Navigation Links
BPA + chlorine = bad news
Date:7/17/2013

For years, scientists have been worried about bisphenol A. The chemical is known as an "endocrine disruptor," a substance that interferes with the body's hormone signaling system, and it's found in everything from plastic drink bottles to the linings of food and drink cans to the thermal paper used for cash register receipts not to mention the urine of 92.6 percent of Americans over the age of six. BPA has been associated with the development of chronic diseases such as diabetes, asthma and ovarian dysfunction. In 2012, the FDA banned BPA from use in the production of baby bottles and drinking cups.

BPA's ubiquity in the environment led researchers to ask what it might be doing in publicly supplied drinking water, which is contaminated at its source by BPA-laden discarded plastic and later picks up more of the chemical when it passes through PVC plastic pipes. Most public water supplies are chlorinated to kill bacteria, and the BPA in the water also becomes chlorinated, acquiring one or more chlorine atoms from the water around it. The question was, how does this chlorinated BPA behave in the body?

The answer, generated from cell-culture experiments, was that it produced different but no less profound effects. "We found that when you modify the BPA it works just as dramatically but in different ways on the same systems," said University of Texas Medical Branch at Galveston professor Cheryl Watson, senior author of a paper on the study now online in Endocrine Disruptors.

Watson and graduate student Ren Vias examined both chlorinated BPA and BPA that had undergone sulfonation and glucuronodation two processes the body uses to make a compound easier to excrete. In all three cases the modified forms of BPA worked through membrane estrogen receptors to deactivate key signaling enzymes known as ERK and JNK kinases.

"These kinases are major control centers, gathering all the cell signals, making decisions and then expedit
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2

Related biology news :

1. UofL scientist uncovers how airway cells regenerate after chlorine gas injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2015)... Feb. 9, 2015  Lintec of America recently announced ... carbon nanotube (CNT) macrostructures, including sheets, yarns and ribbons, ... Leveraging the vast industrial resources of the ... , Lintec of America is forming the Nano-Science ... , focusing on scaling up the manufacturing and ...
(Date:2/5/2015)... 5, 2015  Marken is starting its 35 th ... launched a new marketing campaign to solidify its place ... new campaign focuses on First as a ... The first headline in the series, ... with its client,s priorities. Marken recognizes the need to ...
(Date:2/5/2015)... NXT-ID, Inc. (NASDAQ: NXTD and ... focused on the growing mobile commerce market, announces the ... as part of its 2015 marketing and branding initiatives ... new consumer website for Wocketwallet.com earlier this month. ... said, "Our new corporate website naturally showcases our premiere ...
Breaking Biology News(10 mins):Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 2Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 3Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 4Marken Launches New Patient-Centric Campaign 2NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 2NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 3
... trials for a vaccine against Streptococcus A, the germ that ... heart is just one of the possible long term consequences ... had heart surgery to repair damage suffered from rheumatic fever ... Good, Principal Research Leader at the Institute for Glycomics has ...
... Bethesda, MDWomen who are pregnant or using synthetic progesterone ... infections including malaria, Listeria, HIV, and herpes simplex virus. ... issue of the Journal of Leukocyte Biology ... the progesterone receptor, a pregnancy hormone sensor, targets a ...
... Researchers at Wake Forest Baptist Medical Center and ... cells in bone marrow that have the natural ability ... suggesting their potential to restore healthy tissue in patients ... million Americans have IBD, which is characterized by frequent ...
Cached Biology News:Progesterone may be why pregnant women are more vulnerable to certain infections 2Research supports promise of cell therapy for bowel disease 2
(Date:2/26/2015)... (PRWEB) February 26, 2015 The ... -12, at the Ernest N. Morial Convention Center ... (count as of February 19, 2015) displaying products ... industrial, academic, and government labs. The Exposition will ... but not limited to, analytical chemistry; drug discovery; ...
(Date:2/26/2015)... JUPITER, Fla. , Feb. 26, 2015 /PRNewswire/ ... biotechnology company whose patented and proprietary technologies are ... other proteins for the bioenergy, bio-based chemical, biopharmaceutical ... will report its financial results for year ending ... March 11, 2015 and will host a conference ...
(Date:2/26/2015)... 26, 2015   Lexicon Pharmaceuticals, Inc. (Nasdaq: ... at the Cowen 35 th Annual Health Care Conference ... Boston .  Lexicon management will provide an ... A webcast of the presentation will be available through Lexicon,s ... presentation will be available at www.lexpharma.com until April ...
(Date:2/26/2015)... LONDON , February 26, 2015 ... of subjects into PEACH, the first pivotal trial ... dialysis dependent chronic kidney disease (DD-CKD), has completed ... achieved. PT20, invented by leading UK-based ... licensed by Phosphate Therapeutics, is a novel phosphate ...
Breaking Biology Technology:Pittcon 2015 Announces Exposition Highlights 2Dyadic International To Announce Fourth Quarter 2014 Financial Results And Host Conference Call On Wednesday, March 11, 2015 2Dyadic International To Announce Fourth Quarter 2014 Financial Results And Host Conference Call On Wednesday, March 11, 2015 3Lexicon To Present At The Cowen 35th Annual Health Care Conference 2Phosphate Therapeutics Announces Completion of Subject Recruitment Into the PEACH Pivotal Phase 2 Study of its Novel Phosphate Binder (PT20) for the Treatment of Hyperphosphataemia 2Phosphate Therapeutics Announces Completion of Subject Recruitment Into the PEACH Pivotal Phase 2 Study of its Novel Phosphate Binder (PT20) for the Treatment of Hyperphosphataemia 3
... announced on Tuesday that they have signed an agreement ... system CardioIMS. The system will be implemented in the ... needs of children and adults with hereditary heart defects. ... of the Center's administrative and clinical needs, looking specifically ...
... computer science department The Internet may have become ... seminar Tuesday evening held by the University of Wisconsin-Madison's ... commercial Internet is no longer friendly to experimentation. , ... department, directs PlanetLab , a distributed network of ...
... University of Wisconsin-Madison will lead 21 state colleges in ... in science, technology, engineering and math, the university has ... four-year universities and two-year colleges from around the state. ... program of the National Science Foundation, contributed a $2.5 ...
Cached Biology Technology:Children's Hospital chooses Camtronics for cardiology IT system 2UW attracts speaker on network that could supplant Internet 2UW attracts speaker on network that could supplant Internet 3UW attracts speaker on network that could supplant Internet 4
DTT, 25g...
... Agarose overlays are commonly ... Many commercial "DNA grade" agaroses ... toxic to insect cells or ... to obtain good overlays. Novagen's ...
Antibody specific for trimethyl-Lys27 of histone H3. Mouse monoclonal. Antigen: Synthetic peptide derived from histone H3, trimethylated at lysine 27...
...
Biology Products: