Navigation Links
Antibiotics: Change route of delivery to mitigate resistance
Date:6/26/2013

ection is often the direct cause of death in many patients with chronic diseases, such as HIV/AIDS and cancer.

Besides resistance, recent work has shown that the use of oral antibiotics can reduce the diversity of the gut flora. Abnormalities of the gut flora are associated with multiple non-infectious diseases, including several autoimmune diseases and type II diabetes, according to Jeremy Nicholson of Imperial College, London, UK. Thus, alternatives to oral administration could likely mitigate these kinds of problems, as well.

Convenient alternatives to oral antibiotics might include transdermal administration via a patch, or other devices, says Wang.

Wang suggests that it should not be surprising that oral administration would abet the spread of resistance genes, since this route, unlike injection, directly exposes the humongous population of gastrointestinal bacteria to antibiotics. The resulting resistant microbes then get transmitted to the environment via the feces. From there, bacteria containing resistance genes once again gain entry to the food supply, via livestock, or via produce that has been exposed to manure from industrial livestock, as well as contaminated waste and soil, in a vicious cycle.

"Revealing this key risk factor is exciting because we have options other than oral administration, including convenient ones, for giving antibiotics," says Wang.


'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Surprise species at risk from climate change
2. DoD-funded research: Can climate change heat up conflict?
3. Land use changes, housing demographics shift in Washington State
4. Epigenetic changes mediated by homocysteine levels in plasma may point to schizophrenia
5. Experts find epigenetic changes moderate reality distortion in schizophrenia patients
6. Metabolic model of E. coli reveals how bacterial growth responds to temperature change
7. Alpine lakes reflect climate change
8. First evidence that the genome can adapt to temperature changes
9. Hidden effects of climate change may threaten eelgrass meadows
10. Microbial changes regulate function of entire ecosystems
11. UCLA life scientists present new insights on climate change and species interactions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/11/2015)... , May 11, 2015  Synaptics Incorporated (NASDAQ: ... interface solutions, today announced the appointment of ... Chief Financial Officer, reporting to Rick Bergman ... current Chief Financial Officer, Kathleen Bayless , ... Mr. Ali brings extensive financial management ...
(Date:5/10/2015)... Fingerprint Cards (FPC) has received an order for ... World Peace Industrial Group (WPI), part of WPG Holdings. WPI ... . Deliveries are planned to take place during Q3 2015 ... China . The order value of 235 ... 1 000 MSEK for 2015.   Jörgen Lantto, acting ...
(Date:5/6/2015)... 2015 LifeBEAM, a developer of bio-sensing technology, ... today that they will expand their partnership in bio-sensing ... cycling helmet and the first joint project between the ... in order to give cyclists more style choices and ... and Lazer announced their plan to release a new ...
Breaking Biology News(10 mins):Synaptics Appoints Wajid Ali as Senior Vice President and Chief Financial Officer 2Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 235 Million 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3
... 2007 Geron Corporation (Nasdaq: GERN) today reported ... embryonic stem cell (hESC)-derived cardiomyocytes improve heart function ... online Aug. 26 in Nature Biotechnology, the landmark ... clinical utility of regenerating damaged heart muscle by ...
... When human heart muscle cells derived from embryonic stem ... attack, they can help rebuild the animal,s heart muscle ... the September issue of Nature Biotechnology. The researchers also ... cells are turned into heart muscle cells and then ...
... in the natural world but so too are cheats ... good but simply reap the benefits of others cooperative ... how cooperation persists despite the threat of cheat takeover ... of Edinburgh and Oxford have found that in bacteria, ...
Cached Biology News:Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction 2Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction 3Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction 4Human derived stem cells can repair rat hearts damaged by heart attack 2Human derived stem cells can repair rat hearts damaged by heart attack 3Social parasites of the smaller kind 2
(Date:5/21/2015)... , May 21, 2015  Prima Biomed Ltd. (NASDAQ: ... is striving to become a leader in the development ... announced that the final CVac data from the Phase ... clear trend for a clinically meaningful improvement in Overall ... remission patients. In the group of second ...
(Date:5/21/2015)... 2015 Patent Offering, The patent’s technology ... or therapeutic imaging within a body lumen (open space). ... having a low cost, single-use disposable illumination and camera ... October 18, 2013 and the patent approval was received ... physician to customize the lighting and magnification of the ...
(Date:5/21/2015)... (PRWEB) May 21, 2015 Veolia’s ... an exclusive North American distribution agreement with VWR ... system. , With more than 160 years of ... and services for laboratory and production facilities, has ... excellence and differentiated services to enable science. ...
(Date:5/20/2015)... 19, 2015 Research and Markets ( ... "Global Cell Therapy Market Outlook 2020 " report ... in tissue and regenerative medicine is expected to have ... which could help in the growth of deregulated organs. ... they are unable to form new tissue or sometimes ...
Breaking Biology Technology:Correction Continues after Big Move - BrokerBank Securities, Inc. 2IpAuctions™ Presents The Worlds Smallest Disposable Illuminated Endoscope For Auction 2IpAuctions™ Presents The Worlds Smallest Disposable Illuminated Endoscope For Auction 3Veolia’s TECTA™ B16 Instrument for E. Coli Detection is Offered Exclusively Through VWR 2Global Cell Therapy Market Outlook 2015-2020 - 262 Cell Therapies & 13 Marketed Cell Therapies 2Global Cell Therapy Market Outlook 2015-2020 - 262 Cell Therapies & 13 Marketed Cell Therapies 3
... CXM ) and its operating unit InnerCool ... was featured on Science,Channel,s "Cool Stuff: How It ... and is scheduled to be rebroadcast at 8:30 ... Please visit, http://science.discovery.com/tv-schedules/series.html for broadcast dates,and times ...
... Squibb,Company (NYSE: BMY ) announced today that it ... $600 million in aggregate principal amount of,5.450% notes due ... amount,of 6.125% notes due May 1, 2038 in an ... J.P. Morgan Securities Inc., and Morgan,Stanley are acting as ...
... Replidyne, Inc.,(Nasdaq: RDYN ) announced today that it will ... P.M. ET to report first quarter 2008,earnings. On Thursday, May ... shareholder meeting at Company headquarters at 1450 Infinite Drive,in Louisville, ... as follows:, Kenneth J. Collins, President and ...
Cached Biology Technology:Cardium Reports on Science Channel Series Featuring InnerCool's Endovascular Cooling During Brain Surgery at Stanford University 2Cardium Reports on Science Channel Series Featuring InnerCool's Endovascular Cooling During Brain Surgery at Stanford University 3Cardium Reports on Science Channel Series Featuring InnerCool's Endovascular Cooling During Brain Surgery at Stanford University 4Cardium Reports on Science Channel Series Featuring InnerCool's Endovascular Cooling During Brain Surgery at Stanford University 5Cardium Reports on Science Channel Series Featuring InnerCool's Endovascular Cooling During Brain Surgery at Stanford University 6Bristol-Myers Squibb Issues $1.6 Billion of Senior Notes 2Replidyne to Report First Quarter 2008 Earnings 2Replidyne to Report First Quarter 2008 Earnings 3
... to deparaffinize and perform Heat Induced Antigen ... sections mounted on glass microscope slides. Deparffinization ... the high temperature used in HIER (over ... paraffin by detergent. Formaldehyde fixation impairs or ...
Fetal Calf Serum Replacement (Bistec) serum...
...
Mouse monoclonal [3A7.A11] to Thymidylate Synthase ( Abpromise for all tested applications). entrezGeneID: 7298 SwissProtID: P04818...
Biology Products: