Navigation Links
Arizona Sate University scientists take steps to unlock the secrets to the fountain of youth
Date:5/4/2014

ASU scientists, together with collaborators from the Chinese Academy of Sciences in Shanghai, have published today, in Nature Structural and Molecular Biology, a first of its kind atomic level look at the enzyme telomerase that may unlock the secrets to the fountain of youth.

Telomeres and the enzyme telomerase have been in the medical news a lot recently due to their connection with aging and cancer. Telomeres are found at the ends of our chromosomes and are stretches of DNA which protect our genetic data, make it possible for cells to divide, and hold some secrets as to how we age and also how we get cancer.

An analogy can be drawn between telomeres at the end of chromosomes and the plastic tips on shoelaces: the telomeres keep chromosome ends from fraying and sticking to each other, which would destroy or scramble our genetic information.

Each time one of our cells divides its telomeres get shorter. When they get too short, the cell can no longer divide and it becomes inactive or dies. This shortening process is associated with aging, cancer and a higher risk of death. The initial telomere lengths may differ between individuals. Clearly, size matters!

"Telomerase is crucial for telomere maintenance and genome integrity," explains Julian Chen, professor of chemistry and biochemistry at ASU and one of the project's senior authors. "Mutations that disrupt telomerase function have been linked to numerous human diseases that arise from telomere shortening and genome instability."

Chen continues that, "Despite the strong medical applications, the mechanism for telomerase holoenzyme (the most important unit of the telomerase complex) assembly remains poorly understood. We are particularly excited about this research because it provides, for the first time, an atomic level description of the protein-RNA interaction in the vertebrate telomerase complex."


'/>"/>

Contact: Jenny Green
jenny.green@asu.edu
480-965-1430
Arizona State University
Source:Eurekalert  

Page: 1

Related biology news :

1. NIH supporting Arizona State University research to help in fight against kidney disease
2. New scorpion discovery near metropolitan Tucson, Arizona
3. University of Arizona Engineering College pursues water technology innovation cluster
4. California and Arizona amaze with 2 new species of desert poppy
5. Arizona State University professor is elected to the National Academy of Sciences
6. University of Houston study shows BP oil spill hurt marshes, but recovery possible
7. University of Alberta led research may have discovered how memories are encoded in our brains
8. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
9. Marshall University study may lead to new treatments for prostate cancer
10. University leads £6 million EU project to tackle obesity
11. A University of Tennessee professors hypothesis may be game changer for evolutionary theory
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Arizona Sate University scientists take steps to unlock the secrets to the fountain of youth
(Date:5/6/2020)... , ... May 06, 2020 ... ... Brevitest Technologies (Houston, Texas, http://www.brevitest.com ) will become the latest out-of-state ... region of Baltimore’s Inner Harbor. , Brevitest has developed a point-of-care analyzer ...
(Date:5/1/2020)... ... April 30, 2020 , ... InBios International Inc., a leading ... been awarded a contract from the Biomedical Advanced Research and Development Authority (BARDA), ... the U.S. Department of Health and Human Services, to develop the SCoV-2 Detect ...
(Date:4/30/2020)... ... 28, 2020 , ... Ever a responsive and supportive partner ... and critical information to life science organizations as they navigate the ever-changing economic ... “Providing the most up-to-date actionable guidance and information has been a keystone of ...
Breaking Biology News(10 mins):
(Date:4/22/2020)... ... April 20, 2020 , ... ... MA, announced today that Omixon’s founder and chairman Dr. Attila Berces returns as ... product Holotype HLA since 2014 before stepping into the CEO role in 2017. ...
(Date:4/7/2020)... Calif. (PRWEB) , ... April 06, 2020 , ... ... their future children, reached 200,000 SneakPeek Early Gender DNA Tests sold in ... SneakPeek was launched as an ecommerce product, where a mom could order her ...
(Date:4/1/2020)... (PRWEB) , ... March 31, ... ... Biology Systems, B.V. (MBS) has developed a method using its revolutionary NEXTGENPCR ... eight minutes. Combined with smaller reaction volumes, increased samples per run, and ...
(Date:3/27/2020)... , ... March 26, 2020 , ... iFirst Medical Technologies, ... development of COVID-19 nasal swab test. , "COVID-19 poses a grave danger to public ... iFirst. "We at iFirst are compelled to act. Broad-based testing and on-the-spot results promise ...
Breaking Biology Technology: