greenhouse gases, particularly carbon dioxide (CO2), ... fuels, deforestation, cultivation of grasslands, drainage of the ... shifts in climate patterns have led scientists to ... and to develop methods to evaluate how changes ...
Cached Biology News:Cats and humans suffer from similar forms of epilepsy 2If you are impulsive, take modafinil and count to 10 2New protocol recommendations for measuring soil organic carbon sequestration 2New protocol recommendations for measuring soil organic carbon sequestration 3New protocol recommendations for measuring soil organic carbon sequestration 4
(Date:9/30/2014)... (PRWEB) September 30, 2014 The custom ... ISPE Boston Product Show 2014. The Boston Area Chapter ... the 23rd annual, day-long event for Wed., Oct. 1 ... promises to be the largest in ISPE Boston’s long ... upward of 3,000 attendees expected. , HOLLOWAY AMERICA ...
(Date:9/30/2014)... 30, 2014 UFP Technologies, a ... packaging has recently introduced a custom insulated shipping ... . The new insulated shipper solves the issue ... process. UFP Technologies’ BioShell is a universal storage ... storage, handling and shipping. The insulated shipper keeps ...
(Date:9/29/2014)... Medical imaging is at the forefront of diagnostics ... imaging), CT (computerized tomography), scanning, and NMR (nuclear ... decades. However, persisting problems of image resolution and ... nature of living tissue. A solution is hyperpolarization, ... can increase imaging quality by following the distribution ...
(Date:9/29/2014)... diseases and biodiversity loss requires evolutionary thinking, argues ... Express that was co-authored by Bruce Tabashnik ... and Life Sciences. , For the first time, ... progress in addressing a broad set of challenges ... that consider evolutionary histories and the likelihood of ...
Breaking Biology Technology:HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 3UFP Technologies Introduces Insulated Shipping Container For Bulk Drug Transportation 2UFP Technologies Introduces Insulated Shipping Container For Bulk Drug Transportation 3A safer approach for diagnostic medical imaging 2A safer approach for diagnostic medical imaging 3Evolutionary biology: It's not just for textbooks anymore 2Evolutionary biology: It's not just for textbooks anymore 3
... May 4, 2011 Bacterin International Holdings, Inc. ("Bacterin") (NYSE ... graft material, today announced that its chairman and CEO, Guy ... Annual Equity Conference at the Hard Rock Hotel in Hollywood, ... At the time of the presentation, a live ...
... Neb., May 4, 2011 Transgenomic, Inc. (OTC/BB: ... Brugada Syndrome (BrS) test panel at the 2011 Heart Rhythm ... of 9 genes and broadens the test indication to include ... "The addition of two newly identified J-wave syndrome genes, ...
... May 4, 2011 NxStage Medical, Inc. (Nasdaq: ... products, today reported financial results for the first quarter ... above the top end of its guidance range. ... quarter of 2011 increased 25 percent to a record ...
Cached Biology Technology:Bacterin International to Present at Noble Financial Capital Markets' Seventh Annual Equity Conference on May 16, 2011 2Transgenomic, Inc. Enhances FAMILION® Genetic Test Offerings 2Transgenomic, Inc. Enhances FAMILION® Genetic Test Offerings 3Transgenomic, Inc. Enhances FAMILION® Genetic Test Offerings 4NxStage® Reports Record Revenue for the First Quarter of Fiscal 2011 2NxStage® Reports Record Revenue for the First Quarter of Fiscal 2011 3NxStage® Reports Record Revenue for the First Quarter of Fiscal 2011 4NxStage® Reports Record Revenue for the First Quarter of Fiscal 2011 5NxStage® Reports Record Revenue for the First Quarter of Fiscal 2011 6NxStage® Reports Record Revenue for the First Quarter of Fiscal 2011 7
Recorder REC-111 single-channel, 1. Category: Chromatography Systems & Accessories, Systems....
For the quantitative determination of cyclic AMP (cAMP) concentrations in cell culture supernates, serum, plasma, saliva, urine and cell lysates....
... Wide Range CRYETTE WR Cryoscope for molecular weight determinations for petroleum-based applications. Multiple solvents ... cyclohexanol, sulfolane. ... ... ...
... For the ultimate in utility and ... to meet the needs of the researcher. ... interior dimensions or as sheet material that ... enclosures. These isolators are autoclavable and non-cytotoxic ...
Biology Products: