Navigation Links
Blue light used to harden tooth fillings stunts tumor growth
Date:6/24/2008

A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say.

"The light sends wavelengths of blue-violet light to the composite, which triggers hardening," says Alpesh Patel, a rising MCG School of Dentistry junior. "The light waves produce free radicals that activate the catalyst and speed up polymerization of the composite resin. In oral cancer cells, though, those radicals cause damage that decreases cell growth and increases cell death."

Mr. Patel, who has been working with Dr. Jill Lewis, associate professor of oral biology, Dr. Regina Messer, associate professor of oral rehabilitation and oral biology, and Dr. John Wataha, adjunct professor of oral rehabilitation and oral biology, studied 10 tumor-bearing mice, five treated with the light and five untreated.

He exposed half the mice to the blue light for 90 seconds a day for 12 days. Then the tumors were extracted and each one was split into two sections. Half were used to create slides for tissue analysis, and half were frozen to prepare protein extracts.

Tissue analysis indicated an approximate 10 percent increase in cell suicide, or apoptosis, in the light-treated tumors. The frozen protein extracts revealed a nearly 80 percent decrease in cell growth in the light-treated tumors.

"The decrease in cell growth, combined with increased apoptosis, helps explain why the tumors didn't grow as much because you have cells that aren't dividing and you have cells that are committing suicide," Mr. Patel says.

Dr. Lewis predicts treating the tumors with blue light sooner will increase the rate of apoptosis, possibly preventing the tumor from ever becoming measurable and easing treatment.

"One desirable feature we've observed with the blue light is that non-cancerous cells appear unaffected at light doses that kill tumor cells," says Dr. Lewis. "We're thinking that some day, blue light
'/>"/>

Contact: Amy Connell
aconnell@mcg.edu
706-721-8605
Medical College of Georgia
Source:Eurekalert  

Page: 1 2

Related biology news :

1. July 2008 GEOLOGY and GSA Today media highlights
2. July 2008 highlights
3. Genome sequence of small marine creature sheds light on vertebrate origins
4. Highlights from the June 2008 Journal of the American Dietetic Association
5. New text highlights role of microorganisms in alternative energy development
6. June GEOSPHERE media highlights
7. Undergraduates develop dirt-powered microbial fuel cells to light Africa
8. UV lotion lights the way to cleaner facilities
9. Highlights from the May 2008 Journal of the American Dietetic Association
10. European light research opens door for optical storage and computing
11. Detecting dangerous chemicals with lasers, exploring the brains circuitry with light and more
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Blue light used to harden tooth fillings stunts tumor growth
(Date:3/12/2015)... March 12, 2015 WHEN:Tuesday, March 17, 2015 ... http://bit.ly/1G7Os0L . SPEAKERS: , Frost & Sullivan ... http://photos.prnewswire.com/prnh/20150311/181111 Biometric companies must ... in several different markets and industries. This is ... an uptrend. Join Frost & ...
(Date:3/10/2015)... PROVO, Utah , March 10, 2015   ... genome interpretation, has been selected by next-generation sequencing company ... provider of whole exome and targeted gene panel interpretation. ... sequencing provider, has adopted the most current technologies to ... of genetic research. The company offers two types of ...
(Date:3/2/2015)... SAN JOSE, Calif. , March 2, 2015 ... ), the leading developer of human interface solutions, ... ID technology that is designed to enable rapid ... Synaptics Natural ID™ module for gaming is a ... and ODMs the ability to quickly integrate fingerprint ...
Breaking Biology News(10 mins):Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 3PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 2PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 3Synaptics Unveils New Fingerprint ID Solution for Gamers 2Synaptics Unveils New Fingerprint ID Solution for Gamers 3
... A family of biodegradable polymers called polyketals and their ... acute lung injury, acute liver failure and inflammatory bowel ... acid to disease locations in the body. "The ... get the drugs inside the body to the diseased ...
... PhD, Associate Professor of Neuroscience at LSU Health Sciences ... only naturally occurring fatty acids in the brain ... originally identified as the targets of THC (the psychoactive ... from neurodegenerative diseases like Alzheimer,s and Parkinson,s. Published in ...
... issue of the Journal of Lipid Research suggests ... the rising rate of diabetes, especially in children and young ... mechanism of inheritance; kids get half their genes from mom ... understand additional kinds of inheritance like metabolic programming, which occurs ...
Cached Biology News:Biodegradable polymers show promise for improving treatment of acute inflammatory diseases 2Biodegradable polymers show promise for improving treatment of acute inflammatory diseases 3LSUHSC research reports new method to protect brain cells from diseases like Alzheimer's 2
(Date:3/27/2015)... The consumption of compound fertilizers (NPK) fertilizers ... high prices in 2008. However, the situation has stabilised ... gaining momentum now. , To date, the world annual ... thousand tonnes. No considerable growth was registered in the ... during 2012-2013, registering 11% growth as against the period ...
(Date:3/27/2015)... Mich. , March 27, 2015  Neogen Corporation ... LLC, has adopted a prearranged trading plan in accordance ... Herbert , Chairman and CEO of Neogen Corporation, is ... of Neogen Corporation common stock. Herbert does ... disclosure was appropriate. The filing is only for a ...
(Date:3/27/2015)... March 27, 2015  Peter Walter was chosen as ... his pioneering work on how proteins are transported between ... regulatory mechanism that cells use to handle stress tied ... a professor of biochemistry at the University of California, ... a range of human diseases related to defective protein ...
(Date:3/27/2015)... , March 27, 2015 WuXi ... leading open-access R&D capability and technology platform company ... industries, announced today that an Investigational New Drug ... antibody for rheumatoid arthritis has been accepted for ... (CFDA).  In September 2012, MedImmune, ...
Breaking Biology Technology:World NPK Fertilizers Market Keeps On Gaining Momentum, According to BAC Reports Study Available at MarketPublishers.com 2World NPK Fertilizers Market Keeps On Gaining Momentum, According to BAC Reports Study Available at MarketPublishers.com 3Neogen CEO adopts 10b5-1 Trading Plan 2German-born cell biologist Peter Walter wins the 2015 Vilcek Prize in Biomedical Science 2German-born cell biologist Peter Walter wins the 2015 Vilcek Prize in Biomedical Science 3Investigational New Drug Application for WuXi MedImmune's Monoclonal Antibody Accepted for Review by CFDA 2Investigational New Drug Application for WuXi MedImmune's Monoclonal Antibody Accepted for Review by CFDA 3
... MEETING, Pa., Dec. 1 /PRNewswire-Asia-FirstCall/ -- BMP Sunstone,Corporation (Nasdaq: ... today announced,that the company will attend the 20th Annual ... The 20th Annual Piper Jaffray Health Care ... Wednesday, December 3, 2008, at the New York,Palace Hotel ...
... /PRNewswire-Asia/ -- China Medicine Corporation,(OTC Bulletin Board: ... leading,developer and distributor of prescription and over ... and dietary supplements, and,medical devices and medical ... GSP (Good Supply Practice for Pharmaceutical Products) ...
... /PRNewswire-Asia/ -- Tigermed Consulting Co., Ltd,a leading ... that it has,established a subsidiary, Hunan Tigermed ... University (CSU). The establishment of ... of a nationwide first-rate Phase,I Clinical Laboratory, ...
Cached Biology Technology:China Medicine Corporation Awarded GSP Certification 2China Medicine Corporation Awarded GSP Certification 3Tigermed Sets Up Subsidiary, Hunan Tigermed Xiangya Drug R&D Ltd (Tigermed Xiangya) 2
Mouse polyclonal antibody raised against a partial recombinant KCTD13. NCBI Entrez Gene ID = 253980...
... selection system for recombinant identification. Recombinant selection ... need for costly color screening. This quick ... accuracy in recombinant selection. pLivSelect is also ... This cloning kit is customized as ...
Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP). [Source:Uniprot/SWISSPROT;Acc:P08697] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Mouse monoclonal antibody raised against a partial recombinant ZNF167. NCBI Entrez Gene ID = ZNF167...
Biology Products: