Navigation Links
Cancer risk for African-American women with benign breast disease factors Wayne State finds
Date:2/11/2013

DETROIT A Wayne State University researcher has identified characteristics in benign breast disease associated with future cancer risk in African-American women.

Michele Cote, Ph.D., associate professor of oncology in the School of Medicine and the Barbara Ann Karmanos Cancer Institute, recently reviewed data from about 1,400 20- to 84-year-old African-American women who underwent breast biopsies between 1997 and 2000. Researchers identified biopsies that showed benign breast disease (BBD) and also tracked subsequent breast cancers.

BBD is an established risk factor for breast cancer among Caucasian women, Cote said, but less is known about it in African-American women, who tend to get breast cancer earlier, in more aggressive forms and die more frequently from it.

In "Benign Breast Disease and the Risk of Subsequent Breast Cancer in African American Women," published recently in the journal Cancer Prevention Research, she said 68 percent of women studied showed nonproliferative BBD, and 29 percent had the proliferative form of the disease without atypia, a state in which cells are not growing normally but are not cancerous.

The remaining 3 percent showed proliferative BBD with atypia, a percentage similar to a group of Caucasian women studied recently by the Mayo Clinic. Women in Cote's study with the proliferative form of the disease with atypia were three times as likely to develop breast cancer as women without proliferative disease.

A number of pathological characteristics are associated with BBD and breast cancer. Her group examined several of those, including the presence of cysts, fibrosis and atrophy of breast components, known clinically as lobular involution.

Another characteristic, columnar alteration, a variation in the way cells are structured, was shown to be associated with increased breast cancer risk. Cote said because columnar alterations are highly correlated with proliferative
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
2. Embryonic development protein active in cancer growth
3. BRG1 mutations confer resistance to hormones in lung cancer
4. Genetic variation in East Asians found to explain resistance to cancer drugs
5. Beyond the microscope: Identifying specific cancers using molecular analysis
6. Marshall University study may lead to new treatments for prostate cancer
7. Salk scientists open new window into how cancers override cellular growth controls
8. Penn research points to new way of preserving fertility for boys undergoing cancer treatment
9. Genetic abnormality offers diagnostic hope for childrens cancer
10. Protein jailbreak helps breast cancer cells live
11. Breast cancer risk gene discovery fast tracked by new technology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cancer risk for African-American women with benign breast disease factors Wayne State finds
(Date:6/23/2015)... BEACH GARDENS, Fla. , June 23, ... multi-factor identity management and authentication solutions, today announced ... Altus strong, multi-factor authentication solution.  The enhancements ... of use of the DigitalPersona Altus platform ... biometric reader compatibility. In today,s ...
(Date:6/17/2015)... Germany , June 17, 2015 ... Standard: QIA) today launched new Investigator ® STR assay ... the United States . The new genetic ... key genomic markers (short tandem repeats or STRs) for DNA ... evaluate the quality of DNA in each sample, a novel ...
(Date:6/16/2015)... 16, 2015  With the increasing number and severity ... top concern. The recent compromise of Federal employee ... strong authentication within government agencies. HYPR Corp. ... password (OTP) authenticator, has been submitted for testing and ... 3 validation for tamper proofing. The ...
Breaking Biology News(10 mins):Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 4QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 5Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 2Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 3
... genome consortium, consisted of scientists from China Agricultural University, ... the genome sequencing and analysis of the duck ( ... A viruses, which caused a new epidemic in China ... and provides an invaluable resource for unraveling the interactive ...
... Paris, France: French scientists have discovered that supposedly rare ... cells responsible for creating energy, account for more than ... as a respiratory deficiency. Their data emphasise ... DNA (mtDNA) in patients suspected as having a mitochondrial ...
... genetically modified (GM) cotton has significantly improved calorie consumption ... a 7-year-period, according to research published June 5 in ... Matin Qaim and Shahzad Kouser from the University of ... a survey of over 500 randomly selected small farm ...
Cached Biology News:The duck genome provides new insight into fighting bird flu 2Rare mitochondrial mutations -- maybe not so rare? 2
(Date:7/3/2015)... ... July 03, 2015 , ... The Alexander Group, a ... service industries alike-- typically known for its consummate professionalism-- embarks each year in ... and break from their day jobs. , "Our motto has always been work ...
(Date:7/3/2015)... July 3, 2015 ... september 2015 på  http://www.openinnovationinscience.at om efteruddannelsesprogrammet ... finder sted i Wien ... af internationale forskere og videnskabsmænd foretaget af ... største udfordringer for sundhedsvidenskaben manglen på incitamenter ...
(Date:7/2/2015)... ... July 02, 2015 , ... Sleepless nights will become obsolete as ... launched its Indiegogo campaign on June 23. Sound sleepers and the sleep deprived both ... effortless to use, while the integration of the Bluetooth speaker, alarm clock and ability ...
(Date:7/1/2015)... ... 2015 , ... The next-generation sequencing (NGS) clinical market is poised for huge ... industry. BCC Research reveals in its new report that the market drivers of this ... growing need for better diagnostics as part of a molecular diagnostics trend. , The ...
Breaking Biology Technology:The Alexander Group Declares Their Independence with a Bit of Levity 2Lancering af verdens første åbne innovationsprogram til uddannelse af forskere 2Lancering af verdens første åbne innovationsprogram til uddannelse af forskere 3Luzi Smart Lamp Recently Launched Indiegogo Campaign 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 3NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 3
... worldwide leader in e-document delivery ... and VSI-FAX(R) product families, announces ... This new solution allows Lotus ... efficiently, effectively, and economically with ...
... Company (environmental biotechnology) discusses no-net marketing, raising money, ... a time , ,Dan Williamson, president and ... has a powerful new proprietary technology that digests ... sewer collection system, In-Pipe continuously adds high quantities ...
... was goin down at the first-ever Wisconsin Entrepreneurs Conference in ... see people smiling about what they were doing and what ... roommates of mine hatched a plan to rid Lake Erie ... powers of multiplication were quickly making it the scourge of ...
Cached Biology Technology:Exclusive WTN Interview with Don Williamson 2Exclusive WTN Interview with Don Williamson 3Exclusive WTN Interview with Don Williamson 4Entrepreneurial Spirit Infectious in Milwaukee 2Entrepreneurial Spirit Infectious in Milwaukee 3
Reacti-Bind DNA Coating Solution...
... allows real-time observations of cell cultures under ... 64 different strain parameters in addition to ... silicon strain chamber used by the ST-195 ... microscopy. ST-195 can be used with Nikon, ...
... regulate cell stretching or compression of a ... Computer controlled so you can precisely regulate ... to produce 64 unique strain parameters. ST-160 ... ST-150. Both models are compatible with Nikon, ...
... The RC DC protein assay reagents package ... presence of reducing agents and detergents. The RC ... package includes reagents sufficient for 500 standard assays: ... reagent II, 250 ml alkaline copper tartrate solution, ...
Biology Products: