Navigation Links
African-American, Caucasian women should take identical vitamin D doses
Date:2/11/2013

Chevy Chase, MD African-American women battling vitamin D deficiencies need the same dose as Caucasian women to treat the condition, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Although women with darker skin tones tend to have lower levels of the biomarker used to measure Vitamin D levels, called 25-hydroxyvitamin D or 25OHD, the study found that older African-American and Caucasian women responded in the same way when they received vitamin D supplements.

Unlike many vitamins that are absorbed primarily from foods, the body's main source of vitamin D is sunlight. Vitamin D deficiency, which is primarily caused by inadequate exposure to sunlight and very poor diet, can result in abnormalities in calcium, phosphorus and bone metabolism. Vitamin D deficiency can cause rickets in children or a bone-softening condition called osteomalacia and muscle weakness in adults.

In a double-blind study that gave varying vitamin D doses to African-American and Caucasian women of similar body size, levels of the 25OHD biomarker were very similar. The findings suggest that vitamin D absorption and metabolism is the same in both groups. Researchers concluded that African-American women tend to have lower levels of the biomarker 25OHD because they naturally produce less vitamin D in the skin after sunlight exposure.

"African-American women don't have to worry about taking larger doses of vitamin D to compensate," said J. Chris Gallagher, MD, of Creighton University School of Medicine in Omaha, Neb., and lead author of the study. "They should follow the current medical guidelines for vitamin D supplementation suggested recently by the Institute of Medicine."

The Endocrine Society has issued a separate set of clinical practice guidelines governing vitamin D dosage. The guidelines are available at http://www.endo-society.org/guidelines/final/upload/FINAL-Standalone-Vitamin-D-Guideline.pdf.

Previously there was no research in minority populations to determine whether the same guidelines applied to them. Researchers designed this study to develop dosing guidelines for older African-American women. The study, which looked at vitamin D doses in 110 African-American women between the ages of 57 and 90, was the first randomized controlled dose response study conducted in this population.

"We saw a real need to study optimal vitamin D doses in African-American women and help their health care professionals make informed medical decisions," Gallagher said.

Although exposure to sunlight increases vitamin D levels, concerns about melanoma and other types of skin cancer necessitate avoidance of excessive exposure to the sun.


'/>"/>

Contact: Jenni Glenn Gingery
jgingery@endo-society.org
301-941-0240
The Endocrine Society
Source:Eurekalert

Related biology news :

1. Cancer risk for African-American women with benign breast disease factors Wayne State finds
2. Few pregnant women treated for sexually transmitted infections
3. Geneviève Almouzni to receive the 2013 FEBS
4. EMBO Women in Science Award
5. Abuse during childhood linked to uterine fibroids in African-American women
6. Women must do more to reap same positive health outcomes as men, MU research suggests
7. Vaginal delivery is the safest option for women with pelvic girdle pain
8. Scientists pinpoint molecular signals that make some women prone to miscarriage
9. Virtual women reveal more skin, regardless of body proportions
10. Overweight pregnant women not getting proper weight-gain advice
11. Abuse during childhood linked to adult-onset asthma in African-American women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2016)... R.I. , March 31, 2016  Genomics firm ... of founding CEO, Barrett Bready , M.D., who ... members of the original technical leadership team, including Chief ... President of Product Development, Steve Nurnberg and Vice President ... returned to the company. Dr. Bready served ...
(Date:3/23/2016)... March 23, 2016 ... Sicherheit Gesichts- und Stimmerkennung mit Passwörtern ... (NASDAQ: MESG ), ein führender Anbieter ... Unternehmen mit SpeechPro zusammenarbeitet, um erstmals dessen ... wird die Möglichkeit angeboten, im Rahmen mobiler ...
(Date:3/22/2016)... Ontario , PROVO and ... Newborn Screening Ontario (NSO), which operates the ... for molecular testing, and Tute Genomics and UNIConnect, ... management technology respectively, today announced the launch of a ... next-generation sequencing (NGS) testing panel. NSO ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of commercial spectrophotometers and fluorometers ... the 6000i models are higher end machines that use the more unconventional z-dimension of ... beam from the bottom of the cuvette holder. , FireflySci has developed several ...
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
(Date:6/23/2016)... 2016  The Biodesign Challenge (BDC), a university competition ... harness living systems and biotechnology, announced its winning teams ... New York City . The ... projects at MoMA,s Celeste Bartos Theater during the daylong ... senior curator of architecture and design, and Suzanne ...
(Date:6/23/2016)... Apellis Pharmaceuticals, Inc. today announced positive ... its complement C3 inhibitor, APL-2. The trials were ... studies designed to assess the safety, tolerability, pharmacokinetics ... healthy adult volunteers. Forty subjects were ... dose (ranging from 45 to 1,440mg) or repeated ...
Breaking Biology Technology: