Navigation Links
Antiepileptic drug use while pregnant impacts early child development
Date:7/17/2013

Children whose mothers took antiepileptic drugs (AEDs) while pregnant are at increased risk of early development issues, according to a new study published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy (ILAE). Results of the study suggest that children exposed to AEDs in the womb were at risk for difficulties with motor development, language skills, social skills, and autistic traits compared to children whose mothers did not take anti-seizure medications.

Medical evidence suggests that epilepsy is fairly common in women of childbearing years, with the use of AEDs during pregnancy ranging from 0.2% to 0.5%. Studies have shown that children whose mothers have epilepsy are at increased risk of birth defects (congenital malformations)mainly thought to be caused by use of older generation AEDs during pregnancy. However, there is less understanding of AED effects on cognition during development, and there is a need for more evidence regarding long-term outcomes of children exposed to anti-seizure medication in utero.

A research team, led by Dr. Gyri Veiby from Haukeland University Hospital in Bergen, Norway, studied children from the Norwegian Mother and Child Cohort Study. From 1999 through 2008, researchers recruited mothers at 13-17 weeks of pregnancy; those mothers subsequently reported motor development, language skills, social skills and autistic traits of their children at 18 months (61,351 children) and 36 months (44,147 children). Risk of adverse outcomes was determined in children according to epilepsy in the mother or father, and with or without AED exposure in the womb.

Results show that 333 children were exposed to AEDs in the womb. At 18 months of age, the children exposed to AEDs in utero had increased risk of abnormal gross motor skills and autistic traits. Analysis of AED-exposed children at 36 months revealed an increase of abnormal scores for gross motor skill
'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Page: 1 2

Related biology news :

1. Eating junk food while pregnant may make your child a junk food addict
2. Libertarian paternalism and school lunches: Guiding healthier behavior while preserving choices
3. Protein filmed while unfolding at atomic resolution
4. Music with dinner: Whales sing during foraging season, not just while breeding
5. Multi-tasking whales sing while feeding, not just breeding
6. New process doubles production of alternative fuel while slashing costs
7. Ultrasound idea: Prototype NIST/CU bioreactor evaluates engineered tissue while creating it
8. Pregnant women with high celiac disease antibodies are at risk for low birth weight babies
9. Study reveals risk factors for blood clots in pregnant and postnatal women
10. Progesterone may be why pregnant women are more vulnerable to certain infections
11. Few pregnant women treated for sexually transmitted infections
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... 4, 2014) — Think about the way our bodies ... neighboring cells know that they are supposed to become ... these tissues find the correct place and alignment? Researchers ... crucial questions. , In a new study, UM researchers ... with their surrounding neighbors, at the head-trunk region. Their ...
(Date:11/4/2014)... A majority of Madagascar,s 101 species of lemurs are ... for the rainforests they call home. A new study ... can have on rainforest tree populations, which raises concerns ... the region,s rich biodiversity. , A large proportion of ... Lemurs in turn disperse the seeds of their ...
(Date:11/3/2014)... Cancer Center study published in this month,s ... describes the activity of a recently discovered communication molecule ... It has been known to limit inflammation and the ... system: IL-37 inhibits the ability of the immune system ... mechanism that underlies IL-37,s effect on the immune system ...
Breaking Biology News(10 mins):The inside story: How the brain and skull stay together 2Gardeners of Madagascar rainforest at risk 2Gardeners of Madagascar rainforest at risk 3PNAS: From HIV to cancer, IL-37 regulates immune system 2
... H5N1, the strain of influenza virus that experts fear ... vaccines remain effective as the virus mutates? Researchers present ... Journal of Infectious Diseases, now available online. , ... coworkers at St. Jude Children's Research Hospital in Memphis, ...
... human immune system for centuries. Now, using real-time imaging ... discovered one of the parasite's sneakiest tricks--using dead liver ... bloodstream after leaving the liver. , Robert Ménard, a ... his postdoctoral fellow, Rogerio Amino, at the Institut Pasteur ...
... have presented the first evidence that the addictive drug ... "crystal," increases production of a docking protein that promotes ... , The investigators found that meth increases expression ... more of the virus to invade the immune system. ...
Cached Biology News:Experimental vaccine protects lab animals against several strains of H5N1 2Movie spies on malaria parasite's sneaky behavior 2Movie spies on malaria parasite's sneaky behavior 3Meth promotes spread of virus in HIV-infected users 2
(Date:11/21/2014)... The report, "Synthetic Biology ... Cloning kits), Technology (Bioinformatics, Nanotechnology, Gene Synthesis, ... Bioremediation) - Global Forecast to 2018", analyses ... opportunities, and challenges. , Browse 99 market ... 185 pages and in-depth TOC of the ...
(Date:11/21/2014)... Los Angeles, CA (PRWEB) November 21, 2014 ... is it that makes Albert Einstein so instantly recognizable? ... South African-born physicist, mathematician, astronomer and author Hilton Ratcliffe ... that they have nothing at all to do with ... ( Muse Harbor Publishing , November 21, 2014), Ratcliffe ...
(Date:11/21/2014)... Polaris Group announced today that the ... 1 trial of ADI-PEG 20 in combination with ... pleural mesothelioma (MPM) and non-squamous non-small cell lung ... ADI-PEG 20, both as monotherapy and in combination ... other indications, including breast cancer, melanomas, ovarian cancer, ...
(Date:11/21/2014)... 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") today ... September 30, 2014.  Biorem,s complete 2014 third quarter financial statements and ... Financial Summary:Three-months ended September 30, , Nine-months ended ... , 2014 , 2013 , 2014 ... 5,281 , 6,715 , 14,476 Gross profit ...
Breaking Biology Technology:Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 2Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 4“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 2“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 3“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 4Polaris Group Announces Treatment of First Patient in Phase 1 Study of ADI-PEG 20 plus Pemetrexed and Cisplatin in Malignant Pleural Mesothelioma And Non-Squamous Non-Small Cell Lung Carcinoma 2Biorem Reports Third Quarter Results 2Biorem Reports Third Quarter Results 3
... for testing the quality of a sperm before it ... conception. , Researchers at the University of Edinburgh, funded ... have created a way of chemically ,fingerprinting, individual sperm ... consider whether the sperm is healthy enough to be ...
... DALIAN, China, Jan. 21 /PRNewswire-Asia-FirstCall/ -- China ... or "the Company"),a China-based company that develops, ... therapeutics exclusively within,China, today announced that it ... unused lots of its rabies vaccines. ...
... CryoLife, Inc. (NYSE: CRY ) , ... it received tissue from its 100,000th individual donor. ... Kansas-based organ and tissue procurement organization.Since 1984, through the ... the organ and tissue procurement organizations, CryoLife has been ...
Cached Biology Technology:New sperm shaker to improve IVF success 2China Bio-Immunity Corporation Initiates Voluntary Recalls of Rabies Vaccines 2China Bio-Immunity Corporation Initiates Voluntary Recalls of Rabies Vaccines 3CryoLife, Inc. Receives Tissue From 100,000th Donor, Marking Industry Milestone 2