Navigation Links
Baculovirus-recognizing human cell receptor identified for the first time
Date:9/27/2013

The receptor used by baculovirus to enter and interact with human cells has been identified. This syndecan-1 receptor was identified for the first time in a recent collaborative study carried out by the University of Eastern Finland and the University of Jyvskyl in Finland. The findings increase our understanding of the strategies by which the virus causes infection in cells and further facilitates the development of baculovirus for applications of gene transfer. According to the researchers, the identification of the syndecan-1 receptor helps in understanding the ways baculovirus interacts with human cells and sheds further light on the mechanisms the virus uses in human cells.

The study also focused on the role of the syndecan-1 receptor in the cell penetration of baculovirus.

The study was published in the prestigious Journal of Virology. The article was featured in the Spotlight section of the journal, which is reserved for especially interesting and distinguished publications.

Used in drugs and vaccines

Baculovirus is an insect-infecting virus, which is largely utilised in biotechnology applications. Baculoviruses are used, for example, in the manufacturing of Glybera, the first gene therapy of the Western world, and in the manufacturing of the cancer vaccines Cervarix and Provenge, and the influenza vaccine Flublok. The technology is approved by the U.S. Food and Drug Administration, FDA, and the European Medicines Agency, EMA.

Baculovirus is not harmful to human cells, and this is why baculoviruses have become subjects of intensive research also with regard to gene therapy. In gene therapy, DNA to correct genetic errors is transported into cells using a variety of methods. Earlier studies have not been able to identify the receptor that recognises the virus, despite the fact that baculovirus has been studied intensively for decades.


'/>"/>

Contact: Kari Airenne
kari.airenne@uef.fi
358-403-553-131
University of Eastern Finland
Source:Eurekalert

Page: 1

Related biology news :

1. Nearby chimpanzee populations show much greater genetic diversity than distant human populations
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
4. A birds song may teach us about human speech disorders
5. Scientists produce eye structures from human blood-derived stem cells
6. Human noise has ripple effects on plants
7. Did climate change shape human evolution?
8. Harmless human virus may be able to boost the effects of chemotherapy
9. Study resolves debate on human cell shut-down process
10. Fine-scale analysis of the human brain yields insight into its distinctive composition
11. Bartonella infection associated with rheumatoid illnesses in humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/10/2015)... 2015 Research and Markets ( ... "Security Competitive Profiles - NEC" report to their ... NEC will continue to supply a range of IT ... a company focus on the development of a Big ... opportunities in the Asia-Pacific region ...
(Date:4/6/2015)... Apr. 6, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce ... patent 62/143028 for MINIATURE, MULTI-PURPOSE ANTENNA ... NXT-ID introduces a new revolutionary method ... surrounds the use of miniature antenna modules for ...
(Date:4/2/2015)... 2, 2015 According to preliminary ... to somewhat higher than 125 MSEK. This exceeds the ... 2014 that revenues for Q1 2015 would be in ... for Q4 2014. The operating result for the first ... complete interim report will as previously communicated be published ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4Fingerprint Cards Revises Revenues for Q1 2015 2
... Questions about the existence of life in outer space may ... Houston professor. , Understanding how life evolved on Earth is ... universe one might find life and what it might be ... and biochemistry. Fox is finishing work on a three-year research ...
... of one family of antibiotics kill bacteria that make ... developers make slight changes to these antibiotics to make ... Irina Artsimovitch, a study co-author and an assistant professor ... studied belong to the rifamycin family. Until now, researchers ...
... to seven million years ago, when the lineage of ... rutabagas and turnips may have been one of the ... the University of Minnesota and Richard Wrangham of Harvard ... roots and tubers must have sustained our ancestors who ...
Cached Biology News:Evolution of life on Earth may hold key to finding life in outer space 2Evolution of life on Earth may hold key to finding life in outer space 3Researchers find how some antibiotics kill bacteria 2Researchers find how some antibiotics kill bacteria 3“Hitchhiking?Viruses as Cancer Drug Delivery System 2
(Date:5/20/2015)... May 20, 2015  Resolution Bioscience announced today the ... ALK TM , a blood-based liquid biopsy for an ... carcinoma (NSCLC), the most common form of this cancer. ... guide patients to personalized therapies and direct them into ... The Department of Health, the CLIA authority in ...
(Date:5/20/2015)... TRIANGLE PARK, North Carolina , ... weltweit führende Unternehmen für klinische Logistik ... Finanzergebnisse für das Geschäftsjahr 2014, das ... und eingereicht. Das Unternehmen hat die ... Logo - http://photos.prnewswire.com/prnh/20110930/NY78064LOGO ...
(Date:5/20/2015)... The Greater Gift Initiative, Inc ., (GGI) ... announce they are donating 10,010 vaccines today in recognition ... effort and commitment of clinical trial volunteers who participated ... 2014. , With a mission to advance global ... participation, GGI supports International Clinical Trials Day and how ...
(Date:5/20/2015)... , May 20, 2015  OncoSec Medical ... intratumoral cancer immunotherapies, will present data from ongoing ... Academy of Sciences, Emerging Approaches to Cancer Immunotherapy. ... , MD, and Chief Medical Officer Mai. H. ... Expression of Plasmid IL-12 Can Increase CD8 TILs ...
Breaking Biology Technology:Resolution Bioscience Receives CLIA Certification for its Diagnostic Laboratory and Launches CLIA-Certified Liquid Biopsy for Lung Cancer 2Marken schließt Ergebnisse für das Geschäftsjahr 2014 ab 2The Greater Gift Initiative Donates over 10,000 Vaccines in Honor of International Clinical Trials Day 2OncoSec Medical to Present Data at the New York Academy of Sciences' Cancer Immunotherapy Symposium 2OncoSec Medical to Present Data at the New York Academy of Sciences' Cancer Immunotherapy Symposium 3OncoSec Medical to Present Data at the New York Academy of Sciences' Cancer Immunotherapy Symposium 4
... Cell Therapy From Cellonis Biotechnologies Can Help Children With Diabetes Get Back... -- BEIJING, Aug. 24 ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... ""; BitlyCB.alertResponse = function(data) { var s = ,; var first_result; // Results are keyed by ...
... and BEDMINSTER, N.J., Aug. 23 Archimedes ... pain, neurology and critical care sectors, announced today the ... Jersey. Archimedes has offices in a number ... in Europe.  The opening of its US office marks ...
... Bjerke Appointed as new CEO for Karolinska Development -- STOCKHOLM, August 23, 2010 ... ... ... first_result; // Results are keyed by longUrl, so we need to grab the first one. for (var ...
Cached Biology Technology:Novel Stem Cell Therapy From Cellonis Biotechnologies Can Help Children With Diabetes Get Back Their Normal Lives 2Novel Stem Cell Therapy From Cellonis Biotechnologies Can Help Children With Diabetes Get Back Their Normal Lives 3Novel Stem Cell Therapy From Cellonis Biotechnologies Can Help Children With Diabetes Get Back Their Normal Lives 4Novel Stem Cell Therapy From Cellonis Biotechnologies Can Help Children With Diabetes Get Back Their Normal Lives 5Novel Stem Cell Therapy From Cellonis Biotechnologies Can Help Children With Diabetes Get Back Their Normal Lives 6Archimedes Pharma US Announces New US Headquarters In Bedminster, New Jersey 2Archimedes Pharma US Announces New US Headquarters In Bedminster, New Jersey 3Archimedes Pharma US Announces New US Headquarters In Bedminster, New Jersey 4Torbjorn Bjerke Appointed as new CEO for Karolinska Development 2Torbjorn Bjerke Appointed as new CEO for Karolinska Development 3Torbjorn Bjerke Appointed as new CEO for Karolinska Development 4Torbjorn Bjerke Appointed as new CEO for Karolinska Development 5Torbjorn Bjerke Appointed as new CEO for Karolinska Development 6
Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....
Experion StdSens chips are the microfluidic chips used to perform standard-sensitivity RNA analysis (nanogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to...
...
Experion HighSens chips are the microfluidic chips used to perform high-sensitivity RNA analysis (picogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to ru...
Biology Products: