Navigation Links
Breakthrough technology focuses in on disease traits of single cells
Date:7/24/2012

Just like populations of human beings, clusters of living cells are made up of individuals possessing unique qualities. Traditional analytic techniques however evaluate cells in tissue aggregates, often overlooking single-cell nuances that can offer valuable clues concerning health and disease.

ASU Senior Scientist and Professor, Deirdre Meldrum, and her colleagues at Arizona State University's Biodesign Institute are pioneering a kind of miniaturized laboratory for the investigation of single cells. Known as the Cellarium, this live cell array technology will enable researchers to investigate the detailed behavior of individual cellsproviding unprecedented insights into their role in disease processes.

"Just as an aquarium is for viewing and studying live fish, the 'Cellarium' is for viewing and studying live cells," Meldrum says. "The Cellarium is an innovative, disposable microarray with sensors for dynamic, high-throughput measurements of live single cells. It is capable of multiparameter metabolic measurements of biosignatures induced by perturbation," she explains.

Currently under a $1.5 million grant from the NIH, the Cellarium project is the fruit of over a decade of scientific progress. Much of this work has been carried out with Meldrum's Center for Biosignatures Discovery Automation, a multidisciplinary team Meldrum directs and that has devoted significant resources to the study of single-cell physiology. Other key investigators in the Cellarium project include Drs. Honor Glenn, Mark Holl, Laimonas Kelbauskas, Yanqing Tian, Cody Youngbull, and Mr. Cliff Anderson.

An NIH Center of Excellence in Genomic Sciences known as the Microscale Life Sciences Center at Biodesign, also directed by Meldrum, has created and developed the Cellarium's early generation technology, with the assistance of partners at the University of Washington, Fred Hutchinson Cancer Research Center, and Brandeis University.

The new gr
'/>"/>

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Research breakthrough: High brain integration underlies winning performances
2. NTU researchers study little mighty creature for scientific breakthrough
3. Nanotechnology breakthrough could dramatically improve medical tests
4. WanderID Launches Breakthrough ID Product for Children, Seniors
5. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
6. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
7. University of Tennessee Space Institute researchers develop laser technology to fight cancer
8. Geosphere: How geology, technology, modeling, and mapping see into Earths past and present
9. RIH study: Emergency patients prefer technology-based interventions for behavioral issues
10. Engineering technology reveals eating habits of giant dinosaurs
11. Security Technology Executive, SIA and ISC East announce Security Innovation Awards Collaboration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breakthrough technology focuses in on disease traits of single cells
(Date:12/17/2014)... Dec. 16, 2014  Automation is fundamentally transforming the travel ... international borders. Over the past decade, ePassports, biometric readers, ... self process through border control via eGates and Automated ... airports, seaports, and land borders across the globe. ...
(Date:12/11/2014)... , Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of ...  report to their offering. One major ... With continuous advances in technology, it is important to ...
(Date:12/11/2014)...  That blood pressure plays a role in human health has ... term for high blood pressure – was first described as ... that,s used in measuring blood pressure was invented in 1896. ... hypertension, its triggers and its effects. In fact, recent findings ...
Breaking Biology News(10 mins):Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... ways of exchanging informationmonkeys vocalize complex messages, ants create ... bellies to attract mates. Yet, despite the fact that ... on the planet, little is known about the way ... Technology (Caltech) biologists has shown that a wide range ...
... ocean temperatures rise, some species of corals are likely to ... published online on April 12 in the Cell Press journal ... of climate effects on corals. "The good news is ... survive climate change by changing the mix of coral species ...
... have evolved along with intelligence as a beneficial ... at SUNY Downstate Medical Center and other institutions. ... Downstate, and colleagues found that high intelligence and ... the depletion of the nutrient choline in theGlaxoSmithKline ...
Cached Biology News:Decoding worm lingo 2Decoding worm lingo 3Under climate change, winners and losers on the coral reef 2Excessive worrying may have co-evolved with intelligence 2
(Date:1/22/2015)... 22, 2015 Pipette.com has added the ... their comprehensive portfolio of Eppendorf products. , The Eppendorf ... a Centrifuge 5424/5424 R and receive the following:, ... Research plus or Eppendorf Reference 2 , ...
(Date:1/22/2015)... DE (PRWEB) January 22, 2015 Controlled ... Pistoia Alliance, which helps companies check the legal requirements ... to expand to China. , As their international ... are globally adopting software solutions built as a result ...
(Date:1/22/2015)... Nueva Jersey , 22 de enero de 2015  El ... abre hoy su llamada a nominaciones para 2015. Este ... ha hecho, o tiene el potencial para hacer, contribuciones ... nominaciones se aceptarán hasta el 15 de marzo de ...
(Date:1/22/2015)...   GenoSpace , a precision medicine software company that has ... use of genomic, imaging and other biomedical data in research ... Munson , CEO of Aspera, an IBM Company, to its ... http://photos.prnewswire.com/prnh/20150122/170713 "We are pleased to welcome ...
Breaking Biology Technology:Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Global Compliance Service for Controlled Substances to Expand to China 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4GenoSpace Expands Board with Appointment of Michelle Munson 2
... Lead Discovery, COPENHAGEN, June 18 Nuevolution ... drug discovery collaboration with Merck & Co.,Inc., ... to identify novel small molecule leads against several ... uses innovative DNA,labeling to allow fragment-based drug screening ...
... HARTFORD, Conn., June 17 The Connecticut,Technology Council (CTC) ... in,partnership with accounting firm UHY LLP this November, to ... will be,recognized on the basis of revenue growth over ... and minimum revenues of $3 million in,the fourth year., ...
... Edwards Lifesciences,Corporation (NYSE: EW ), a world ... disease, is scheduled to participate in the,18th Annual ... in Nantucket, Massachusetts on Tuesday, June 24, 2008., ... president, chief,financial officer & treasurer, is scheduled to ...
Cached Biology Technology:Nuevolution Announces Research and Development Collaboration with Merck & Co. Inc. 2Connecticut Technology Council to Recognize Fast Growing Technology Companies 2Edwards Lifesciences to Present at the 18th Annual Wachovia Nantucket Equity Conference 2
... -mr agarose is specifically for ... endoosmosis, and is recommended for ... weight proteins or complexes that ... of molecular sieving in polyacrylamide ...
... Sequi-Gen GT and PowerPac 3000 system, 220-240 V, ... 38 x 50 cm vertical slab gel format. ... cell, which is capable of separating nucleic acids ... plate chamber (IPC) assembly (IPC and bonded inner ...
... 2-color staining method for labeling DNA breaks ... cells by flow cytometry. The kit contains ... apoptosis in cells including positive and negative ... reaction and rinsing buffers for processing individual ...
The stirbar is used in the buffer tank of the Trans-Blot Plus cell to maintain uniform conductivity and temperature during electrophoretic transfer. Dimensions are 3.5 x 0.5 in....
Biology Products: