Navigation Links
Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
Date:3/14/2012

Recent breakthroughs in Chikungunya research spearheaded by scientists at A*STAR's Singapore Immunology Network (SIgN) have made great strides in the battle against the infectious disease. Working in close collaborations with Singapore clinician-scientists and international researchers , Dr Lisa Ng, Principal Investigator of the Chikungunya research group at SIgN, led the team to discover a direct biomarker which serves as an early and accurate prognosis of patients who have a higher risk of the more severe form of Chikungunya fever (CHIKF). This means that doctors can now quickly and accurately identify patients at risk, facilitating a more targetted treatment and clinical care at the onset of the disease.

Chikungunya fever, caused by the Chikungunya virus (CHIKV) , is a mosquito-borne, infectious disease endemic to Southeast Asia and Africa. Since its re-emergence in 2005, CHIKV infection has spread to nearly 20 countries to infect millions . Singapore, for instance, was hit twice by Chikungunya fever outbreaks in January and August 2008.

CHIKV infection is characterised by an abrupt onset of fever frequently accompanied by severe muscle and joint pains. Though most patients recover fully within a week, in severe cases, the joint pains may persist for months, or even years. For individuals with a weak immune system, the disease can result in death. With no clinically-approved vaccine or treatment for Chikungunya fever, it remains a worrying public health problem.

To devise strategies to stop CHIKV transmission, Dr Ng's team collaborated with Professor Leo Yee Sin and Dr Angela Chow, clinician-scientists from the Communicable Disease Centre (CDC) at Tan Tock Seng Hospital , to study how the human body responds to CHIKV infection. The team conducted a comprehensive study on the antibody response against CHIKV in patients. They discovered that patients who respond to the disease at the onset with high levels of Immunoglobulin G3
'/>"/>

Contact: Dr. Sarah Chang KC
chang_kai_chen@a-star.edu.sg
65-682-66442
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

Page: 1 2

Related biology news :

1. DOE researchers achieve important genetic breakthroughs to help develop cheaper biofuels
2. Argonne scientists awarded supercomputing time to enable scientific breakthroughs
3. IEEE-USA cites 5 engineering breakthroughs
4. Understanding global climate change through new breakthroughs in polar research
5. Bio-optics breakthroughs: Highlights of medical and bioscience research at Frontiers in Optics 2009
6. Key to future medical breakthroughs is systems biology, say leading European scientists
7. Experimental vaccine protects monkeys against chikungunya
8. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
9. Scripps Research discoveries lead to newly approved drug for infant respiratory distress syndrome
10. A project to research biological and chemical aspects of microalgae to fuel approach
11. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/7/2014)... Calif. , Nov. 7, 2014  In conjunction with ... Police Departments, The Community Foundation of the Verdugos ... DNA JUSTICE PROJECT," a $250,000 initiative to keep ... initial phase. In its first six months of existence, the ... needed evidence support for local law enforcement. "Because ...
(Date:11/6/2014)... occur because of metastasis, yet progress in preventing ... , "It,s been particularly challenging to design drugs ... fellow in systems biology at Harvard Medical School. ... after they,ve already metastasized." , Gujral and colleagues ... help researchers better understand how metastasis begins. Their ...
(Date:11/5/2014)... in the UTSA College of Sciences, is one ... receive a two-year $300,00 National Science Foundation (NSF) ... funding supports President Obama,s BRAIN Initiative, a federal ... that will demystify complex brain processes. , ... broken into the interactions of multiple components, each ...
Breaking Biology News(10 mins):Community Foundation Of The Verdugos Unveils Campaign To Fund Glendale-Burbank DNA Justice Project 2Migration negation 2Migration negation 3UTSA biology professor awarded $300,000 NSF grant for brain research 2UTSA biology professor awarded $300,000 NSF grant for brain research 3
... been honored by the National Science Foundation with a ... with microfluidic devices, which promise to improve 3D tissue ... University of Texas College of Engineering in 2007, has ... tissue and cells on microchips. , Her devices produce ...
... The Federation of American Societies for Experimental Biology ... inaugural advocacy competition, Stand Up for Science. The competition ... the health, quality of life, or economy of local ... submitted by ,Stand With Science, a group of graduate ...
... the amphibians and reptiles of Sierra Madre Mountain Range, ... 100 species that contribute to the unique biodiversity of the region. ... more than 150 species. Out of these, a total of 49 ... a remarkable 32 endemic. In the world of reptiles, Luzon can ...
Cached Biology News:The amazing amphibians and reptiles of the Philippine island Luzon 2
(Date:11/22/2014)... -- The element of surprise has been a major advantage ... warning. Until now, epidemiologists had nothing to measure that ... in suboptimal responses to both the H1N1 pandemic of ... - http://photos.prnewswire.com/prnh/20141121/160242 That virus ... gene structural changes have been found that invariably to ...
(Date:11/21/2014)... (PRWEB) November 19, 2014 The science ... lives was shared with more than 200 primary students ... students from the University of Otago Physics Department and ... The Otago students, members of the university’s OSA/SPIE Student ... in early September, giving children from small, rural schools ...
(Date:11/21/2014)... The report, "Synthetic Biology Market by ... Technology (Bioinformatics, Nanotechnology, Gene Synthesis, Cloning & ... Global Forecast to 2018", analyses and studies ... challenges. , Browse 99 market data tables ... and in-depth TOC of the global synthetic ...
(Date:11/21/2014)... November 21, 2014 2014 Deep ... Industry” is a professional and in-depth research report ... ferrocyanide information, like its definition, classification, application, ... overview. This report covers the international market analysis, ... (such as the US, Europe, Asia, China, Japan ...
Breaking Biology Technology:Viruses' Advantage of Surprise is Lost 2Optics and photonics outreach programs share science, spark fascination with light 2Optics and photonics outreach programs share science, spark fascination with light 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 2Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 4Sodium Ferrocyanide Market: Analysis for Global & China Regions Development Trends Available at DeepResearchReports.com 2Sodium Ferrocyanide Market: Analysis for Global & China Regions Development Trends Available at DeepResearchReports.com 3
... BHRT ) a company committed to delivering ... treat heart failure and,cardiovascular diseases, today announced financial ... Recent Clinical Highlights:, -- On July ... a preclinical,study involving the injection of myoblasts modified ...
... adaptive and assistive technology, MIDDLETOWN, NY and ... of the world,s first commercially available bionic hand,today ... 2008 da Vinci Award from the,National Multiple Sclerosis ... most innovative developments and,research in adaptive and assistive ...
... RICHMOND, Texas, July 30 DNA Heritage has recently,overcome ... severely,restricted the use of DNA testing and databases that ... through their DNA. The patent covers the,use of surnames ... Property Office (UK IPO) has now rendered a formal ...
Cached Biology Technology:Bioheart, Inc. Announces Financial Results for Second Quarter 2008 2Bioheart, Inc. Announces Financial Results for Second Quarter 2008 3Bioheart, Inc. Announces Financial Results for Second Quarter 2008 4Bioheart, Inc. Announces Financial Results for Second Quarter 2008 5Bioheart, Inc. Announces Financial Results for Second Quarter 2008 6Bioheart, Inc. Announces Financial Results for Second Quarter 2008 7Touch Bionics a 2008 da Vinci Award winner 2DNA Heritage Success in Patent Battle Helps Keep Genealogy DNA Test Prices Low 2
PI/RNase Staining Buffer Solution , 100 ml Consult technical datasheet for details....
Macrophage-stimulating protein receptor...
Mouse monoclonal [3B6] to HSV1 + HSV2 ICP5 Major Capsid Protein ( Abpromise for all tested applications)....
...
Biology Products: