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Beckman Foundation Announces Funding for Light-Sheet Microscopy and Data Science

The Arnold and Mabel Beckman Foundation today announced an open call for proposals from nonprofit U.S. universities and research institutions for its Instrumentation Grant for Advanced Light-Sheet Microscopy and Data Science. The grant will provide support of up to $1.2 million per site for the acquisition of instrumentation, development and maintenance; support for data science collaborations within research teams; and costs for proposed research programs. Investing in this instrumentation underscores the Foundation’s mission of supporting research breakthroughs in chemistry and the life sciences.

Light-sheet microscopy, recognized with the 2014 Nobel Prize in Chemistry to Betzig, Hell and Moerner, uses a plane of light to perpendicularly illuminate a cross-section of a sample, permitting the user to rapidly produce high-resolution images while imposing less stress and damage on the sample than with conventional light microscopy. The Foundation is eager to expand access to the dynamic, 3D, and long-term imaging capabilities offered by light-sheet microscope modalities such as super-resolution light-sheet, lattice light-sheet, Airy beam light-sheet, single-optic light-sheet, and multi-photon imaging in order to tackle new biological questions enabled by these advanced imaging techniques.

“The Beckman Foundation has identified advanced light-sheet microscopy as an exciting new technology area that has the potential to help answer many challenging research questions. This grant has two aims: To provide access to this cutting-edge technology, and also to incorporate the data science experts in the core program teams for innovations in data analysis techniques and sharing results with the broader research community,” explained Dr. Anne Hultgren, Beckman Foundation’s Executive Director. “In 2017 we introduced a similar grant that brought Cryo-EM technology to several institutions, and we are excited to make a new instrumentation investment that will increase access to the field of light-sheet microscopy.”

Proposal details and instructions are available on the Arnold and Mabel Beckman Foundation application submission portal. Questions regarding eligibility can be directed to Dr. Anne Hultgren at Program awards are tentatively scheduled to be funded by May 2021.

About the Arnold and Mabel Beckman Foundation
Located in Irvine, California, the Arnold and Mabel Beckman Foundation supports researchers and nonprofit research institutions in making the next generation of breakthroughs in chemistry and the life sciences. Founded in 1977 by 20th century scientific instrumentation pioneer Dr. Arnold O. Beckman, the Foundation supports institutions and young scientists whose creative, high-risk, and interdisciplinary research will lead to innovations and new tools and methods for scientific discovery. For more information, visit

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