Navigation Links
Better housing conditions for zebrafish could improve research results
Date:5/3/2012

They are also a shoaling species, which means they prefer to group together. Dr Brennan and her team predicted that the environment they were kept in would affect their stress levels and, therefore, their response in the tank diving procedure.

They tested various aspects of how the fish were housed in a series of experiments. Some were kept in large groups, some in pairs; some were allowed only visual contact with other fish and some only could only smell each other.

They found that individually housed fish spent less time on the bottom of the tank compared to their group housed colleagues.

The team also studied how the fish reacted to ethanol, which is known to have an anti-anxiety effect on zebra fish. Their results showed that fish kept on their own responded to the ethanol, but those in a group did not.

In a third experiment, the team tested the levels of cortisol - a common hormone produced when animals are under stress - of both the group and individually housed fish, and found that individually housed fish had lower levels.

In their final experiment, they examined the effects of changing the fishes' water prior to tank diving. It had no effect on individually housed fish, but appeared to affect the typical tank diving responses of the group housed individuals.

Dr Brennan believes that the way in which the zebrafish are housed plays an important factor in obtaining reliable data from tests like this, and should be considered by researchers interested in comparative models of anxiety or indeed any behavioural test in zebrafish in order to refine their approach and increase experimental power.

She adds: "Not only will publication of our results improve the reliability of zebrafish behavioural analysis, but, by demonstrating that by refining housing one can increase the power of our analysis and reduce the number of animals used, we contribute to the 3Rs aim of UK and international science poli
'/>"/>

Contact: Bridget Dempsey
b.dempsey@qmul.ac.uk
44-207-882-7927
Queen Mary, University of London
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Bigger gorillas better at attracting mates and raising young
2. Modern hybrid corn makes better use of nitrogen, study shows
3. Intensive kidney dialysis indicates better survival rates than conventional dialysis
4. Fish larvae find the reef by orienting: The earlier the better
5. Improved loblolly pines better for the environment, study finds
6. Giant squids giant eyes: The better to see hungry whales with
7. UNH researchers find African farmers need better climate change data to improve farming practices
8. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
9. New methods for better purification of wastewater
10. Iowa State, Ames Lab chemists aid study of mutated plants that may be better for biofuels
11. Sandia seeks better neural control of prosthetics for amputees
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... , April 20, 2015 The ... Glenbeigh Records Management (GRM), Ireland,s ... Dubai Islamic Bank. Having built up an impressive track record ... a leading player within the records management sector in ... to double is GCC staffbase and employ a further eight ...
(Date:4/13/2015)... -- higi, a leading cloud-based consumer engagement platform that provides ... their communities around health and wellness, announced today the ... ... convenient vehicle to receive validated health information from consumers. ... API will allow higi,s trusted partners, on a user ...
(Date:4/2/2015)... April 2, 2015 In ... by far outperforms the strongest competitors, showing outstanding ... accuracy, the system is capable of a throughput ... proves up to be ten times faster than ... runner-up performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
Breaking Biology News(10 mins):Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3
... Pauling Institute at Oregon State University have discovered yet another ... vegetables is so good for you it provides not ... complex mechanism of epigenetics. Epigenetics, an increasing focus of ... code, but also to the way that diet, toxins and ...
... cognitive development is not generally impacted by how much ... to a study from Nationwide Children,s Hospital. This ... the widest range of confounding factors when directly examining ... Insufficient or excessive weight gain in pregnancy ...
... cancer in Northern Ireland, the number of people surviving the ... Each year there are between 50-60 men and ... would have died. The survival rates in Northern Ireland ... in the UK, and its patients are benefiting from improved ...
Cached Biology News:Another mechanism discovered by which sulforaphane prevents cancer 2Gestational weight gain generally does not influence child cognitive development 2More people surviving cancer in Northern Ireland 2
(Date:5/21/2015)... , May 21, 2015  Susan Hedstrom, ... (FPWR), a nonprofit organization dedicated to supporting research ... syndrome (PWS), announced today that FPWR has received ... Irina Shaulov contributed $1 million in ... initiatives.  "Our ...
(Date:5/21/2015)... (PRWEB) May 21, 2015 W. ... its manufacturing facility in Worms, Germany has received ... independent subsidiary of the International Pharmaceutical Excipient Council ... facilities that produce its SYLOID® FP brand of ... GMP certification, following the Curtis Bay, Maryland (USA) ...
(Date:5/21/2015)... , May 21, 2015 /PRNewswire/ - RepliCel Life ... stage regenerative medicine company focused on the development ... poster presentation at the International Society for Cellular ... chronic Achilles tendinosis currently in a Phase 1/2 ... 29 th from 5:30 PM to 7:00 ...
(Date:5/20/2015)... May 20, 2015 This year has ... for lawns. US Patented Pearl’s Premium Ultra Low ... around the country that are coming out of record ... a number of major global concerns related to water, ... grass – the alternative to the standard, water-wasting, chemical-treated ...
Breaking Biology Technology:The Foundation for Prader-Willi Research Receives $1M Contribution in Support of Clinical Initiatives 2Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel 2RepliCel to Present Unique Autologous Cell Treatment for Achilles Tendinosis at International Society for Cellular Therapy Conference 2RepliCel to Present Unique Autologous Cell Treatment for Achilles Tendinosis at International Society for Cellular Therapy Conference 3Breakthrough 4th Generation Low Maintenance Lawn Seed Offers Solution to California Drought 2
... 9 A homegrown New Jersey company is,earning ... of pharmaceuticals everywhere. Secure Symbology, (http://www.securesymbology.com ), a ... an,Honored Finalist as Emerging Business of the Year ... its vision to wipe out counterfeit drugs,worldwide. ...
... Extension Provides Members of University HealthSystem Consortium With Broad ... ... 9 Baxter International,Inc. (NYSE: BAX ) announced today ... signed a new two-year,contract extension on behalf of UHC valued ...
... Cell Therapeutics, Inc. (CTI),(Nasdaq: CTIC ; MTAX) management will present at ... pm at,the Palace Hotel in San Francisco. The conference will also ... webcast can be accessed at, http://www.cticseattle.com . ... BIO CEO & Investor Conference ...
Cached Biology Technology:Secure Symbology: Making New Jersey Proud While Saving Lives 2Baxter and Novation Sign Multi-Year Contract Extension Valued at Over $200 Million for Medication Delivery Products 2Baxter and Novation Sign Multi-Year Contract Extension Valued at Over $200 Million for Medication Delivery Products 3
... These handy dispensers save ... glasses, wipers, hats, and other ... benchtop storage bins for small ... and manufacturing. Clear acrylic. Open-slot ...
... Microarrays designed for genome-wide microRNA ... flexible and powerful Paraflo microfluidic on-chip ... as part of our comprehensive microRNA ... Content The Soil Nematode microRNA ...
... critical to the maintenance of appropriate ... as important and diverse as those ... and stress response, antigen presentation, modulation ... channels, cell cycle regulation, transcription, and ...
... Proteolytic degradation is critical to ... short-lived and regulatory proteins as important ... cellular metabolism, heat shock and stress ... surface receptors and ion channels, cell ...
Biology Products: