Navigation Links
Blue light used to harden tooth fillings stunts tumor growth
Date:6/24/2008

A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say.

"The light sends wavelengths of blue-violet light to the composite, which triggers hardening," says Alpesh Patel, a rising MCG School of Dentistry junior. "The light waves produce free radicals that activate the catalyst and speed up polymerization of the composite resin. In oral cancer cells, though, those radicals cause damage that decreases cell growth and increases cell death."

Mr. Patel, who has been working with Dr. Jill Lewis, associate professor of oral biology, Dr. Regina Messer, associate professor of oral rehabilitation and oral biology, and Dr. John Wataha, adjunct professor of oral rehabilitation and oral biology, studied 10 tumor-bearing mice, five treated with the light and five untreated.

He exposed half the mice to the blue light for 90 seconds a day for 12 days. Then the tumors were extracted and each one was split into two sections. Half were used to create slides for tissue analysis, and half were frozen to prepare protein extracts.

Tissue analysis indicated an approximate 10 percent increase in cell suicide, or apoptosis, in the light-treated tumors. The frozen protein extracts revealed a nearly 80 percent decrease in cell growth in the light-treated tumors.

"The decrease in cell growth, combined with increased apoptosis, helps explain why the tumors didn't grow as much because you have cells that aren't dividing and you have cells that are committing suicide," Mr. Patel says.

Dr. Lewis predicts treating the tumors with blue light sooner will increase the rate of apoptosis, possibly preventing the tumor from ever becoming measurable and easing treatment.

"One desirable feature we've observed with the blue light is that non-cancerous cells appear unaffected at light doses that kill tumor cells," says Dr. Lewis. "We're thinking that some day, blue light
'/>"/>

Contact: Amy Connell
aconnell@mcg.edu
706-721-8605
Medical College of Georgia
Source:Eurekalert  

Page: 1 2

Related biology news :

1. July 2008 GEOLOGY and GSA Today media highlights
2. July 2008 highlights
3. Genome sequence of small marine creature sheds light on vertebrate origins
4. Highlights from the June 2008 Journal of the American Dietetic Association
5. New text highlights role of microorganisms in alternative energy development
6. June GEOSPHERE media highlights
7. Undergraduates develop dirt-powered microbial fuel cells to light Africa
8. UV lotion lights the way to cleaner facilities
9. Highlights from the May 2008 Journal of the American Dietetic Association
10. European light research opens door for optical storage and computing
11. Detecting dangerous chemicals with lasers, exploring the brains circuitry with light and more
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Blue light used to harden tooth fillings stunts tumor growth
(Date:12/22/2014)... 2014 Holiday Season may be the brightest ever for ... the long anticipated floodgates for consumer biometrics may finally ... phones, tablets, and wearable mobile devices that incorporate biometrics ... with nearly 4.8 billion biometric devices by 2020.   ...
(Date:12/19/2014)... Dec. 18, 2014   LaunchKey , the first decentralized ... and Internet of Things era, today announced the close ... round was led by Metamorphic Ventures with participation from ... VegasTechFund, and others.  LaunchKey has raised $4 million to ...
(Date:12/17/2014)... , Dec. 16, 2014 Valencell, a leader in ... biometric technology to industry leaders such as Intel, Jabra, ... validated, biometric wearable products. These products will be showcased ... Las Vegas . "Our ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2
... immune system defects, visual pathologies, heart disease. A ... providing an excellent model system to unravel these ... worldwide are currently working with this organism and ... health; Spain is among the leading countries for ...
... more open to the idea of "designing" babies than the ... the University of East Anglia. , The findings will be ... Science on Setpember 5. , Dr. Hampton and his team ... what different groups of people in the UK would "design ...
... discovered on an unexplored mountain range in northern ... Conservation Programme. It was named "Yariguies Brush-Finch," with ... The new brush-finch was described by an Anglo-Colombian ... and Blanca Huertas (Natural History Museum and University ...
Cached Biology News:A valuable fly for research into disease 2Designer babies - what would you do for a 'healthy' baby? 2New bird discovered on unexplored Columbian mountain 2
(Date:1/22/2015)... , Nueva Jersey , 22 de enero ... for Biomedical Research abre hoy su llamada a nominaciones ... cuya investigación científica ha hecho, o tiene el potencial ... salud humana. Las nominaciones se aceptarán hasta el 15 ...
(Date:1/22/2015)... PRINCETON, N.J. , Jan. 22, 2015  Derma ... tissue regeneration company focused on advanced wound care, ... from placental tissues, have been added to the ... announcement increases the opportunity for the AMNIOEXCEL® and ...
(Date:12/24/2014)... , Dec. 24, 2014  Vermillion, Inc. (Nasdaq:   ... disease, announced today that the Company closed its ... Investment Management, Jack W. Schuler , Birchview ... were $10.5 million, before offering expenses.  The proceeds ...
(Date:12/24/2014)... 2014 Earlier this year in a June ... the Adult Stem Cell Technology Center, LLC ( ASCTC ) ... property of adult tissue stem cells. His title “Asymmetric ... for the Future,” embodied the essence of his message to ...
Breaking Biology Technology:El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4
... question regarding man,s existence has been left unanswered by ... homosexuals don,t naturally reproduce, their gene pool is not ... survival and existence?  What if their existence served a ... we,re to believe Darwin,s laws of evolution, the mere ...
... Mass., June 14, 2011 Sensitech,s TempTale®4 (TT4) ... advanced and flexible range of configurable alarm options ... global supply chain by allowing for more precise, ... design gives users the ability to program up ...
... Merriman Capital, Inc., a wholly ... MERR ), today announced that it will serve as ... (ASX: CIR; OTCQX: CKDXY) as it begins trading on ... Circadian is an Australian biotechnology company developing innovative, ...
Cached Biology Technology:Sensitech® Inc.'s TempTale®4 Multi-Alarm Temperature Monitors Offer Highly Advanced and Flexible Range of Configurable Alarm Options 2Sensitech® Inc.'s TempTale®4 Multi-Alarm Temperature Monitors Offer Highly Advanced and Flexible Range of Configurable Alarm Options 3Merriman Capital Announces Sponsorship of Circadian Technologies on OTCQX 2Merriman Capital Announces Sponsorship of Circadian Technologies on OTCQX 3
... ultimate in utility and flexibility press-to-seal silicone ... needs of the researcher. They are available ... as sheet material that can be easily ... are autoclavable and non-cytotoxic and can be ...
Argon Calibration Source...
SHEEP ANTI ESCHERICHIA COLI...
Recombinant Rat Leptin, CF...
Biology Products: