Navigation Links
Antiepileptic drug use while pregnant impacts early child development
Date:7/17/2013

Children whose mothers took antiepileptic drugs (AEDs) while pregnant are at increased risk of early development issues, according to a new study published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy (ILAE). Results of the study suggest that children exposed to AEDs in the womb were at risk for difficulties with motor development, language skills, social skills, and autistic traits compared to children whose mothers did not take anti-seizure medications.

Medical evidence suggests that epilepsy is fairly common in women of childbearing years, with the use of AEDs during pregnancy ranging from 0.2% to 0.5%. Studies have shown that children whose mothers have epilepsy are at increased risk of birth defects (congenital malformations)mainly thought to be caused by use of older generation AEDs during pregnancy. However, there is less understanding of AED effects on cognition during development, and there is a need for more evidence regarding long-term outcomes of children exposed to anti-seizure medication in utero.

A research team, led by Dr. Gyri Veiby from Haukeland University Hospital in Bergen, Norway, studied children from the Norwegian Mother and Child Cohort Study. From 1999 through 2008, researchers recruited mothers at 13-17 weeks of pregnancy; those mothers subsequently reported motor development, language skills, social skills and autistic traits of their children at 18 months (61,351 children) and 36 months (44,147 children). Risk of adverse outcomes was determined in children according to epilepsy in the mother or father, and with or without AED exposure in the womb.

Results show that 333 children were exposed to AEDs in the womb. At 18 months of age, the children exposed to AEDs in utero had increased risk of abnormal gross motor skills and autistic traits. Analysis of AED-exposed children at 36 months revealed an increase of abnormal scores for gross motor skill
'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Page: 1 2

Related biology news :

1. Eating junk food while pregnant may make your child a junk food addict
2. Libertarian paternalism and school lunches: Guiding healthier behavior while preserving choices
3. Protein filmed while unfolding at atomic resolution
4. Music with dinner: Whales sing during foraging season, not just while breeding
5. Multi-tasking whales sing while feeding, not just breeding
6. New process doubles production of alternative fuel while slashing costs
7. Ultrasound idea: Prototype NIST/CU bioreactor evaluates engineered tissue while creating it
8. Pregnant women with high celiac disease antibodies are at risk for low birth weight babies
9. Study reveals risk factors for blood clots in pregnant and postnatal women
10. Progesterone may be why pregnant women are more vulnerable to certain infections
11. Few pregnant women treated for sexually transmitted infections
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... a key region in the global oceanic circulation. "On the ... Atlantic water flows to the north into the Arctic Ocean ... sea ice push their way out of the Arctic into ... cools here on its way to the north and sinks ... this manner drives the global band of oceanic currents like ...
(Date:8/21/2014)... study recently published in the journal Carcinogenesis ... new role for the protein adenomatous polyposis coli (APC) ... cancer-related deaths in the U.S. , Lead author Kristi ... and co-leader of the Cancer Biology program at the ... her career trying to understand the various activities of ...
(Date:8/21/2014)... has successfully replicated one of the crucial steps in ... sunlight which could manufacture hydrogen as a fuel. , ... an exciting prospect to use them to create hydrogen, ... Hingorani, from the ARC Centre of Excellence for Translational ... Hydrogen offers potential as a zero-carbon replacement for petroleum ...
Breaking Biology News(10 mins):Arctic sea ice influenced force of the Gulf Stream 2Arctic sea ice influenced force of the Gulf Stream 3Research offers insight into cellular biology of colorectal cancer 2Research offers insight into cellular biology of colorectal cancer 3Water and sunlight the formula for sustainable fuel 2
... papers that have been recently published in Geophysical Research ... Earth ( JGR-B ) and Journal of Geophysical ... 1. An earthquake in Japan caused large waves in Norwegian ... in Ohio, 3. The Arctic is especially sensitive to black ...
... Johns Hopkins have uncovered a protein switch that can ... depending on the signals it detects. Its dual role ... network of signals that shapes our brain,s circuitry, the ... the July 31 issue of the Journal of ...
... A strain of bacteria that causes skin and soft tissue ... study to be published in mBio , the online ... who conducted the genetic analysis of strains of Staphylococcus ... to methicillin after they crossed over into humans around forty ...
Cached Biology News:AGU journal highlights -- Aug. 13, 2013 2AGU journal highlights -- Aug. 13, 2013 3AGU journal highlights -- Aug. 13, 2013 4AGU journal highlights -- Aug. 13, 2013 5AGU journal highlights -- Aug. 13, 2013 6AGU journal highlights -- Aug. 13, 2013 7AGU journal highlights -- Aug. 13, 2013 8Newly discovered 'switch' plays dual role in memory formation 2MRSA strain in humans originally came from cattle 2MRSA strain in humans originally came from cattle 3
(Date:8/22/2014)... Muncie, IN (PRWEB) August 22, 2014 Today ... Review in the United States Court of Appeals for the ... for Model Aircraft published in the Federal Register on June ... Interpretive Rule is contrary to the text and intent of ... 112-95, and violates Congress’ specific prohibition on any new rules ...
(Date:8/22/2014)... published today (August 22nd), in the scientific journal ... Neuroscience Programme establish the effect of serotonin on ... genetic and optical techniques., "Serotonin is a small ... range of brain functions, from the control of ... emotional behaviours, This neurotransmitter is also popularly thought ...
(Date:8/22/2014)... 2014 Ophthalmic drug delivery technologies ... challenging endeavors as the anatomy, physiology and biochemistry ... the foreign substances. Ocular drug delivery technologies provide ... and minimal use of needles; also it enables ... provides specific targeting within the ocular globe. On ...
(Date:8/22/2014)... Research and Markets has announced the addition ... Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - ... The global molecular biology enzymes market was ... to grow at a CAGR of 13.74% to reach ... reagents find applications in a large number of fields ...
Breaking Biology Technology:AMA Files Petition for Review of FAA’s Interpretive Rule 2From happiness to pain: Understanding serotonin's function 2Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 4Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 2Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 3
... ... SCD Probiotics has released a case study that provides ... - with documented evidence of the effectivness of beneficial microbial applications. ... light by the Environmental Protection Agency, who recently agreed to ...
... ... to include one of a kind iron supplement. , ... Las Vegas, NV (PRWEB) June 24, 2010 -- Bariatric Advantage, a ... their new products at the ASMBS conference. The Company located in Booth #115 enjoyed high ...
... 22 As previously announced on October 24th, 2009 delSECUR ... to an Ontario company, QTECH SYSTEMS INC. in exchange for 49% ... appointments to QTECH,s Management Team and the appointment of a new Chief Technology ... , , ...
Cached Biology Technology:Effective Odor and Pathogen Control in Livestock Operations Revealed in New Case Study 2delSECUR CORPORATION Announces Organizational Update as QTECH SYSTEMS INC. Expands Leadership Team 2delSECUR CORPORATION Announces Organizational Update as QTECH SYSTEMS INC. Expands Leadership Team 3
DAPI: 4', 6-Diamino-2-phenylindole dihydrochloride. Antifade Solution: p-Phenylenediamine and glycerol in PBS solution. 0.4g/mL DAPI suspended in Antifade....
Anti-Mouse Qa.m8, Ascites (Clone 5035-24.1) (mouse IgG3)...
... 13(S)-HODE-d4 contains 4 deuterium atoms at the ... intended for use as an internal standard for ... spectrometry. 13(S)-HODE is produced by incubation of linoleic ... been shown to inhibit the adhesion of tumor ...
...
Biology Products: