Navigation Links
Alzheimer's disease therapeutic prevents long-term damage from TBI in pre-clinical studies
Date:3/15/2009

campus of their brain as control mice did," Burns says.

"The experiment with the genetically altered mice shows that amyloid peptide contributes to the secondary damage seen in traumatic brain injury," he says. "If injured mice that cannot develop amyloid demonstrate reduced signs of secondary trauma, that points to amyloid peptide as a cause of this continuing damage."

The study using DAPT then proved that in mice able to produce amyloid, a gamma secretase inhibitor reduced amyloid peptide production, and significantly improved learning, Burns says. "This is an exciting finding that we hope can be readily tested in patients with traumatic brain injury," he says.


'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

1

GOOD

Page: 1 2 3

Related biology news :

1. Paradigm shift in Alzheimerss research: new treatments
2. Iron is involved in prion disease-associated neuronal demise
3. Seeing stem cells helps in fight against peripheral arterial disease
4. Metastatic bone disease patients can walk in Lazarus footsteps
5. Pitt researchers describe molecular 2-step leading to protein clumps of Huntingtons disease
6. Stem cell breakthrough gives new hope to sufferers of muscle-wasting diseases
7. Computer superpower strengthens attempts to combat common diseases
8. Cats eye diseases genetically linked to diseases in humans
9. New discovery paves the way for new diagnosis of serious lung disease
10. Addiction: Insights from Parkinsons disease
11. Portable kit may 1 day detect plant disease before disastrous outbreak
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... A National Science Foundation (NSF) planning grant will help ... a joint program of the University of Illinois at ... , "CARD will be devoted to research in drying ... products; forestry and paper products; chemical products; textiles; and ... of food science and human nutrition and the Illinois ...
(Date:5/20/2013)... (May 20, 2013) - A novel vaccine ... the groundbreaking research that will be unveiled at the ... (NBC). The meeting takes place Monday, May 20 - ... and Marina. , "The main goal of a ... against a pathogen that causes the disease", explained Dr. ...
(Date:5/20/2013)... at the University of Bristol and published online today ... light on how the brain and inner ear developed ... of Earth Sciences, together with Tom Hbner from the ... 150 million year old dinosaurs. , The two palaeontologists ... lettowvorbecki : a very young (juvenile) individual of ...
Breaking Biology News(10 mins):NSF approves planning grant for Center for Advanced Research in Drying 2Germ-fighting vaccine system makes great strides in delivery 2Fossil brain teaser 2
... relocation of an Inuit village already underway, some 400 ... in Alaska for a UN-affiliated conference April 20-24 to ... to both mitigate and adapt to climate change. ... Global Summit on Climate Change is also designed to ...
... U.S. Southwest grew warmer from 18,700 to 10,000 years ago, ... robbing packrats of their favorite food. Now, University of Utah ... the rodents eat toxic creosote bushes that replaced juniper. ... Professor Denise Dearing, senior author of the study, published online ...
... news about pancreatic cancer, one of the most fatal ... the lack of effective therapies: Johns Hopkins University pathologist ... aberrantly active in approximately a third of the 250 ... a presentation April 18, at Experimental Biology 2009 in ...
Cached Biology News:Indigenous peoples at world summit to share climate change observations, coping techniques 2Indigenous peoples at world summit to share climate change observations, coping techniques 3Indigenous peoples at world summit to share climate change observations, coping techniques 4Indigenous peoples at world summit to share climate change observations, coping techniques 5Indigenous peoples at world summit to share climate change observations, coping techniques 6Poison: It's what's for dinner 2Poison: It's what's for dinner 3Poison: It's what's for dinner 4Poison: It's what's for dinner 5Newly discovered epidermal growth factor receptor active in human pancreatic cancers 2
(Date:5/20/2013)... 2013  (PSHR) Pacific Shore Holdings, Inc. a ... a broad range of product categories lines, today ... firm, BlueWater Advisory Group, to provide strategic counsel ... and to direct the company,s outreach and investor ... Matthew Mills , Pacific Shore Holdings, ...
(Date:5/20/2013)... , May 20, 2013  Dr. ... of nucleic acid research, recently launched a new blog ... with Zon ( zon.trilinkbiotech.com ), focuses on what,s trending ... interviews with industry thought leaders, discussions of research presented ... more. Dr. Zon (PhD Princeton University ...
(Date:5/20/2013)... Pacific Biomarkers and Clinigene International are set to unveil ... the 2013 AAPS/ National Biotechnology Conference May ... Marina , San Diego, CA. ... with company representatives at their collaborative seminar, "Biosimilarity, Immunogenicity ... from 1-2 p.m. in the conference,s Spinnaker Room. ...
(Date:5/20/2013)... With bed bugs' presence come problems in various terms. ... to be eliminated, one must make sure that the bed ... so to help bed bug sufferers get that done, it ... bugs without using harmful pesticides. In it, the company ... Bug Bully. , According to My Cleaning Products, contrary to ...
Breaking Biology Technology:Pacific Shore Holdings Retains Investor Relations Firm 2Dr. Gerald 'Jerry' Zon Launches New Blog for TriLink BioTechnologies 2Pacific Biomarkers and Clinigene International To Announce Laboratory Solutions for Developers of Biosimilars at 2013 AAPS/ National Biotechnology Conference 2New Non Pesticide Discovery on How to Get Rid of Bed Bugs Tipped by My Cleaning Products 2
... 24, 2011 Zeltia Group,s net revenues totaled 153.5 ... percent more than in 2009 (123.4 million euro, or ... to a 70 percent increase in Yondelis® sales. ... 79.4 million euro (approximately 109.3 million USD) in 2010 ...
... Reportlinker.com announces that a new market research ... Propylene Oxide: 2010 World Market Outlook And ... The report analyzes worldwide markets for Propylene ... America. It provides the most complete and current ...
... PITTSBURGH, Feb. 24, 2011 Mylan Inc. (Nasdaq: MYL ... months ended December 31, 2010, and provided its financial guidance for ... diluted EPS of $0.45 for the quarter ended December 31, 2010 ... of 36%; Adjusted diluted EPS of $1.61 for the ...
Cached Biology Technology:74 Percent EBITDA Improvement at Zeltia Group in 2010 2Reportlinker Adds Propylene Oxide: 2010 World Market Outlook and Forecast 2Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 2Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 3Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 4Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 5Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 6Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 7Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 8Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 9Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 10Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 11Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 12Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 13Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 14Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 15Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 16Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 17Mylan Reports Adjusted Diluted EPS of $0.45 for the Quarter, a 36% Increase over Prior Year Quarter; and $1.61 for the Year, a 24% Increase over Prior Year 18
Rabbit Anti-Human Janus Kinase 2 (JAK2 Polyclonal Antibody Family: Protein Kinase Sub-Family: TYK2/JAK Applications: ELISA, Western Blot...
MAb to HSV-2, gG-2 HSV-2 Glycoprotein G-2...
Immunogen for A300-655A was a phosphorylated synthetic peptide, which represented a portion of human RNA Polymerase II (GeneID 5430) around serine 5 of the C-terminal repeat YSPTSPS....
human Exodus-2 Research Focus: cytokine/growth factor Storage Temperature: -20C Shipping Temperature: 4C...
Biology Products: