Navigation Links
Baculovirus-recognizing human cell receptor identified for the first time
Date:9/27/2013

The receptor used by baculovirus to enter and interact with human cells has been identified. This syndecan-1 receptor was identified for the first time in a recent collaborative study carried out by the University of Eastern Finland and the University of Jyvskyl in Finland. The findings increase our understanding of the strategies by which the virus causes infection in cells and further facilitates the development of baculovirus for applications of gene transfer. According to the researchers, the identification of the syndecan-1 receptor helps in understanding the ways baculovirus interacts with human cells and sheds further light on the mechanisms the virus uses in human cells.

The study also focused on the role of the syndecan-1 receptor in the cell penetration of baculovirus.

The study was published in the prestigious Journal of Virology. The article was featured in the Spotlight section of the journal, which is reserved for especially interesting and distinguished publications.

Used in drugs and vaccines

Baculovirus is an insect-infecting virus, which is largely utilised in biotechnology applications. Baculoviruses are used, for example, in the manufacturing of Glybera, the first gene therapy of the Western world, and in the manufacturing of the cancer vaccines Cervarix and Provenge, and the influenza vaccine Flublok. The technology is approved by the U.S. Food and Drug Administration, FDA, and the European Medicines Agency, EMA.

Baculovirus is not harmful to human cells, and this is why baculoviruses have become subjects of intensive research also with regard to gene therapy. In gene therapy, DNA to correct genetic errors is transported into cells using a variety of methods. Earlier studies have not been able to identify the receptor that recognises the virus, despite the fact that baculovirus has been studied intensively for decades.


'/>"/>

Contact: Kari Airenne
kari.airenne@uef.fi
358-403-553-131
University of Eastern Finland
Source:Eurekalert

Page: 1

Related biology news :

1. Nearby chimpanzee populations show much greater genetic diversity than distant human populations
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
4. A birds song may teach us about human speech disorders
5. Scientists produce eye structures from human blood-derived stem cells
6. Human noise has ripple effects on plants
7. Did climate change shape human evolution?
8. Harmless human virus may be able to boost the effects of chemotherapy
9. Study resolves debate on human cell shut-down process
10. Fine-scale analysis of the human brain yields insight into its distinctive composition
11. Bartonella infection associated with rheumatoid illnesses in humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... of Toronto Scarborough research shows that male black widow ... a rare example of mate preference by male ... post-doc Emily MacLeod and Maydianne Andrade, a professor in ... field studies and the wild that males overwhelmingly chose ... male black widows can tell whether a potential mate ...
(Date:4/23/2014)... TX (4/23/14) -- Researchers have found evidence of ... factors that increase aggressive behavior in children, especially ... not all children exposed to prenatal smoking will ... will not," said Brian Boutwell, Assistant Professor at ... and senior author on the study. "One ...
(Date:4/23/2014)... today announced Sophie Martin of the University of Lausanne, ... Medal. The award acknowledges her work to understand the ... the cell. , Martin has been working for the ... the way in which the spatial organization of cells ... last 11 years, she has been using fission yeast, ...
Breaking Biology News(10 mins):Picky male black widow spiders prefer well-fed virgins 2Genetics risk, prenatal smoking may predict behavioral problems 2EMBO Gold Medal 2014 awarded to Sophie Martin 2
... October 29, 2007 The average price for all ... gallon nationwide, but the pain at the pump might ... may eliminate one of the biggest hurdles to the ... assistant professor of chemical and biomolecular engineering, led the ...
... University have developed a cancer fighting technology which uses ... tumours. Therapeutic antibodies have long been recognised ... target tumour cells has proved to be very difficult. ... Thompson from Newcastle University have developed a procedure to ...
... Institution of Oceanography at UC San Diego, that allows ... world oceans simultaneously is approaching its coverage goal after ... profiling floats measures ocean water temperature, salinity and velocity ... Committee, the international panel of scientists that manage the ...
Cached Biology News:Fuel cells gearing up to power auto industry 2Fuel cells gearing up to power auto industry 3UV light improving chances of fighting cancer 2Unprecedented global measurement network achieves full coverage of oceans 2Unprecedented global measurement network achieves full coverage of oceans 3
(Date:1/15/2014)... Two champions of science, technology, engineering, and ... annual competition for middle and high school students designed ... study. The competition presents students with real-world problems experienced ... Mathematics, and Sciences is a program administered by ...
(Date:1/15/2014)... AudioNotch is the internet's leading provider of Notched Sound ... Patients listen to sound therapy that is tailor-made for ... to months, their tinnitus volume decreases. , AudioNotch has previously ... Notched White Noise. Now, AudioNotch is pleased to announce to ...
(Date:1/14/2014)... 2014  3D Communications, a leading provider of strategic communications services to ... events in the United States and ... Cox , JD, is returning to the firm,s Washington, ... 3D after more than two years of service as Associate Commissioner ...
(Date:1/14/2014)... MA (PRWEB) January 14, 2014 iLab Solutions, ... Detwiler as the new Director of Product Strategy. In this ... well as iLab sub-teams to guide in the development of ... iLab provides the maximum possible benefit to the scientific community ...
Breaking Biology Technology:Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Former FDA Associate Commissioner Returns To 3D Communications 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... Net 2004 in Lille, France. This four-year-old conference ... the transformative power of technology. As the lead speaker ... Economic and Social Conditions, I was eager, frankly, to ... order to hear from and debate my fellow panelists. ...
... Inc., through its non-profit arm the SBC Foundation, has ... Business Journal of Milwaukee has reported. , ... and underserved populations received money to help them use ... Excelerator program , which typically gives from $2,500 to ...
... While the Madison chapter of the World Future Society ... and technological developments, Scott Converse showed them how looking to ... see where the next big thing is coming from. , ... Business and founder of the Web integration firm Cant Dance ...
Cached Biology Technology:Achieving digital solidarity 2Achieving digital solidarity 3Achieving digital solidarity 4Business-school IT director points to reasons for wireless trend 2
Conjugation services for Antibodies, Proteins, Oligos, Peptides, Beads, bioconjugation, antibody-oligonucleotide, LNA peptide, LNA protein, LNA antibody, HRP, Alkaline phosphatase, phycoerythrin, FIT...
SCP-1 (P-17)...
Immunogen: Purified native p24 from strain IIIB. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biotin d anti-mouse Tim-1...
Biology Products: