Navigation Links
Cancer risk for African-American women with benign breast disease factors Wayne State finds
Date:2/11/2013

DETROIT A Wayne State University researcher has identified characteristics in benign breast disease associated with future cancer risk in African-American women.

Michele Cote, Ph.D., associate professor of oncology in the School of Medicine and the Barbara Ann Karmanos Cancer Institute, recently reviewed data from about 1,400 20- to 84-year-old African-American women who underwent breast biopsies between 1997 and 2000. Researchers identified biopsies that showed benign breast disease (BBD) and also tracked subsequent breast cancers.

BBD is an established risk factor for breast cancer among Caucasian women, Cote said, but less is known about it in African-American women, who tend to get breast cancer earlier, in more aggressive forms and die more frequently from it.

In "Benign Breast Disease and the Risk of Subsequent Breast Cancer in African American Women," published recently in the journal Cancer Prevention Research, she said 68 percent of women studied showed nonproliferative BBD, and 29 percent had the proliferative form of the disease without atypia, a state in which cells are not growing normally but are not cancerous.

The remaining 3 percent showed proliferative BBD with atypia, a percentage similar to a group of Caucasian women studied recently by the Mayo Clinic. Women in Cote's study with the proliferative form of the disease with atypia were three times as likely to develop breast cancer as women without proliferative disease.

A number of pathological characteristics are associated with BBD and breast cancer. Her group examined several of those, including the presence of cysts, fibrosis and atrophy of breast components, known clinically as lobular involution.

Another characteristic, columnar alteration, a variation in the way cells are structured, was shown to be associated with increased breast cancer risk. Cote said because columnar alterations are highly correlated with proliferative
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
2. Embryonic development protein active in cancer growth
3. BRG1 mutations confer resistance to hormones in lung cancer
4. Genetic variation in East Asians found to explain resistance to cancer drugs
5. Beyond the microscope: Identifying specific cancers using molecular analysis
6. Marshall University study may lead to new treatments for prostate cancer
7. Salk scientists open new window into how cancers override cellular growth controls
8. Penn research points to new way of preserving fertility for boys undergoing cancer treatment
9. Genetic abnormality offers diagnostic hope for childrens cancer
10. Protein jailbreak helps breast cancer cells live
11. Breast cancer risk gene discovery fast tracked by new technology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cancer risk for African-American women with benign breast disease factors Wayne State finds
(Date:7/25/2014)... MOResearchers at the Stowers Institute for Medical Research ... pheromone receptors, and found pheromones crucial to triggering the ... of receptors helps a male mouse detect pheromones that ... of receptors lets him know if the female mouse ... pheromones are critical to trigger mating. Stowers, researchers believe ...
(Date:7/24/2014)... 2014) Scientists at The New York Stem ... closer to creating a viable cell replacement therapy ... , For the first time, NYSCF scientists ... skin samples of patients with primary progressive multiple ... to induce these stem cells into becoming oligodendrocytes, ...
(Date:7/24/2014)... 24, 2014) Scientists at The New York ... step closer to creating a viable cell replacement ... cells. , For the first time, NYSCF ... from skin samples of patients with primary progressive ... protocol to induce these stem cells into becoming ...
Breaking Biology News(10 mins):It takes two to court 2It takes two to court 3NYSCF scientists one step closer to cell therapy for multiple sclerosis patients 2NYSCF scientists 1 step closer to cell therapy for multiple sclerosis patients 2
... As the human population increases, so too do the ... issue of International Journal of Plant Sciences , ... Sarah Assmann explores how the responses to environmental stresses ... possible approaches to addressing growing human demand for crop ...
... despite the yuck factor, have captured the hearts of two ... team that this week is publishing the leech,s complete genome ... Weisblat, a UC Berkeley professor of molecular and cell biology ... sequencing initiative that has targeted a variety of animals in ...
... the quest to find the easiest and fastest way to ... In an article published in Frontiers in Microbiology on ... polymerase chain reaction (PCR) system to discover specific gene targets ... show that assays performed using this PCR system are rapid, ...
Cached Biology News:Can observations of a hardy weed help feed the world? 2What do leeches, limpets and worms have in common? Now, a sequenced genome 2What do leeches, limpets and worms have in common? Now, a sequenced genome 3USDA explores using novel genetic labs for faster detection of E. coli 2
(Date:7/24/2014)... A novel combination of microscopy and data processing has ... National Laboratory an unprecedented look at the surface of ... properties. , The research team led by ORNL,s ... a perovskite manganite, a complex material that exhibits dramatic ... surface behavior could benefit researchers who are interested in ...
(Date:7/24/2014)... worldwide rely on sophisticated equipment, trained personnel, and ... areas against terrorist attacks. A revolutionary new electronic ... make their job much easier. , The groundbreaking ... Tel Aviv University ,s School of Chemistry and ... the Herzliya company Tracense, picks up the scent ...
(Date:7/24/2014)... , July 24, 2014 Research ... "Global Cell Culture Market 2014-2018" report to ... Cell culture is the in vitro growth ... as research, cell studies, and biopharmaceutical production. Cell culture ... production. Cell culture instruments and cell culture consumables are ...
(Date:7/24/2014)... Francisco, CA (PRWEB) July 24, 2014 ... to be semi-finalists in Livestrong’s Big C Competition. Out ... Health are each headed to the semi-final round. In ... Livestrong’s exclusive three-month accelerator program, complete with mentoring from ... , As part of the angelMD commitment to ...
Breaking Biology Technology:ORNL study reveals new characteristics of complex oxide surfaces 2Nano-sized chip 'sniffs out' explosives far better than trained dogs 2Global Cell Culture Market 2014-2018: Key Vendors are Becton, Dickinson and Co, EMD, GE Healthcare, Lonza Group, Sigma Aldrich and Thermo Fisher Scientific 23 angelMD Startups Make Livestrong Big C Semi-finals 2
... October 1 , - "Expert Consult" ... Content is Always Current, Elsevier, the ... the publication of the 40th edition of ... Gray,s Anatomy: The Anatomical Basis of Clinical,Practice ...
... product design and development, manufacture, and distribution ... ... 1 Cylex has announced receipt of,certification to ISO ... Canadian Medical Devices Conformity Assessment,System (CMDCAS). These certifications signify ...
... Sept. 30 NxStage Medical,Inc. (Nasdaq: NXTM ), ... Jeffrey H. Burbank, Chief Executive Officer,and Robert S. Brown, ... Healthcare Focus Conference on October 6, 2008 at Le ... is scheduled for Monday, October 6th at,2:30 p.m. ET. ...
Cached Biology Technology:New 40th Edition of Gray's Anatomy Celebrates 150 Years as the World's Preeminent Anatomical Reference 2New 40th Edition of Gray's Anatomy Celebrates 150 Years as the World's Preeminent Anatomical Reference 3Cylex(TM) Receives ISO 13485:2003 and 9001:2000 Quality Certifications 2NxStage Medical to Present at JMP Securities Healthcare Focus Conference 2
Request Info...
...
Agarose-LE, 250 g. Suitable for soft agarose cloning. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1200 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Request Info...
Biology Products: