Navigation Links
Better housing conditions for zebrafish could improve research results
Date:5/3/2012

Changing the conditions that zebrafish are kept in could have an impact on their behaviour in animal studies and the reliability of results, according to scientists from Queen Mary, University of London.

Zebrafish, like rats and mice, are often used by neuroscientists to explore mechanisms controlling behaviour and in the search for new compounds to treat behavioural disease such as addiction, attention deficit disorders or autism.

It is known that housing and handling affects the results of behavioural studies done in rats and mice, but until now there have been few studies of how the environment the fish are kept in before they are tested can impact on the results.

Writing in the journal PLoS ONE, Dr Caroline Brennan from Queen Mary's School of Biological and Chemical Sciences explains: "Practical considerations make zebrafish a very useful species in which to explore mechanisms controlling behaviour. Their small size (less than 2 cm) and prolific breeding (approx. 300 eggs per pairing) makes it easy and cheap to keep large numbers of zebrafish in a small space. It is also relatively easy to change the zebrafish genome to explore how changes in different genes affect behaviour.

"As fish have many proteins and brain circuits in common with humans, factors that affect the fish behaviour can tell us about things that may affect human behaviour."

One of the most commonly used zebrafish behavioural tests is the 'tank diving' test that is considered a measure of the fish's stress level. When a zebrafish is placed in a new tank it shows a characteristic 'diving' response where the fish will dive to the bottom of the tank and remain there more or less stationary for a brief period of time before rising to shallower depths. The interpretation is that the longer it takes the fish to rise, the more stressed it is. This test has been suggested as a means of screening for new compounds to treat stress disorders.


'/>"/>
Contact: Bridget Dempsey
b.dempsey@qmul.ac.uk
44-207-882-7927
Queen Mary, University of London
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Bigger gorillas better at attracting mates and raising young
2. Modern hybrid corn makes better use of nitrogen, study shows
3. Intensive kidney dialysis indicates better survival rates than conventional dialysis
4. Fish larvae find the reef by orienting: The earlier the better
5. Improved loblolly pines better for the environment, study finds
6. Giant squids giant eyes: The better to see hungry whales with
7. UNH researchers find African farmers need better climate change data to improve farming practices
8. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
9. New methods for better purification of wastewater
10. Iowa State, Ames Lab chemists aid study of mutated plants that may be better for biofuels
11. Sandia seeks better neural control of prosthetics for amputees
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... data shows Africa,s Congo rainforest, the second-largest tropical rainforest ... greenness over the past decade. , The study, led ... of New York, shows between 2000 and 2012 the ... intensified. The research, published Wednesday in Nature , ... explore the effects of long-term drought on the Congo ...
(Date:4/23/2014)... of asthma, allergies and other chronic inflammatory disorders among ... part to their reduced exposure to the microbes that ... paper. , The article, published in the journal ... in urban centers who have less access to green ... a condition caused by immune system dysfunction. , When ...
(Date:4/23/2014)... German . Man ... difference between sexes depends on one single element of the genome: ... two sexual chromosomes are X and Y, whereas women have two ... morphological and physiological differences between males and females. , But this ... the X and Y were identical, until the Y started to ...
Breaking Biology News(10 mins):NASA satellites show drought may take toll on Congo rainforest 2NASA satellites show drought may take toll on Congo rainforest 3Rural microbes could boost city dwellers' health 2Rural microbes could boost city dwellers' health 3Male or female? 2Male or female? 3
... KNOXVILLE -- Research by a small group of microbiologists ... of the Earth: the realm just beneath the deep ocean ... on our planet. Beth Orcutt, a post-doctoral fellow at ... presented her new findings about this little researched realm today ...
... research studies should not be disclosed to participants without ... of the European Society of Human Genetics today (Monday). ... Policy, Management and Evaluation at the University of Toronto, ... held by many ethicists that individual genetic research findings ...
... Researchers at Rice University, Purdue University and the ... about why some fluids containing polymers -- including saliva ... do not. The findings are published online this ... Study co-author Matteo Pasquali, professor in chemical and biomolecular ...
Cached Biology News:New research into the deep ocean floor yields promising results for microbiologists 2Should the results of individual genetic studies be disclosed to participants? 2Should the results of individual genetic studies be disclosed to participants? 3Answer to saliva mystery has practical impact 2
(Date:1/15/2014)... 15, 2014   Niagara Thermal Products is proud ... BioBlower Technologies LLC ("B3") as the critical thermal component ... from the Army Corps of Engineers.  B3 has developed ... biological contaminants and destroys VOCs and other chemical pollutants, ...
(Date:1/15/2014)... This webinar will focus on EMA and FDA ... biosimilars. , Regulatory frameworks are evolving many countries to ... complex nature of biopharmaceuticals makes the demonstration of biosimilarity ... Based on the specific aspects of biosimilar drug development ...
(Date:1/15/2014)... January 15, 2014 DTS Language Services, ... Online Web Portal for Life Science organizations who need document ... the subject matter of their documents in advance with a ... reduce time-to-delivery of translations, often a critical factor in clinical ...
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: 6 ... Almshouse Road, Warrington, Pa. , Details: The Hepatitis ... finding a cure for hepatitis B and improving the quality ... Crystal Ball on Friday, April 11 at Warrington Country Club ...
Breaking Biology Technology:Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2
... , ... ... ... ...
... ... with the upside of not only producing a low sodium meat product but with ... ... manufacturer of value-added ingredients into the natural food, nutraceutical and medical food market, is ...
... ... ... ... ...
Cached Biology Technology:China Medical Technologies Reports Third Fiscal Quarter Financial Results 2China Medical Technologies Reports Third Fiscal Quarter Financial Results 3China Medical Technologies Reports Third Fiscal Quarter Financial Results 4China Medical Technologies Reports Third Fiscal Quarter Financial Results 5China Medical Technologies Reports Third Fiscal Quarter Financial Results 6China Medical Technologies Reports Third Fiscal Quarter Financial Results 7China Medical Technologies Reports Third Fiscal Quarter Financial Results 8China Medical Technologies Reports Third Fiscal Quarter Financial Results 9China Medical Technologies Reports Third Fiscal Quarter Financial Results 10China Medical Technologies Reports Third Fiscal Quarter Financial Results 11China Medical Technologies Reports Third Fiscal Quarter Financial Results 12China Medical Technologies Reports Third Fiscal Quarter Financial Results 13China Medical Technologies Reports Third Fiscal Quarter Financial Results 14China Medical Technologies Reports Third Fiscal Quarter Financial Results 15China Medical Technologies Reports Third Fiscal Quarter Financial Results 16China Medical Technologies Reports Third Fiscal Quarter Financial Results 17China Medical Technologies Reports Third Fiscal Quarter Financial Results 18China Medical Technologies Reports Third Fiscal Quarter Financial Results 19China Medical Technologies Reports Third Fiscal Quarter Financial Results 20China Medical Technologies Reports Third Fiscal Quarter Financial Results 21China Medical Technologies Reports Third Fiscal Quarter Financial Results 22New Study Shows Nu-Tek's Modified Potassium Chloride Improves Yields in Meat Processing 2New Study Shows Nu-Tek's Modified Potassium Chloride Improves Yields in Meat Processing 3Medivation to Host Conference Call at 8:30 a.m. Eastern Time Tomorrow to Discuss Phase 3 Trial Results for Dimebon in Alzheimer's Disease 2Medivation to Host Conference Call at 8:30 a.m. Eastern Time Tomorrow to Discuss Phase 3 Trial Results for Dimebon in Alzheimer's Disease 3
Porcine parvovirus and mycoplasma tested. Contains 0.5 g/L of trypsin (1:250) and 0.2 g/L of EDTA4Na in Hanks' Balanced Salt Solution without CaCl2 MgCl2 6H2O and MgSO4 7H2O. Contains phenol red....
Immunogen: Recombinant full length protein. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Immunogen: Synthetic peptide: R(89) L A F T V D D N P T K P T T R Q R Y(107) Storage: -20 C, Avoid Freeze/Thaw Cycles...
...
Biology Products: