Navigation Links
Breakthrough technology focuses in on disease traits of single cells
Date:7/24/2012

Just like populations of human beings, clusters of living cells are made up of individuals possessing unique qualities. Traditional analytic techniques however evaluate cells in tissue aggregates, often overlooking single-cell nuances that can offer valuable clues concerning health and disease.

ASU Senior Scientist and Professor, Deirdre Meldrum, and her colleagues at Arizona State University's Biodesign Institute are pioneering a kind of miniaturized laboratory for the investigation of single cells. Known as the Cellarium, this live cell array technology will enable researchers to investigate the detailed behavior of individual cellsproviding unprecedented insights into their role in disease processes.

"Just as an aquarium is for viewing and studying live fish, the 'Cellarium' is for viewing and studying live cells," Meldrum says. "The Cellarium is an innovative, disposable microarray with sensors for dynamic, high-throughput measurements of live single cells. It is capable of multiparameter metabolic measurements of biosignatures induced by perturbation," she explains.

Currently under a $1.5 million grant from the NIH, the Cellarium project is the fruit of over a decade of scientific progress. Much of this work has been carried out with Meldrum's Center for Biosignatures Discovery Automation, a multidisciplinary team Meldrum directs and that has devoted significant resources to the study of single-cell physiology. Other key investigators in the Cellarium project include Drs. Honor Glenn, Mark Holl, Laimonas Kelbauskas, Yanqing Tian, Cody Youngbull, and Mr. Cliff Anderson.

An NIH Center of Excellence in Genomic Sciences known as the Microscale Life Sciences Center at Biodesign, also directed by Meldrum, has created and developed the Cellarium's early generation technology, with the assistance of partners at the University of Washington, Fred Hutchinson Cancer Research Center, and Brandeis University.

The new gr
'/>"/>

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Research breakthrough: High brain integration underlies winning performances
2. NTU researchers study little mighty creature for scientific breakthrough
3. Nanotechnology breakthrough could dramatically improve medical tests
4. WanderID Launches Breakthrough ID Product for Children, Seniors
5. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
6. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
7. University of Tennessee Space Institute researchers develop laser technology to fight cancer
8. Geosphere: How geology, technology, modeling, and mapping see into Earths past and present
9. RIH study: Emergency patients prefer technology-based interventions for behavioral issues
10. Engineering technology reveals eating habits of giant dinosaurs
11. Security Technology Executive, SIA and ISC East announce Security Innovation Awards Collaboration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breakthrough technology focuses in on disease traits of single cells
(Date:4/17/2014)... Our eyes not ... with a continuous stream of information about our own movements. ... a car the world glides by us and leaves ... our brain calculates self-motion from this "optic flow". This way, ... during our own movements. Together with biologists from the University ...
(Date:4/17/2014)... hydrogen sulfide in order to properly multiply and form ... Center for Craniofacial Molecular Biology at the Herman Ostrow ... principal investigator on the project, said the presence of ... of calcium ions. The essential ions activate a chain ... creation of new bone tissue, and keeps the breakdown ...
(Date:4/17/2014)... Rajendra Singh Thursday as a "Champion of Change" ... deployment in the residential, commercial and industrial sectors. ... Electrical and Computer Engineering and director of Clemson,s ... hero leading the charge across the country to ... and driving policy changes at the local level ...
Breaking Biology News(10 mins):How vision makes sure that little fish do not get carried away 2How vision makes sure that little fish do not get carried away 3How vision makes sure that little fish do not get carried away 4White House honors Clemson professor as 'Champion of Change' for solar deployment 2
... not the most hospitable place on Earth, but at least ... The bacteria -- Chryseobacterium and Paenisporosarcina ... the laboratory that was designed to simulate as closely as ... of Arctic and Antarctic glaciers, said Corien Bakermans, assistant professor ...
... in which a key cell of the immune system prepares ... processes that take place within these cells and could lead ... cancer. The research focused on the neutrophil, the most ... the immune system, its job is to seek out and ...
... canines were on a mission to sniff out trouble ... of an Office of Naval Research (ONR)-hosted "Top Dog ... by helping them move through the battle space," said ... Program, part of ONR,s Expeditionary Warfare and Combating Terrorism ...
Cached Biology News:Hardy bacteria help make case for life in the extreme 2UCSF team uncovers how immune cells move against invaders 2Marine's best friend shows explosive-detecting capabilities 2
(Date:1/15/2014)... England , January 15, 2014 A ... win races on the Formula 1 track could help to ... McLaren Applied Technologies (MAT), Stowhealth (a GP surgery based in ... by healthcare provider Simplyhealth. Telemetry technology, which is ...
(Date:1/15/2014)... NY (PRWEB) January 15, 2014 The Microcompetition ... a major disease. One of these latent viruses is the ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic inflammatory ... theory, a study found that RA patients have high concentrations ...
(Date:1/15/2014)... CA (PRWEB) January 15, 2014 ... research solutions, today announced that Lupin Limited, one of ... Freeslate’s CM Protégé PharmD System for high ... Mumbai, India, is focused on a wide range of ...
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: ... 1360 Almshouse Road, Warrington, Pa. , Details: The ... to finding a cure for hepatitis B and improving the ... annual Crystal Ball on Friday, April 11 at Warrington Country ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2
... tickles your feet or the red Bordeaux smacking on your ... special chemical markers. These markers, called isotopes, can tell scientists ... they traveled, and what happened to them along the way. ... Stanford chemists have developed a new method to make isotopic ...
... PROMOTIONAL SYSTEMS, INC. (Pink Sheets: VGPR) today announced it has ... to assist the Company in building a biomass production facility ... its intention to build a biomass plant in Georgia to ... State,s Bioenergy Corridor. Georgia ranks third in the nation ...
... Inc. (Nasdaq: NVAX ) announced today its ... vaccine technology to ROVI Pharmaceuticals (Madrid: ROVI) of Spain. ... a comprehensive influenza vaccine solution for the Spanish government ... by the Spanish Ministry of Health and other government ...
Cached Biology Technology:Stanford researchers find a quicker, cheaper way to sort isotopes 2Stanford researchers find a quicker, cheaper way to sort isotopes 3Vega Picks Tennessee Firm to Assist with Construction of Biomass Plant in Georgia 2Spanish Government Selects Novavax's VLP Technology for Comprehensive Flu Vaccine Solution in Spain 2Spanish Government Selects Novavax's VLP Technology for Comprehensive Flu Vaccine Solution in Spain 3Spanish Government Selects Novavax's VLP Technology for Comprehensive Flu Vaccine Solution in Spain 4Spanish Government Selects Novavax's VLP Technology for Comprehensive Flu Vaccine Solution in Spain 5
CircuLex Anti-Human S100P Polyclonal Antibody Research Focus: proliferation Storage: -20C Shipping Temperature: 4C...
...
Raised to arginine vasopressin coupled to bovine thyroglobulin with carbodiimide ....
Anti-LC3 Polyclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Biology Products: