Navigation Links
Breakthrough technology focuses in on disease traits of single cells
Date:7/24/2012

Just like populations of human beings, clusters of living cells are made up of individuals possessing unique qualities. Traditional analytic techniques however evaluate cells in tissue aggregates, often overlooking single-cell nuances that can offer valuable clues concerning health and disease.

ASU Senior Scientist and Professor, Deirdre Meldrum, and her colleagues at Arizona State University's Biodesign Institute are pioneering a kind of miniaturized laboratory for the investigation of single cells. Known as the Cellarium, this live cell array technology will enable researchers to investigate the detailed behavior of individual cellsproviding unprecedented insights into their role in disease processes.

"Just as an aquarium is for viewing and studying live fish, the 'Cellarium' is for viewing and studying live cells," Meldrum says. "The Cellarium is an innovative, disposable microarray with sensors for dynamic, high-throughput measurements of live single cells. It is capable of multiparameter metabolic measurements of biosignatures induced by perturbation," she explains.

Currently under a $1.5 million grant from the NIH, the Cellarium project is the fruit of over a decade of scientific progress. Much of this work has been carried out with Meldrum's Center for Biosignatures Discovery Automation, a multidisciplinary team Meldrum directs and that has devoted significant resources to the study of single-cell physiology. Other key investigators in the Cellarium project include Drs. Honor Glenn, Mark Holl, Laimonas Kelbauskas, Yanqing Tian, Cody Youngbull, and Mr. Cliff Anderson.

An NIH Center of Excellence in Genomic Sciences known as the Microscale Life Sciences Center at Biodesign, also directed by Meldrum, has created and developed the Cellarium's early generation technology, with the assistance of partners at the University of Washington, Fred Hutchinson Cancer Research Center, and Brandeis University.

The new gr
'/>"/>

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Research breakthrough: High brain integration underlies winning performances
2. NTU researchers study little mighty creature for scientific breakthrough
3. Nanotechnology breakthrough could dramatically improve medical tests
4. WanderID Launches Breakthrough ID Product for Children, Seniors
5. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
6. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
7. University of Tennessee Space Institute researchers develop laser technology to fight cancer
8. Geosphere: How geology, technology, modeling, and mapping see into Earths past and present
9. RIH study: Emergency patients prefer technology-based interventions for behavioral issues
10. Engineering technology reveals eating habits of giant dinosaurs
11. Security Technology Executive, SIA and ISC East announce Security Innovation Awards Collaboration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breakthrough technology focuses in on disease traits of single cells
(Date:8/22/2014)... is available in French . ... essential nutrients from African soils looming as a major threat ... today finds that over the last five years, 1.7 million ... have rejuvenated 1.6 million hectares and helped them double or ... for a Green Revolution in Africa (AGRA) focuses on intensive ...
(Date:8/22/2014)... Bethesda, MD FASEB MARC (Maximizing Access to Research ... the FASEB Grant Writing Seminar & Practical Exercises Workshop ... in Bethesda, Maryland from August 25-26, 2014. These ... postdoctorates and research scientists from underrepresented groups in the ... This year MARC conferred 11 awards totaling $20,350. ...
(Date:8/22/2014)... discoveries in basic and clinical research and technological ... a complex offensive spanning multiple fronts. , Work ... could help find new and more selective therapies ... targets a specific enzyme overexpressed in certain cancersand ... brain tumours. , Chemistry professor Christopher Cairo and ...
Breaking Biology News(10 mins):Effort to confront Africa's soil health crisis helps millions of farmers triple yields 2Effort to confront Africa's soil health crisis helps millions of farmers triple yields 3Effort to confront Africa's soil health crisis helps millions of farmers triple yields 4New enzyme targets for selective cancer therapies 2New enzyme targets for selective cancer therapies 3
... international research consortium has sequenced the genome of the ... Dec. 26 advance online edition of the journal ... possibilities for breeding tastier, hardier varieties of the berry ... the strawberry parts list," said the consortium,s leader Kevin ...
... COLLEGE PARK, Md. The latest success of Martek ... a decade ago in a plain, brick building on ... and early-stage nurturing from the university,s Maryland Technology Enterprise ... into a major international business. On December ...
... University of Arizona researchers may have found a way ... doses without harming healthy body cells. If successful, ... effective to destroy cancer cells and alleviate the harmful ... The invention by Marek Romanowski, an associate professor of ...
Cached Biology News:Georgia Tech team helps decode newly sequenced strawberry genome 2Georgia Tech team helps decode newly sequenced strawberry genome 3Tech firm joins the 'billion dollar club' -- with university help 2Tech firm joins the 'billion dollar club' -- with university help 3Invention could improve cancer drug delivery, lessen harmful effects of chemotherapy 2Invention could improve cancer drug delivery, lessen harmful effects of chemotherapy 3Invention could improve cancer drug delivery, lessen harmful effects of chemotherapy 4
(Date:8/22/2014)... Research and Markets has announced the addition ... Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - ... The global molecular biology enzymes market was ... to grow at a CAGR of 13.74% to reach ... reagents find applications in a large number of fields ...
(Date:8/22/2014)... (PRWEB) August 22, 2014 The ... model organisms can be accelerated by exome sequencing. ... manufacturing technologies, the custom SeqCap EZ Developer system ... , Mr. Watson will additionally present how he ... commercially available human and mouse exome kits. With ...
(Date:8/21/2014)... 21, 2014 DNA vaccine pioneer ... its development of JRC-LAMP-vax, an innovative and safe potential ... IC studies began this month in Hawaii, moving the ... , The Japanese red cedar releases pollen that causes ... Mountain Cedar pollen wreaks similar havoc in Colorado, New ...
(Date:8/21/2014)... August 21, 2014 2014 ... Industryā€¯ is a professional and in-depth research ... report provides basic Seaweed Fertilizer information, including ... chain structure as well as industry overview. ... including domestic market as well as global ...
Breaking Biology Technology:Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 2Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 3Efficient Identification of Protein-Coding Variants in a Model Organism Through Exome Sequencing, New Webinar Hosted by Xtalks 2Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 2Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 3Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 4Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 3
... GE Healthcare said it has installed its first volume ... be used exclusively by a cardiologist. , ,Round Rock Cardiology ... patients' hearts and nearby arteries. GE said the scans take ... 64 images, LightSpeed builds up a three-dimensional view. , ,The ...
... Thompson, former U.S. Health and Human Services secretary and ... executive positions since leaving his Cabinet post in January. ... Four accounting firm Deloitte & Touche USA; law partner ... Feld; and president of La Crosse-based Logistics Health Inc., ...
... office just recently and we didn't hire him. , ,It was a ... when he came to the interview: "Tell us what you know about ... just now, I am excited to learn more." A big, silent gong ... a prospective employer for anyone to fail to do so. Midwest technology ...
Cached Biology Technology:Tommy Thompson tackles the private sector in spades 2Hone your pre-interview skills or you may lose that tech job 2Hone your pre-interview skills or you may lose that tech job 3Hone your pre-interview skills or you may lose that tech job 4Hone your pre-interview skills or you may lose that tech job 5
...
... Deacetylase (HDAC) Antibody Sampler Kit Kit ... Catalog #2062, 40 ul Histone Deacetylase 3 ... Deacetylase 4 (HDAC4) Antibody, Catalog #2072, 40 ... #2082, 40 ul Histone Deacetylase 6 (HDAC6) ...
Recombinant Mouse Matrilin-4, CF Protein Family: Extracellular Matrix Molecules, Chondrogenesis Markers...
Immunogen: Synthetic Peptide: C N(185) D G T E F G G S I Y Q K(197) Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biology Products: