Navigation Links
Carnegie Mellon researchers develop artificial cells to study molecular crowding and gene expression
Date:7/14/2013

t from a crowd of people, Tan said. If only a few people are in a room, it's easy for people to mingle, or even to become isolated. But in a crowded room where it's hard to move around, individuals will often tend to stay close to each other for extended periods. The same thing happens in a cell. If the intracellular space is crowded, binding between molecules increases.

Notably, the researchers found that the dense environments also made gene transcription less sensitive to environmental changes. When the researchers altered concentrations of magnesium, ammonium and spermidine chemicals that modulate the stability and binding of macromolecules they found higher perturbations of gene expression in low density environments than in high density environments.

"Artificial cellular systems have tremendous potential for applications in drug delivery, bioremediation and cellular computing," Tan said. "Our findings underscore how scientists could harness functioning mechanisms of natural cells to their advantage to control these synthetic cellular systems, as well as in hybrid systems that combine synthetic materials and natural cells."


'/>"/>

Contact: Byron Spice
bspice@cs.cmu.edu
412-268-9068
Carnegie Mellon University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Keck award enables Carnegie Mellon and Stanford to dramatically expand crowdsourced RNA design
2. Carnegies Greg Asner named Energy/Climate Fellow by US State Department
3. Carnegie Mellon fluorescent biosensor reveals mechanism critical to immune system amplification
4. Carnegies Wolf B. Frommer receives Bogorad Award for Excellence in Plant Biology
5. Carnegie Mellon Universitys Biometrics Center Selected To House New Pedo-Biometrics Research and Identity Automation Lab
6. Carnegie Mellon study shows skin-aging radicals age naturally formed particles in the air
7. Carnegies Donald Brown wins Lasker-Koshland Award
8. Carnegie Institution for Science receives Grand Challenges Explorations grant
9. Carnegie debuts revolutionary biosphere mapping capability at AGU
10. Carnegies Greg Asner elected to National Academy of Sciences
11. Carnegie Mellon neuroscientists discover new phase of synaptic development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... Environmental Protection Agency (EPA) today announced that environmental ... Massachusetts Amherst School of Public Health and Health ... to Achieve Results (STAR) grant to measure indoor ... hunters in subarctic North America to determine possible ... provide culturally-relevant recommendations for mitigation. , Peltier, who ...
(Date:7/23/2014)... by satellite over a 15-year period off the U.S. ... feed in specific locations each year, according to a ... PLOS ONE by Ladd Irvine from Oregon ... to mitigate human threats to the whale population. , ... recover since the establishment of protections in the mid-1960s. ...
(Date:7/23/2014)... Environment Canada has issued a high health risk warning ... in the region due to forest fires. In ... is drifting eastward along normal wind patterns. Fire ... comes from fires is not quite so obvious and ... any type of fire (forest, brush, crop, structure, tires, ...
Breaking Biology News(10 mins):Studying impacts of indoor air pollution on tribal communities 2Studying impacts of indoor air pollution on tribal communities 3Blue whales' dangerous feeding grounds 2
... MADISON, Wis. Transplantation of human stem cells in ... survival and muscle function in rats used to model ... muscles, causing death by respiratory failure. ALS (amyotrophic ... to the ALS Association, the condition strikes about 5,600 ...
... (May 27, 2013) A new study shows the ... significant spike in the number of young children treated ... "We have seen an increase in unintentional ingestions ... laws in Colorado," said George Wang, MD, lead author ...
... College researchers have identified a new regulator for plant hormone ... that may help to improve production of fruits, vegetables ... week of May 27 in the journal Proceedings of ... paper, titled "SCFKMD controls cytokinin signaling by regulating the degradation ...
Cached Biology News:Engineered stem cell advance points toward treatment for ALS 2Engineered stem cell advance points toward treatment for ALS 3Surge in children accidentally eating marijuana-laced foods 2Surge in children accidentally eating marijuana-laced foods 3KISS ME DEADLY proteins may help improve crop yields 2
(Date:7/23/2014)... , July 24, 2014 Lyfebulb, ... Pharmaceuticals Inc. (OTCQX and NASDAQ OMX First North ... or "the Company"), announced a collaboration to increase ... last night at an event attended by more ... parties. Lyfebulb is a health and wellness company ...
(Date:7/23/2014)... made great strides in saving China,s endangered national treasure, ... 65 giant panda reserves that have been established and ... 1596 pandas remain in the wild. , Breeding ... the panda by improving genetic diversity, avoid inbreeding and ... are these high-profile programs doing so far? , In ...
(Date:7/23/2014)... , July 23, 2014 /PRNewswire-iReach/ -- Think Drinks ... performance for the long term. They are the first ... of sustained energy as an alternative to the temporary ... Drinks on Indiegogo on July 29, 2014, with hopes ... campaign. Photo - http://photos.prnewswire.com/prnh/20140723/129697 ...
(Date:7/23/2014)... Last year, Formedix celebrated ... global provider of data management solutions for clinical trials. ... system for electronic data capture (EDC) and clinical data ... study execution tools added TrialMaster to its Transform for ... of Transform for TrialMaster, is being released this week, ...
Breaking Biology Technology:Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 2Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 3Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 4Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 5truBrain Neuroscientists To Launch More Effective, Healthier Alternative To Energy Drinks On Indiegogo 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3
... Inc., a privately held molecular diagnostics company developing innovative ... announced today the appointment of Peter Blume-Jensen, M.D., Ph.D. ... Metamark with over 20 years of experience in cancer ... Dr. Blume-Jensen was department head at EMD Serono, Inc. ...
... 16 Cord Blood America, Inc . ( ... the umbilical cord blood stem cell preservation company ... stem cells, a biological insurance policy, to families nationwide ... and CEO, was interviewed by analyst Francis Gaskins on ...
... LOUIS, Sept. 15 Sigma-Aldrich Corporation (Nasdaq: SIAL ... Healthcare Conference on Tuesday, September 21st at 12:30 PM ET ... audio broadcast over the Internet available at http://investor.sigmaaldrich.com/ . ... About Sigma-Aldrich: Sigma-Aldrich is ...
Cached Biology Technology:Metamark Genetics, Inc. Announces New Chief Scientific Officer 2Cord Blood America CEO Matthew Schissler Discusses Projects in China, South America, 'Afford-A-Cord,' and Profitability 2
Rabbit polyclonal to Vitronectin ( Abpromise for all tested applications). Antigen: Full length Vitronectin protein (Mouse). Entrez Gene ID: 7448 Swiss Protein ID: P04004...
... LNA technology enables sensitive and specific detection ... miRCURY LNA in situ detection probes have ... specific and sensitive detection of miRNAs. Specific ... in whole mounts, thin sections, single cells ...
... complete kit contains enough separation ... a total of 5 x ... includes the StemSep red magnet ... and buffers for the specific ...
... Product Mouse monoclonal [1320] to ... the p37 subunit of human Replication Factor C ... Cross-reacts with Human and S. cerevisiae. Not ... the p37 subunit of RFC1 Background ...
Biology Products: