Navigation Links
Artificial platelets could treat injured soldiers on the battlefield
Date:2/15/2013

to Ashley Brown, a postdoctoral fellow working on the project.

After an injury, the most critical need is to stop the bleeding. But as traumatic injuries heal, they often produce significant scarring that is difficult to treat. Georgia Tech researchers are working on both sides of the problem, developing cell signaling techniques that may head off the formation of scars as well as techniques for addressing the fibrosis that is often the long-term result. Beyond helping halt the bleeding, the synthetic platelets would deliver regulatory chemicals designed to prevent scarring.

"The blood clot actually ends up directing how the entire wound healing process is going to occur," Barker said. "The initial clot matrix instructs very specific cellular behaviors which have consequences for the next wave of cells that comes in to do specific jobs, which have consequences for the next wave of cells. If we can modify that initial clot, it can become the three-dimensional matrix needed to build the regenerated or repaired tissue."

The synthetic platelets, made from tiny structures known as hydrogels, could be injected into the bloodstream where they would circulate until activated by the body's own clotting processes. Once activated, the particles which are about one micron in diameter would change shape, converting to a thin film that would help seal wounds. To develop these hydrogels, Barker is collaborating with Andrew Lyon, a professor in Georgia Tech's School of Chemistry and Biochemistry.

The bloodstream contains proteins known as fibrinogen that are the precursors for fibrin, the polymer that provides the basic structure for natural blood clots. When they receive the right signals from a protein called thrombin, these precursors polymerize at the site of the bleeding. To prevent unintended activation of their synthetic platelets, the researchers use the same trigger.

The researchers followed a process known as molecular ev
'/>"/>

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Artificial retina receives FDA approval
2. Artificial atoms allow for magnetic resonance on individual cells
3. Nanomaterials key to developing stronger artificial hearts
4. U. of Minn. researchers unveil first artificial enzyme created by evolution in a test tube
5. Cornell engineers solve a biological mystery and boost artificial intelligence
6. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
7. New geometries: Researchers create new shapes of artificial microcompartments
8. High-speed video and artificial flowers shed light on mysteries of hummingbird-pollinated flowers
9. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
10. Artificial intelligence helps detect subtle differences in mutant worms
11. UD partner in NIH research project to produce artificial salivary glands
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Artificial platelets could treat injured soldiers on the battlefield
(Date:10/16/2014)... -- NXT-ID, Inc. (NASDAQ: NXTD and ... focused on the growing mobile commerce market announces that ... Smart Wallet, at the 13 th annual Future ... conference on the intersection of technology and the economy. ... founder and publisher of the Strategic News Service™, the ...
(Date:10/15/2014)... The book ,Models of Life, is a non-traditional biophysics ... itself. The book is a journey of discovery into ... of life and biological regulation. It is about how ... strategic communication between the billions of cells in an ... the relationships between principles, which can be found on ...
(Date:10/15/2014)... have linked increased resistance to bacterial pneumonia in female ... hormone estrogen. , Females are naturally more resistant to ... scientists has shown that increased resistance to bacterial pneumonia ... oxide synthase 3 (NOS3). They also show that this ... female sex hormone estrogen. , The team, lead by ...
Breaking Biology News(10 mins):NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3New book about life as seen from physics 2
... Canadell, from the Global Carbon Project and CSIRO Marine and ... deforestation releases 1.5 billion tonnes of carbon each year into ... nearly 20 per cent of carbon emissions due to human ... to 130 billion tonnes of carbon by 2100, which is ...
... you’re grazing normally on algae in the rocky intertidal zone ... infected by a parasite. But the better news is, according ... you might have more to eat if plenty of your ... Proceedings of the National Academy of Sciences Early Edition ( ...
... rapid genetic adaptations in the nematode Acrobeloides nanus. ... lay more eggs under polluted conditions than the ... demonstrated this in her study into the long-term ... , Environmental pollution is an important cause of ...
Cached Biology News:Confirmed -- deforestation plays critical climate change role 2Parasites' impact goes beyond host to affect ecosystem 2Parasites' impact goes beyond host to affect ecosystem 3Asexual worm quickly adapts to soil contamination 2
(Date:10/19/2014)... 2014 The Asia-Pacific Bromine Market ... Asia-Pacific with analysis and forecast of revenue. , ... Bromine Market report, to get an idea of ... glimpse of the segmentation in the Asia-Pacific bromine ... figures. , http://www.micromarketmonitor.com/market/asia-pacific-bromine-6741503144.html , Bromine ...
(Date:10/19/2014)... The Asia-Pacific Speech Analytics market report defines ... analysis and forecast of revenue. This market is estimated ... million by 2019, at a Compound Annual Growth Rate ... through the TOC of the Asia-Pacific Speech Analytics market ... provided. It also provides a glimpse of the segmentation ...
(Date:10/19/2014)... The Asian Orthopedic braces and support systems report defines and ... of revenue. The Orthopedic braces and support systems market in ... 2018, at a developing CAGR of 4.4% from 2013 to ... braces and support systems market, to get an idea of ... the segmentation of orthopedic braces and support systems market in ...
(Date:10/19/2014)... 2014 According to market research ... WLAN Controllers; Wireless gateways)]- Global Advancements, Forecasts and ... global Outdoor Wi-Fi market with analysis and forecasting ... also identifies the drivers and the restrains for ... opportunities and challenges. , Browse 65 market data ...
Breaking Biology Technology:The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 2The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 4Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 2Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 3Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 4
... up nearly 23% of fund raising goal for Central ... Company,(NYSE: LLY ) President and Chief Executive Officer ... United Way of Central Indiana for,its and other United ... of Lilly employees and retirees across the,United States with ...
... 13 Palatin Technologies,Inc. (Amex: PTN ) will ... Monday, November 17, 2008 before the open of the ... conference call and live audio webcast,hosted by Palatin,s executive ... discuss the results of operations in greater detail and ...
... 13 , - Announce Winners of ... Elsevier, the world,s leading research publisher of ... Institutions announced,today winners of the first annual ... to recognize outstanding young scientists and researchers,in ...
Cached Biology Technology:Lilly Contributes $11.1 Million to United Way Annual Campaign 2Palatin Technologies to Report Fiscal Year 2009 First Quarter Results; Conference Call and Webcast on November 17, 2008 2Elsevier and the Association of Southeast Asian Institutions 2Elsevier and the Association of Southeast Asian Institutions 3Elsevier and the Association of Southeast Asian Institutions 4