Navigation Links
Cancer is a result of a default cellular 'safe mode,' physicist proposes
Date:6/30/2013

With death rates from cancer have remained largely unchanged over the past 60 years, a physicist is trying to shed more light on the disease with a very different theory of its origin that traces cancer back to the dawn of multicellularity more than a billion years ago.

In this month's special issue of Physics World devoted to the "physics of cancer", Paul Davies, principal investigator at Arizona State University's Center for Convergence of Physical Sciences and Cancer Biology, explains his radical new theory.

Davies was brought in to lead the centre in 2009 having almost no experience in cancer research whatsoever. With a background in theoretical physics and cosmology, he was employed to bring fresh, unbiased eyes to the underlying principles of the disease.

He has since raised questions that are rarely asked by oncologists: thinking about why cancer exists at all and what place it holds in the grand story of life on Earth.

His new theory, drawn together with Charles Lineweaver of the Australian National University, suggests that cancer is a throwback to an ancient genetic "sub-routine" where the mechanisms that usually instruct cells when to multiply and die malfunctions, thus forcing the cells to revert back to a default option that was programmed into their ancestors long ago.

"To use a computer analogy, cancer is like Windows defaulting to 'safe mode' after suffering an insult of some sort," Davies writes.

The result of this malfunction is the start of a cascade of events that we identify as cancer a runaway proliferation of cells that form a tumour, which eventually becomes mobile itself, spreading to other parts of the body and invading and colonizing.

Orthodox explanations suppose that cancer results from an accumulation of random genetic mutations, with the cancer starting from scratch each time it manifests; however, Davies and Lineweaver believe it is caused by a set of genes
'/>"/>

Contact: Joseph Winters
joseph.winters@iop.org
020-747-04815
Institute of Physics
Source:Eurekalert

Page: 1 2

Related biology news :

1. Continued research needed on treatment for women with lung cancer who are never smokers
2. TGen and Ventana Medical Systems Inc. join forces to fight cancer
3. National Institutes of Health to fund research probing proteins linked to cancer, diabetes
4. Herding cancer cells to their death
5. No danger of cancer through gene therapy virus
6. An article in Cell reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer
7. Osteoporosis drug stops growth of breast cancer cells, even in resistant tumors
8. Using math to kill cancer cells
9. Gene variants may predict who will benefit from breast cancer prevention drugs
10. Nanotechnology helps track and improve drug action in pancreatic cancer
11. Biomarker identification may lead to new noninvasive test for colorectal cancer detection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... May 5, 2015, NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market, reminds investors and media ... Officer, is presenting  at CARTES SECURE CONNEXIONS AMERICA 2015, held ... The three-day conference is organized into a ... in is themed Global Fraud: Where is the Trust ...
(Date:4/27/2015)... Apr. 27, 2015 Profile Solutions, Inc. (OTC: ... security systems is pleased to announce that Dr ... consultant and member of its scientific advisory board. ... as a thought leader in technology-enhanced learning models. He ... and has published studies and books focused on online ...
(Date:4/20/2015)... The announcement comes as demand for fire vault ... Ireland,s foremost records management company, has secured ... impressive track record of clients within the first 12 months, ... sector in Dubai . As a result, ... a further eight staff members at its Irish headquarters. The ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3
... lasers. We use them to print out documents, play CDs ... monitor our bloodstream, and even remove tumors from our bodies. ... Physics IAF in Freiburg have developed the technology for a ... of infrared laser forms the core of an analysis ...
... the sacred beetles of ancient Egypt the scarab beetle group ... of the most vulnerable representatives are contained in the flightless ... A recent study published in the open access journal ... distribution from southern Africa. The two new species ...
... has renewed its prestigious Clinical and Translational Science ... (STSI) in the amount of $29 million over ... in genomics, wireless technology and bioinformatics toward individualizing ... between Scripps Health and The Scripps Research Institute ...
Cached Biology News:Lasers offer an automated way to test drinking water 2Lasers offer an automated way to test drinking water 3NIH awards Scripps Translational Science Institute $29 million grant 2NIH awards Scripps Translational Science Institute $29 million grant 3
(Date:5/26/2015)... California and HILDEN, Germany ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt ... of its QIAGEN Clinical Insight ® (QCI™) ... labs to interpret and report on genomic variants ... supported applications for the bioinformatics platform are in ...
(Date:5/26/2015)... 2015 Global Stem Cells Group ... for the company’s first cellular and regenerative medicine symposium ... full day, hands-on stem cell training class Oct. 10. ... Gimenez, M.D., President of Therapeutic Confrontations (CONFTERA) in Barcelona. ... interest in regenerative medicine and recent advances in cellular ...
(Date:5/26/2015)... 2015 Leading Regenerative Veterinary Medicine® ... long-term relationship with Veterinary Growth Partners, a membership ... to provide access to vital services to veterinary ... VGP as a dedicated partner in bringing stem ... Concentrating and using stem cells natural abilities to ...
(Date:5/26/2015)... 2015 /PRNewswire/ - Fluorinov Pharma (Fluorinov), a FACIT portfolio ... Beshar to its Board of Directors.  His appointment ... expertise as Fluorinov accelerates its clinical development activities.  ... is a pleasure to welcome Luke to the Board ... the strategy, financial strength and success of multiple organizations," ...
Breaking Biology Technology:QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 2QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 3QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 4QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 5Stem Cell Training, Inc. Announces First European Symposium on Cellular and Regenerative Medicine 2Stem Cell Training, Inc. Announces First European Symposium on Cellular and Regenerative Medicine 3VetStem Biopharma & Veterinary Growth Partners Join Forces to Increase Member Veterinary Hospital Revenue Through Cutting Edge Medical Offering 2VetStem Biopharma & Veterinary Growth Partners Join Forces to Increase Member Veterinary Hospital Revenue Through Cutting Edge Medical Offering 3Luke M. Beshar Appointed to Fluorinov Pharma Board of Directors 2Luke M. Beshar Appointed to Fluorinov Pharma Board of Directors 3
... 3 Cardiac Science,(Nasdaq: CSCX ) ... rehabilitation, and informatics products, announced the,appointment today ... President and Chief,Operating Officer., (Logo: ... position to build our strategic capabilities at ...
... drug discovery research and high throughput screening applications, global market for ... by 2015. A key driving force is the increasing involvement of ... ... San Jose, CA (PRWEB) November 3, 2008 -- Playing ...
... researchers have synthesized an elusive metal-hydroxide compound in ... way for improved precursor inks that could boost ... to a "bottom-up" production of possibly the first ... nitroso-butylamine as an additive in place of nitrosobenzene. ...
Cached Biology Technology:Cardiac Science Appoints Dave Marver as Chief Operating Officer 2Cardiac Science Appoints Dave Marver as Chief Operating Officer 3Microplate Instrumentation & Supplies Market to Exceed $5.0 Billion by 2015, According to New Report by Global Industry Analysts, Inc 2Microplate Instrumentation & Supplies Market to Exceed $5.0 Billion by 2015, According to New Report by Global Industry Analysts, Inc 3New nanocluster to boost thin films for semiconductors 2
recombination at attR1 and attR2 sites...
... Streptavidin-Horseradish Peroxidase Conjugate, 2 ... reporter enzyme molecules for ... in situ hybridization applications.High ... & Labeling & Detection, ...
Whole rabbit blood (any breed, either sex) is collected at the time of slaughter and processed immediately at 4C, bottled, frozen and stored at -70C....
Chicken anti-EEA1...
Biology Products: