Navigation Links
Baculovirus-recognizing human cell receptor identified for the first time
Date:9/27/2013

The receptor used by baculovirus to enter and interact with human cells has been identified. This syndecan-1 receptor was identified for the first time in a recent collaborative study carried out by the University of Eastern Finland and the University of Jyvskyl in Finland. The findings increase our understanding of the strategies by which the virus causes infection in cells and further facilitates the development of baculovirus for applications of gene transfer. According to the researchers, the identification of the syndecan-1 receptor helps in understanding the ways baculovirus interacts with human cells and sheds further light on the mechanisms the virus uses in human cells.

The study also focused on the role of the syndecan-1 receptor in the cell penetration of baculovirus.

The study was published in the prestigious Journal of Virology. The article was featured in the Spotlight section of the journal, which is reserved for especially interesting and distinguished publications.

Used in drugs and vaccines

Baculovirus is an insect-infecting virus, which is largely utilised in biotechnology applications. Baculoviruses are used, for example, in the manufacturing of Glybera, the first gene therapy of the Western world, and in the manufacturing of the cancer vaccines Cervarix and Provenge, and the influenza vaccine Flublok. The technology is approved by the U.S. Food and Drug Administration, FDA, and the European Medicines Agency, EMA.

Baculovirus is not harmful to human cells, and this is why baculoviruses have become subjects of intensive research also with regard to gene therapy. In gene therapy, DNA to correct genetic errors is transported into cells using a variety of methods. Earlier studies have not been able to identify the receptor that recognises the virus, despite the fact that baculovirus has been studied intensively for decades.


'/>"/>

Contact: Kari Airenne
kari.airenne@uef.fi
358-403-553-131
University of Eastern Finland
Source:Eurekalert

Page: 1

Related biology news :

1. Nearby chimpanzee populations show much greater genetic diversity than distant human populations
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
4. A birds song may teach us about human speech disorders
5. Scientists produce eye structures from human blood-derived stem cells
6. Human noise has ripple effects on plants
7. Did climate change shape human evolution?
8. Harmless human virus may be able to boost the effects of chemotherapy
9. Study resolves debate on human cell shut-down process
10. Fine-scale analysis of the human brain yields insight into its distinctive composition
11. Bartonella infection associated with rheumatoid illnesses in humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... Melbourne researchers have challenged conventional thinking on how the ... new mechanism for how bowel cancer starts. , The ... maintaining and regenerating the ,crypts, that are a feature ... are involved in bowel cancer development, a controversial finding ... existence. , Using 3D imaging technologies, Dr Chin Wee ...
(Date:10/16/2014)... causes severe respiratory tract infections and worldwide claims ... at VIB and Ghent University have succeeded in ... common virus infection. , Xavier Saelens (VIB/UGent): ... the way for the development of a novel ... causes suffering in numerous small children and elderly ...
(Date:10/16/2014)... Conn. , October 16, 2014 NXT-ID, ... or the "Company"), a biometric authentication company focused on ... its leading edge technologies including Wocket™, the Smart Wallet, ... (FiRe) Conferenece. FiRe is a leading global conference on ... Hosted by Mark Anderson , founder and ...
Breaking Biology News(10 mins):Cryptic clues drive new theory of bowel cancer development 2New perspectives for development of an RSV vaccine 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3
... Sanctuary have collected the first camera trap video footage ... individuals remaining, Cross River gorillas are the world,s rarest ... by field researchers. Collected from one of four ... protected area, the footage reveals eight Cross River gorillas ...
... CUNY Energy Institute, which has been developing innovative low-cost ... discharge rates and high energy densities, announced that it ... The Institute said large-scale commercialization of the battery would ... an environmentally friendlier and less costly alternative to nickel ...
... to develop more efficient biofuel cells, seen as the future ... biological materials, they have the potential to be used indefinitely ... possible to replace a battery or recharge them. , Most ... the Leeds research will focus on bacterial enzymes that can ...
Cached Biology News:Camera trap video offers rare glimpse of world's rarest gorilla 2CUNY Energy Institute battery system could reduce buildings' electric bills 2Creating energy from light and air - new research on biofuel cells 2
(Date:10/20/2014)... Convey Computer , the leader ... Iowa State University won first place in the ... HC-2ex, the team’s solution achieved the highest overall performance ... second place finisher. , Experts from all segments of ... long challenge, using a variety of design tools, hardware ...
(Date:10/20/2014)... BOSTON , Oct. 20, 2014 ... commercialization company tackling big healthcare problems, announced today ... investment round, with participation from Invesco Perpetual, a ... be used to drive PureTech,s existing pipeline forward ... technologies. "PureTech has the scientific creativity to really ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 ... Industry Meeting (ABIM). ABIM will take ... More information about ABIM 2014 is now ... , Delegates representing companies and organizations from ... and obtain information on the latest products ...
(Date:10/19/2014)... The report "Chocolate, Cocoa Beans, Lecithin, ... Geography Trend and Forecast (2011 - 2016)," analyzes ... and studies the major market drivers, restraints, and opportunities ... Asia. , The global chocolate market is expected to ... 2016 at an estimated CAGR of 2.7% from 2011 ...
Breaking Biology Technology:Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 2Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 4
... New DNA-Based Test Produces Decisive Result Within ... Enigma Diagnostics,the life sciences company developing ... it has successfully completed a project,commissioned by ... to,develop a rapid, point-of-care diagnostic system for ...
... Agreement in Principle with U.S. Attorney,s Office; ... Earnings Exceed Company Guidance;,Company Again ... Pa., Nov. 8 Cephalon, Inc. (Nasdaq:,CEPH) today reported third ... $457.2 million for the third quarter of 2006 and,within the ...
... ExonHit Therapeutics, a,drug and diagnostic discovery company, has ... test. The company expects to have,this test certified ... its GLP (Good,Laboratory Practices) compliant laboratories to the ... ExonHit test aims to identify patients suffering from,Alzheimer,s ...
Cached Biology Technology:Enigma Diagnostics to Develop Clinical Diagnostics Platform for UK National Chlamydia Screening Programme 2Enigma Diagnostics to Develop Clinical Diagnostics Platform for UK National Chlamydia Screening Programme 3Cephalon Announces Strong Third Quarter Financial Results 2Cephalon Announces Strong Third Quarter Financial Results 3Cephalon Announces Strong Third Quarter Financial Results 4Cephalon Announces Strong Third Quarter Financial Results 5Cephalon Announces Strong Third Quarter Financial Results 6Cephalon Announces Strong Third Quarter Financial Results 7Cephalon Announces Strong Third Quarter Financial Results 8Cephalon Announces Strong Third Quarter Financial Results 9Cephalon Announces Strong Third Quarter Financial Results 10Cephalon Announces Strong Third Quarter Financial Results 11Cephalon Announces Strong Third Quarter Financial Results 12Cephalon Announces Strong Third Quarter Financial Results 13Cephalon Announces Strong Third Quarter Financial Results 14Cephalon Announces Strong Third Quarter Financial Results 15Cephalon Announces Strong Third Quarter Financial Results 16Cephalon Announces Strong Third Quarter Financial Results 17Cephalon Announces Strong Third Quarter Financial Results 18ExonHit Completes a Prototype to Detect Alzheimer's Disease From Blood 2ExonHit Completes a Prototype to Detect Alzheimer's Disease From Blood 3ExonHit Completes a Prototype to Detect Alzheimer's Disease From Blood 4
Cytofix Buffer 100 mls...
Rabbit polyclonal to JAK1 (phospho Y1022 + Y1023) ( Abpromise for all tested applications). entrezGeneID: 3716 SwissProtID: P23458...
Perm/Wash Buffer 250 Tests...
PCR purification kit, 100 preps...
Biology Products: