In this paper, researchers explain how the index can be used by assessing trends in resistance associated with two disease-causing micro-organisms: Escherichia coli and Acinetobacter baumannii. The index can also illuminate how physicians adapt to trends in resistance. For example, in this analysis, the index showed how physicians were able to use other drugs to treat infections caused by resistant strains of E. coli but had very few options left for treating Acinetobacter, a superbug that increasingly is resistant to all available antibiotics.
"Mapping the geography of antibiotic use and summarizing their effectiveness with a Drug Resistance Index bring us one step closer to the solutions we urgently need in order to curtail this public health crisis," Laxminarayan said. "If we do nothing, resistance will continue to develop and our most valuable antibiotics ultimately will fail."
Extending the Cure research suggests that policymakers must address the broader problem of antibiotic resistance by putting comprehensive solutions in place, including better infection control and surveillance as well as stepping up efforts to curtail overuse of antibiotics, a solution that would help preserve the power of the drugs we have left on the shelf.
|Contact: Kathy Fackelmann|