Navigation Links
Caltech scientists control complex nucleation processes using DNA origami seeds
Date:4/8/2009

t themselves," says Winfree.

But, he adds, while bottom-up approaches have been extremely useful in biology, they haven't played as significant a role in technology, "because we don't have a great grasp on how to design systems that build themselves. Most examples of bottom-up technologies are specific chemical processes that work great for a particular task, but don't easily generalize for constructing more complex structures."

To understand how complexity can be programmed into bottom-up molecular fabrication processes, Winfree and his colleagues study and understand the processes--or algorithms--that generate organization not just in computers but also in the natural world.

"Tasks can be solved by carrying out well-defined rules, and these rules can be carried out by a mindless mechanism such as a computer," he says. "The same set of rules can perform different tasks when given different inputs, and there exist 'universal programs' that can perform any task required of it, as specified in its input. Your laptop is such a universal computer; it can run any software that you download, and in principle, any feasible task could be programmed."

These principles also have been exploited by natural evolution, Winfree says: "Every cell, it appears, is a kind of universal computer that can be instructed in seemingly limitless ways by a DNA genome that specifies what chemical processes to execute, thus building an active organism. The aim of my lab has been to understand algorithms and information within molecular systems."

Winfree's investigations into algorithmic self-assembly earned him a MacArthur "genius" prize in 2000; his collaborator, Paul W. K. Rothemund, a senior research associate at Caltech and a coauthor of the PNAS paper, was awarded the same no-strings-attached grant in 2007 for his work designing scaffolded "DNA origami" structures that self-assemble into nearly arbitrary shapes (such as a smiley face and
'/>"/>

Contact: Kathy Svitil
ksvitil@caltech.edu
626-395-8022
California Institute of Technology
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. UNC, Caltech research finds further evidence for genetic contribution to autism
2. Caltech researchers find dual-use sexual attraction and population-control chemicals in nematodes
3. Caltech scientists awarded $20 million to Power the Planet
4. Caltech neurobiologists discover individuals who hear movement
5. Caltech engineers build mini drug-producing biofactories in yeast
6. Caltech researchers awarded $10M for molecular programming project
7. Caltech scientists create DNA tubes with programmable sizes for nanoscale manufacturing
8. Caltech biologists spy on the secret inner life of a cell
9. Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system
10. Caltech engineers build firast-ever multi-input plug-and-play synthetic RNA device
11. Caltech geobiologists discover unique magnetic death star fossil
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Caltech scientists control complex nucleation processes using DNA origami seeds
(Date:8/4/2015)... Research and ... addition of the "Digital Forensics Market ... (Computer Forensics, Network Forensics, Mobile Device Forensics, ... and Region - Global Forecast to 2020" ... By Component (Hardware, Software, and Service), Sub-Segment ...
(Date:8/3/2015)... Calif. , Aug. 3, 2015 Synaptics, ... human interface solutions, today announced that members of the ... at the Pacific Crest Global Technology Leadership Forum on ... The conference will be held at the Sonnenalp Resort ... The presentation may include forward-looking information. An audio ...
(Date:7/31/2015)... , 31 de julio de 2015 ... (ICG-10,  www.icg-10.org ) del 22 al 25 de octubre ... La conferencia celebra su décimo aniversario este ... convertido en una de las reuniones anuales más influyentes ... es una de las conferencias científicas más dinámicas, entusiastas ...
Breaking Biology News(10 mins):Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3
... sensitive to radiation, which poses an impossible dilemma for ... cancer. Now researchers from Rensselaer Polytechnic Institute have developed ... safer, more accurate, and more effective radiation therapy and ... is a doubled-edged sword: It holds the power to ...
... Wash. Richard D. Smith, Battelle Fellow at the U.S. ... one of 50 outstanding leaders in the 2007 Scientific American ... 50 key contributors in science and technology. Smith shared ... with a colleague from UCLAs David Geffen School of Medicine, ...
... the aorta and promotes coronary atherosclerosis, more commonly known ... by Yale School of Medicine in Cell Metabolism. ... Akt1 gene and fed a high cholesterol diet had ... littermates. And, surprisingly, their coronary lesions were similar to ...
Cached Biology News:Safer, more accurate radiation therapy for expecting mothers 2Safer, more accurate radiation therapy for expecting mothers 3PNNL's Richard Smith named to prestigious Scientific American 50 list of outstanding leaders 2
(Date:9/2/2015)... , Sep. 02, 2015 ... announced the addition of Jain PharmaBiotech,s new report ... to their offering. This report follows ... characteristic that can be objectively measured and evaluated ... processes as well as pharmacological responses to a ...
(Date:9/2/2015)... , Sept. 2, 2015  Neurotech Pharmaceuticals, Inc., ... in the multicenter Phase 2 clinical trial of ... treatment of recurrent subfoveal choroidal neovascularization secondary to ... a unique vascular endothelial growth factor (VEGF) receptor ... "This landmark proof-of-concept study will evaluate ...
(Date:9/2/2015)... , September 2, 2015 BiondVax ... of the National Institute of Allergy and Infectious Diseases (NIAID), ... the Department of Health and Human Services (HHS), to launch ... the United States in the 2015-16 timeframe. ... vaccine candidate, Multimeric-001 (M-001), as a primer vaccine, which would ...
(Date:9/2/2015)... ... September 02, 2015 , ... The ... creating professional commercial video content, to analysis of athletic performance. Producing high-resolution ... go by too quickly to process with the naked eye. , Slow ...
Breaking Biology Technology:Updated 2015 Biomarkers Report - Latest Technologies, Markets and Companies Insights to 2024 with over 1,000 References 2Updated 2015 Biomarkers Report - Latest Technologies, Markets and Companies Insights to 2024 with over 1,000 References 3Neurotech Announces First Patient Enrolled in Novel Anti-VEGF Encapsulated Cell Therapy Study 2Neurotech Announces First Patient Enrolled in Novel Anti-VEGF Encapsulated Cell Therapy Study 3Neurotech Announces First Patient Enrolled in Novel Anti-VEGF Encapsulated Cell Therapy Study 4BiondVax Announces Intent to Launch a Phase 2 Trial in the United States in Collaboration with the U.S. National Institutes of Health 2BiondVax Announces Intent to Launch a Phase 2 Trial in the United States in Collaboration with the U.S. National Institutes of Health 3Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 2Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 3
... embryonic-like human proteins stimulate skin cells to combat aging and help ... ... 27, 2009 -- Histogen Aesthetics , a division of Histogen ... aesthetics medicine, today announced the launch of the ReGenica™ Rejuvenation System ...
... LaVoie Group, a life science-focused strategic communications agency, announced ... agency of record for Pegasus Biologics, Inc. Donna L. ... has the opportunity to capture the significant market share ... the standard of care in three initial markets: limb ...
... 7th, 2008, a year before the recent Mexico and ... state the likelihood of H1N1 outbreaks based on its ... in virus genes which have been linked with past ... the Web, stated that in H1N1 the company had ...
Cached Biology Technology:Histogen Aesthetics Launches ReGenica Rejuvenation System 2Histogen Aesthetics Launches ReGenica Rejuvenation System 3Histogen Aesthetics Launches ReGenica Rejuvenation System 4LaVoie Group Adds Bio-Surgery Company, Pegasus Biologics, to Its Life Sciences Agency Roster 2Biotechnology Company Provided Advance Warning of Mexican H1N1 "Swine Flu" Virus Outbreak 2Biotechnology Company Provided Advance Warning of Mexican H1N1 "Swine Flu" Virus Outbreak 3Biotechnology Company Provided Advance Warning of Mexican H1N1 "Swine Flu" Virus Outbreak 4
... a fully automated microplate based multi-detection ... in academia and industry. The FLUOstar ... Fluorescence Intensity including FRET and ... including DELFIATM High-Performance Luminescence (flash ...
... can operate as a Voltage Clamp, as a ... in electrophysiology research applications. Performance in any one ... • This amazing instrument ... the capabilities of Digital Signal Processing (DSP) integrated ...
... activity is expressed in g per ml and ... saline, pH 6.8, of a 1 mg per ... lowest concentration to agglutinate a 2% suspension of ... incubation at 25 C. Preparation Note: ...
... save space and organize gloves, ... other garb. They are the ... small parts used in labs, ... Open-slot design for easy cleaning. ...
Biology Products: