Navigation Links
Air pollution and genetics combine to increase risk for autism
Date:12/1/2013

Exposure to air pollution appears to increase the risk for autism among people who carry a genetic disposition for the neurodevelopmental disorder, according to newly published research led by scientists at the Keck School of Medicine of the University of Southern California (USC).

"Our research shows that children with both the risk genotype and exposure to high air pollutant levels were at increased risk of autism spectrum disorder compared to those without the risk genotype and lower air pollution exposure," said the study's first author, Heather E. Volk, Ph.D., M.P.H., assistant professor of research in preventive medicine and pediatrics at the Keck School of Medicine of USC and principal investigator at The Saban Research Institute of Children's Hospital Los Angeles.

The study, "Autism spectrum disorder: Interaction of air pollution with the MET receptor tyrosine kinase gene," is scheduled to appear in the January 2014 edition of Epidemiology.

Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disability characterized by problems with social interaction, communication and repetitive behaviors. The Centers for Disease Control and Prevention estimates that one in 88 children in the United States has an ASD.

ASD is highly heritable, suggesting that genetics are an important contributing factor, but many questions about its causes remain. There currently is no cure for the disorder.

"Although gene-environment interactions are widely believed to contribute to autism risk, this is the first demonstration of a specific interaction between a well-established genetic risk factor and an environmental factor that independently contribute to autism risk," said Daniel B. Campbell, Ph.D., assistant professor of psychiatry and the behavioral sciences at the Keck School of Medicine of USC and the study's senior author. "The MET gene variant has been associated with autism in multiple studies, controls expres
'/>"/>

Contact: Alison Trinidad
alison.trinidad@usc.edu
323-442-3941
University of Southern California - Health Sciences
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Large study shows pollution impact on coral reefs -- and offers solution
2. X-ray science taps bug biology to design better materials and reduce pollution
3. Death & disability from air pollution down 35 percent in the US
4. Red cedar tree study shows that Clean Air Act is reducing pollution, improving forests
5. Safe levels of environmental pollution may have long-term health consequences
6. Traffic pollution and wood smoke increases asthma in adults
7. Stop marine pollution to protect kelp forests
8. Innovative MIT study estimates extent to which air pollution in China shortens human lives
9. Exposure to high pollution levels during pregnancy may increase risk of having child with autism
10. Oldest record of human-caused lead pollution detected
11. Microplastic pollution prevalent in lakes too
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Air pollution and genetics combine to increase risk for autism
(Date:4/2/2015)... 2015 At its 2015 ACMG Annual Clinical ... , the American College of Medical Genetics and Genomics ... its Board.  Members of the ACMG Board of Directors ... and advancing its policies and programs. ACMG is the ... "It,s an eventful time in medical genetics and genomics.  ...
(Date:4/2/2015)... Fingerprint Cards (FPC) has received ... the distributor World Peace Industrial Group (WPI), part of ... the major part of the shipments will take place ... smartphone manufacturers in China . The ... communicated revenue guidance of + 1 000 MSEK for 2015.  ...
(Date:4/1/2015)... , April 1, 2015   Medisafe ™, ... million users across iOS and Android ... begun integrating biofeedback into the platform to allow patients ... outcomes. For the first time, patients will be able ... a dose impacts important biometrics, such as glucose levels ...
Breaking Biology News(10 mins):American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2
... ever met a cat that doesn't go crazy over catnip? ... world don't respond to it at all, according to the ... Chemical & Engineering News, the weekly newsmagazine published by the ... sensitivity is inherited, says Carolyn M. McDaniel, a veterinarian at ...
... responsible for controlling a first key step in the creation ... journal Nature tomorrow (Thursday 27 October 2005). , The gene, ... once a sperm enters an egg, giving it a crucial ... , The absence or mutation of this gene in the ...
... China have an increased risk of schizophrenia, consistent with ... and schizophrenia, according to a study in the August ... and human rights. , Schizophrenia is a common form ... and delusions, as well a as deterioration of social ...
Cached Biology News:Many cats unaffected by catnip, C&EN reports 2Scientists unpick genetics of first 15 minutes of life 2Prenatal exposure to famine increases risk of schizophrenia 2
(Date:4/16/2015)... 2015 /PRNewswire/ - Portage Biotech Inc. ("Portage" or "the ... is pleased to announce that the Company will be ... 2015 to be held in London, UK ... and Mr. James Mellon , a director of ... the key programs at its subsidiaries, Portage Pharmaceuticals Ltd. ...
(Date:4/16/2015)... A new infographic compiles useful information ... institutions to learn how Appleā€™s new framework can change ... is ideal since Apple made Research Kit ... open-source framework for developing medical research apps that Apple ... researchers to collect secure clinical data and communicate via ...
(Date:4/16/2015)...  EMD Serono today announced the US biopharmaceutical ... , appointed Alise Reicin , MD, ... Development.  Dr. Reicin brings extensive research and early/late ... Immunology. She is an accomplished pharmaceutical executive with ... President in various capacities across R&D at MSD ...
(Date:4/16/2015)... April 16, 2015  Northwest Biotherapeutics, Inc. (NASDAQ: ... developing non-toxic DCVax® personalized immune therapies for cancer, ... the Loncar Cancer Immunotherapy Index (LCINDX), a professional ... the immunotherapy field within the biotechnology space.  ... top 25 companies" in the immunotherapy space, including ...
Breaking Biology Technology:Portage to Present at Master Investor 2015 in London, UK 2Portage to Present at Master Investor 2015 in London, UK 3Portage to Present at Master Investor 2015 in London, UK 4Infographic Illustrates Potential for Research Kit to Impact Clinical Research 2Infographic Illustrates Potential for Research Kit to Impact Clinical Research 3Alise Reicin Joins the Biopharmaceutical Business of Merck KGaA, Darmstadt, Germany as Head of Global Clinical Development 2Alise Reicin Joins the Biopharmaceutical Business of Merck KGaA, Darmstadt, Germany as Head of Global Clinical Development 3NW Bio Included In New Index Of The "Top 25 Cancer Immunotherapy Companies" 2NW Bio Included In New Index Of The "Top 25 Cancer Immunotherapy Companies" 3
... Millstone Medical Outsourcing,announced today that the company ... accommodate growing business with new and existing customers ... new facility, located at,580 Commerce Drive, includes 27,000 ... advanced inspection services, ultrasonic cleaning,and sterile and non-sterile ...
... six-year battle with heart disease that included numerous medications, trips to the ... himself in the Intensive Care Unit at an Ohio hospital. Both sides ... a transplant. , ... TUCSON, Ariz. (Business Wire EON) October 8, ...
... from Top Industry Analyst -, EVANSTON, Ill., ... across industries manage a wide range of sales ... a global management,consulting firm specializing in sales and ... new Javelin(TM) Software Suite provides a unified platform ...
Cached Biology Technology:Millstone Medical Outsourcing Acquires New Facility to Accommodate Growing Business, Provide Additional Clean Room Capacity 2 "Put Down the BBQ Ribs, We've Found You a Donor Heart," Nurse Tells Patient : Ohio Father near Death Gets Second Chance at Life with CardioWest™ temporary Total Artificial Heart 2Newly Integrated Software Suite From ZS Associates Offers Comprehensive Set of Sales Performance Management Software Solutions 2Newly Integrated Software Suite From ZS Associates Offers Comprehensive Set of Sales Performance Management Software Solutions 3
... Neogens enzyme-linked immunosorbent assay (ELISA) test ... screening devices for the detection of drugs ... kits are intended for forensic use only. ... be confirmed by a quantitative method such ...
... that noncovalently binds and inactivates neutral pancreatic RNase ... 1, T1, T2, H, U1, U2 or CL3. ... in that it has a more robust interaction ... in the absence of DTT or other reducing ...
...
UGT1A7 (E-15)...
Biology Products: