Navigation Links
Caltech researchers train computers to analyze fruit-fly behavior
Date:4/8/2009

PASADENA, Calif.--Scientists at the California Institute of Technology (Caltech) have trained computers to automatically analyze aggression and courtship in fruit flies, opening the way for researchers to perform large-scale, high-throughput screens for genes that control these innate behaviors. The program allows computers to examine half an hour of video footage of pairs of interacting flies in what is almost real time; characterizing the behavior of a new line of flies "by hand" might take a biologist more than 100 hours.

This work--led by Pietro Perona, the Allen E. Puckett Professor of Electrical Engineering at Caltech, and David J. Anderson, the Roger W. Sperry Professor of Biology at Caltech, and a Howard Hughes Medical Institute Investigator--is detailed in the April issue of Nature Methods.

"Everyone wants to know how genes control behavior," notes Anderson. "But in order to apply powerful genetic analyses to complicated social behaviors like aggression and courtship, you need accurate ways of measuring--of scoring--those behaviors."

Previously, the only way to do this was to have students "watch video tapes over and over to record one particular type of behavior at a time," says Anderson. Using this method to measure a number of different types of behaviors--like lunging, tussling, chasing, circling, and copulating--or even to determine the way the flies orient their bodies or set their wings when they encounter another fly, requires the student to watch the same bit of video repeatedly, each time looking at the behavior of a single pair of flies. "In order to screen for mutations affecting aggressive behavior, we would have to analyze something like 2,000 pairs of flies," says Anderson. "It's been virtually impossible to do this without a small army of graduate students."

Enter Perona and Heiko Dankert, a postdoctoral scholar in electrical engineering. Using the techniques of machine vision and combining the
'/>"/>

Contact: Lori Oliwenstein
lorio@caltech.edu
626-395-3631
California Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Caltech and UCSD researchers shed light on how proteins find their shapes
2. Caltech researchers help unlock the secrets of gene regulatory networks
3. Caltech researchers get first look at how groups of cells coordinate their movements
4. Caltech scientists show function of helical band in heart
5. Caltech scientists develop barcode chip for cheap, fast blood tests
6. Celebrated UH researcher invited to Caltech as distinguished scholar
7. Caltech researchers get first 3-D glimpse of bacterial cell-wall architecture
8. Caltech-led researchers find negative cues from appearance alone matter for real elections
9. Caltech geobiologists discover unique magnetic death star fossil
10. Caltech engineers build firast-ever multi-input plug-and-play synthetic RNA device
11. Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/19/2015)... Feb .19, 2015 Research and Markets ... of the "Military Electro-Optical / Infrared Systems ... by Platform - Forecast to 2020" report ... electro-optical/infrared systems market is expected to reach $16.35 ... 7.71%. This report segments the military ...
(Date:2/13/2015)... Feb. 13, 2015 ACT Genomics Co., ... aims to transform cancer genomic information into precision ... company has raised US$ 8 million in the its ... Taipei, Taiwan , ACT Genomics ... With the aim to implement next generation sequencing ...
(Date:2/12/2015)... , Feb. 12, 2015 NXT-ID, Inc. ... the "Company"), a biometric authentication company focused on the ... filed provisional patent 62/113114 for DISTRIBUTED METHOD ... The patent further establishes NXT-ID,s position in ... intellectual property portfolio the ability for multiple devices to ...
Breaking Biology News(10 mins):Military Electro-Optical / Infrared Systems (Image Intensification, Laser, Infrared) Market - Forecast to 2020: Featuring Profiles of the Market Leaders on this $16 Billion market 2Military Electro-Optical / Infrared Systems (Image Intensification, Laser, Infrared) Market - Forecast to 2020: Featuring Profiles of the Market Leaders on this $16 Billion market 3ACT Genomics Raises $8 Million in its First Private Funding Round 2NXT-ID Patents Collaborative Services to Enable the "Internet of Things" 2NXT-ID Patents Collaborative Services to Enable the "Internet of Things" 3
... do a herd of gazelles and a fluffy mass ... describes the population dynamics of such prey animals as ... the relationship between cloud systems, rain and tiny floating ... understand, among other things, how human-produced aerosols affect rainfall ...
... several outbreaks of West Nile Virus, which causes fever or ... by blood-sucking mosquitoes, have been seen in the U.S., usually ... virus migrated here and they don,t know how, or ... of Tel Aviv University,s School of Public Health at the ...
... Northwest Forest Plan enacted in 1993 was designed to conserve ... owl, but researchers conclude in a new study that it ... on public lands. When forest harvest levels fell 82 ... of this act, they became a significant carbon "sink" for ...
Cached Biology News:Eat, prey, rain 2Catching the West Nile virus in action 2Northwest Forest Plan has unintended benefit - carbon sequestration 2
(Date:3/2/2015)... In the five years to 2015, the ... growth. The industry, which consists of companies that perform ... other goods, has grown on account of an improving ... IBISWorld forecasts that industry revenue will increase at an ... the five-year period, including an anticipated increase of 2.8% ...
(Date:3/2/2015)... GAITHERSBURG, Md. , March 2, 2015 /PRNewswire/ ... Gaithersburg -based biotechnology company focusing on the ... and next generation antibody agents based upon a ... received a 2015 Life Sciences Impact Grant Award ... (MCDED).  The grant, created by MCDED, is awarded ...
(Date:3/2/2015)... , March 2, 2015 ... healthy whole food nutrition products reveal technological advancements ... related disorders such as hyperglycemia, obesity, insulin level ... Nutraceutical and Biotech Companies in focus today are: RiceBran ... Foods Ltd. (NYSE: ANFI ), CEL-SCI ...
(Date:3/2/2015)... Calif. , March 2, 2015 ... company developing therapies for autoimmune and infectious diseases, ... (USPTO) has issued an important new composition of ... function through the targeting of CLIP. ... peptide technology underlying VG Life Sciences, VG1177, a ...
Breaking Biology Technology:Laboratory Testing Services in Canada Industry Market Research Report Now Available from IBISWorld 2Laboratory Testing Services in Canada Industry Market Research Report Now Available from IBISWorld 3VLP Therapeutics Wins the 2015 Life Sciences Impact Grant Award from the Montgomery County Department of Economic Development 2Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 2Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 3Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 4Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 5Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 6Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 7VG Life Sciences Granted Key Composition Of Matter Patent 2VG Life Sciences Granted Key Composition Of Matter Patent 3
... know there are at least five different types of patent ... (1) a search for competitors patents, (2) a clearance search, ... a patent validity search. Each type of search has a ... for competitors patents ,A search for competitors patents is ...
... business. , ,I call it the "humanizing factor" at work. A ... corporate world and the behavior of people in it, but in ... regular people at work (sometimes when you least expect it). , ... examples of the HF in action. , ,A friend goes on ...
... at a Senate appearance earlier this year. Credit: U.S. ... and Human Services Secretary Tommy Thompson announced Wednesday the ... national health information infrastructure in 10 years and bring ... also released a report, prepared by National Health IT ...
Cached Biology Technology:Five ways your company can benefit from patent searches 2Five ways your company can benefit from patent searches 3'Don't work here' job interviews set new Midwest technology trend 2'Don't work here' job interviews set new Midwest technology trend 3'Don't work here' job interviews set new Midwest technology trend 4'Don't work here' job interviews set new Midwest technology trend 5Thompson announces 'Decade of Health Information Technology' 2Thompson announces 'Decade of Health Information Technology' 3Thompson announces 'Decade of Health Information Technology' 4Thompson announces 'Decade of Health Information Technology' 5Thompson announces 'Decade of Health Information Technology' 6
Identify and characterize Phosphoinositide (PI(3,4,5)P3) binding...
Anti-Human alpha2-Antiplasmin Purified (Polyclonal) (goat IgG)...
Volume adapter mounts on top of the 96 well FiltrEX filter plate and allows larger volumes (1mL) to be applied to each well in a filter plate. Adapters are nonsterile....
... The Mini-PROTEAN 3 Dodeca cell with multi-casting chamber ... up to 12 mini format handcast (8.3 x ... gels. The cell requires 3.4-4.4 L of buffer ... coil that attaches to an external refrigerated circulator ...
Biology Products: